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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:N-acylglucosamine
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Accession:CHEBI:21638 term browser browse the term
Synonyms:related_synonym: N-acylglucosamines


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chitin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chit1 chitinase 1 affects binding ISO CHIT1 protein binds to Chitin CTD PMID:16005164 NCBI chr13:50,947,020...50,994,644
Ensembl chr13:50,974,872...50,994,643
JBrowse link
G Igf1r insulin-like growth factor 1 receptor multiple interactions ISO [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of IGF1R mRNA CTD PMID:30041514 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of MMP9 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of MMP9 mRNA]; [Docetaxel binds to Chitin] which results in decreased expression of MMP9 mRNA; [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of MMP9 mRNA CTD PMID:30041514 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Muc1 mucin 1, cell surface associated affects binding
multiple interactions
ISO [Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein
[[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of MMP9 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of VEGFA mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of MMP9 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of VEGFA mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] which results in increased uptake of Docetaxel; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] which results in increased uptake of Protein Synthesis Inhibitors
CTD PMID:30041514 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA]; [Docetaxel binds to Chitin] which results in decreased expression of STAT3 mRNA; [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA CTD PMID:30041514 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of VEGFA mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of VEGFA mRNA]; [Docetaxel binds to Chitin] which results in decreased expression of VEGFA mRNA; [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of VEGFA mRNA CTD PMID:30041514 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
N-acetyl-beta-D-glucosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl4 angiopoietin-like 4 increases expression
decreases expression
ISO Acetylglucosamine results in increased expression of ANGPTL4 mRNA
Acetylglucosamine results in decreased expression of ANGPTL4 mRNA
CTD PMID:18047607 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 decreases expression ISO Acetylglucosamine results in decreased expression of AP1S3 mRNA CTD PMID:18047607 NCBI chr 9:85,386,752...85,445,977
Ensembl chr 9:85,387,065...85,445,939
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta decreases expression ISO Acetylglucosamine results in decreased expression of ARHGDIB mRNA CTD PMID:18047607 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 decreases expression ISO Acetylglucosamine results in decreased expression of ARPC4 mRNA CTD PMID:18047607 NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984
JBrowse link
G Calml5 calmodulin-like 5 increases expression ISO Acetylglucosamine results in increased expression of CALML5 mRNA CTD PMID:18047607 NCBI chr17:70,044,956...70,045,886 JBrowse link
G Cat catalase increases expression ISO Acetylglucosamine results in increased expression of CAT mRNA CTD PMID:18047607 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression ISO Acetylglucosamine results in decreased expression of CCT5 mRNA CTD PMID:18047607 NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
JBrowse link
G Cdkl1 cyclin dependent kinase like 1 decreases expression ISO Acetylglucosamine results in decreased expression of CDKL1 mRNA CTD PMID:18047607 NCBI chr 6:92,076,247...92,123,108
Ensembl chr 6:92,077,416...92,121,351
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Acetylglucosamine results in increased expression of CES1 mRNA CTD PMID:18047607 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Dct dopachrome tautomerase increases expression ISO Acetylglucosamine results in increased expression of DCT mRNA CTD PMID:18047607 NCBI chr15:103,208,174...103,245,033
Ensembl chr15:103,208,258...103,244,494
JBrowse link
G Diaph2 diaphanous-related formin 2 decreases expression ISO Acetylglucosamine results in decreased expression of DIAPH2 mRNA CTD PMID:18047607 NCBI chr  X:99,722,910...100,363,228 JBrowse link
G Eno2 enolase 2 increases expression ISO Acetylglucosamine results in increased expression of ENO2 mRNA CTD PMID:18047607 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Fbxo10 F-box protein 10 increases expression ISO Acetylglucosamine results in increased expression of FBXO10 mRNA CTD PMID:18047607 NCBI chr 5:60,589,881...60,636,551
Ensembl chr 5:60,591,023...60,658,564
JBrowse link
G Fbxo4 F-box protein 4 increases expression ISO Acetylglucosamine results in increased expression of FBXO4 mRNA CTD PMID:18047607 NCBI chr 2:53,797,954...53,811,134
Ensembl chr 2:53,797,954...53,811,134
JBrowse link
G Fcnb ficolin B affects binding ISO FCN1 protein binds to Acetylglucosamine CTD PMID:11012776 NCBI chr 3:6,617,816...6,626,193
Ensembl chr 3:6,617,751...6,626,284
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Acetylglucosamine results in increased expression of GPX1 mRNA CTD PMID:18047607 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression ISO Acetylglucosamine results in increased expression of GSTA4 mRNA CTD PMID:18047607 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 increases expression ISO Acetylglucosamine results in increased expression of GSTT2 mRNA CTD PMID:18047607 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G Hk2 hexokinase 2 increases expression ISO Acetylglucosamine results in increased expression of HK2 mRNA CTD PMID:18047607 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Acetylglucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] CTD PMID:16431966 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma increases expression
increases secretion
