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ONTOLOGY REPORT - ANNOTATIONS


Term:CDP-choline
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Accession:CHEBI:16436 term browser browse the term
Definition:A member of the class of phosphocholines that is the chloine ester of CDP. It is an intermediate obtained in the biosynthetic pathway of structural phospholipids in cell membranes.
Synonyms:exact_synonym: 5'-O-[hydroxy({[2-(trimethylammonio)ethoxy]phosphinato}oxy)phosphoryl]cytidine
 related_synonym: CDP-colina;   Citicoline;   Cytidindiphosphocholin;   Cytidine 5'-diphosphocholine;   Formula=C14H26N4O11P2;   InChI=1S/C14H26N4O11P2/c1-18(2,3)6-7-26-30(22,23)29-31(24,25)27-8-9-11(19)12(20)13(28-9)17-5-4-10(15)16-14(17)21/h4-5,9,11-13,19-20H,6-8H2,1-3H3,(H3-,15,16,21,22,23,24,25)/t9-,11-,12-,13-/m1/s1;   InChIKey=RZZPDXZPRHQOCG-OJAKKHQRSA-N;   SMILES=C[N+](C)(C)CCOP([O-])(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(N)nc1=O;   [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM;   citicolina;   citicolinum;   citidin difosfato de colina;   cyticholine;   cytidine 5'-(choline diphosphate);   cytidine 5'-(cholinyl pyrophosphate);   cytidine 5'-diphosphoric choline
 alt_id: CHEBI:13268;   CHEBI:20867;   CHEBI:3268;   CHEBI:41440
 xref: Beilstein:4170138 "ChemIDplus";   CAS:987-78-0 "ChemIDplus";   CAS:987-78-0 "KEGG COMPOUND";   DrugBank:DB04290;   Drug_Central:664 "DrugCentral";   HMDB:HMDB0001413;   KEGG:C00307;   KEGG:D00057;   KNApSAcK:C00007231
 xref_mesh: MESH:D003566
 xref: PDBeChem:CDC;   PMID:10701532 "Europe PMC";   PMID:10796523 "Europe PMC";   PMID:8709678 "Europe PMC";   Reaxys:4170138 "Reaxys";   Wikipedia:Citicoline
 cyclic_relationship: is_conjugate_base_of CHEBI:49086


show annotations for term's descendants       view all columns           Sort by:
 
CDP-choline term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Nceh1 neutral cholesterol ester hydrolase 1 JBrowse link 2 112,868,834 112,932,622 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            central nervous system drug 16254
              psychotropic drug 14981
                CDP-choline 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      chalcogen 19233
                        oxygen atom 19188
                          oxygen molecular entity 19188
                            hydroxides 18965
                              oxoacid 18076
                                pnictogen oxoacid 8534
                                  phosphorus oxoacid 8429
                                    phosphoric acids 7314
                                      phosphoric acid 7314
                                        phosphoric acid derivative 6965
                                          phosphate 6965
                                            organic phosphate 6964
                                              carbohydrate phosphate 1496
                                                phospho sugar 1431
                                                  aldose phosphate 1429
                                                    aldopentose phosphate 1423
                                                      ribose phosphate 1417
                                                        ribonucleotide 1376
                                                          ribonucleoside 5'-phosphate 385
                                                            ribonucleoside 5'-diphosphate 104
                                                              pyrimidine ribonucleoside 5'-diphosphate 19
                                                                CDP 5
                                                                  CDP-choline 5
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