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ONTOLOGY REPORT - ANNOTATIONS


Term:1,4-benzoquinone
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Accession:CHEBI:16509 term browser browse the term
Definition:The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.
Synonyms:exact_synonym: cyclohexa-2,5-diene-1,4-dione
 related_synonym: 1,4-Benzochinon;   2,5-Cyclohexadiene-1,4-dione;   Formula=C6H4O2;   InChI=1S/C6H4O2/c7-5-1-2-6(8)4-3-5/h1-4H;   InChIKey=AZQWKYJCGOJGHM-UHFFFAOYSA-N;   Para-Benzoquinone;   Quinone;   SMILES=O=C1C=CC(=O)C=C1;   benzo-1,4-quinone;   benzoquinone;   p-Benzoquinone;   p-Chinon;   p-Quinone
 alt_id: CHEBI:12837;   CHEBI:15009;   CHEBI:18927;   CHEBI:49820;   CHEBI:8730
 xref: Beilstein:773967 "Beilstein";   CAS:106-51-4 "ChemIDplus";   CAS:106-51-4 "KEGG COMPOUND";   CAS:106-51-4 "NIST Chemistry WebBook";   Gmelin:2741 "Gmelin";   HMDB:HMDB0003364;   KEGG:C00472;   KEGG:C15602
 xref_mesh: MESH:C004532
 xref: MetaCyc:P-BENZOQUINONE;   PDBeChem:PLQ;   PMID:10462055 "Europe PMC";   PMID:11304127 "Europe PMC";   PMID:1395635 "Europe PMC";   PMID:15182198 "Europe PMC";   PMID:15618234 "Europe PMC";   PMID:15920754 "Europe PMC";   PMID:16484134 "Europe PMC";   PMID:24023812 "Europe PMC";   PMID:25057895 "Europe PMC";   PMID:9118901 "Europe PMC";   Reaxys:773967 "Reaxys";   UM-BBD_compID:c0261 "UM-BBD";   Wikipedia:1\,4-Benzoquinone


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1,4-benzoquinone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Bach1 BTB domain and CNC homolog 1 JBrowse link 11 27,364,913 27,398,713 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:6480464
G Bmi1 BMI1 proto-oncogene, polycomb ring finger JBrowse link 17 85,360,439 85,370,283 RGD:6480464
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp7 caspase 7 JBrowse link 1 277,190,557 277,242,779 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl11 C-C motif chemokine ligand 11 JBrowse link 10 69,434,965 69,439,566 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Ccl4 C-C motif chemokine ligand 4 JBrowse link 10 70,870,926 70,886,357 RGD:6480464
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cryaa crystallin, alpha A JBrowse link 20 10,438,444 10,442,189 RGD:6480464
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:6480464
G Csf2 colony stimulating factor 2 JBrowse link 10 39,602,089 39,604,070 RGD:6480464
G Cxcl12 C-X-C motif chemokine ligand 12 JBrowse link 4 149,261,044 149,273,891 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Dhrs7 dehydrogenase/reductase 7 JBrowse link 6 95,522,577 95,541,393 RGD:6480464
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 JBrowse link 1 248,952,896 248,956,579 RGD:6480464
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:6480464
G Gbp1 guanylate binding protein 1 JBrowse link 2 248,343,334 248,423,402 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Gss glutathione synthetase JBrowse link 3 151,076,254 151,106,557 RGD:6480464
G H2ax H2A.X variant histone JBrowse link 8 48,665,652 48,666,981 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hoxb4 homeo box B4 JBrowse link 10 84,167,331 84,169,913 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Irf1 interferon regulatory factor 1 JBrowse link 10 39,109,530 39,116,532 RGD:6480464
G Jag1 jagged canonical Notch ligand 1 JBrowse link 3 130,079,361 130,114,781 RGD:6480464
G Kdr kinase insert domain receptor JBrowse link 14 34,727,677 34,787,127 RGD:6480464
G Kitlg KIT ligand JBrowse link 7 42,269,784 42,351,054 RGD:6480464
G Ldha lactate dehydrogenase A JBrowse link 1 102,900,288 102,909,713 RGD:6480464
G Maff MAF bZIP transcription factor F JBrowse link 7 120,580,743 120,592,095 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mapt microtubule-associated protein tau JBrowse link 10 92,289,002 92,386,517 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Mt1 metallothionein 1 JBrowse link 19 11,301,991 11,303,007 RGD:6480464