ISO Acetylglucosamine analog results in increased expression of IFNG mRNA
Acetylglucosamine analog results in increased secretion of IFNG protein
CTD PMID:21349367 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il4 interleukin 4 increases expression ISO Acetylglucosamine analog results in increased expression of IL4 mRNA CTD PMID:21349367 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Klrb1a killer cell lectin-like receptor subfamily B, member 1A affects binding EXP Acetylglucosamine analog binds to KLRB1A protein CTD PMID:21349367 NCBI chr 4:161,950,270...161,966,582
Ensembl chr 4:161,949,817...162,025,187
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO Acetylglucosamine results in decreased expression of ODC1 mRNA CTD PMID:18047607 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 increases expression ISO Acetylglucosamine results in increased expression of PFKFB3 mRNA CTD PMID:18047607 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pon2 paraoxonase 2 increases expression ISO Acetylglucosamine results in increased expression of PON2 mRNA CTD PMID:18047607 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Acetylglucosamine co-treated with Glucose] binds to PPARA protein; Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A decreases expression ISO Acetylglucosamine results in decreased expression of PPP1R9A mRNA CTD PMID:18047607 NCBI chr 4:29,976,485...30,247,371
Ensembl chr 4:29,978,739...30,241,911
JBrowse link
G Prdx3 peroxiredoxin 3 increases expression ISO Acetylglucosamine results in increased expression of PRDX3 mRNA CTD PMID:18047607 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257
JBrowse link
G Prdx5 peroxiredoxin 5 increases expression ISO Acetylglucosamine results in increased expression of PRDX5 mRNA CTD PMID:18047607 NCBI chr 1:222,164,462...222,167,447
Ensembl chr 1:222,164,462...222,167,447
JBrowse link
G Rbp1 retinol binding protein 1 decreases expression
increases expression
ISO Acetylglucosamine results in decreased expression of RBP1 mRNA
Acetylglucosamine results in increased expression of RBP1 mRNA
CTD PMID:18047607 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842
JBrowse link
G Sele selectin E affects binding ISO [Acetylglucosamine analog binds to Biotin] which binds to SELE protein; Acetylglucosamine analog binds to SELE protein CTD PMID:12191509 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Sell selectin L affects binding EXP [Acetylglucosamine analog binds to Biotin] which binds to SELL protein; Acetylglucosamine analog binds to SELL protein CTD PMID:12191509 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Selp selectin P affects binding ISO [Acetylglucosamine analog binds to Biotin] which binds to SELP protein; Acetylglucosamine analog binds to SELP protein CTD PMID:12191509 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpina3m serpin family A member 3M decreases expression ISO Acetylglucosamine results in decreased expression of SERPINA3 mRNA CTD PMID:18047607 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Serpinb3a serpin family B member 3A increases expression ISO Acetylglucosamine results in increased expression of SERPINB4 mRNA CTD PMID:18047607 NCBI chr13:27,153,500...27,159,319
Ensembl chr13:27,153,925...27,158,628
JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression
increases expression
ISO Acetylglucosamine results in decreased expression of SLC2A3 mRNA
Acetylglucosamine results in increased expression of SLC2A3 mRNA
CTD PMID:18047607 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO Acetylglucosamine results in decreased expression of SLC7A5 mRNA CTD PMID:18047607 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Snx5 sorting nexin 5 decreases expression ISO Acetylglucosamine results in decreased expression of SNX5 mRNA CTD PMID:18047607 NCBI chr 3:138,378,032...138,397,944
Ensembl chr 3:138,378,202...138,397,870
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Acetylglucosamine results in decreased expression of SOD2 mRNA CTD PMID:18047607 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tgm5 transglutaminase 5 increases expression ISO Acetylglucosamine results in increased expression of TGM5 mRNA CTD PMID:18047607 NCBI chr 3:112,995,469...113,033,110
Ensembl chr 3:112,995,568...113,023,532
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Acetylglucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] CTD PMID:16431966 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ttll3 tubulin tyrosine ligase like 3 decreases expression ISO Acetylglucosamine results in decreased expression of TTLL3 mRNA CTD PMID:18047607 NCBI chr 4:145,341,059...145,366,614
Ensembl chr 4:145,342,193...145,365,496
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO Acetylglucosamine results in decreased expression of TUBB mRNA CTD PMID:18047607 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Tubgcp3 tubulin, gamma complex associated protein 3 decreases expression ISO Acetylglucosamine results in decreased expression of TUBGCP3 mRNA CTD PMID:18047607 NCBI chr16:82,184,362...82,245,041
Ensembl chr16:82,184,387...82,245,041
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 increases expression ISO Acetylglucosamine results in increased expression of UBE2D3 mRNA CTD PMID:18047607 NCBI chr 2:240,626,198...240,655,874
Ensembl chr 2:240,627,436...240,655,246
JBrowse link
N-acetyl-D-glucosamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Angptl4 angiopoietin-like 4 increases expression
decreases expression
ISO Acetylglucosamine results in increased expression of ANGPTL4 mRNA
Acetylglucosamine results in decreased expression of ANGPTL4 mRNA
CTD PMID:18047607 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ap1s3 adaptor related protein complex 1 subunit sigma 3 decreases expression ISO Acetylglucosamine results in decreased expression of AP1S3 mRNA CTD PMID:18047607 NCBI chr 9:85,386,752...85,445,977
Ensembl chr 9:85,387,065...85,445,939
