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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:UDP-alpha-D-glucuronic acid
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Accession:CHEBI:17200 term browser browse the term
Definition:A UDP-sugar having alpha-D-glucuronic acid as the sugar component.
Synonyms:exact_synonym: uridine 5'-[3-(alpha-D-glucopyranuronosyl) dihydrogen diphosphate]
 related_synonym: Formula=C15H22N2O18P2;   InChI=1S/C15H22N2O18P2/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26)/t4-,6-,7+,8+,9-,10-,11+,12-,14-/m1/s1;   InChIKey=HDYANYHVCAPMJV-LXQIFKJMSA-N;   SMILES=O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)O[C@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)O[C@H]([C@@H]1O)n1ccc(=O)[nH]c1=O;   UDP-D-glucuronate;   UDP-alpha-D-glucuronate;   UDP-glucuronate;   UDPglucuronate;   URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID;   uridine diphosphate glucuronic acid
 alt_id: CHEBI:13489;   CHEBI:13506;   CHEBI:22104;   CHEBI:46309;   CHEBI:9846
 xref: Beilstein:78881;   CAS:2616-64-0;   HMDB:HMDB0000935;   KEGG:C00167;   KEGG:G10612;   KNApSAcK:C00007238
 xref_mesh: MESH:D014535
 xref: PDBeChem:UGA;   PMID:11420884;   PMID:13984680;   PMID:14351193;   Reaxys:78881;   Wikipedia:Uridine_diphosphate_glucuronic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:58052


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UDP-alpha-D-glucuronic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3gat3 beta-1,3-glucuronyltransferase 3 affects binding
multiple interactions
ISO B3GAT3 protein binds to Uridine Diphosphate Glucuronic Acid
Uridine Diphosphate Glucuronic Acid inhibits the reaction [Diacetyl results in decreased activity of B3GAT3 protein]
CTD PMID:11986319 NCBI chr 1:225,120,061...225,126,579
Ensembl chr 1:225,120,061...225,126,579
JBrowse link
G Gale UDP-galactose-4-epimerase affects binding ISO Uridine Diphosphate Glucuronic Acid binds to GALE protein CTD PMID:25526675 NCBI chr 5:154,310,453...154,314,959
Ensembl chr 5:154,310,453...154,314,955
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Uridine Diphosphate Glucuronic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 multiple interactions ISO [Uridine Diphosphate Glucuronic Acid co-treated with UGT1A1 protein] results in increased glucuronidation of Labetalol CTD PMID:18098064 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 multiple interactions ISO [Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased glucuronidation of Labetalol; Fluconazole inhibits the reaction [[Uridine Diphosphate Glucuronic Acid co-treated with UGT2B7 protein] results in increased glucuronidation of Labetalol] CTD PMID:18098064 NCBI chr14:22,597,103...22,619,968 JBrowse link
G Uxs1 UDP-glucuronate decarboxylase 1 multiple interactions ISO [Uridine Diphosphate Glucuronic Acid co-treated with NAD] binds to UXS1 protein CTD PMID:25526675 NCBI chr 9:11,165,006...11,240,329
Ensembl chr 9:11,164,715...11,339,790
JBrowse link

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Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        biochemical role 19313
          metabolite 19294
            prokaryotic metabolite 18402
              bacterial metabolite 18402
                Escherichia coli metabolite 18283
                  UDP-alpha-D-glucuronic acid 6
                    UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      chalcogen 19399
                        oxygen atom 19361
                          oxygen molecular entity 19361
                            hydroxides 19107
                              oxoacid 18241
                                pnictogen oxoacid 10179
                                  phosphorus oxoacid 9071
                                    phosphoric acids 7830
                                      phosphoric acid 7830
                                        phosphoric acid derivative 7511
                                          phosphate 7511
                                            organic phosphate 7510
                                              carbohydrate phosphate 1536
                                                phospho sugar 1462
                                                  aldose phosphate 1460
                                                    aldopentose phosphate 1454
                                                      ribose phosphate 1448
                                                        ribonucleotide 1409
                                                          ribonucleoside 5'-phosphate 412
                                                            ribonucleoside 5'-diphosphate 107
                                                              pyrimidine ribonucleoside 5'-diphosphate 19
                                                                UDP 14
                                                                  UDP-sugar 8
                                                                    UDP-alpha-D-glucuronic acid 6
                                                                      UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 0
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