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ONTOLOGY REPORT - ANNOTATIONS


Term:biochanin A
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Accession:CHEBI:17574 term browser browse the term
Definition:A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone which is substituted by an additional hydroxy group at position 5 and a methoxy group at position 4'. A phytoestrogen, it has putative benefits in dietary cancer prophylaxis.
Synonyms:exact_synonym: 5,7-dihydroxy-3-(4-methoxyphenyl)-4H-chromen-4-one
 related_synonym: 4'-methylgenistein;   5,7-dihydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one;   5,7-dihydroxy-3-p-methoxyphenyl-4H-chromen-4-one;   5,7-dihydroxy-4'-methoxyisoflavone;   Formula=C16H12O5;   InChI=1S/C16H12O5/c1-20-11-4-2-9(3-5-11)12-8-21-14-7-10(17)6-13(18)15(14)16(12)19/h2-8,17-18H,1H3;   InChIKey=WUADCCWRTIWANL-UHFFFAOYSA-N;   SMILES=COc1ccc(cc1)-c1coc2cc(O)cc(O)c2c1=O;   olmelin;   pratensol
 alt_id: CHEBI:13903;   CHEBI:22876;   CHEBI:3105
 xref: Beilstein:278107 "Beilstein";   CAS:491-80-5 "ChemIDplus";   CAS:491-80-5 "KEGG COMPOUND";   HMDB:HMDB0002338;   KEGG:C00814;   KNApSAcK:C00002510;   LIPID_MAPS_instance:LMPK12050229 "LIPID MAPS"
 xref_mesh: MESH:C004541
 xref: MetaCyc:BIOCHANIN-A;   PDBeChem:QSO;   PMID:11348577 "Europe PMC";   PMID:11931850 "Europe PMC";   PMID:15277096 "Europe PMC";   PMID:18060767 "Europe PMC";   PMID:20590565 "Europe PMC";   PMID:23406166 "Europe PMC";   PMID:23649249 "Europe PMC";   PMID:23948065 "Europe PMC";   PMID:24129051 "Europe PMC";   PMID:24201306 "Europe PMC";   PMID:28166217 "Europe PMC";   PMID:8947298 "Europe PMC";   Reaxys:278107 "Reaxys";   Wikipedia:Biochanin_A
 cyclic_relationship: is_conjugate_acid_of CHEBI:58194


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biochanin A term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc1 ATP binding cassette subfamily C member 1 JBrowse link 10 549,537 672,235 RGD:6480464
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Agrn agrin JBrowse link 5 173,589,910 173,622,813 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Aldh7a1 aldehyde dehydrogenase 7 family, member A1 JBrowse link 18 51,619,007 51,651,267 RGD:6480464
G Arid5b AT-rich interaction domain 5B JBrowse link 20 21,713,900 21,881,193 RGD:6480464
G Babam2 BRISC and BRCA1 A complex member 2 JBrowse link 6 25,666,654 26,135,888 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Cdh2 cadherin 2 JBrowse link 18 8,146,971 8,366,037 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Ckb creatine kinase B JBrowse link 6 136,142,956 136,145,838 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 JBrowse link 7 70,333,150 70,340,006 RGD:6480464
G Dera deoxyribose-phosphate aldolase JBrowse link 4 171,748,254 171,826,414 RGD:6480464
G Eif5 eukaryotic translation initiation factor 5 JBrowse link 6 136,002,983 136,011,409 RGD:6480464
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 JBrowse link 9 19,469,276 19,476,684 RGD:6480464
G Eps15 epidermal growth factor receptor pathway substrate 15 JBrowse link 5 128,923,809 129,022,268 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:6480464
G Esrra estrogen related receptor, alpha JBrowse link 1 222,168,729 222,178,842 RGD:6480464
G Esrrb estrogen-related receptor beta JBrowse link 6 110,360,940 110,458,406 RGD:6480464
G Esrrg estrogen-related receptor gamma JBrowse link 13 106,063,799 106,683,353 RGD:6480464
G Fbl fibrillarin JBrowse link 1 85,103,519 85,112,619 RGD:6480464
G Folr1 folate receptor alpha JBrowse link 1 166,934,457 166,945,864 RGD:6480464
G Gm2a GM2 ganglioside activator JBrowse link 10 40,438,394 40,450,927 RGD:6480464
G Gnai3 G protein subunit alpha i3 JBrowse link 2 210,896,779 210,934,733 RGD:6480464
G Gpx1 glutathione peroxidase 1 JBrowse link 8 117,117,430 117,118,528 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Il17a interleukin 17A JBrowse link 9 26,841,299 26,844,786 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Lck LCK proto-oncogene, Src family tyrosine kinase JBrowse link 5 147,750,976 147,779,627 RGD:6480464