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta decreases expression ISO Acetylglucosamine results in decreased expression of ARHGDIB mRNA CTD PMID:18047607 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 decreases expression ISO Acetylglucosamine results in decreased expression of ARPC4 mRNA CTD PMID:18047607 NCBI chr 4:145,330,457...145,340,985
Ensembl chr 4:145,330,457...145,340,984
JBrowse link
G Calml5 calmodulin-like 5 increases expression ISO Acetylglucosamine results in increased expression of CALML5 mRNA CTD PMID:18047607 NCBI chr17:70,044,956...70,045,886 JBrowse link
G Cat catalase increases expression ISO Acetylglucosamine results in increased expression of CAT mRNA CTD PMID:18047607 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 decreases expression ISO Acetylglucosamine results in decreased expression of CCT5 mRNA CTD PMID:18047607 NCBI chr 2:84,667,578...84,678,730
Ensembl chr 2:84,667,633...84,678,790
JBrowse link
G Cdkl1 cyclin dependent kinase like 1 decreases expression ISO Acetylglucosamine results in decreased expression of CDKL1 mRNA CTD PMID:18047607 NCBI chr 6:92,076,247...92,123,108
Ensembl chr 6:92,077,416...92,121,351
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Acetylglucosamine results in increased expression of CES1 mRNA CTD PMID:18047607 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Dct dopachrome tautomerase increases expression ISO Acetylglucosamine results in increased expression of DCT mRNA CTD PMID:18047607 NCBI chr15:103,208,174...103,245,033
Ensembl chr15:103,208,258...103,244,494
JBrowse link
G Diaph2 diaphanous-related formin 2 decreases expression ISO Acetylglucosamine results in decreased expression of DIAPH2 mRNA CTD PMID:18047607 NCBI chr  X:99,722,910...100,363,228 JBrowse link
G Eno2 enolase 2 increases expression ISO Acetylglucosamine results in increased expression of ENO2 mRNA CTD PMID:18047607 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Fbxo10 F-box protein 10 increases expression ISO Acetylglucosamine results in increased expression of FBXO10 mRNA CTD PMID:18047607 NCBI chr 5:60,589,881...60,636,551
Ensembl chr 5:60,591,023...60,658,564
JBrowse link
G Fbxo4 F-box protein 4 increases expression ISO Acetylglucosamine results in increased expression of FBXO4 mRNA CTD PMID:18047607 NCBI chr 2:53,797,954...53,811,134
Ensembl chr 2:53,797,954...53,811,134
JBrowse link
G Fcnb ficolin B affects binding ISO FCN1 protein binds to Acetylglucosamine CTD PMID:11012776 NCBI chr 3:6,617,816...6,626,193
Ensembl chr 3:6,617,751...6,626,284
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Acetylglucosamine results in increased expression of GPX1 mRNA CTD PMID:18047607 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression ISO Acetylglucosamine results in increased expression of GSTA4 mRNA CTD PMID:18047607 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 increases expression ISO Acetylglucosamine results in increased expression of GSTT2 mRNA CTD PMID:18047607 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G Hk2 hexokinase 2 increases expression ISO Acetylglucosamine results in increased expression of HK2 mRNA CTD PMID:18047607 NCBI chr 4:113,559,396...113,609,897
Ensembl chr 4:113,559,427...113,610,243
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO Acetylglucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] CTD PMID:16431966 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma increases expression
increases secretion
ISO Acetylglucosamine analog results in increased expression of IFNG mRNA
Acetylglucosamine analog results in increased secretion of IFNG protein
CTD PMID:21349367 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il4 interleukin 4 increases expression ISO Acetylglucosamine analog results in increased expression of IL4 mRNA CTD PMID:21349367 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Klrb1a killer cell lectin-like receptor subfamily B, member 1A affects binding EXP Acetylglucosamine analog binds to KLRB1A protein CTD PMID:21349367 NCBI chr 4:161,950,270...161,966,582
Ensembl chr 4:161,949,817...162,025,187
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO Acetylglucosamine results in decreased expression of ODC1 mRNA CTD PMID:18047607 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 increases expression ISO Acetylglucosamine results in increased expression of PFKFB3 mRNA CTD PMID:18047607 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pon2 paraoxonase 2 increases expression ISO Acetylglucosamine results in increased expression of PON2 mRNA CTD PMID:18047607 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [Acetylglucosamine co-treated with Glucose] binds to PPARA protein; Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] CTD PMID:18812576 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A decreases expression ISO Acetylglucosamine results in decreased expression of PPP1R9A mRNA CTD PMID:18047607 NCBI chr 4:29,976,485...30,247,371
Ensembl chr 4:29,978,739...30,241,911
JBrowse link
G Prdx3 peroxiredoxin 3 increases expression ISO Acetylglucosamine results in increased expression of PRDX3 mRNA CTD PMID:18047607 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257
JBrowse link
G Prdx5 peroxiredoxin 5 increases expression ISO Acetylglucosamine results in increased expression of PRDX5 mRNA CTD PMID:18047607 NCBI chr 1:222,164,462...222,167,447
Ensembl chr 1:222,164,462...222,167,447
JBrowse link
G Rbp1 retinol binding protein 1 decreases expression
increases expression
ISO Acetylglucosamine results in decreased expression of RBP1 mRNA
Acetylglucosamine results in increased expression of RBP1 mRNA
CTD PMID:18047607 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842
JBrowse link
G Sele selectin E affects binding ISO [Acetylglucosamine analog binds to Biotin] which binds to SELE protein; Acetylglucosamine analog binds to SELE protein CTD PMID:12191509 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Sell selectin L affects binding EXP [Acetylglucosamine analog binds to Biotin] which binds to SELL protein; Acetylglucosamine analog binds to SELL protein CTD PMID:12191509 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Selp selectin P affects binding ISO [Acetylglucosamine analog binds to Biotin] which binds to SELP protein; Acetylglucosamine analog binds to SELP protein CTD PMID:12191509 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpina3m serpin family A member 3M decreases expression ISO Acetylglucosamine results in decreased expression of SERPINA3 mRNA CTD PMID:18047607 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Serpinb3a serpin family B member 3A increases expression ISO Acetylglucosamine results in increased expression of SERPINB4 mRNA CTD PMID:18047607 NCBI chr13:27,153,500...27,159,319
