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ONTOLOGY REPORT - ANNOTATIONS


Term:SAICAR
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Accession:CHEBI:18319 term browser browse the term
Definition:A 1-(phosphoribosyl)imidazolecarboxamide resulting from the formal condesation of the darboxy group of 5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid with the amino group of L-aspartic acid.
Synonyms:exact_synonym: (2S)-2-[5-amino-1-(5-O-phosphono-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid;   N-{[5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazol-4-yl]carbonyl}-L-aspartic acid
 related_synonym: (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid;   (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido]succinate;   1-(5'-Phosphoribosyl)-4-(N-succinocarboxamide)-5-aminoimidazole;   1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole;   5'-Phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole;   Formula=C13H19N4O12P;   InChI=1S/C13H19N4O12P/c14-10-7(11(22)16-4(13(23)24)1-6(18)19)15-3-17(10)12-9(21)8(20)5(29-12)2-28-30(25,26)27/h3-5,8-9,12,20-21H,1-2,14H2,(H,16,22)(H,18,19)(H,23,24)(H2,25,26,27)/t4-,5+,8+,9+,12+/m0/s1;   InChIKey=NAQGHJTUZRHGAC-ZZZDFHIKSA-N;   SAICA riboside;   SMILES=Nc1c(ncn1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O)C(=O)N[C@@H](CC(O)=O)C(O)=O;   Succino-AICAR;   succinyl-5-aminoimidazole-4-carboxamide-1-ribose-5-phosphate;   succinylaminoimidazolecarboxamide ribose-5'-phosphate
 alt_id: CHEBI:11028;   CHEBI:18965;   CHEBI:572;   CHEBI:78110
 xref: CAS:3031-95-6 "ChemIDplus";   CAS:3031-95-6 "KEGG COMPOUND";   HMDB:HMDB0000797;   KEGG:C04823
 xref_mesh: MESH:C020635
 xref: MetaCyc:P-RIBOSYL-4-SUCCCARB-AMINOIMIDAZOLE;   PMID:23086999 "Europe PMC";   PMID:24606918 "SUBMITTER";   Wikipedia:Phosphoribosylaminoimidazolesuccinocarboxamide
 cyclic_relationship: is_conjugate_acid_of CHEBI:58443


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SAICAR term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pkm pyruvate kinase M1/2 JBrowse link 8 64,480,963 64,502,957 RGD:6480464

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  CHEBI ontology 19669
    role 19613
      application 19235
        pharmaceutical 19097
          drug 19097
            anti-ulcer drug 751
              succinic acid 202
                SAICAR 1
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  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      chalcogen 19233
                        oxygen atom 19188
                          oxygen molecular entity 19188
                            hydroxides 18965
                              oxoacid 18076
                                pnictogen oxoacid 8534
                                  phosphorus oxoacid 8429
                                    phosphoric acids 7314
                                      phosphoric acid 7314
                                        phosphoric acid derivative 6965
                                          phosphate 6965
                                            organic phosphate 6964
                                              carbohydrate phosphate 1496
                                                phospho sugar 1431
                                                  aldose phosphate 1429
                                                    aldopentose phosphate 1423
                                                      ribose phosphate 1417
                                                        1-(phosphoribosyl)imidazole 105
                                                          1-(phosphoribosyl)imidazolecarboxamide 105
                                                            SAICAR 1
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