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ONTOLOGY REPORT - ANNOTATIONS


Term:cysteamine
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Accession:CHEBI:17141 term browser browse the term
Definition:An amine that consists of an ethane skeleton substituted with a thiol group at C-1 and an amino group at C-2.
Synonyms:related_synonym: 2-AMINO-ETHANETHIOL;   2-Aminoethanethiol;   2-amino-1-ethanethiol;   Formula=C2H7NS;   InChI=1S/C2H7NS/c3-1-2-4/h4H,1-3H2;   InChIKey=UFULAYFCSOUIOV-UHFFFAOYSA-N;   MEA;   SMILES=NCCS;   Thioethanolamine;   beta-Aminoethanethiol;   beta-MEA;   beta-Mercaptoethylamine;   beta-aminoethylthiol;   mercaptamina;   mercaptamine;   mercaptaminum
 alt_id: CHEBI:14060;   CHEBI:15235;   CHEBI:23506;   CHEBI:4049;   CHEBI:41923
 xref: Beilstein:635649 "Beilstein";   CAS:60-23-1 "ChemIDplus";   CAS:60-23-1 "KEGG COMPOUND";   CAS:60-23-1 "NIST Chemistry WebBook";   DrugBank:DB00847;   Drug_Central:768 "DrugCentral";   Gmelin:25385 "Gmelin";   HMDB:HMDB0002991;   KEGG:C01678;   KEGG:D03634
 xref_mesh: MESH:D003543
 xref: MetaCyc:CPD-239;   PDBeChem:DHL;   PMID:17581819 "Europe PMC";   PMID:22735334 "Europe PMC";   Reaxys:635649 "Reaxys";   Wikipedia:Cysteamine
 cyclic_relationship: is_conjugate_base_of CHEBI:58029


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cysteamine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctsd cathepsin D JBrowse link 1 215,541,570 215,553,446 RGD:6480464
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 JBrowse link 5 19,358,734 19,368,431 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Mmp12 matrix metallopeptidase 12 JBrowse link 8 5,594,717 5,616,494 RGD:6480464
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sst somatostatin JBrowse link 11 80,358,172 80,359,449 RGD:6480464
G Vnn1 vanin 1 JBrowse link 1 22,614,832 22,625,134 RGD:6480464
amifostine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Ei24 EI24, autophagy associated transmembrane protein JBrowse link 8 39,254,883 39,271,238 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6480464
G Mdm2 MDM2 proto-oncogene JBrowse link 7 60,719,060 60,743,618 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Myl2 myosin light chain 2 JBrowse link 12 39,951,863 39,959,065 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tp53i3 tumor protein p53 inducible protein 3 JBrowse link 13 75,101,759 75,145,967 RGD:6480464
cystamine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Tgm2 transglutaminase 2 JBrowse link 3 154,597,165 154,627,257 RGD:6480464
G Timp1 TIMP metallopeptidase inhibitor 1 JBrowse link X 1,364,771 1,369,451 RGD:6480464
N-acetylcysteamine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:6480464
G Erbb2 erb-b2 receptor tyrosine kinase 2 JBrowse link 10 86,367,596 86,391,728 RGD:6480464
G Erbb3 erb-b2 receptor tyrosine kinase 3 JBrowse link 7 2,989,202 3,010,610 RGD:6480464
WR-1065 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl5 C-C motif chemokine ligand 5 JBrowse link 10 70,739,764 70,744,303 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Il2ra interleukin 2 receptor subunit alpha JBrowse link 17 70,500,672 70,547,929 RGD:6480464
G Myb MYB proto-oncogene, transcription factor JBrowse link 1 16,658,178 16,690,135 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Tnfrsf1a TNF receptor superfamily member 1A JBrowse link 4 157,864,905 157,877,634 RGD:6480464
G Tnfrsf1b TNF receptor superfamily member 1B JBrowse link 5 163,136,390 163,167,299 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    chemical entity 19660
      group 19576
        inorganic group 19019
          thiol group 1919
            thiol 1919
              cysteamine 43
                N-acetylcysteamine 3
                S-acetylcysteamine 0
                WR-1065 11
                amifostine 17
                cystamine 4
                cysteamine S-phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    main group molecular entity 19539
                      s-block molecular entity 19322
                        hydrogen molecular entity 19312
                          hydrides 18241
                            inorganic hydride 17110
                              pnictogen hydride 17068
                                nitrogen hydride 16889
                                  azane 16565
                                    ammonia 16562
                                      organic amino compound 16561
                                        primary amino compound 6641
                                          primary amine 4138
                                            primary aliphatic amine 133
                                              ethylamine 44
                                                cysteamine 43
                                                  N-acetylcysteamine 3
                                                  S-acetylcysteamine 0
                                                  WR-1065 11
                                                  amifostine 17
                                                  cystamine 4
                                                  cysteamine S-phosphate 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.