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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-acetylneuraminic acid
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Accession:CHEBI:17012 term browser browse the term
Definition:An N-acylneuraminic acid where the N-acyl group is specified as acetyl.
Synonyms:exact_synonym: 5-acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid
 related_synonym: 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-2-nonulosonic acid;   Aceneuramic acid;   Formula=C11H19NO9;   InChI=1S/C11H19NO9/c1-4(14)12-7-5(15)2-11(20,10(18)19)21-9(7)8(17)6(16)3-13/h5-9,13,15-17,20H,2-3H2,1H3,(H,12,14)(H,18,19)/t5-,6+,7+,8+,9+,11?/m0/s1;   InChIKey=SQVRNKJHWKZAKO-LUWBGTNYSA-N;   Neu5Ac;   NeuAc;   O-sialic acid;   SMILES=[H][C@]1(OC(O)(C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CO;   acide aceneuramique;   acidium aceneuramicum;   acido aceneuramico
 alt_id: CHEBI:21620;   CHEBI:7214
 xref: Beilstein:2951361;   CAS:131-48-6;   GlyTouCan:G81533KY;   KEGG:C00270;   KNApSAcK:C00019584
 xref_mesh: MESH:D019158
 xref: PMID:14960498;   PMID:16209099;   PMID:16624269;   PMID:18487279;   PMID:19329108;   PMID:7508418;   PMID:8448384;   Reaxys:1398688;   Wikipedia:N-acetylneuraminic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:35418


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N-acetylneuraminic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase affects abundance ISO CMAS protein affects the abundance of N-Acetylneuraminic Acid; CMAS protein affects the abundance of N-Acetylneuraminic Acid analog CTD PMID:27380425 NCBI chr 4:176,994,129...177,012,445
Ensembl chr 4:176,994,129...177,012,444
JBrowse link
G Gne glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase increases chemical synthesis EXP GNE protein results in increased chemical synthesis of N-Acetylneuraminic Acid CTD PMID:9305888 NCBI chr 5:59,511,738...59,553,421
Ensembl chr 5:59,512,872...59,553,416
JBrowse link
G Nans N-acetylneuraminate synthase increases chemical synthesis ISO NANS results in increased chemical synthesis of N-Acetylneuraminic Acid CTD PMID:27213289 NCBI chr 5:62,109,352...62,126,492
Ensembl chr 5:62,109,328...62,126,494
JBrowse link
CMP-N-acetyl-beta-neuraminic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmas cytidine monophosphate N-acetylneuraminic acid synthetase affects abundance ISO CMAS protein affects the abundance of Cytidine Monophosphate N-Acetylneuraminic Acid CTD PMID:27380425 NCBI chr 4:176,994,129...177,012,445
Ensembl chr 4:176,994,129...177,012,444
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      chemical role 19250
        antioxidant 14211
          N-acetylneuraminic acid 3
            3-acetamido-3,5-dideoxy-L-lyxo-hept-6-ulopyranosuronic acid 0
            5-acetamido-3,5-dideoxy-L-arabino-hept-2-ulopyranosonic acid 0
            9-deoxy-9-acetamido-N-acetyl-alpha-neuraminic acid 0
            N-acetyl-alpha-neuraminic acid + 0
            N-acetyl-beta-neuraminic acid + 1
            N-acetylneuraminamide + 0
            N-acetylneuraminol + 0
            N-acetylneuraminyl group 0
            beta-D-Galp-(1->9)-Neup5Ac 0
            ethyl N-acetylneuraminate 0
            methyl N-acetylneuraminate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        carbohydrate acid 757
                                          ketoaldonic acid 627
                                            ketoaldonic acid derivative 3
                                              neuraminic acids 3
                                                sialic acid 3
                                                  N-acylneuraminic acid 3
                                                    N-acetylneuraminic acids 3
                                                      N-acetylneuraminic acid 3
                                                        3-acetamido-3,5-dideoxy-L-lyxo-hept-6-ulopyranosuronic acid 0
                                                        5-acetamido-3,5-dideoxy-L-arabino-hept-2-ulopyranosonic acid 0
                                                        9-deoxy-9-acetamido-N-acetyl-alpha-neuraminic acid 0
                                                        N-acetyl-alpha-neuraminic acid + 0
                                                        N-acetyl-beta-neuraminic acid + 1
                                                        N-acetylneuraminamide + 0
                                                        N-acetylneuraminol + 0
                                                        N-acetylneuraminyl group 0
                                                        beta-D-Galp-(1->9)-Neup5Ac 0
                                                        ethyl N-acetylneuraminate 0
                                                        methyl N-acetylneuraminate 0
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