Ensembl chr13:27,153,925...27,158,628
JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression
decreases expression
ISO Acetylglucosamine results in increased expression of SLC2A3 mRNA
Acetylglucosamine results in decreased expression of SLC2A3 mRNA
CTD PMID:18047607 NCBI chr 4:155,549,991...155,626,018
Ensembl chr 4:155,408,233...155,631,856
JBrowse link
G Slc7a5 solute carrier family 7 member 5 decreases expression ISO Acetylglucosamine results in decreased expression of SLC7A5 mRNA CTD PMID:18047607 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Snx5 sorting nexin 5 decreases expression ISO Acetylglucosamine results in decreased expression of SNX5 mRNA CTD PMID:18047607 NCBI chr 3:138,378,032...138,397,944
Ensembl chr 3:138,378,202...138,397,870
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression ISO Acetylglucosamine results in decreased expression of SOD2 mRNA CTD PMID:18047607 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tgm5 transglutaminase 5 increases expression ISO Acetylglucosamine results in increased expression of TGM5 mRNA CTD PMID:18047607 NCBI chr 3:112,995,469...113,033,110
Ensembl chr 3:112,995,568...113,023,532
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Acetylglucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] CTD PMID:16431966 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ttll3 tubulin tyrosine ligase like 3 decreases expression ISO Acetylglucosamine results in decreased expression of TTLL3 mRNA CTD PMID:18047607 NCBI chr 4:145,341,059...145,366,614
Ensembl chr 4:145,342,193...145,365,496
JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO Acetylglucosamine results in decreased expression of TUBB mRNA CTD PMID:18047607 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Tubgcp3 tubulin, gamma complex associated protein 3 decreases expression ISO Acetylglucosamine results in decreased expression of TUBGCP3 mRNA CTD PMID:18047607 NCBI chr16:82,184,362...82,245,041
Ensembl chr16:82,184,387...82,245,041
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 increases expression ISO Acetylglucosamine results in increased expression of UBE2D3 mRNA CTD PMID:18047607 NCBI chr 2:240,626,198...240,655,874
Ensembl chr 2:240,627,436...240,655,246
JBrowse link
streptozocin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 increases activity
increases expression
EXP
ISO
Streptozocin results in increased activity of ABCB11 protein
Streptozocin results in increased expression of ABCB11 protein
CTD PMID:12055592, PMID:23319174 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B decreases expression
increases expression
ISO Streptozocin results in decreased expression of ABCB1B mRNA; Streptozocin results in decreased expression of ABCB1B protein
Streptozocin results in increased expression of ABCB1B protein
CTD PMID:22531820, PMID:23319174 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP Streptozocin results in increased expression of ABCB4 mRNA; Streptozocin results in increased expression of ABCB4 protein CTD PMID:12055592 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO Streptozocin results in increased expression of ABCC1 mRNA; Streptozocin results in increased expression of ABCC1 protein CTD PMID:22531820, PMID:23319174 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP
ISO
Streptozocin results in increased expression of ABCC2 mRNA
Streptozocin results in increased expression of ABCC2 mRNA; Streptozocin results in increased expression of ABCC2 protein
CTD PMID:11752103, PMID:22531820, PMID:23319174 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 decreases expression
multiple interactions
increases expression
ISO
EXP
Streptozocin results in decreased expression of ABCC3 mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of ABCC3 mRNA
Streptozocin results in increased expression of ABCC3 mRNA; Streptozocin results in increased expression of ABCC3 protein
CTD PMID:22531820, PMID:23319174, PMID:25905778 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression
multiple interactions
ISO Streptozocin results in increased expression of ABCC4 mRNA; Streptozocin results in increased expression of ABCC4 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of ABCC4 mRNA
CTD PMID:22531820, PMID:23319174, PMID:29382564 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO Streptozocin results in increased expression of ABCC5 mRNA; Streptozocin results in increased expression of ABCC5 protein CTD PMID:22531820, PMID:23319174 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression ISO Streptozocin results in decreased expression of ABCC6 protein CTD PMID:22531820 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Streptozocin results in increased expression of ABCG2 mRNA; Streptozocin results in increased expression of ABCG2 protein CTD PMID:23319174 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression ISO Streptozocin results in increased expression of ABCG5 mRNA CTD PMID:23319174 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Streptozocin results in increased expression of ABCG8 mRNA CTD PMID:23319174 NCBI chr 6:7,961,413...7,980,708
Ensembl chr 6:7,961,413...7,980,708
JBrowse link
G Abhd2 abhydrolase domain containing 2, acylglycerol lipase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ABHD2 mRNA CTD PMID:29127188 NCBI chr 1:140,998,240...141,087,405
Ensembl chr 1:140,998,240...141,087,405
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions
increases expression
decreases expression
decreases activity
EXP Fructose inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Fructose inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]
