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ONTOLOGY REPORT - ANNOTATIONS


Term:lanosterol
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Accession:CHEBI:16521 term browser browse the term
Definition:A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived.
Synonyms:related_synonym: (3beta)-lanosta-8,24-dien-3-ol;   (3beta,5alpha)-4,4,14-trimethylcholesta-8,24-dien-3-ol;   4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol;   Formula=C30H50O;   InChI=1S/C30H50O/c1-20(2)10-9-11-21(3)22-14-18-30(8)24-12-13-25-27(4,5)26(31)16-17-28(25,6)23(24)15-19-29(22,30)7/h10,21-22,25-26,31H,9,11-19H2,1-8H3/t21-,22-,25+,26+,28-,29-,30+/m1/s1;   InChIKey=CAHGCLMLTWQZNJ-BQNIITSRSA-N;   Lanosta-8,24-dien-3beta-ol;   Lanosterin;   SMILES=C[C@H](CCC=C(C)C)[C@H]1CC[C@@]2(C)C3=C(CC[C@]12C)[C@@]1(C)CC[C@H](O)C(C)(C)[C@@H]1CC3
 alt_id: CHEBI:14500;   CHEBI:25011;   CHEBI:43584;   CHEBI:6374
 xref: Beilstein:2226449 "ChemIDplus";   CAS:79-63-0 "ChemIDplus";   CAS:79-63-0 "KEGG COMPOUND";   DrugBank:DB03696;   HMDB:HMDB0001251;   KEGG:C01724;   KNApSAcK:C00003657;   LIPID_MAPS_instance:LMST01010017 "LIPID MAPS"
 xref_mesh: MESH:D007810
 xref: MetaCyc:LANOSTEROL;   PDBeChem:LAN;   PMID:14660793 "Europe PMC";   PMID:16445886 "Europe PMC";   PMID:21818119 "Europe PMC";   PMID:21838962 "Europe PMC";   PMID:22824432 "Europe PMC";   PMID:22933236 "Europe PMC";   PMID:22988818 "Europe PMC";   PMID:24525128 "Europe PMC";   PMID:26069216 "Europe PMC";   PMID:26200341 "Europe PMC";   Reaxys:2226449 "Reaxys";   Wikipedia:Lanosterol


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lanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:6480464
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:6480464
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:6480464
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:6480464
G Marchf6 membrane associated ring-CH-type finger 6 JBrowse link 2 84,533,546 84,608,743 RGD:6480464
14-demethyllanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Msmo1 methylsterol monooxygenase 1 JBrowse link 16 26,859,441 26,875,880 RGD:6480464
24,25-dihydrolanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          metabolite 19106
            eukaryotic metabolite 18748
              plant metabolite 17044
                lanosterol 7
                  14-demethyllanosterol 1
                  24,25-dihydrolanosterol + 2
                  lanosteryl ester + 0
                  pneumocysterol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic polycyclic compound 16028
                                  steroid 12767
                                    hydroxy steroid 12357
                                      3-hydroxy steroid 9982
                                        sterol 408
                                          3beta-sterol 402
                                            lanosterol 7
                                              14-demethyllanosterol 1
                                              24,25-dihydrolanosterol + 2
                                              lanosteryl ester + 0
                                              pneumocysterol 0
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