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ONTOLOGY REPORT - ANNOTATIONS


Term:lipopolysaccharide
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Accession:CHEBI:16412 term browser browse the term
Definition:Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Synonyms:related_synonym: LPS;   lipopolysaccharides
 alt_id: CHEBI:14520;   CHEBI:25062;   CHEBI:6494;   MESH:D008070
 xref: KEGG:C00338
 xref_mesh: MESH:D008070
 xref: PMID:15589368 "Europe PMC";   PMID:24186868 "Europe PMC";   PMID:24506665 "Europe PMC";   PMID:24642373 "Europe PMC";   PMID:24659348 "Europe PMC"


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lipopolysaccharide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ALB albumin JBrowse link 8 69,643,427 69,663,152 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 1 158,337,403 158,518,214 RGD:6480464
G CASP6 caspase 6 JBrowse link 8 112,519,450 112,534,315 RGD:6480464
G CCL2 chemokine (C-C motif) ligand 2 JBrowse link 12 40,798,109 40,800,013 RGD:6480464
G CCL20 C-C motif chemokine ligand 20 JBrowse link 15 129,172,743 129,176,069 RGD:6480464
G CFLAR CASP8 and FADD like apoptosis regulator JBrowse link 15 104,780,744 104,835,631 RGD:6480464
G CLDN1 claudin 1 JBrowse link 13 127,714,857 127,730,628 RGD:6480464
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 8 69,932,646 69,935,861 RGD:6480464
G DIABLO diablo IAP-binding mitochondrial protein JBrowse link 14 30,498,885 30,519,846 RGD:6480464
G GRHPR glyoxylate and hydroxypyruvate reductase JBrowse link 1 238,139,764 238,151,631 RGD:6480464
G HSPA14 heat shock protein family A (Hsp70) member 14 JBrowse link 10 46,908,161 46,935,323 RGD:6480464
G IFNG interferon gamma JBrowse link 5 32,477,906 32,482,670 RGD:6480464
G IL10 interleukin 10 JBrowse link 9 67,400,727 67,405,941 RGD:6480464
G IL12A interleukin 12A JBrowse link 13 99,733,394 99,741,078 RGD:6480464
G IL13 interleukin 13 JBrowse link 2 134,972,099 134,976,672 RGD:6480464
G IL17A interleukin 17A JBrowse link 7 46,013,584 46,017,161 RGD:6480464
G IL1A interleukin 1 alpha JBrowse link 3 43,718,320 43,731,668 RGD:6480464
G IL6 interleukin 6 JBrowse link 9 91,506,421 91,510,830 RGD:6480464
G INS insulin JBrowse link 2 1,496,842 1,498,052 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 14 50,083,079 50,165,528 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 3 18,291,444 18,299,410 RGD:6480464
G MCL1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 4 98,562,092 98,567,014 RGD:6480464
G MYD88 MYD88 innate immune signal transduction adaptor JBrowse link 13 22,976,951 22,979,568 RGD:6480464
G NCF1 neutrophil cytosolic factor 1 JBrowse link 3 11,820,367 11,834,394 RGD:6480464
G NCF2 neutrophil cytosolic factor 2 JBrowse link 9 124,776,516 124,813,358 RGD:6480464
G NCF4 neutrophil cytosolic factor 4 JBrowse link 5 10,876,147 10,994,002 RGD:6480464
G NOS2 nitric oxide synthase 2 JBrowse link 12 44,174,944 44,219,875 RGD:6480464
G PTGS2 prostaglandin-endoperoxide synthase 2 JBrowse link 9 127,850,164 127,858,866 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 2 6,594,869 6,602,684 RGD:6480464
G ROCK1 Rho associated coiled-coil containing protein kinase 1 JBrowse link 6 106,163,899 106,314,998 RGD:6480464
G SELE selectin E JBrowse link 4 81,289,061 81,299,657 RGD:6480464
G SIRPA signal regulatory protein alpha JBrowse link 17 33,566,270 33,611,375 RGD:6480464
G SLC38A1 solute carrier family 38 member 1 JBrowse link 5 77,009,840 77,076,723 RGD:6480464
G SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 JBrowse link 2 69,717,175 69,810,301 RGD:6480464
G TLR4 toll like receptor 4 JBrowse link 1 258,044,610 258,054,641 RGD:6480464
G TNF tumor necrosis factor JBrowse link 7 23,699,635 23,702,393 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 838
    chemical entity 838
      molecular entity 836
        polyatomic entity 800
          macromolecule 54
            biomacromolecule 49
              polysaccharide derivative 49
                lipopolysaccharide 37
                  3-deoxyoctulosonyllipopolysaccharide 0
                  Cosmosporaside D, (rel)- 0
                  Cosmosporaside E, (rel)- 0
                  E. coli strain 0111 B4 lipopolysaccharide 0
                  Glucoselysine 0
                  HCH-acetylsalicortin 0
                  LSM-36656 0
                  LSM-36728 0
                  LSM-36730 0
                  LSM-36740 0
                  N-acetyl-D-glucosaminyllipopolysaccharides 0
                  N-acetyl-beta-D-mannosaminouronosyl-(1->4)-lipopolysaccharide 0
                  citrusoside A 0
                  citrusoside B 0
                  citrusoside C 0
                  citrusoside D 0
                  galactosyllipopolysaccharide + 0
                  glucosyllipopolysaccharide + 0
                  soldanelline B 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 838
    subatomic particle 822
      composite particle 822
        hadron 822
          baryon 822
            nucleon 822
              atomic nucleus 822
                atom 822
                  main group element atom 810
                    p-block element atom 807
                      carbon group element atom 778
                        carbon atom 774
                          organic molecular entity 774
                            heteroorganic entity 531
                              organochalcogen compound 496
                                organooxygen compound 431
                                  carbohydrates and carbohydrate derivatives 109
                                    carbohydrate 109
                                      polysaccharide 49
                                        polysaccharide derivative 49
                                          O-polysaccharide 37
                                            lipopolysaccharide 37
                                              3-deoxyoctulosonyllipopolysaccharide 0
                                              Cosmosporaside D, (rel)- 0
                                              Cosmosporaside E, (rel)- 0
                                              E. coli strain 0111 B4 lipopolysaccharide 0
                                              Glucoselysine 0
                                              HCH-acetylsalicortin 0
                                              LSM-36656 0
                                              LSM-36728 0
                                              LSM-36730 0
                                              LSM-36740 0
                                              N-acetyl-D-glucosaminyllipopolysaccharides 0
                                              N-acetyl-beta-D-mannosaminouronosyl-(1->4)-lipopolysaccharide 0
                                              citrusoside A 0
                                              citrusoside B 0
                                              citrusoside C 0
                                              citrusoside D 0
                                              galactosyllipopolysaccharide + 0
                                              glucosyllipopolysaccharide + 0
                                              soldanelline B 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.