Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


go back to main search page
Accession:CHEBI:17076 term browser browse the term
Definition:A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class
Synonyms:exact_synonym: N,N'''-[(1R,2R,3S,4R,5R,6S)-4-{5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyloxy}-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine
 related_synonym: 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside;   Formula=C21H39N7O12;   InChI=1S/C21H39N7O12/c1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35/h4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28)/t5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+/m0/s1;   InChIKey=UCSJYZPVAKXKNQ-HZYVHMACSA-N;   Kantrex;   SM;   SMILES=CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]1[C@@H](O[C@@H](C)[C@]1(O)C=O)O[C@H]1[C@H](O)[C@@H](O)[C@H](NC(N)=N)[C@@H](O)[C@@H]1NC(N)=N;   [2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{N',N'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine};   streomycin
 alt_id: CHEBI:15119;   CHEBI:26784;   CHEBI:45745;   CHEBI:9284
 xref: Beilstein:74498;   CAS:57-92-1;   DrugBank:DB01082;   Drug_Central:2481;   HMDB:HMDB0015214;   KEGG:C00413;   KEGG:D08531
 xref_mesh: MESH:D013307
 xref: MetaCyc:STREPTOMYCIN;   PDBeChem:SRY;   PMID:11228320;   PMID:11905029;   PMID:12118520;   PMID:13030054;   PMID:13116094;   PMID:13136149;   PMID:13596285;   PMID:13691614;   PMID:13985260;   PMID:13990247;   PMID:14623118;   PMID:14828344;   PMID:14852338;   PMID:14939639;   PMID:15081082;   PMID:15137533;   PMID:15207172;   PMID:15686853;   PMID:15736038;   PMID:16904706;   PMID:17105735;   PMID:17238915;   PMID:17429930;   PMID:18173084;   PMID:18916143;   PMID:19052412;   PMID:19335957;   PMID:21350946;   PMID:21362244;   PMID:21593257;   PMID:21937264;   PMID:22101040;   Pesticides:streptomycin;   Reaxys:74498;   Wikipedia:Streptomycin
 cyclic_relationship: is_conjugate_base_of CHEBI:58007

show annotations for term's descendants       view all columns           Sort by:
streptomycin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hoxb9 homeo box B9 JBrowse link 10 84,119,772 84,124,963 RGD:6480464
G Pax3 paired box 3 JBrowse link 9 84,004,004 84,101,226 RGD:6480464
G Tcf15 transcription factor 15 JBrowse link 3 147,643,250 147,649,511 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Uncx UNC homeobox JBrowse link 12 17,182,158 17,186,679 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      biological role 19716
        antimicrobial agent 17275
          streptomycin 5
            3''-adenylylstreptomycin 0
            5'-hydroxystreptomycin 0
            streptomycin sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19653
                    p-block element atom 19653
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            heteroorganic entity 19121
                              organochalcogen compound 18824
                                organooxygen compound 18738
                                  carbohydrates and carbohydrate derivatives 12127
                                    carbohydrate 12127
                                      carbohydrate derivative 11752
                                        glycosyl compound 10808
                                          glycoside 9153
                                            aminoglycoside 8366
                                              aminoglycoside antibiotic 2533
                                                streptomycins 5
                                                  streptomycin 5
                                                    3''-adenylylstreptomycin 0
                                                    5'-hydroxystreptomycin 0
                                                    streptomycin sulfate 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.