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ONTOLOGY REPORT - ANNOTATIONS


Term:20-hydroxyecdysone
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Accession:CHEBI:16587 term browser browse the term
Definition:An ecdysteroid that is ecdysone substituted by a hydroxy group at position 20.
Synonyms:exact_synonym: (22R)-2beta,3beta,14alpha,20,22,25-hexahydroxy-5beta-cholest-7-en-6-one
 related_synonym: 20-OH ecdysone;   Crustecdysone;   Ecdysterone;   Formula=C27H44O7;   InChI=1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1;   InChIKey=NKDFYOWSKOHCCO-YPVLXUMRSA-N;   SMILES=[H][C@]12CC[C@]3(C)[C@]([H])(CC[C@@]3(O)C1=CC(=O)[C@]1([H])C[C@@H](O)[C@@H](O)C[C@]21C)[C@@](C)(O)[C@H](O)CCC(C)(C)O;   beta-Ecdysone;   beta-Ecdysterone
 alt_id: CHEBI:11661;   CHEBI:1292;   CHEBI:19795;   CHEBI:49387;   CHEBI:57827
 xref: CAS:5289-74-7 "ChemIDplus";   CAS:5289-74-7 "KEGG COMPOUND";   HMDB:HMDB0030180;   KEGG:C02633;   KNApSAcK:C00003654;   LIPID_MAPS_instance:LMST01010209 "LIPID MAPS"
 xref_mesh: MESH:D004441
 xref: MetaCyc:CPD-276;   PDBeChem:20E;   PMID:15609826 "Europe PMC";   PMID:25593010 "Europe PMC";   PMID:8748375 "Europe PMC";   Reaxys:1917578 "Reaxys";   Wikipedia:20-Hydroxyecdysone


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20-hydroxyecdysone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        prohormone 6
          ecdysone 6
            20-hydroxyecdysone 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic polycyclic compound 16027
                                  steroid 12770
                                    hydroxy steroid 12362
                                      3-hydroxy steroid 9989
                                        sterol 409
                                          3beta-sterol 403
                                            ecdysone 6
                                              20-hydroxyecdysone 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.