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ONTOLOGY REPORT - ANNOTATIONS


Term:methylglyoxal
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Accession:CHEBI:17158 term browser browse the term
Definition:A 2-oxo aldehyde derived from propanal.
Synonyms:related_synonym: 1,2-propanedione;   2-Ketopropionaldehyde;   2-Oxopropanal;   2-oxopropionaldehyde;   CH3COCHO;   Formula=C3H4O2;   InChI=1S/C3H4O2/c1-3(5)2-4/h2H,1H3;   InChIKey=AIJULSRZWUXGPQ-UHFFFAOYSA-N;   Pyruvaldehyde;   Pyruvic aldehyde;   SMILES=[H]C(=O)C(C)=O;   acetylformaldehyde;   acetylformyl;   alpha-ketopropionaldehyde
 alt_id: CHEBI:11643;   CHEBI:14599;   CHEBI:25303;   CHEBI:6875
 xref: Beilstein:906750 "Beilstein";   CAS:78-98-8 "ChemIDplus";   CAS:78-98-8 "KEGG COMPOUND";   CAS:78-98-8 "NIST Chemistry WebBook";   KEGG:C00546;   KNApSAcK:C00007562
 xref_mesh: MESH:D011765
 xref: PMID:10373458 "Europe PMC";   PMID:10723098 "Europe PMC";   PMID:11504881 "Europe PMC";   PMID:15520007 "Europe PMC";   PMID:17103372 "Europe PMC";   PMID:19202315 "Europe PMC";   PMID:20096340 "Europe PMC";   PMID:22983866 "Europe PMC";   PMID:23543734 "Europe PMC";   PMID:23845007 "Europe PMC";   PMID:24040205 "Europe PMC";   PMID:24168114 "Europe PMC";   PMID:26861824 "Europe PMC";   PMID:9506998 "Europe PMC";   Reaxys:906750 "Reaxys";   Wikipedia:Methylglyoxal


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methylglyoxal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACP5 acid phosphatase 5, tartrate resistant JBrowse link 19 11,574,660 11,578,983 RGD:6480464
G ACTA2 actin alpha 2, smooth muscle JBrowse link 10 88,935,074 88,991,397 RGD:6480464
G ADGRE1 adhesion G protein-coupled receptor E1 JBrowse link 19 6,887,549 6,940,450 RGD:6480464
G AGER advanced glycosylation end-product specific receptor JBrowse link 6 32,180,968 32,184,380 RGD:6480464
G AGT angiotensinogen JBrowse link 1 230,702,523 230,714,122 RGD:6480464
G AIFM2 apoptosis inducing factor mitochondria associated 2 JBrowse link 10 70,112,267 70,132,934 RGD:6480464
G AKR1A1 aldo-keto reductase family 1 member A1 JBrowse link 1 45,550,779 45,570,051 RGD:6480464
G AKR1B1 aldo-keto reductase family 1 member B JBrowse link 7 134,442,350 134,459,239 RGD:6480464
G AKR1C3 aldo-keto reductase family 1 member C3 JBrowse link 10 5,048,766 5,107,686 RGD:6480464
G AKR7A2 aldo-keto reductase family 7 member A2 JBrowse link 1 19,302,708 19,312,146 RGD:6480464
G AKT1 AKT serine/threonine kinase 1 JBrowse link 14 104,769,349 104,795,748 RGD:6480464
G AKT2 AKT serine/threonine kinase 2 JBrowse link 19 40,230,317 40,285,531 RGD:6480464
G ALB albumin JBrowse link 4 73,404,287 73,421,482 RGD:6480464
G ALDH2 aldehyde dehydrogenase 2 family member JBrowse link 12 111,766,933 111,817,532 RGD:6480464
G BAD BCL2 associated agonist of cell death JBrowse link 11 64,269,828 64,284,704 RGD:6480464
G BAX BCL2 associated X, apoptosis regulator JBrowse link 19 48,954,825 48,961,798 RGD:6480464
G BCL2 BCL2 apoptosis regulator JBrowse link 18 63,123,346 63,320,280 RGD:6480464
G BDNF brain derived neurotrophic factor JBrowse link 11 27,654,893 27,722,030 RGD:6480464
G CA2 carbonic anhydrase 2 JBrowse link 8 85,463,902 85,481,493 RGD:6480464
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:6480464
G CASP9 caspase 9 JBrowse link 1 15,491,401 15,524,912 RGD:6480464
