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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-hydroxy-4-aminobiphenyl
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Accession:CHEBI:16580 term browser browse the term
Definition:A N-substituted amine that is 4-aminobiphenyl substituted by a hydroxy group at the nitrogen atom.
Synonyms:exact_synonym: N-hydroxy-[1,1'-biphenyl]-4-amine
 related_synonym: 4-biphenylhydroxylamine;   4-hydroxyaminobiphenyl;   4-hydroxylaminobiphenyl;   Formula=C12H11NO;   InChI=1S/C12H11NO/c14-13-12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,13-14H;   InChIKey=MYVLYOJYVMLSFA-UHFFFAOYSA-N;   N-1,1'-biphenyl-4-ylhydroxylamine;   N-4-biphenylylhydroxylamine;   SMILES=C1(C2=CC=CC=C2)=CC=C(C=C1)NO
 alt_id: CHEBI:12601;   CHEBI:21736;   CHEBI:7296
 xref: CAS:6810-26-0;   KEGG:C03622
 xref_mesh: MESH:C014593
 xref: PMID:1600616;   PMID:16970317;   PMID:24881456;   PMID:647655;   Reaxys:2639597


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N-hydroxy-4-aminobiphenyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hras HRas proto-oncogene, GTPase multiple interactions ISO [N-hydroxy-4-aminobiphenyl co-treated with Copper] results in increased mutagenesis of HRAS gene CTD PMID:11275476 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Nat2 N-acetyltransferase 2 increases metabolic processing ISO NAT2 protein results in increased metabolism of N-hydroxy-4-aminobiphenyl CTD PMID:16857729 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions
increases sulfation
ISO N-hydroxy-4-aminobiphenyl inhibits the reaction [SULT1A1 protein results in increased sulfation of Estradiol]
SULT1A1 protein results in increased sulfation of N-hydroxy-4-aminobiphenyl
CTD PMID:17433394 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Sult1c2a sulfotransferase family, cytosolic, 1C, member 2a increases sulfation ISO SULT1C2 protein results in increased sulfation of N-hydroxy-4-aminobiphenyl CTD PMID:17433394 NCBI chr 9:4,152,588...4,168,355
Ensembl chr 9:4,152,589...4,168,221
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO [N-hydroxy-4-aminobiphenyl co-treated with Copper] results in increased mutagenesis of TP53 gene CTD PMID:11275476 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

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  CHEBI ontology 19816
    role 19764
      biological role 19764
        aetiopathogenetic role 18960
          carcinogenic agent 18331
            N-hydroxy-4-aminobiphenyl 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    main group molecular entity 19702
                      s-block molecular entity 19461
                        hydrogen molecular entity 19452
                          hydrides 18707
                            inorganic hydride 17430
                              pnictogen hydride 17402
                                nitrogen hydride 17243
                                  azane 16960
                                    ammonia 16959
                                      organic amino compound 16958
                                        primary amino compound 7872
                                          primary amine 5674
                                            primary arylamine 2956
                                              aminobiphenyl 61
                                                biphenyl-4-amine 61
                                                  N-hydroxy-4-aminobiphenyl 5
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