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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:zymosterol
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Accession:CHEBI:18252 term browser browse the term
Definition:A 3beta-sterol that has formula C27H44O.
Synonyms:related_synonym: 5alpha-Cholesta-8,24-dien-3beta-ol;   Formula=C27H44O;   InChI=1S/C27H44O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h7,19-21,23-24,28H,6,8-17H2,1-5H3/t19-,20+,21+,23-,24+,26+,27-/m1/s1;   InChIKey=CGSJXLIKVBJVRY-XTGBIJOFSA-N;   SMILES=[H][C@@]12CCC3=C(CC[C@]4(C)[C@]([H])(CC[C@@]34[H])[C@H](C)CCC=C(C)C)[C@@]1(C)CC[C@H](O)C2;   delta8,24-Cholestadien-3beta-ol;   zymostrol
 alt_id: CHEBI:10131;   CHEBI:12172;   CHEBI:20646;   CHEBI:27370
 xref: Beilstein:2568614;   CAS:128-33-6;   KEGG:C05437;   KNApSAcK:C00023749;   LIPID_MAPS_instance:LMST01010066
 xref_mesh: MESH:C015582


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zymosterol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 increases metabolic processing ISO CYP27A1 protein results in increased metabolism of zymosterol CTD PMID:14622972 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Msmo1 methylsterol monooxygenase 1 decreases abundance ISO MSMO1 protein results in decreased abundance of zymosterol metabolite CTD PMID:23125191 NCBI chr16:26,859,441...26,875,880
Ensembl chr16:26,859,397...26,875,973
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        biochemical role 19281
          metabolite 19262
            eukaryotic metabolite 18906
              fungal metabolite 17407
                Saccharomyces cerevisiae metabolite 16470
                  zymosterol 2
                    26,27-dehydrozymosterol 0
                    3-dehydro-4-carboxyzymosterol 0
                    3-dehydro-4-methylzymosterol + 0
                    4-carboxy-4-methylzymosterol 0
                    4-carboxyzymosterol 0
                    4-formylzymosterol + 0
                    4-hydroxymethylzymosterol + 0
                    4-methylzymosterol 0
                    4alpha-hydroxymethyl-4beta-methylzymosterol 0
                    4alpha-methylzymosterol + 0
                    4beta-methylzymosterol-4-carbaldehyde 0
                    4beta-methylzymosterol-4alpha-carboxylic acid 0
                    zymosterol ester + 0
                    zymosterol intermediate 1c 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic molecule 19486
                              organic cyclic compound 19282
                                organic polycyclic compound 16384
                                  steroid 12788
                                    hydroxy steroid 12371
                                      3-hydroxy steroid 9999
                                        sterol 417
                                          3beta-sterol 411
                                            zymosterol 2
                                              26,27-dehydrozymosterol 0
                                              3-dehydro-4-carboxyzymosterol 0
                                              3-dehydro-4-methylzymosterol + 0
                                              4-carboxy-4-methylzymosterol 0
                                              4-carboxyzymosterol 0
                                              4-formylzymosterol + 0
                                              4-hydroxymethylzymosterol + 0
                                              4-methylzymosterol 0
                                              4alpha-hydroxymethyl-4beta-methylzymosterol 0
                                              4alpha-methylzymosterol + 0
                                              4beta-methylzymosterol-4-carbaldehyde 0
                                              4beta-methylzymosterol-4alpha-carboxylic acid 0
                                              zymosterol ester + 0
                                              zymosterol intermediate 1c 0
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