G CCL2 C-C motif chemokine ligand 2 JBrowse link 17 34,255,285 34,257,203 RGD:6480464
G CLCN7 chloride voltage-gated channel 7 JBrowse link 16 1,444,933 1,475,084 RGD:6480464
G COL3A1 collagen type III alpha 1 chain JBrowse link 2 188,974,373 189,012,746 RGD:6480464
G CP ceruloplasmin JBrowse link 3 149,162,410 149,222,008 RGD:6480464
G CTSK cathepsin K JBrowse link 1 150,796,208 150,808,260 RGD:6480464
G CTSS cathepsin S JBrowse link 1 150,730,188 150,765,778 RGD:6480464
G CXCL8 C-X-C motif chemokine ligand 8 JBrowse link 4 73,740,569 73,743,716 RGD:6480464
G FN1 fibronectin 1 JBrowse link 2 215,360,440 215,436,167 RGD:6480464
G FOS Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 14 75,278,828 75,282,230 RGD:6480464
G GAB2 GRB2 associated binding protein 2 JBrowse link 11 78,215,290 78,417,820 RGD:6480464
G GLO1 glyoxalase I JBrowse link 6 38,675,925 38,703,145 RGD:6480464
G GPX1 glutathione peroxidase 1 JBrowse link 3 49,357,171 49,358,600 RGD:6480464
G GSR glutathione-disulfide reductase JBrowse link 8 30,678,061 30,727,999 RGD:6480464
G GSTA5 glutathione S-transferase alpha 5 JBrowse link 6 52,831,742 52,846,095 RGD:6480464
G HIF1A hypoxia inducible factor 1 subunit alpha JBrowse link 14 61,695,513 61,748,259 RGD:6480464
G HMOX1 heme oxygenase 1 JBrowse link 22 35,381,096 35,394,207 RGD:6480464
G HRAS HRas proto-oncogene, GTPase JBrowse link 11 532,242 535,576 RGD:6480464
G HSPB1 heat shock protein family B (small) member 1 JBrowse link 7 76,302,673 76,304,292 RGD:6480464
G IL1B interleukin 1 beta JBrowse link 2 112,829,751 112,836,843 RGD:6480464
G IL6 interleukin 6 JBrowse link 7 22,725,889 22,732,002 RGD:6480464
G INS insulin JBrowse link 11 2,159,779 2,161,209 RGD:6480464
G INSR insulin receptor JBrowse link 19 7,112,257 7,294,414 RGD:6480464
G IRS1 insulin receptor substrate 1 JBrowse link 2 226,731,317 226,798,790 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G MAPK8 mitogen-activated protein kinase 8 JBrowse link 10 48,306,639 48,439,360 RGD:6480464
G MAPK9 mitogen-activated protein kinase 9 JBrowse link 5 180,233,143 180,292,083 RGD:6480464
G MAPT microtubule associated protein tau JBrowse link 17 45,894,382 46,028,334 RGD:6480464
G MMP9 matrix metallopeptidase 9 JBrowse link 20 46,008,908 46,016,561 RGD:6480464
G NFATC1 nuclear factor of activated T cells 1 JBrowse link 18 79,395,930 79,529,323 RGD:6480464
G NFE2L2 nuclear factor, erythroid 2 like 2 JBrowse link 2 177,230,303 177,265,131 RGD:6480464
G NOS2 nitric oxide synthase 2 JBrowse link 17 27,756,766 27,800,529 RGD:6480464
G NQO1 NAD(P)H quinone dehydrogenase 1 JBrowse link 16 69,709,401 69,726,560 RGD:6480464
G NRF1 nuclear respiratory factor 1 JBrowse link 7 129,611,720 129,757,082 RGD:6480464
G NTRK2 neurotrophic receptor tyrosine kinase 2 JBrowse link 9 84,668,458 85,027,070 RGD:6480464
G OSCAR osteoclast associated Ig-like receptor JBrowse link 19 54,094,668 54,102,686 RGD:6480464
G OSTM1 osteoclastogenesis associated transmembrane protein 1 JBrowse link 6 108,041,409 108,074,741 RGD:6480464
G PARP1 poly(ADP-ribose) polymerase 1 JBrowse link 1 226,360,691 226,408,093 RGD:6480464
G PDX1 pancreatic and duodenal homeobox 1 JBrowse link 13 27,919,982 27,926,313 RGD:6480464
G PECAM1 platelet and endothelial cell adhesion molecule 1 JBrowse link 17 64,319,415 64,413,844 RGD:6480464