Streptozocin results in increased expression of ACACA mRNA
CTD PMID:1973097, PMID:28822685 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of ACADM protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACADM protein]
CTD PMID:19634143 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of ACAT1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACAT1 protein]
CTD PMID:19634143 NCBI chr 8:58,166,990...58,195,884
Ensembl chr 8:58,166,990...58,195,884
JBrowse link
G Acbd6 acyl-CoA binding domain containing 6 increases expression EXP Streptozocin results in increased expression of ACBD6 mRNA CTD PMID:25905778 NCBI chr13:73,196,504...73,334,077
Ensembl chr13:73,196,571...73,334,077
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions
increases expression
EXP Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE protein]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE protein]; resveratrol inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE protein]
Streptozocin results in increased expression of ACE mRNA; Streptozocin results in increased expression of ACE protein
CTD PMID:15793251, PMID:16979161, PMID:22191573, PMID:23733546 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of ACE2 protein
ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; ACE2 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]
telmisartan inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]
CTD PMID:20844835, PMID:21381899 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acer2 alkaline ceramidase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of ACER2 mRNA CTD PMID:25905778 NCBI chr 5:105,230,540...105,279,732
Ensembl chr 5:105,230,580...105,279,731
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
increases activity
ISO
EXP
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Alendronate inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Curcumin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Genistein inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Indinavir inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Physostigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]
Streptozocin results in decreased activity of ACHE protein
[Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased activity of ACHE protein; [Propolis co-treated with Streptozocin] inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; [Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein; alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Canagliflozin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Melatonin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Propolis inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; pyrazolanthrone inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Streptozocin inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; Streptozocin promotes the reaction [[Propolis co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Tocotrienols inhibits the reaction [Streptozocin results in increased activity of ACHE protein]
CTD PMID:18208924, PMID:18343489, PMID:19464315, PMID:19705549, PMID:20369229, PMID:20600246, PMID:23060470, PMID:24752916, PMID:27087133, PMID:27566243, PMID:28259689, PMID:28499986, PMID:30120923, PMID:30481507, PMID:31400774 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases activity
increases expression
EXP Streptozocin results in increased activity of ACMSD protein
Streptozocin results in increased expression of ACMSD mRNA
CTD PMID:12042425 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
G Aco2 aconitase 2 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of ACO2 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACO2 protein]
CTD PMID:19634143 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot1 acyl-CoA thioesterase 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT1 mRNA CTD PMID:29127188 NCBI chr 6:107,485,088...107,493,082
Ensembl chr 6:107,485,249...107,493,798
JBrowse link
G Acot2 acyl-CoA thioesterase 2 multiple interactions EXP
ISO
[resveratrol co-treated with Streptozocin] results in decreased expression of ACOT2 mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT2 mRNA
CTD PMID:25905778, PMID:29127188 NCBI chr 6:107,460,596...107,468,324
Ensembl chr 6:107,460,668...107,467,487
JBrowse link
G Acot9 acyl-CoA thioesterase 9 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT9 mRNA CTD PMID:29127188 NCBI chr  X:43,543,069...43,592,200
Ensembl chr  X:43,543,070...43,592,200
JBrowse link
G Acsm2 acyl-CoA synthetase medium-chain family member 2 increases expression EXP Streptozocin results in increased expression of ACSM2 mRNA CTD PMID:25905778 NCBI chr 1:189,289,957...189,329,007
Ensembl chr 1:189,289,957...189,395,276
JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ACSS1 mRNA CTD PMID:29127188 NCBI chr 3:146,420,346...146,470,293
Ensembl chr 3:146,420,346...146,470,293
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP
ISO
2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]; [Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein; Metformin promotes the reaction [2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]]
[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA; [Streptozocin co-treated with fatostatin] results in increased expression of ACTA2 protein; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA]
CTD PMID:29420703, PMID:29988851, PMID:30551545 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actc1 actin, alpha, cardiac muscle 1 decreases expression EXP Streptozocin results in decreased expression of ACTC1 protein CTD PMID:21136691 NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
JBrowse link
G Actn4 actinin alpha 4 increases expression
multiple interactions
EXP Streptozocin results in increased expression of ACTN4 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ACTN4 protein]
CTD PMID:19634143 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Acy1 aminoacylase 1 multiple interactions
decreases expression
EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of ACY1 protein] CTD PMID:19634143 NCBI chr 8:115,134,792...115,140,171
