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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:11-deoxycorticosterone
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Accession:CHEBI:16973 term browser browse the term
Definition:A mineralocorticoid that is progesterone substituted at position 21 by a hydroxy group.
Synonyms:related_synonym: 21-Hydroxy-4-pregnene-3,20-dione;   21-Hydroxypregn-4-ene-3,20-dione;   21-hydroxyprogesterone;   4-pregnen-21-ol-3,20-dione;   Cortexone;   DESOXYCORTICOSTERONE;   DOC;   Deoxycorticosterone;   Formula=C21H30O3;   InChI=1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1;   InChIKey=ZESRJSPZRDMNHY-YFWFAHHUSA-N;   Kendall's desoxy compound B;   Reichstein's substance Q;   SMILES=[H][C@@]1(CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)C(=O)CO;   desoxycortone
 alt_id: CHEBI:11314;   CHEBI:19123;   CHEBI:39642;   CHEBI:713;   CHEBI:86536
 xref: Beilstein:2062123;   CAS:64-85-7;   Drug_Central:820;   KEGG:C03205;   KEGG:D07792;   LIPID_MAPS_instance:LMST02030087
 xref_mesh: MESH:D003900
 xref: MetaCyc:11-DEOXYCORTICOSTERONE;   PDBeChem:1CA;   PMID:22770225;   Reaxys:2062123;   Wikipedia:Desoxycorticosterone


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11-deoxycorticosterone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
ISO Desoxycorticosterone results in increased expression of ACTA2 mRNA; Desoxycorticosterone results in increased expression of ACTA2 protein
Rotenone inhibits the reaction [Desoxycorticosterone results in increased expression of ACTA2 protein]
CTD PMID:17596522 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Agt angiotensinogen increases activity EXP Desoxycorticosterone results in increased activity of AGT protein CTD PMID:9087624 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases metabolic processing ISO AKR1C18 protein results in increased metabolism of Desoxycorticosterone CTD PMID:17122075 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Ar androgen receptor multiple interactions ISO Desoxycorticosterone binds to and results in increased activity of AR protein mutant form CTD PMID:11956172 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of BAX protein] CTD PMID:22431579 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein]; Atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of BCL2 protein] CTD PMID:22431579 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Cat catalase multiple interactions EXP CAT protein results in increased susceptibility to [tert-Butylhydroperoxide co-treated with Desoxycorticosterone co-treated with tempol] CTD PMID:12646410 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of CCL2 mRNA; [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of CCL2 protein; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of CCL2 protein] CTD PMID:21135038 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Cdh1 cadherin 1 decreases expression
multiple interactions
ISO Desoxycorticosterone results in decreased expression of CDH1 mRNA; Desoxycorticosterone results in decreased expression of CDH1 protein
Rotenone inhibits the reaction [Desoxycorticosterone results in decreased expression of CDH1 protein]
CTD PMID:17596522 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression
multiple interactions
EXP Desoxycorticosterone results in increased expression of CYBA mRNA; Desoxycorticosterone results in increased expression of CYBA protein
[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of CYBA protein
CTD PMID:16271043, PMID:22431579 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 multiple interactions
affects metabolic processing
increases chemical synthesis
EXP
ISO
Plant Extracts inhibits the reaction [Desoxycorticosterone binds to CYP11B1 protein]
CYP11B1 protein affects the metabolism of Desoxycorticosterone
CYP11B1 protein results in increased chemical synthesis of Desoxycorticosterone
CTD PMID:15666820, PMID:16054388, PMID:19900470 NCBI chr 7:116,248,759...116,255,205
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 affects metabolic processing
increases hydroxylation
multiple interactions
ISO CYP11B2 protein affects the metabolism of Desoxycorticosterone
CYP11B2 protein results in increased hydroxylation of Desoxycorticosterone
[CYP11B2 protein results in increased hydroxylation of Desoxycorticosterone] which results in increased chemical synthesis of Corticosterone
CTD PMID:15985365, PMID:21384875 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression
EXP [Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 mRNA; [Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 protein; Clofibrate inhibits the reaction [Desoxycorticosterone results in increased expression of EDN1 protein]; Mibefradil inhibits the reaction [[Sodium Chloride, Dietary co-treated with Desoxycorticosterone] results in increased expression of EDN1 mRNA]
Desoxycorticosterone results in increased expression of EDN1; Desoxycorticosterone results in increased expression of EDN1 protein
CTD PMID:1860718, PMID:8934362, PMID:12600921, PMID:16054168 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A multiple interactions
affects response to substance
EXP [5-(dimethylamino)-N-(3,4-dimethyl-5-isoxazolyl)-1-naphthalenesulfonamide binds to and results in decreased activity of EDNRA protein] inhibits the reaction [Desoxycorticosterone results in increased chemical synthesis of Reactive Oxygen Species]; [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of EDNRA protein
EDNRA protein affects the susceptibility to Desoxycorticosterone
CTD PMID:12600921, PMID:16271043, PMID:22431579 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Egf epidermal growth factor multiple interactions
increases response to substance
EXP 4,5-dianilinophthalimide inhibits the reaction [EGF protein results in increased susceptibility to Desoxycorticosterone]; RTKI cpd inhibits the reaction [EGF protein results in increased susceptibility to Desoxycorticosterone] CTD PMID:11751714 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Ep300 E1A binding protein p300 multiple interactions EXP Desoxycorticosterone promotes the reaction [EP300 protein binds to SULT1A1 promoter]; Desoxycorticosterone promotes the reaction [EP300 protein binds to TAT promoter] CTD PMID:22465009 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Fabp3 fatty acid binding protein 3 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of FABP3 protein; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of FABP3 protein] CTD PMID:21135038 NCBI chr 5:148,528,854...148,535,597
Ensembl chr 5:148,528,725...148,535,565
JBrowse link
G Gas6 growth arrest specific 6 multiple interactions EXP GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of IL6 protein]; GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of TNF protein] CTD PMID:19564549 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of GPX1 protein] CTD PMID:22431579 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of HAVCR1 mRNA CTD PMID:21135038 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of IL1B mRNA CTD PMID:21135038 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
EXP Desoxycorticosterone results in increased expression of IL6 protein
GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of IL6 protein]
CTD PMID:19564549 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of LCN2 mRNA; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of LCN2 mRNA] CTD PMID:21135038 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 affects localization EXP Desoxycorticosterone affects the localization of NCF1 protein CTD PMID:16271043 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Nos3 nitric oxide synthase 3 decreases phosphorylation
multiple interactions
increases expression
EXP Desoxycorticosterone results in decreased phosphorylation of NOS3 protein
NOS3 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein]
Desoxycorticosterone results in increased expression of NOS3 protein
CTD PMID:11834524, PMID:14993198, PMID:16271043 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of NOX1 protein CTD PMID:22431579 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Nppa natriuretic peptide A increases expression EXP Desoxycorticosterone results in increased expression of NPPA protein CTD PMID:2965178 NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases phosphorylation
multiple interactions
decreases expression
ISO
EXP
Desoxycorticosterone results in increased phosphorylation of NR3C1 protein
Desoxycorticosterone promotes the reaction [NR3C1 protein binds to TAT promoter]
Desoxycorticosterone results in decreased expression of NR3C1 mRNA
Desoxycorticosterone binds to and results in increased activity of NR3C1 protein
CTD PMID:8969928, PMID:11956172, PMID:18483179, PMID:22465009 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 decreases expression EXP Desoxycorticosterone results in decreased expression of NR3C2 mRNA CTD PMID:8969928 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions EXP [PDGFA protein binds to PDGFB protein] which results in increased susceptibility to Desoxycorticosterone CTD PMID:11751714 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP [PDGFA protein binds to PDGFB protein] which results in increased susceptibility to Desoxycorticosterone CTD PMID:11751714 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pomc proopiomelanocortin increases abundance ISO POMC protein results in increased abundance of Desoxycorticosterone CTD PMID:3015796 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO PPARA protein affects the susceptibility to [Sodium Chloride, Dietary co-treated with Desoxycorticosterone] CTD PMID:16054168 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Desoxycorticosterone results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Desoxycorticosterone results in increased expression of PTGS2 protein CTD PMID:15834289, PMID:16271043 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of RAC1 protein CTD PMID:22431579 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Ren renin multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of REN protein CTD PMID:11039 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions EXP Desoxycorticosterone inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:9830022 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions EXP Desoxycorticosterone inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium] CTD PMID:9830022 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression
multiple interactions
EXP Desoxycorticosterone results in decreased expression of SOD1 protein
[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD1 protein]; tempol inhibits the reaction [Desoxycorticosterone results in decreased expression of SOD1 protein]
CTD PMID:12646410, PMID:22431579 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression
EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein]; Atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in decreased expression of SOD2 protein]; SOD2 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein]
Desoxycorticosterone results in decreased expression of SOD2 protein
CTD PMID:11834524, PMID:22431579 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of SPP1 mRNA; [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of SPP1 protein; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of SPP1 mRNA] CTD PMID:21135038 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions EXP Desoxycorticosterone promotes the reaction [EP300 protein binds to SULT1A1 promoter] CTD PMID:22465009 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP Desoxycorticosterone promotes the reaction [EP300 protein binds to TAT promoter]; Desoxycorticosterone promotes the reaction [NR3C1 protein binds to TAT promoter] CTD PMID:22465009 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tnc tenascin C multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TNC mRNA; Mineralocorticoid Receptor Antagonists inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TNC mRNA]; Spironolactone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride, Dietary] results in increased expression of TNC mRNA] CTD PMID:21135038 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP GAS6 protein promotes the reaction [Desoxycorticosterone results in increased expression of TNF protein] CTD PMID:19564549 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP [Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein; acetovanillone inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein]; atrasentan inhibits the reaction [[Desoxycorticosterone co-treated with Sodium Chloride] results in increased expression of TP53 protein] CTD PMID:22431579 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions
increases expression
EXP NOS3 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein]; SOD2 protein inhibits the reaction [Desoxycorticosterone results in increased expression of VCAM1 protein] CTD PMID:11834524 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Xdh xanthine dehydrogenase increases activity
multiple interactions
EXP Desoxycorticosterone results in increased activity of XDH protein
Desoxycorticosterone promotes the reaction [XDH protein results in increased chemical synthesis of Reactive Oxygen Species]
CTD PMID:16271043 NCBI chr 6:25,149,570...25,211,273
Ensembl chr 6:25,149,235...25,211,494
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      group 19698
        organic group 18495
          3-oxo-Delta(4)-steroid group 7935
            3-oxo-Delta(4) steroid 7935
              11-deoxycorticosterone 49
                11-deoxycorticosterone-21-hemisuccinate 0
                5beta-dihydrodeoxycorticosterone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      ketone 16144
                                        oxyketone 8631
                                          alpha-oxyketone 8631
                                            alpha-hydroxy ketone 8631
                                              primary alpha-hydroxy ketone 7516
                                                11-deoxycorticosterone 49
                                                  11-deoxycorticosterone-21-hemisuccinate 0
                                                  5beta-dihydrodeoxycorticosterone 0
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