G PON1 paraoxonase 1 JBrowse link 7 95,297,676 95,324,532 RGD:6480464
G PPARG peroxisome proliferator activated receptor gamma JBrowse link 3 12,287,485 12,434,344 RGD:6480464
G PPARGC1A PPARG coactivator 1 alpha JBrowse link 4 23,792,021 24,472,905 RGD:6480464
G PTPN1 protein tyrosine phosphatase non-receptor type 1 JBrowse link 20 50,510,321 50,585,241 RGD:6480464
G RELA RELA proto-oncogene, NF-kB subunit JBrowse link 11 65,653,596 65,662,972 RGD:6480464
G SIRT1 sirtuin 1 JBrowse link 10 67,884,656 67,918,390 RGD:6480464
G SLC2A2 solute carrier family 2 member 2 JBrowse link 3 170,996,341 171,026,721 RGD:6480464
G SOD1 superoxide dismutase 1 JBrowse link 21 31,659,693 31,668,931 RGD:6480464
G SOD2 superoxide dismutase 2 JBrowse link 6 159,669,069 159,762,281 RGD:6480464
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 JBrowse link 11 68,039,000 68,053,846 RGD:6480464
G TGFB1 transforming growth factor beta 1 JBrowse link 19 41,330,323 41,353,922 RGD:6480464
G TNF tumor necrosis factor JBrowse link 6 31,575,565 31,578,336 RGD:6480464
G TNFSF11 TNF superfamily member 11 JBrowse link 13 42,562,736 42,608,013 RGD:6480464
G TRAF6 TNF receptor associated factor 6 JBrowse link 11 36,483,769 36,510,313 RGD:6480464
G TRPA1 transient receptor potential cation channel subfamily A member 1 JBrowse link 8 72,021,250 72,094,885 RGD:6480464
G VCAM1 vascular cell adhesion molecule 1 JBrowse link 1 100,719,640 100,739,045 RGD:6480464
G VEGFA vascular endothelial growth factor A JBrowse link 6 43,770,209 43,786,487 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23754
    role 23643
      application 23039
        solvent 17488
          formic acid 8661
            formyl group 8628
              aldehyde 8628
                propanals 2095
                  methylglyoxal 78
                    mitoguazone 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23754
    subatomic particle 23703
      composite particle 23703
        hadron 23703
          baryon 23703
            nucleon 23703
              atomic nucleus 23703
                atom 23703
                  main group element atom 23522
                    p-block element atom 23522
                      carbon group element atom 23232
                        carbon atom 23208
                          organic molecular entity 23208
                            organic group 21897
                              organic divalent group 21869
                                organodiyl group 21869
                                  carbonyl group 21840
                                    carbonyl compound 21840
                                      carboxylic acid 20885
                                        carboacyl group 18982
                                          univalent carboacyl group 18982
                                            formyl group 8628
                                              aldehyde 8628
                                                ketoaldehyde 78
                                                  2-oxo aldehyde 78
                                                    methylglyoxal 78
                                                      mitoguazone 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.