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ONTOLOGY REPORT - ANNOTATIONS


Term:progesterone
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Accession:CHEBI:17026 term browser browse the term
Definition:A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Synonyms:exact_synonym: pregn-4-ene-3,20-dione
 related_synonym: (S)-4-Pregnene-3,20-dione;   (S)-Pregn-4-en-3,20-dione;   (S)-Progesterone;   17alpha-progesterone;   4-Pregnene-3,20-dione;   Agolutin;   Akrolutin;   Crinone;   Delta(4)-pregnene-3,20-dione;   Formula=C21H30O2;   Gelbkoerperhormon;   InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1;   InChIKey=RJKFOVLPORLFTN-LEKSSAKUSA-N;   Progesteron;   SMILES=[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])C(C)=O;   corpus luteum hormone;   luteohormone
 alt_id: CHEBI:14896;   CHEBI:18798;   CHEBI:26269;   CHEBI:439;   CHEBI:45786;   CHEBI:8453
 xref: Beilstein:1915950 "Beilstein";   CAS:57-83-0 "ChemIDplus";   CAS:57-83-0 "KEGG COMPOUND";   CAS:57-83-0 "NIST Chemistry WebBook";   DrugBank:DB00396;   Drug_Central:2279 "DrugCentral";   Gmelin:708590 "Gmelin";   HMDB:HMDB0001830;   KEGG:C00410;   KEGG:D00066
 xref_mesh: MESH:D011374
 xref: MetaCyc:PROGESTERONE;   PDBeChem:STR;   PMID:10438974 "Europe PMC";   PMID:9506942 "Europe PMC";   Reaxys:1915950 "Reaxys";   Wikipedia:Progesterone


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Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    chemical entity 19667
      group 19582
        organic group 18343
          3-oxo-Delta(4)-steroid group 7905
            3-oxo-Delta(4) steroid 7905
              progesterone 2686
                11,21-dioxoprogesterone 0
                11-deoxycorticosterone + 47
                11alpha-hydroxyprogesterone + 0
                11beta-hydroxyprogesterone 0
                12alpha-hydroxyprogesterone 0
                15beta-hydroxyprogesterone 0
                16,17-didehydroprogesterone 0
                16alpha-hydroxyprogesterone 0
                16beta-methylpregn-4-ene-3,20-dione 0
                17alpha-hydroxyprogesterone 10
                2,5-dioxo-1-pyrrolidinyl 6-(6-\{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl\}amino)hexanoate 0
                21-dehydrocortisol 1
                21-dehydrocortisone 0
                3-(progesterone-4-yl)thiopropionic acid 0
                3-(progesterone-7alpha-yl)thiopropionic acid 0
                4-pregnen-3beta,20alpha-diol 0
                4-pregnen-3beta-ol-20-one 0
                5alpha-pregnane-3,20-dione 14
                6-(6-\{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl\}amino)hexanoic acid 0
                6-\{3-[(progesterone-4-yl)thiopropionyl]amino\}hexanoic acid 0
                6beta,16alpha,17alpha-trihydroxyprogesterone 0
                9-fluoro-2alpha-methylpregn-4-ene-3,11,20-trione 0
                Delta(1)-progesterone + 235
                progesterone 3-O-(carboxymethyl)oxime + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      ketone 15789
                                        oxo steroid 9257
                                          3-oxo steroid 8780
                                            3-oxo-Delta(4) steroid 7905
                                              progesterone 2686
                                                11,21-dioxoprogesterone 0
                                                11-deoxycorticosterone + 47
                                                11alpha-hydroxyprogesterone + 0
                                                11beta-hydroxyprogesterone 0
                                                12alpha-hydroxyprogesterone 0
                                                15beta-hydroxyprogesterone 0
                                                16,17-didehydroprogesterone 0
                                                16alpha-hydroxyprogesterone 0
                                                16beta-methylpregn-4-ene-3,20-dione 0
                                                17alpha-hydroxyprogesterone 10
                                                2,5-dioxo-1-pyrrolidinyl 6-(6-\{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl\}amino)hexanoate 0
                                                21-dehydrocortisol 1
                                                21-dehydrocortisone 0
                                                3-(progesterone-4-yl)thiopropionic acid 0
                                                3-(progesterone-7alpha-yl)thiopropionic acid 0
                                                4-pregnen-3beta,20alpha-diol 0
                                                4-pregnen-3beta-ol-20-one 0
                                                5alpha-pregnane-3,20-dione 14
                                                6-(6-\{3-[(progesterone-4-yl)thiopropionyl]aminohexanoyl\}amino)hexanoic acid 0
                                                6-\{3-[(progesterone-4-yl)thiopropionyl]amino\}hexanoic acid 0
                                                6beta,16alpha,17alpha-trihydroxyprogesterone 0
                                                9-fluoro-2alpha-methylpregn-4-ene-3,11,20-trione 0
                                                Delta(1)-progesterone + 235
                                                progesterone 3-O-(carboxymethyl)oxime + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.