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 JBrowse link 18 63,717,423 64,045,224 RGD:6480464
G Lxn latexin JBrowse link 2 164,628,565 164,634,434 RGD:6480464
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mt2A metallothionein 2A JBrowse link 19 11,307,966 11,308,740 RGD:6480464
G Ncoa1 nuclear receptor coactivator 1 JBrowse link 6 28,677,563 28,931,844 RGD:6480464
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 JBrowse link 4 51,590,413 51,598,771 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Nono non-POU domain containing, octamer-binding JBrowse link X 71,324,365 71,342,225 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:6480464
G Pfdn5 prefoldin subunit 5 JBrowse link 7 143,924,662 143,929,400 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Plaur plasminogen activator, urokinase receptor JBrowse link 1 81,328,171 81,344,954 RGD:6480464
G Pnrc1 proline-rich nuclear receptor coactivator 1 JBrowse link 5 48,501,472 48,504,511 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rabl6 RAB, member RAS oncogene family-like 6 JBrowse link 3 2,806,777 2,832,697 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rif1 replication timing regulatory factor 1 JBrowse link 3 37,599,540 37,648,818 RGD:6480464
G Rorc RAR-related orphan receptor C JBrowse link 2 195,612,471 195,636,797 RGD:6480464
G Rpusd3 RNA pseudouridine synthase D3 JBrowse link 4 145,361,937 145,370,992 RGD:6480464
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 JBrowse link 9 11,031,847 11,055,285 RGD:6480464
G Slc16a1 solute carrier family 16 member 1 JBrowse link 2 207,108,552 207,129,352 RGD:6480464
G Slc25a3 solute carrier family 25 member 3 JBrowse link 7 31,816,601 31,824,064 RGD:6480464
G Srsf1 serine and arginine rich splicing factor 1 JBrowse link 10 75,334,200 75,341,197 RGD:6480464
G Sult1a1 sulfotransferase family 1A member 1 JBrowse link 1 198,100,586 198,104,106 RGD:6480464
G Sult1e1 sulfotransferase family 1E member 1 JBrowse link 14 22,070,861 22,089,264 RGD:6480464
G Sult2a1 sulfotransferase family 2A member 1 JBrowse link 1 76,558,721 76,614,315 RGD:6480464
G Susd6 sushi domain containing 6 JBrowse link 6 104,437,104 104,532,522 RGD:6480464
G Syk spleen associated tyrosine kinase JBrowse link 17 12,614,311 12,669,568 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link 9 20,546,159 20,621,051 RGD:6480464
G Tubb5 tubulin, beta 5 class I JBrowse link 20 3,422,448 3,426,420 RGD:6480464
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:6480464
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 JBrowse link 18 28,561,957 28,603,335 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:6480464
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 9 95,221,474 95,302,822 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464
G Wdr74 WD repeat domain 74 JBrowse link 1 224,933,906 224,938,659 RGD:6480464
G Wwc2 WW and C2 domain containing 2 JBrowse link 16 47,368,768 47,533,816 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      application 19308
        pharmaceutical 19179
          drug 19179
            antineoplastic agent 16732
              biochanin A 78
                2,3-dihydrobiochanin A 0
                biochanin A 7-O-(6-O-malonyl-beta-D-glucoside) 0
                biochanin A 7-O-beta-D-glucoside 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      ketone 15909
                                        cyclic ketone 13335
                                          isoflavones 2619
                                            methoxyisoflavone 230
                                              4'-methoxyisoflavones 125
                                                biochanin A 78
                                                  2,3-dihydrobiochanin A 0
                                                  biochanin A 7-O-(6-O-malonyl-beta-D-glucoside) 0
                                                  biochanin A 7-O-beta-D-glucoside 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.