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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:glyoxylic acid
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Accession:CHEBI:16891 term browser browse the term
Definition:A 2-oxo monocarboxylic acid that is acetic acid bearing an oxo group at the alpha carbon atom.
Synonyms:exact_synonym: oxoacetic acid
 related_synonym: Formula=C2H2O3;   Glyoxalate;   Glyoxalsaeure;   Glyoxylate;   Glyoxylsaeure;   InChI=1S/C2H2O3/c3-1-2(4)5/h1H,(H,4,5);   InChIKey=HHLFWLYXYJOTON-UHFFFAOYSA-N;   SMILES=[H]C(=O)C(O)=O;   alpha-ketoacetic acid;   formylformic acid;   oxalaldehydic acid;   oxoethanoic acid
 alt_id: CHEBI:24421;   CHEBI:42767;   CHEBI:5509
 xref: Beilstein:741891;   CAS:298-12-4;   DrugBank:DB04343;   Gmelin:25752;   HMDB:HMDB0000119;   KEGG:C00048;   KNApSAcK:C00001186
 xref_mesh: MESH:C031150
 xref: MetaCyc:GLYOX;   PDBeChem:GLV;   PMID:11479160;   PMID:16396466;   PMID:22580421;   PMID:23790896;   Reaxys:741891;   Wikipedia:Glyoxylic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:36655


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glyoxylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6pd glucose-6-phosphate dehydrogenase decreases activity EXP glyoxylic acid results in decreased activity of G6PD protein CTD PMID:15144222 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in decreased abundance of glyoxylic acid analog CTD PMID:26820058 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions
increases expression
EXP [glyoxylic acid co-treated with Calcitriol] results in increased expression of SPP1 mRNA
glyoxylic acid results in increased expression of SPP1 protein
CTD PMID:7571189, PMID:8325891 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
phenylglyoxylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO CYP2E1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions ISO EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      application 19393
        solvent 16459
          formic acid 7881
            formyl group 7847
              aldehyde 7847
                aldehydic acid 10
                  glyoxylic acid 5
                    2-aminophenylglyoxylic acid 0
                    3,5-dihydroxyphenylglyoxylic acid 0
                    4-hydroxyphenylglyoxylic acid 0
                    glyoxylate ester + 0
                    phenylglyoxylic acid + 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        carboacyl group 17348
                                          univalent carboacyl group 17348
                                            formyl group 7847
                                              aldehyde 7847
                                                aldehydic acid 10
                                                  glyoxylic acid 5
                                                    2-aminophenylglyoxylic acid 0
                                                    3,5-dihydroxyphenylglyoxylic acid 0
                                                    4-hydroxyphenylglyoxylic acid 0
                                                    glyoxylate ester + 0
                                                    phenylglyoxylic acid + 2
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