Ensembl chr 8:115,134,765...115,140,080
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 multiple interactions
increases expression
EXP
ISO
stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of ADGRE1 protein]]
Streptozocin results in increased expression of ADGRE1 mRNA
[fatostatin co-treated with Streptozocin] results in increased expression of ADGRE1 mRNA
CTD PMID:23611540, PMID:29420703 NCBI chr 9:9,431,888...9,585,883
Ensembl chr 9:9,431,860...9,585,865
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression EXP Streptozocin results in increased expression of ADH1 mRNA CTD PMID:25905778 NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
decreases expression
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein]; Omaveloxolone analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]
Streptozocin results in decreased expression of ADIPOQ mRNA; Streptozocin results in decreased expression of ADIPOQ protein
CTD PMID:17270171, PMID:21439372, PMID:21912612, PMID:22675305, PMID:24854284, PMID:27488359, PMID:28178614, PMID:29988851, PMID:32410268 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adipor1 adiponectin receptor 1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of ADIPOR1 protein
resveratrol inhibits the reaction [Streptozocin results in decreased expression of ADIPOR1 protein]
CTD PMID:17270171, PMID:24413998 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions
decreases expression
EXP Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] CTD PMID:21912612 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adora2a adenosine A2a receptor increases expression ISO Streptozocin results in increased expression of ADORA2A protein CTD PMID:26654777 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adra1a adrenoceptor alpha 1A increases expression EXP Streptozocin results in increased expression of ADRA1A mRNA; Streptozocin results in increased expression of ADRA1A protein CTD PMID:19133277 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra1b adrenoceptor alpha 1B increases expression EXP Streptozocin results in increased expression of ADRA1B mRNA CTD PMID:19298542 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Adra1d adrenoceptor alpha 1D decreases expression EXP Streptozocin results in decreased expression of ADRA1D mRNA CTD PMID:19298542 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566
JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
decreases expression
EXP Metoprolol inhibits the reaction [Streptozocin results in decreased expression of ADRB1 protein] CTD PMID:18703049 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression
multiple interactions
EXP Streptozocin results in increased expression of ADRB2 protein
Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB2 protein]
CTD PMID:18703049 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions
increases expression
EXP Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB3 protein] CTD PMID:18703049 NCBI chr16:69,003,541...69,006,632
Ensembl chr16:69,003,868...69,006,632
JBrowse link
G Afmid arylformamidase increases expression EXP Streptozocin results in increased expression of AFMID mRNA CTD PMID:25905778 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Afp alpha-fetoprotein multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of AFP mRNA CTD PMID:29127188 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Ager advanced glycosylation end product-specific receptor increases expression
increases response to substance
multiple interactions
EXP
ISO
Streptozocin results in increased expression of AGER mRNA; Streptozocin results in increased expression of AGER protein
AGER protein results in increased susceptibility to Streptozocin
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of AGER mRNA]
Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of AGER protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of AGER mRNA]
CTD PMID:19397970, PMID:19833897, PMID:22476978, PMID:25199697, PMID:27109771, PMID:31009641 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agrp agouti related neuropeptide multiple interactions
increases expression
EXP INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA] CTD PMID:20219977 NCBI chr19:37,525,941...37,584,875
Ensembl chr19:37,526,419...37,528,011
JBrowse link
G Agt angiotensinogen multiple interactions
increases expression
ISO
EXP
IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]
Streptozocin results in increased expression of AGT mRNA; Streptozocin results in increased expression of AGT protein
Streptozocin results in increased expression of AGT mRNA; Streptozocin results in increased expression of AGT protein; Streptozocin results in increased expression of AGT protein modified form
ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; AGT protein modified form inhibits the reaction [Streptozocin results in decreased abundance of Cyclic GMP]; AGT protein modified form inhibits the reaction [Streptozocin results in increased expression of PDE5 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGT protein]
CTD PMID:11375343, PMID:15643138, PMID:17724226, PMID:18487452, PMID:20547220, PMID:20844835, PMID:28299329 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
increases expression
ISO
EXP
telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA]
Streptozocin results in increased expression of AGTR1A mRNA; Streptozocin results in increased expression of AGTR1A protein
CTD PMID:17724226, PMID:18487452, PMID:21381899, PMID:28946194 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr2 angiotensin II receptor, type 2 increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of AGTR2 mRNA; Streptozocin results in increased expression of AGTR2 protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; esculetin promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA]
CTD PMID:15587404, PMID:17724226, PMID:28946194 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 multiple interactions
decreases expression
EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of AGXT2 protein] CTD PMID:19634143 NCBI chr 2:60,337,667...60,379,144
Ensembl chr 2:60,337,667...60,379,420
