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ONTOLOGY REPORT - ANNOTATIONS


Term:alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group
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Accession:CHEBI:17785 term browser browse the term
Definition:An N-acetyl-D-glucosaminyl group comprising one N-acetylated glucosamine and two galactose residues, linked as shown. A trisaccharide antigen found in all animals apart from Old World primates and humans, it is the main xenoantigen hampering the success of clinical xenotransplantation. Obtained formally by removing the hydroxy group from the hemiacetal function of the amino trisaccharide alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosamine.
Synonyms:exact_synonym: alpha-D-galactopyranosyl-(1->3) beta-D-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-D-glucopyranosyl
 related_synonym: Formula=C20H34NO15;   Gal(alpha1->3)-Gal(beta1->4)-GlcNAc-R;   Galalpha1-3Galbeta1-4GlcNAc-;   Galalpha1-3LacNAc-;   alpha-D-Gal(1->3)-beta-D-Gal(1->4)-D-GlcNAc-yl group;   alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-GlcNHAc-R;   alpha-D-Galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-N-acetylglucosaminyl-R;   alpha-D-Galactosyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R;   alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-Glcp-NAc-yl group;   alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNHAc-R;   alpha-D-galactopyranosyl-(1->3) beta-D-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-D-glucopyranosyl group;   alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-N-acetyl-D-glucosaminyl group;   alpha-D-galactosyl-beta-1,3-D-galactosyl-beta-1,4-N-acetyl-D-glucosaminyl group;   alpha-Gal trisaccharide;   alpha-Gal trisaccharide epitope;   alpha-Gal3;   alpha-gal;   alpha-galactosyl epitope
 alt_id: CHEBI:10237;   CHEBI:12312;   CHEBI:22376;   CHEBI:22381;   CHEBI:59172;   CHEBI:60181
 xref: KEGG:C04855;   PMID:11855872 "Europe PMC";   PMID:14687940 "Europe PMC";   PMID:16266320 "Europe PMC";   PMID:19501971 "Europe PMC";   PMID:24635119 "Europe PMC";   PMID:24750173 "Europe PMC";   PMID:25297927 "Europe PMC";   PMID:25940316 "Europe PMC";   PMID:29187897 "Europe PMC"


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Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        epitope 6771
          alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group 0
            alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc-yl group 0
            biotinylated alpha-gal 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            heteroorganic entity 19055
                              organochalcogen compound 18777
                                organooxygen compound 18689
                                  carbohydrates and carbohydrate derivatives 12088
                                    carbohydrate 12088
                                      oligosaccharide 436
                                        oligosaccharide derivative 115
                                          amino oligosaccharide 0
                                            glucosamine oligosaccharide 0
                                              alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-D-GlcNAc 0
                                                alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-D-GlcpNAc-yl group 0
                                                  alpha-D-Galp-(1->3)-beta-D-Galp-(1->4)-beta-D-GlcpNAc-yl group 0
                                                  biotinylated alpha-gal 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.