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ONTOLOGY REPORT - ANNOTATIONS


Term:lanostane
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Accession:CHEBI:20265 term browser browse the term
Definition:A triterpene that has formula C30H54.
Synonyms:related_synonym: (5alpha)-4,4,14-trimethylcholestane;   4,4,14-trimethylcholestane;   Formula=C30H54;   InChI=1S/C30H54/c1-21(2)11-9-12-22(3)23-15-19-30(8)25-13-14-26-27(4,5)17-10-18-28(26,6)24(25)16-20-29(23,30)7/h21-26H,9-20H2,1-8H3/t22-,23-,24+,25-,26+,28-,29-,30+/m1/s1;   InChIKey=ZQIOPEXWVBIZAV-ZKYCIREVSA-N;   SMILES=[H][C@@]1(CC[C@@]2(C)[C@]3([H])CC[C@@]4([H])C(C)(C)CCC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C;   [5S-[5alpha,8beta,9alpha,10beta,13beta,14alpha,17beta(S*)]]-17-(1,5-dimethylhexyl)hexadecahydro-4,4,10,13,14-pentamethyl-1H-cyclopenta[a]phenanthrene
 xref: Beilstein:3137145 "Beilstein";   CAS:474-20-4 "ChemIDplus";   CAS:474-20-4 "NIST Chemistry WebBook"


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14-demethyllanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Msmo1 methylsterol monooxygenase 1 JBrowse link 16 26,859,441 26,875,880 RGD:6480464
24,25-dihydrolanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:6480464
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
3beta-hydroxylanost-8-en-32-al term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
cucurbitacin B term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acta2 actin alpha 2, smooth muscle JBrowse link 1 252,537,614 252,550,394 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6480464
G Cebpa CCAAT/enhancer binding protein alpha JBrowse link 1 91,363,492 91,366,164 RGD:6480464
G Cebpd CCAAT/enhancer binding protein delta JBrowse link 11 89,008,008 89,009,146 RGD:6480464
G Col1a1 collagen type I alpha 1 chain JBrowse link 10 82,745,801 82,762,790 RGD:6480464
G Fabp4 fatty acid binding protein 4 JBrowse link 2 93,792,666 93,797,267 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Klf5 Kruppel-like factor 5 JBrowse link 15 83,703,796 83,722,921 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
cycloartenol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Cryz crystallin zeta JBrowse link 2 260,884,315 260,911,827 RGD:6480464
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:6480464
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:6480464
ganoderol B term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Srd5a1 steroid 5 alpha-reductase 1 JBrowse link 1 36,320,504 36,354,694 RGD:6480464
lanost-8-ene-3beta,30-diol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase JBrowse link 2 27,480,224 27,500,654 RGD:6480464
lanosterol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 JBrowse link 9 81,968,285 81,998,213 RGD:6480464
G Cyp51 cytochrome P450, family 51 JBrowse link 4 27,175,564 27,194,018 RGD:6480464
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:6480464
G Ephx2 epoxide hydrolase 2 JBrowse link 15 42,757,241 42,794,211 RGD:6480464
G Marchf6 membrane associated ring-CH-type finger 6 JBrowse link 2 84,533,546 84,608,743 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    chemical entity 19726
      atom 19724
        nonmetal atom 19597
          carbon atom 19494
            organic molecular entity 19494
              organic fundamental parent 17545
                natural product fundamental parent 12777
                  terpenoid fundamental parent 1839
                    lanostane 31
                      (24R)-24-methylcycloart-25-en-3beta-ol 0
                      25-hydroxy-3-epidehydrotumulosic acid 0
                      3beta-hydroxylanost-8-en-32-al 1
                      4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol 0
                      4alpha-hydroxymethyl-4beta-methylzymosterol 0
                      4beta-methylzymosterol-4-carbaldehyde 0
                      9beta-9,19-cyclolanost-24-ene-3beta,28-diol + 0
                      colossolactone V 0
                      colossolactone VIII 0
                      cucurbitacin B + 18
                      cucurbitacin D 0
                      cycloartane + 0
                      cycloartenol + 6
                      dehydroeburiconic acid 0
                      fomitopinic acid A 0
                      fomitoside E 0
                      fomitoside F 0
                      ganoderol B 2
                      ganoderone A 0
                      ganoderone C 0
                      holothurin A3 acid 0
                      holothurin A4 acid 0
                      lanost-8-ene-3beta,30-diol 1
                      lanosta-9(11),24-dien-3-one 0
                      lanostane derivative + 0
                      lanosterol + 6
                      lucialdehyde B 0
                      lucialdehyde C 0
                      mollisoside A 0
                      neothyonidioside 0
                      parkeol 0
                      sclerodol B 0
                      stichloroside C1 0
                      suberosol 0
                      tsugarioside C 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    main group molecular entity 19610
                      s-block molecular entity 19378
                        hydrogen molecular entity 19367
                          hydrides 18278
                            organic hydride 17545
                              organic fundamental parent 17545
                                hydrocarbon 16957
                                  terpene 9326
                                    triterpene 640
                                      lanostane 31
                                        (24R)-24-methylcycloart-25-en-3beta-ol 0
                                        25-hydroxy-3-epidehydrotumulosic acid 0
                                        3beta-hydroxylanost-8-en-32-al 1
                                        4alpha-carboxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol 0
                                        4alpha-hydroxymethyl-4beta-methylzymosterol 0
                                        4beta-methylzymosterol-4-carbaldehyde 0
                                        9beta-9,19-cyclolanost-24-ene-3beta,28-diol + 0
                                        colossolactone V 0
                                        colossolactone VIII 0
                                        cucurbitacin B + 18
                                        cucurbitacin D 0
                                        cycloartane + 0
                                        cycloartenol + 6
                                        dehydroeburiconic acid 0
                                        fomitopinic acid A 0
                                        fomitoside E 0
                                        fomitoside F 0
                                        ganoderol B 2
                                        ganoderone A 0
                                        ganoderone C 0
                                        holothurin A3 acid 0
                                        holothurin A4 acid 0
                                        lanost-8-ene-3beta,30-diol 1
                                        lanosta-9(11),24-dien-3-one 0
                                        lanostane derivative + 0
                                        lanosterol + 6
                                        lucialdehyde B 0
                                        lucialdehyde C 0
                                        mollisoside A 0
                                        neothyonidioside 0
                                        parkeol 0
                                        sclerodol B 0
                                        stichloroside C1 0
                                        suberosol 0
                                        tsugarioside C 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.