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ONTOLOGY REPORT - ANNOTATIONS


Term:biliverdin
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Accession:CHEBI:17033 term browser browse the term
Definition:A linear tetrapyrrole produced in the reticuloendothelial system by the first step of heme degradation, catalysed by heme oxygenase.
Synonyms:related_synonym: 8,12-bis(2-carboxyethyl)-2,7,13,17-tetramethyl-3,18-divinylbilin-1(19)(21H,24H)-dione;   BILIVERDINE IX ALPHA;   Biliverdin IX alpha;   Biliverdin IXalpha;   Biliverdine;   Formula=C33H34N4O6;   InChI=1S/C33H34N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-,28-15-;   InChIKey=QBUVFDKTZJNUPP-BBROENKCSA-N;   SMILES=CC1=C(CCC(O)=O)\\C(/N=C1/C=C1NC(=O)C(C=C)=C/1C)=C\\c1[nH]c(\\C=C2NC(=O)C(C)=C/2C=C)c(C)c1CCC(O)=O
 alt_id: CHEBI:13901;   CHEBI:13902;   CHEBI:22875;   CHEBI:3102;   CHEBI:41124
 xref: Beilstein:74351 "Beilstein";   CAS:114-25-0 "ChemIDplus";   CAS:114-25-0 "KEGG COMPOUND";   DrugBank:DB02073;   HMDB:HMDB0001008;   KEGG:C00500
 xref_mesh: MESH:D001664
 xref: PDBeChem:BLA;   PMID:14977878 "Europe PMC";   PMID:19617398 "Europe PMC";   Reaxys:74351 "Reaxys";   Wikipedia:Biliverdin
 cyclic_relationship: is_conjugate_acid_of CHEBI:57991


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biliverdin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 JBrowse link 1 83,653,248 83,662,118 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          metabolite 19106
            eukaryotic metabolite 18748
              animal metabolite 18486
                mammalian metabolite 18468
                  human metabolite 18127
                    biliverdin 10
                      15,16-dihydrobiliverdin 0
                      biliverdin hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic heterocyclic compound 18157
                                  organonitrogen heterocyclic compound 16961
                                    polypyrrole 590
                                      tetrapyrrole 478
                                        linear tetrapyrrole 169
                                          bilins 10
                                            biliverdin 10
                                              15,16-dihydrobiliverdin 0
                                              biliverdin hydrochloride 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.