JBrowse link
G Ahcy adenosylhomocysteinase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of AHCY mRNA; [Streptozocin co-treated with Dietary Fats] results in increased methylation of AHCY gene CTD PMID:29127188 NCBI chr 3:150,587,833...150,603,057
Ensembl chr 3:150,587,833...150,603,082
JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression ISO Streptozocin results in decreased expression of AHR mRNA CTD PMID:22531820 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of AIFM1 protein
[Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of AIFM1 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1]
Trientine inhibits the reaction [Streptozocin results in increased expression of AIFM1 protein]
CTD PMID:19634143, PMID:23458895, PMID:23499715 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Ak4 adenylate kinase 4 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of AK4 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of AK4 protein]
CTD PMID:19634143 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 increases expression
multiple interactions
EXP Streptozocin results in increased expression of AKR1A1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of AKR1A1 protein]
CTD PMID:19634143 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions ISO Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK9 protein] CTD PMID:25541468 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions EXP
ISO
[resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of AKR1C18 mRNA
CTD PMID:25905778, PMID:29127188 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP Streptozocin results in increased expression of AKR7A3 mRNA CTD PMID:25905778 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases phosphorylation
decreases expression
EXP
ISO
[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein; [Resveratrol co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]
Streptozocin results in decreased expression of AKT1 mRNA; Streptozocin results in decreased expression of AKT1 protein
CTD PMID:16595661, PMID:19002579, PMID:22675305, PMID:24810525, PMID:25541178, PMID:26071184, PMID:27417257, PMID:31743741, PMID:31877369 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein] CTD PMID:27270450 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO [Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein; alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein] CTD PMID:7728901 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of ALAS1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA]
CTD PMID:16684804 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alb albumin multiple interactions
increases expression
decreases expression
increases secretion
ISO
EXP
[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein]; TXN protein inhibits the reaction [Streptozocin results in increased secretion of ALB protein]
Streptozocin results in increased expression of ALB protein
Streptozocin results in decreased expression of ALB protein
[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein; [Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein; Curcumin inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein]; LR-90 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of ALB protein]
CTD PMID:12845431, PMID:14871415, PMID:17360766, PMID:18204486, PMID:21450970, PMID:24923654, PMID:25199697, PMID:25240712, PMID:29331653, PMID:31063766 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Streptozocin results in increased expression of ALDH1A1 mRNA CTD PMID:25905778 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member increases expression
multiple interactions
decreases expression
EXP Streptozocin results in increased expression of ALDH2 protein
Ethanol inhibits the reaction [Streptozocin results in decreased expression of ALDH2]
Streptozocin results in decreased expression of ALDH2 mRNA; Streptozocin results in decreased expression of ALDH2 protein
CTD PMID:21136691, PMID:23500772 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression
multiple interactions
EXP Streptozocin results in increased expression of ALDOB protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ALDOB protein]
CTD PMID:19634143 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Alkbh3 alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of ALKBH3 mRNA CTD PMID:20665664 NCBI chr 3:82,874,242...82,907,467
Ensembl chr 3:82,874,248...82,906,581
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ALOX5AP mRNA CTD PMID:29127188 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Alpk1 alpha-kinase 1 multiple interactions
increases response to substance
ISO [ALPK1 protein results in increased susceptibility to Streptozocin] which results in decreased expression of PRKG2 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 protein; ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein]; ALPK1 protein promotes the reaction [Streptozocin results in increased abundance of Blood Glucose] CTD PMID:27542954 NCBI chr 2:231,997,360...232,117,471
Ensembl chr 2:231,996,088...232,117,134
JBrowse link
G Angpt1 angiopoietin 1 increases expression
decreases expression
EXP Streptozocin results in increased expression of ANGPT1 mRNA; Streptozocin results in increased expression of ANGPT1 protein
Streptozocin results in decreased expression of ANGPT1 mRNA
CTD PMID:15643138, PMID:19958114 NCBI chr 7:81,338,327...81,592,459
Ensembl chr 7:81,342,280...81,592,206
JBrowse link
G Angpt2 angiopoietin 2 multiple interactions
increases expression
EXP Enalapril inhibits the reaction [Streptozocin results in increased expression of ANGPT2 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of ANGPT2 protein]
Streptozocin results in increased expression of ANGPT2 mRNA; Streptozocin results in increased expression of ANGPT2 protein
CTD PMID:15643138, PMID:19958114, PMID:20821229 NCBI chr16:75,966,480...76,016,147
Ensembl chr16:75,966,352...76,016,195
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of ANGPTL4 mRNA CTD PMID:25905778 NCBI chr 7:18,627,814...18,634,043
Ensembl chr 7:18,627,808...18,634,079