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nox1 NADPH oxidase 1 JBrowse link X 104,909,328 104,932,508 RGD:6480464
G Nox4 NADPH oxidase 4 JBrowse link 1 150,796,359 150,976,186 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Ogg1 8-oxoguanine DNA glycosylase JBrowse link 4 145,282,828 145,289,367 RGD:6480464
G Pdk1 pyruvate dehydrogenase kinase 1 JBrowse link 3 58,530,870 58,561,494 RGD:6480464
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 JBrowse link 17 70,632,778 70,713,736 RGD:6480464
G Pfkl phosphofructokinase, liver type JBrowse link 20 11,393,860 11,415,889 RGD:6480464
G Pgk1 phosphoglycerate kinase 1 JBrowse link X 77,263,399 77,279,373 RGD:6480464
G Pink1 PTEN induced kinase 1 JBrowse link 5 156,677,146 156,689,258 RGD:6480464
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:6480464
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:6480464
G Ptpn2 protein tyrosine phosphatase, non-receptor type 2 JBrowse link 18 63,415,298 63,489,240 RGD:6480464
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:6480464
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6480464
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:6480464
N-acetyl-1,4-benzoquinone imine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Adarb2 adenosine deaminase, RNA-specific, B2 JBrowse link 17 58,098,979 58,653,137 RGD:6480464
G Alcam activated leukocyte cell adhesion molecule JBrowse link 11 50,780,735 50,985,083 RGD:6480464
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 JBrowse link 1 127,302,920 127,337,828 RGD:6480464
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:6480464
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:6480464
G Cald1 caldesmon 1 JBrowse link 4 62,103,948 62,291,375 RGD:6480464
G Ccdc25 coiled-coil domain containing 25 JBrowse link 15 42,522,108 42,555,318 RGD:6480464
G Cd9 CD9 molecule JBrowse link 4 157,977,163 158,010,091 RGD:6480464
G Cep44 centrosomal protein 44 JBrowse link 16 37,177,379 37,199,043 RGD:6480464
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Col1a2 collagen type I alpha 2 chain JBrowse link 4 31,534,225 31,569,152 RGD:6480464
G Col3a1 collagen type III alpha 1 chain JBrowse link 9 52,023,295 52,059,221 RGD:6480464
G Cpa6 carboxypeptidase A6 JBrowse link 5 8,215,443 8,574,655 RGD:6480464
G Cst5 cystatin D JBrowse link 3 144,569,502 144,574,112 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Dmrt1 doublesex and mab-3 related transcription factor 1 JBrowse link 1 243,477,403 243,582,629 RGD:6480464
G Dnttip1 deoxynucleotidyltransferase, terminal, interacting protein 1 JBrowse link 3 161,212,156 161,235,749 RGD:6480464
G Dsc3 desmocollin 3 JBrowse link 18 11,753,047 11,789,846 RGD:6480464
G Etnk2 ethanolamine kinase 2 JBrowse link 13 50,481,178 50,498,991 RGD:6480464
G Fbxo39 F-box protein 39 JBrowse link 10 58,874,028 58,878,445 RGD:6480464
G Frk fyn-related Src family tyrosine kinase JBrowse link 20 41,266,408 41,383,731 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Hdac4 histone deacetylase 4 JBrowse link 9 99,052,945 99,299,715 RGD:6480464
G Hid1 HID1 domain containing JBrowse link 10 103,899,160 103,919,649 RGD:6480464
G Il23r interleukin 23 receptor JBrowse link 4 98,203,788 98,306,729 RGD:6480464
G Impad1 inositol monophosphatase domain containing 1 JBrowse link 17 90,191,119 90,218,013 RGD:6480464
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 JBrowse link 3 41,019,898 41,181,070 RGD:6480464
G Kcnu1 potassium calcium-activated channel subfamily U member 1 JBrowse link 16 70,913,825 70,998,593 RGD:6480464
G Keap1 Kelch-like ECH-associated protein 1 JBrowse link 8 22,250,518 22,259,868 RGD:6480464
G Lama4 laminin subunit alpha 4 JBrowse link 20 44,060,715 44,201,966 RGD:6480464
G Lmx1a LIM homeobox transcription factor 1 alpha JBrowse link 13 85,916,753 86,061,534 RGD:6480464
