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ONTOLOGY REPORT - ANNOTATIONS


Term:phylloquinone
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Accession:CHEBI:18067 term browser browse the term
Definition:A member of the class of phylloquinones that consists of 1,4-naphthoquinone having methyl and phytyl groups at positions 2 and 3 respectively. The parent of the class of phylloquinones.
Synonyms:related_synonym: 2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione;   2-Methyl-3-[(2E)-3,7,11,15-tetramethyl-2-hexadecenyl]naphthoquinone;   2-Methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-yl]naphthalene-1,4-dione;   2-Methyl-3-phytyl-1,4-naphthochinon;   2-Methyl-3-phytyl-1,4-naphthoquinone;   3-Phytylmenadione;   Formula=C31H46O2;   InChI=1S/C31H46O2/c1-22(2)12-9-13-23(3)14-10-15-24(4)16-11-17-25(5)20-21-27-26(6)30(32)28-18-7-8-19-29(28)31(27)33/h7-8,18-20,22-24H,9-17,21H2,1-6H3/b25-20+/t23-,24-/m1/s1;   InChIKey=MBWXNTAXLNYFJB-NKFFZRIASA-N;   Phyllochinon;   Phyllochinonum;   Phytomenadione;   Phytonadione;   Phytonadionum;   Phytylmenadione;   SMILES=CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC\\C(C)=C\\CC1=C(C)C(=O)c2ccccc2C1=O;   Vitamin K1;   alpha-phylloquinone;   fitomenadiona;   phytomenadionum;   trans-Phylloquinone
 alt_id: CHEBI:11611;   CHEBI:14833;   CHEBI:26105;   CHEBI:45148;   CHEBI:8181
 xref: CAS:84-80-0 "ChemIDplus";   CAS:84-80-0 "KEGG COMPOUND";   CAS:84-80-0 "NIST Chemistry WebBook";   DrugBank:DB01022;   Drug_Central:2843 "DrugCentral";   HMDB:HMDB0003555;   KEGG:C02059;   KEGG:D00148;   KNApSAcK:C00002868
 xref_mesh: MESH:D010837
 xref: PDBeChem:PQN;   PMID:11003724 "Europe PMC";   PMID:15686525 "Europe PMC";   PMID:19588895 "Europe PMC";   PMID:19996170 "Europe PMC";   PMID:21169510 "Europe PMC";   PMID:21645693 "Europe PMC";   PMID:21844348 "Europe PMC";   PMID:21914559 "Europe PMC";   Reaxys:2568816 "Reaxys";   Wikipedia:Phytonadione


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phylloquinone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Axl Axl receptor tyrosine kinase JBrowse link 1 82,550,892 82,580,761 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:6480464
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:6480464
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:6480464
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Gas6 growth arrest specific 6 JBrowse link 16 81,213,364 81,243,824 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mgp matrix Gla protein JBrowse link 4 170,856,783 170,860,105 RGD:6480464
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6480464
G Tagln transgelin JBrowse link 8 50,222,895 50,228,369 RGD:6480464
vitamin K term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:6480464
G Axin2 axin 2 JBrowse link 10 97,212,483 97,238,824 RGD:6480464
G Axl Axl receptor tyrosine kinase JBrowse link 1 82,550,892 82,580,761 RGD:6480464
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cnn1 calponin 1 JBrowse link 8 23,113,083 23,121,748 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 JBrowse link 8 62,798,317 62,809,848 RGD:6480464
G Fgg fibrinogen gamma chain JBrowse link 2 181,987,080 181,994,523 RGD:6480464
G Fnta farnesyltransferase, CAAX box, alpha JBrowse link 16 70,834,957 70,854,724 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Lss lanosterol synthase JBrowse link 20 12,844,522 12,870,474 RGD:6480464
G Mgp matrix Gla protein JBrowse link 4 170,856,783 170,860,105 RGD:6480464
G Mvd mevalonate diphosphate decarboxylase JBrowse link 19 55,258,910 55,268,933 RGD:6480464
G Myh1 myosin heavy chain 1 JBrowse link 10 53,740,841 53,764,610 RGD:6480464
G Numb NUMB, endocytic adaptor protein JBrowse link 6 107,279,917 107,325,345 RGD:6480464
G Orm1 orosomucoid 1 JBrowse link 5 79,179,668 79,182,820 RGD:6480464
G Pros1 protein S JBrowse link 7 1,206,648 1,288,140 RGD:6480464
G Pth parathyroid hormone JBrowse link 1 178,215,829 178,218,761 RGD:6480464
G Rabggta Rab geranylgeranyltransferase subunit alpha JBrowse link 15 34,393,419 34,400,466 RGD:6480464
G Rabggtb Rab geranylgeranyltransferase subunit beta JBrowse link 2 260,110,309 260,115,574 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator JBrowse link 19 561,696 564,929 RGD:6480464
G Runx2 RUNX family transcription factor 2 JBrowse link 9 18,564,743 18,773,092 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6480464
G Tagln transgelin JBrowse link 8 50,222,895 50,228,369 RGD:6480464
G Tcf4 transcription factor 4 JBrowse link 18 65,285,320 65,507,983 RGD:6480464
G Tgm2 transglutaminase 2 JBrowse link 3 154,597,165 154,627,257 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Ubiad1 UbiA prenyltransferase domain containing 1 JBrowse link 5 165,247,630 165,259,228 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          cofactor 15848
            phylloquinone 47
              vitamin K + 33
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      ketone 15789
                                        cyclic ketone 13094
                                          quinone 8224
                                            naphthoquinone 1413
                                              phytylnaphthoquinone 49
                                                phylloquinones 47
                                                  phylloquinone 47
                                                    vitamin K + 33
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.