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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cytidine
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Accession:CHEBI:17562 term browser browse the term
Definition:A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N(1)-glycosidic bond.
Synonyms:related_synonym: 1-beta-D-Ribofuranosylcytosine;   1beta-D-ribofuranosylcytosine;   4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE;   4-amino-1-beta-D-ribofuranosylpyrimidin-2(1H)-one;   4-amino-1beta-D-ribofuranosyl-2(1H)-pyrimidinone;   Cyd;   Cytidin;   Cytosine riboside;   Formula=C9H13N3O5;   InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1;   InChIKey=UHDGCWIWMRVCDJ-XVFCMESISA-N;   SMILES=Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)n1;   Zytidin;   cytosine-1beta-D-Ribofuranoside
 alt_id: CHEBI:14063;   CHEBI:23515;   CHEBI:4053;   CHEBI:41649;   CHEBI:41686;   CHEBI:41704
 xref: Beilstein:89173;   CAS:65-46-3;   DrugBank:DB02097;   Gmelin:84763;   HMDB:HMDB0000089;   KEGG:C00475;   KEGG:D07769
 xref_mesh: MESH:D003562
 xref: MetaCyc:CYTIDINE;   PDBeChem:CTN;   PMID:12591866;   PMID:15621516;   PMID:19194376;   Reaxys:89173;   Wikipedia:Cytidine


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cytidine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor increases activity EXP Cytidine results in increased activity of ADORA1 protein CTD PMID:18313046 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor increases activity EXP Cytidine results in increased activity of ADORA2A protein CTD PMID:18313046 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Chlorine binds to Cytidine] which results in decreased expression of CCL5 mRNA CTD PMID:31066272 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases abundance
multiple interactions
ISO IDH2 protein mutant form results in increased abundance of Cytidine
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Cytidine]
CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Chlorine binds to Cytidine] which results in increased expression of IL1B mRNA; [Chlorine binds to Cytidine] which results in increased expression of IL1B protein CTD PMID:31066272 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Slc28a1 solute carrier family 28 member 1 multiple interactions
increases transport
ISO Cytidine inhibits the reaction [SLC28A1 protein results in increased uptake of Uridine]
SLC28A1 protein results in increased transport of Cytidine
CTD PMID:9124315, PMID:10772724 NCBI chr 1:142,948,942...142,992,410
Ensembl chr 1:142,950,540...142,992,615
JBrowse link
G Slc29a1 solute carrier family 29 member 1 multiple interactions ISO
EXP
Cytidine inhibits the reaction [SLC29A1 protein results in increased uptake of Uridine] CTD PMID:9353301, PMID:11085929 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005
JBrowse link
G Slc29a2 solute carrier family 29 member 2 multiple interactions ISO Cytidine inhibits the reaction [SLC29A2 protein results in increased uptake of Uridine] CTD PMID:11085929 NCBI chr 1:220,306,622...220,314,631
Ensembl chr 1:220,400,855...220,407,189
Ensembl chr 1:220,400,855...220,407,189
JBrowse link
G Upp1 uridine phosphorylase 1 increases metabolic processing ISO UPP1 protein results in increased metabolism of Cytidine CTD PMID:15772079 NCBI chr14:89,314,234...89,334,060
Ensembl chr14:89,314,176...89,334,276
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        biochemical role 19313
          metabolite 19294
            eukaryotic metabolite 18943
              fungal metabolite 17421
                Saccharomyces cerevisiae metabolite 16485
                  cytidine 9
                    cytidine residue 0
                    ddhC 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            heteroorganic entity 19184
                              organochalcogen compound 18894
                                organooxygen compound 18816
                                  carbohydrates and carbohydrate derivatives 12191
                                    carbohydrate 12191
                                      carbohydrate derivative 11814
                                        glycosyl compound 10856
                                          N-glycosyl compound 5340
                                            nucleoside 5200
                                              ribonucleoside 699
                                                pyrimidine ribonucleosides 145
                                                  cytidines 66
                                                    cytidine 9
                                                      cytidine residue 0
                                                      ddhC 0
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