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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dGTP
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Accession:CHEBI:16497 term browser browse the term
Definition:A purine 2'-deoxyribonucleoside 5'-triphosphate having guanine as the nucleobase.
Synonyms:exact_synonym: 2'-deoxyguanosine 5'-(tetrahydrogen triphosphate)
 related_synonym: 2'-Deoxyguanosine 5'-triphosphate;   Deoxyguanosine 5'-triphosphate;   Deoxyguanosine triphosphate;   Formula=C10H16N5O13P3;   InChI=1S/C10H16N5O13P3/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(26-6)2-25-30(21,22)28-31(23,24)27-29(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1;   InChIKey=HAAZLUGHYHWQIW-KVQBGUIXSA-N;   SMILES=Nc1nc2n(cnc2c(=O)[nH]1)[C@H]1C[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1
 alt_id: CHEBI:10497;   CHEBI:14076;   CHEBI:19247
 xref: CAS:2564-35-4;   DrugBank:DB02181;   ECMDB:ECMDB01440;   HMDB:HMDB0001440;   KEGG:C00286;   KNApSAcK:C00019346
 xref_mesh: MESH:C029603
 xref: PDBeChem:DGT;   PMID:11096070;   PMID:22844265;   PMID:7929110;   Reaxys:73481;   YMDB:YMDB00744
 cyclic_relationship: is_conjugate_acid_of CHEBI:57794


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dGTP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 decreases abundance ISO SAMHD1 protein results in decreased abundance of deoxyguanosine triphosphate CTD PMID:26342080 NCBI chr 3:153,210,829...153,250,705
Ensembl chr 3:153,210,829...153,250,641
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      biological role 19734
        biochemical role 19282
          metabolite 19263
            eukaryotic metabolite 18908
              fungal metabolite 17411
                Saccharomyces cerevisiae metabolite 16472
                  dGTP 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      chalcogen 19362
                        oxygen atom 19323
                          oxygen molecular entity 19323
                            hydroxides 19068
                              oxoacid 18193
                                pnictogen oxoacid 10146
                                  phosphorus oxoacid 9033
                                    phosphoric acids 7795
                                      phosphoric acid 7795
                                        phosphoric acid derivative 7474
                                          phosphate 7474
                                            organic phosphate 7473
                                              carbohydrate phosphate 1529
                                                phospho sugar 1455
                                                  aldose phosphate 1453
                                                    aldopentose phosphate 1447
                                                      deoxyaldopentose phosphate 9
                                                        2-deoxyribose phosphate 9
                                                          2'-deoxyribonucleotide 8
                                                            2'-deoxyribonucleoside 5'-phosphate 8
                                                              2'-deoxyribonucleoside 5'-triphosphate 3
                                                                purine 2'-deoxyribonucleoside 5'-triphosphate 1
                                                                  dGTP 1
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