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Accession:CHEBI:204928 term browser browse the term
Definition:A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups.
Synonyms:exact_synonym: 3-(acetoxymethyl)-7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (6R,7R)-3-(acetoxymethyl)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   (6R,7R)-3-Acetoxymethyl-7-{2-(2-amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   (6R,7R,Z)-3-(acetoxymethyl)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   Cephotaxime;   Formula=C16H17N5O7S2;   InChI=1S/C16H17N5O7S2/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26)/b20-9-/t10-,14-/m1/s1;   InChIKey=GPRBEKHLDVQUJE-QSWIMTSFSA-N;   SMILES=[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1csc(N)n1)C(O)=O;   cefotaxima;   cefotaximum
 alt_id: CHEBI:112504;   CHEBI:3497;   CHEBI:41475
 xref: Beilstein:1096643 "Beilstein";   CAS:63527-52-6 "ChemIDplus";   CAS:63527-52-6 "DrugBank";   CAS:63527-52-6 "KEGG COMPOUND";   CAS:63527-52-6 "KEGG DRUG";   DrugBank:DB00493;   Drug_Central:546 "DrugCentral";   KEGG:C06885;   KEGG:D07647
 xref_mesh: MESH:D002439
 xref: PDBeChem:CE3;   PMID:10866367 "ChEMBL";   PMID:11034276 "Europe PMC";   PMID:11061623 "Europe PMC";   PMID:11677129 "ChEMBL";   PMID:12833570 "Europe PMC";   PMID:1384868 "Europe PMC";   PMID:14512220 "Europe PMC";   PMID:1502708 "Europe PMC";   PMID:15164972 "Europe PMC";   PMID:15361989 "Europe PMC";   PMID:15969234 "Europe PMC";   PMID:1635063 "ChEMBL";   PMID:17006042 "Europe PMC";   PMID:17386217 "Europe PMC";   PMID:18611527 "Europe PMC";   PMID:19741292 "Europe PMC";   PMID:21425867 "Europe PMC";   PMID:24038683 "Europe PMC";   PMID:24211456 "Europe PMC";   PMID:29017833 "Europe PMC";   PMID:9131470 "Europe PMC";   Patent:DE2556736;   Patent:DE2702501;   Patent:US4098888;   Patent:US4152432;   Reaxys:1096643 "Reaxys";   Wikipedia:Cefotaxime
 cyclic_relationship: is_conjugate_acid_of CHEBI:53670

show annotations for term's descendants       view all columns           Sort by:
cefotaxime term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Pgd phosphogluconate dehydrogenase JBrowse link 5 165,966,128 165,982,327 RGD:6480464
G RT1-CE5 RT1 class I, locus CE5 JBrowse link 20 4,892,702 4,896,993 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19741
    role 19688
      biological role 19686
        antimicrobial agent 17215
          antibacterial agent 12930
            antibacterial drug 3089
              cefotaxime 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19741
    subatomic particle 19737
      composite particle 19737
        hadron 19737
          baryon 19737
            nucleon 19737
              atomic nucleus 19737
                atom 19737
                  main group element atom 19622
                    p-block element atom 19622
                      carbon group element atom 19515
                        carbon atom 19508
                          organic molecular entity 19508
                            organic group 18423
                              organic divalent group 18414
                                organodiyl group 18414
                                  carbonyl group 18301
                                    carbonyl compound 18301
                                      carboxylic acid 17966
                                        carboacyl group 17073
                                          univalent carboacyl group 17073
                                            carbamoyl group 16800
                                              carboxamide 16800
                                                lactam 7679
                                                  beta-lactam 784
                                                    beta-lactam antibiotic 772
                                                      cephem 538
                                                        cephalosporin 537
                                                          cefotaxime 5
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.