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ONTOLOGY REPORT - ANNOTATIONS


Term:gamma-tocopherol
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Accession:CHEBI:18185 term browser browse the term
Definition:A tocopherol in which the chroman-6-ol core is substituted by methyl groups at positions 7 and 8. It is found particularly in maize (corn) oil and soya bean (soybean) oils.
Synonyms:exact_synonym: (2R)-2,7,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-chromen-6-ol
 related_synonym: (2R)-3,4-dihydro-2,7,8-trimethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol;   7,8-dimethyltocol;   D-gamma-tocopherol;   Formula=C28H48O2;   InChI=1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3/t21-,22-,28-/m1/s1;   InChIKey=QUEDXNHFTDJVIY-DQCZWYHMSA-N;   SMILES=CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2cc(O)c(C)c(C)c2O1
 alt_id: CHEBI:10579;   CHEBI:12406;   CHEBI:24199;   MESH:D024504
 xref: Beilstein:93072 "Beilstein";   CAS:54-28-4 "ChemIDplus";   CAS:54-28-4 "KEGG COMPOUND";   HMDB:HMDB0001492;   KEGG:C02483;   KNApSAcK:C00007365;   LIPID_MAPS_instance:LMPR02020065 "LIPID MAPS"
 xref_mesh: MESH:D024505
 xref: MetaCyc:GAMA-TOCOPHEROL;   PMID:15256801 "Europe PMC";   PMID:22513202 "Europe PMC";   PMID:22607470 "Europe PMC";   PMID:22888664 "Europe PMC";   PMID:23429409 "Europe PMC";   Reaxys:93072 "Reaxys";   Wikipedia:Gamma-Tocopherol


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gamma-tocopherol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc1 ATP binding cassette subfamily C member 1 JBrowse link 10 549,537 672,235 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Arf3 ADP-ribosylation factor 3 JBrowse link 7 140,412,463 140,438,751 RGD:6480464
G Aspm abnormal spindle microtubule assembly JBrowse link 13 56,546,021 56,591,793 RGD:6480464
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:6480464
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 JBrowse link 10 56,205,622 56,211,879 RGD:6480464
G Aurka aurora kinase A JBrowse link 3 170,364,177 170,380,278 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Birc5 baculoviral IAP repeat-containing 5 JBrowse link 10 106,856,097 106,864,419 RGD:6480464
G Camk2g calcium/calmodulin-dependent protein kinase II gamma JBrowse link 15 3,936,721 3,995,740 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccnb2 cyclin B2 JBrowse link 8 76,847,972 76,861,165 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccnd3 cyclin D3 JBrowse link 9 15,404,816 15,410,905 RGD:6480464
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:6480464
G Cdc6 cell division cycle 6 JBrowse link 10 86,819,477 86,833,301 RGD:6480464
G Cdk1 cyclin-dependent kinase 1 JBrowse link 20 20,576,341 20,591,510 RGD:6480464
G Cdk2 cyclin dependent kinase 2 JBrowse link 7 3,124,953 3,132,533 RGD:6480464
G Cdk4 cyclin-dependent kinase 4 JBrowse link 7 70,345,971 70,352,689 RGD:6480464
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 JBrowse link 10 67,862,054 67,863,255 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:6480464
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:6480464
G Clec4e C-type lectin domain family 4, member E JBrowse link 4 156,271,087 156,276,243 RGD:6480464
G Cplx1 complexin 1 JBrowse link 14 2,194,895 2,226,610 RGD:6480464
G Cplx2 complexin 2 JBrowse link 17 10,756,871 10,828,811 RGD:6480464
G Crabp2 cellular retinoic acid binding protein 2 JBrowse link 2 187,322,416 187,326,794 RGD:6480464
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6480464
G Csf1r colony stimulating factor 1 receptor JBrowse link 18 56,414,493 56,458,300 RGD:6480464
G Csrp2 cysteine and glycine-rich protein 2 JBrowse link 7 53,630,675 53,649,309 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Dnajc5 DnaJ heat shock protein family (Hsp40) member C5 JBrowse link 3 177,012,714 177,047,787 RGD:6480464
G E2f1 E2F transcription factor 1 JBrowse link 3 150,062,895 150,073,721 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:6480464
G Fcer1a Fc fragment of IgE receptor Ia JBrowse link 13 91,727,253 91,737,106 RGD:6480464
G Fes FES proto-oncogene, tyrosine kinase JBrowse link 1 142,174,648 142,183,884 RGD:6480464
G Fgf1 fibroblast growth factor 1 JBrowse link 18 32,273,830 32,359,831 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 2 124,081,072 124,134,133 RGD:6480464