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 JBrowse link 4 10,995,241 12,472,423 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mctp1 multiple C2 and transmembrane domain containing 1 JBrowse link 2 3,400,883 4,089,949 RGD:6480464
G Mfsd4a major facilitator superfamily domain containing 4A JBrowse link 13 48,807,720 48,848,997 RGD:6480464
G MGC95208 similar to 4930453N24Rik protein JBrowse link 11 1,814,294 1,818,942 RGD:6480464
G Mir135a microRNA 135a JBrowse link 7 32,894,877 32,894,976 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480464
G Mtus2 microtubule associated scaffold protein 2 JBrowse link 12 8,111,655 8,491,553 RGD:6480464
G Neb nebulin JBrowse link 3 37,658,081 37,855,843 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nhlrc3 NHL repeat containing 3 JBrowse link 2 142,672,188 142,686,593 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 17 32,131,847 32,158,559 RGD:6480464
G Pcbd2 pterin-4 alpha-carbinolamine dehydratase 2 JBrowse link 17 8,929,675 8,980,712 RGD:6480464
G Pvt1 Pvt1 oncogene JBrowse link 7 102,648,394 102,871,316 RGD:6480464
G Rab3il1 RAB3A interacting protein-like 1 JBrowse link 1 226,077,182 226,084,830 RGD:6480464
G Rap1gap2 RAP1 GTPase activating protein 2 JBrowse link 10 61,177,936 61,395,856 RGD:6480464
G Slc39a11 solute carrier family 39, member 11 JBrowse link 10 101,754,842 102,169,100 RGD:6480464
G Slit2 slit guidance ligand 2 JBrowse link 14 66,831,848 67,171,491 RGD:6480464
G Snx16 sorting nexin 16 JBrowse link 2 93,518,796 93,541,056 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Spag16 sperm associated antigen 16 JBrowse link 9 77,027,626 77,833,476 RGD:6480464
G Stab1 stabilin 1 JBrowse link 16 7,220,434 7,250,934 RGD:6480464
G Syne3 spectrin repeat containing, nuclear envelope family member 3 JBrowse link 6 128,639,036 128,716,061 RGD:6480464
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:6480464
G Tmprss2 transmembrane serine protease 2 JBrowse link 11 38,063,914 38,103,406 RGD:6480464
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:6480464
G Tpd52l1 TPD52 like 1 JBrowse link 1 28,454,949 28,578,736 RGD:6480464
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 JBrowse link 5 3,783,247 3,836,485 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 7 26,946,124 26,984,400 RGD:6480464
G Ubash3a ubiquitin associated and SH3 domain containing, A JBrowse link 20 9,941,102 9,986,012 RGD:6480464
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 JBrowse link 15 7,402,210 7,928,320 RGD:6480464
G Vwc2 von Willebrand factor C domain containing 2 JBrowse link 14 91,201,141 91,348,219 RGD:6480464
G Wfdc3 WAP four-disulfide core domain 3 JBrowse link 3 161,193,904 161,212,063 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        biochemical role 19133
          cofactor 15860
            1,4-benzoquinone 140
              1,4-benzoquinone imine + 73
              2-prenyl-1,4-benzoquinone 0
              quinhydrone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic group 18340
                              organic divalent group 18330
                                organodiyl group 18330
                                  carbonyl group 18217
                                    carbonyl compound 18217
                                      ketone 15784
                                        cyclic ketone 13093
                                          quinone 8224
                                            benzoquinones 587
                                              1,4-benzoquinones 583
                                                1,4-benzoquinone 140
                                                  1,4-benzoquinone imine + 73
                                                  2-prenyl-1,4-benzoquinone 0
                                                  quinhydrone 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.