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Accession:CHEBI:16010 term browser browse the term
Definition:An oxoproline having the oxo group placed at the 5-position. It is an intermediate metabolite in the glutathione cycle.
Synonyms:exact_synonym: 5-oxopyrrolidine-2-carboxylic acid
 related_synonym: 2-pyrrolidone-5-carboxylic acid;   5-oxo-DL-proline;   Formula=C5H7NO3;   Glp;   InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9);   InChIKey=ODHCTXKNWHHXJC-UHFFFAOYSA-N;   Pyroglutamate;   Pyroglutamic acid;   SMILES=OC(=O)C1CCC(=O)N1
 alt_id: CHEBI:12157;   CHEBI:20624;   CHEBI:2116;   CHEBI:44943
 xref: Beilstein:82131 "Beilstein";   CAS:149-87-1 "ChemIDplus";   CAS:149-87-1 "NIST Chemistry WebBook";   PMID:17439666 "Europe PMC";   PMID:22770225 "Europe PMC";   PMID:23217740 "Europe PMC";   Reaxys:82131 "Reaxys";   Wikipedia:Pyroglutamic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:57606

show annotations for term's descendants       view all columns           Sort by:
5-oxo-L-proline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dek DEK proto-oncogene JBrowse link 17 17,965,872 17,987,836 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        biochemical role 19179
          metabolite 19151
            eukaryotic metabolite 18770
              animal metabolite 18511
                mammalian metabolite 18493
                  human metabolite 18133
                    5-oxoproline 2
                      5-oxo-D-proline 0
                      5-oxo-L-proline + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      carboxylic acid 17940
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16630
                                              carboxamide 16630
                                                lactam 2976
                                                  gamma-lactam 508
                                                    pyrrolidin-2-ones 131
                                                      5-oxoproline 2
                                                        5-oxo-D-proline 0
                                                        5-oxo-L-proline + 2
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.