5,6,7,8-tetrahydrofolic acid - Ontology Report - Chinchilla Research Resource Database

ONTOLOGY REPORT - ANNOTATIONS

Term:	5,6,7,8-tetrahydrofolic acid	go back to main search page
Accession:	CHEBI:20506	browse the term
Definition:	A tetrahydrofolic acid that has formula C19H23N7O6.
Synonyms:	exact_synonym:	N-[4-{[(2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}benzoyl]-L-glutamic acid
	related_synonym:	(6S)-THFA; (6S)-Tetrahydrofolate; (6S)-Tetrahydrofolic acid; 5,6,7,8-Tetrahydrofolate; Formula=C19H23N7O6; InChI=1S/C19H23N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,11-12,21,23H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t11?,12-/m0/s1; InChIKey=MSTNYGQPCMXVAQ-KIYNQFGBSA-N; SMILES=Nc1nc2NCC(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)Nc2c(=O)[nH]1; THF; tetrahydrofolate; tetrahydrofolic acid
	xref:	Beilstein:101189 "Beilstein"; CAS:135-16-0 "ChemIDplus"; CAS:135-16-0 "KEGG COMPOUND"; DrugBank:DB00116; KEGG:C00101; KNApSAcK:C00007249
	xref_mesh:	MESH:C030371
	cyclic_relationship:	is_conjugate_acid_of CHEBI:68437

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Genes (6)

5,6,7,8-tetrahydrofolic acid

Symbol

Object Name

JBrowse

Chr

Start

Stop

Reference

Aldh1l2

aldehyde dehydrogenase 1 family, member L2

26,375,866

26,425,838

alkaline phosphatase, intestinal

94,197,616

94,201,910

insulin-like growth factor 1 receptor

128,924,921

129,213,816

5-methyltetrahydrofolate-homocysteine methyltransferase

66,210,444

66,295,014

solute carrier family 19 member 1

12,334,675

12,354,517

thymidylate synthetase

121,918,875

121,931,564

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19716
role	19663
biological role	19661
biochemical role	19179
metabolite	19151
eukaryotic metabolite	18770
fungal metabolite	17364
Saccharomyces cerevisiae metabolite	16385
5,6,7,8-tetrahydrofolic acid	6
(6S)-5,6,7,8-tetrahydrofolic acid	0
Path 2
Term	Annotations
CHEBI ontology	19716
subatomic particle	19712
composite particle	19712
hadron	19712
baryon	19712
nucleon	19712
atomic nucleus	19712
atom	19712
main group element atom	19598
p-block element atom	19598
carbon group element atom	19486
carbon atom	19480
organic molecular entity	19480
organic group	18407
organic divalent group	18397
organodiyl group	18397
carbonyl group	18285
carbonyl compound	18285
carboxylic acid	17940
amino acid	12442
alpha-amino acid	7648
L-alpha-amino acid	7312
glutamine family amino acid	5349
L-glutamic acid	5251
L-glutamic acid derivative	3714
folic acids	3710
tetrahydrofolic acid	63
5,6,7,8-tetrahydrofolic acid	6
(6S)-5,6,7,8-tetrahydrofolic acid	0

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

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