G Fgfr1 Fibroblast growth factor receptor 1 JBrowse link 16 71,265,390 71,319,046 RGD:6480464
G Fkbp9 FKBP prolyl isomerase 9 JBrowse link 4 87,167,514 87,234,198 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 JBrowse link 2 179,584,302 179,704,629 RGD:6480464
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 JBrowse link 3 2,507,745 2,534,664 RGD:6480464
G Gstm1 glutathione S-transferase mu 1 JBrowse link 2 210,803,869 210,809,461 RGD:6480464
G Gsto1 glutathione S-transferase omega 1 JBrowse link 1 267,607,437 267,617,387 RGD:6480464
G Haspin histone H3 associated protein kinase JBrowse link 10 59,695,403 59,698,398 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Kif20a kinesin family member 20A JBrowse link 18 27,424,328 27,432,814 RGD:6480464
G Kif4a kinesin family member 4A JBrowse link X 70,461,700 70,561,084 RGD:6480464
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:6480464
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link 1 214,725,482 214,756,653 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Napb NSF attachment protein beta JBrowse link 3 143,017,571 143,063,904 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase JBrowse link 10 91,879,608 91,986,242 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 3 124,880,698 124,884,570 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ppp3ca protein phosphatase 3 catalytic subunit alpha JBrowse link 2 241,909,332 242,186,861 RGD:6480464
G Prtn3 proteinase 3 JBrowse link 7 12,643,712 12,646,951 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Ptpro protein tyrosine phosphatase, receptor type, O JBrowse link 4 171,250,766 171,461,571 RGD:6480464
G Rab11b RAB11B, member RAS oncogene family JBrowse link 7 18,598,991 18,612,132 RGD:6480464
G Rab3a RAB3A, member RAS oncogene family JBrowse link 16 20,435,098 20,439,206 RGD:6480464
G Rab6b RAB6B, member RAS oncogene family JBrowse link 8 111,600,375 111,668,817 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Rrm1 ribonucleotide reductase catalytic subunit M1 JBrowse link 1 167,538,387 167,562,688 RGD:6480464
G Rrm2 ribonucleotide reductase regulatory subunit M2 JBrowse link 6 43,884,627 43,890,818 RGD:6480464
G Snca synuclein alpha JBrowse link 4 90,782,412 90,883,236 RGD:6480464
G Sncb synuclein, beta JBrowse link 17 10,384,472 10,392,776 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Stx1a syntaxin 1A JBrowse link 12 24,682,050 24,710,002 RGD:6480464
G Stxbp1 syntaxin binding protein 1 JBrowse link 3 11,823,779 11,885,479 RGD:6480464
G Sv2a synaptic vesicle glycoprotein 2a JBrowse link 2 198,321,100 198,336,889 RGD:6480464
G Syn1 synapsin I JBrowse link X 1,321,315 1,379,202 RGD:6480464
G Syn2 synapsin II JBrowse link 4 147,037,179 147,195,096 RGD:6480464
G Syngr1 synaptogyrin 1 JBrowse link 7 121,311,008 121,334,437 RGD:6480464
G Syp synaptophysin JBrowse link X 15,694,699 15,709,244 RGD:6480464
G Syt11 synaptotagmin 11 JBrowse link 2 188,112,301 188,138,180 RGD:6480464
G Syt13 synaptotagmin 13 JBrowse link 3 81,814,287 81,852,454 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfaip2 TNF alpha induced protein 2 JBrowse link 6 135,890,869 135,903,647 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Ttc3 tetratricopeptide repeat domain 3 JBrowse link 11 34,598,324 34,739,986 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:6480464
G Vamp2 vesicle-associated membrane protein 2 JBrowse link 10 55,675,171 55,679,405 RGD:6480464
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      chemical role 19171
        antioxidant 14106
          food antioxidant 831
            gamma-tocopherol 97
              13-hydroxy-gamma-tocopherol 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic heterocyclic compound 18245
                                  oxacycle 17014
                                    benzopyran 9473
                                      1-benzopyran 9168
                                        chromanes 3922
                                          chromanol 1725
                                            chroman-6-ol 1725
                                              vitamin E 1725
                                                tocopherol 217
                                                  gamma-tocopherol 97
                                                    13-hydroxy-gamma-tocopherol 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.