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression
multiple interactions
EXP Streptozocin results in increased expression of ANKRD1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ANKRD1 mRNA]
CTD PMID:16684804 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Anpep alanyl aminopeptidase, membrane decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of ANPEP protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ANPEP protein]
CTD PMID:19634143 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Anxa3 annexin A3 increases expression
multiple interactions
EXP Streptozocin results in increased expression of ANXA3 protein
[resveratrol co-treated with Streptozocin] results in increased expression of ANXA3 mRNA; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA3 protein]
CTD PMID:21136691, PMID:25905778 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Anxa5 annexin A5 decreases expression
multiple interactions
increases expression
EXP Streptozocin results in decreased expression of ANXA5 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ANXA5 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA5 protein]
CTD PMID:19634143, PMID:21136691 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance ISO APEX1 protein mutant form results in increased susceptibility to Streptozocin CTD PMID:19470598 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions
increases expression
EXP Trientine inhibits the reaction [Streptozocin results in increased expression of APOA1 protein] CTD PMID:19634143 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoa4 apolipoprotein A4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of APOA4 mRNA CTD PMID:25905778 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoe apolipoprotein E increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of APOE mRNA
[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of APOE mRNA]
CTD PMID:16380481, PMID:16684804 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases expression
EXP
ISO
Memantine inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]
Alendronate inhibits the reaction [Streptozocin results in increased expression of APP protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of APP protein]
Streptozocin results in increased expression of APP mRNA; Streptozocin results in increased expression of APP protein
CTD PMID:21069392, PMID:21290839, PMID:30481507 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp1 aquaporin 1 multiple interactions
decreases expression
EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of AQP1 protein] CTD PMID:19634143 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqp7 aquaporin 7 increases expression
multiple interactions
EXP Streptozocin results in increased expression of AQP7 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of AQP7 mRNA]
CTD PMID:16684804 NCBI chr 5:57,358,297...57,372,332
Ensembl chr 5:57,358,327...57,372,239
JBrowse link
G Aqp9 aquaporin 9 increases expression EXP Streptozocin results in increased expression of AQP9 protein CTD PMID:22114114 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Arg1 arginase 1 multiple interactions
increases expression
ISO [NTN1 protein co-treated with Streptozocin] results in increased expression of ARG1 protein; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]
Streptozocin results in increased expression of ARG1 protein
CTD PMID:29059224, PMID:29673160 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of ARHGAP9 mRNA CTD PMID:25905778 NCBI chr 7:70,612,650...70,620,900
Ensembl chr 7:70,612,103...70,620,890
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ARNTL mRNA CTD PMID:29127188 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of ASNS mRNA CTD PMID:25905778 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atf2 activating transcription factor 2 increases expression
multiple interactions
EXP Streptozocin results in increased expression of ATF2 protein
resveratrol inhibits the reaction [Streptozocin results in increased expression of ATF2 protein]
CTD PMID:26499206 NCBI chr 3:60,721,137...60,795,951
Ensembl chr 3:60,721,135...60,795,951
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases phosphorylation
increases expression
ISO
EXP
sulforafan inhibits the reaction [Streptozocin results in increased expression of ATF4 protein]
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased phosphorylation of ATF4 protein]
CTD PMID:24967692, PMID:30980806 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf5 activating transcription factor 5 decreases expression EXP Streptozocin results in decreased expression of ATF5 mRNA CTD PMID:25905778 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atf6 activating transcription factor 6 increases cleavage
multiple interactions
EXP Streptozocin results in increased cleavage of ATF6 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of ATF6 protein]
CTD PMID:30980806 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atg12 autophagy related 12 increases expression ISO Streptozocin results in increased expression of ATG12 mRNA CTD PMID:24889822 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atg5 autophagy related 5 increases expression ISO Streptozocin results in increased expression of ATG5 mRNA CTD PMID:24889822 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atox1 antioxidant 1 copper chaperone decreases expression EXP Streptozocin results in decreased expression of ATOX1 protein CTD PMID:24927960 NCBI chr10:40,790,850...40,805,886
Ensembl chr10:40,790,845...40,805,941
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases activity
decreases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased activity of ATP2A2 protein
Streptozocin results in decreased expression of ATP2A2 mRNA
[bisphenol A co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [Ethinyl Estradiol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA
CTD PMID:16685413, PMID:29935216 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO [Streptozocin co-treated with bisphenol A] results in decreased expression of ATP2A3 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of ATP2A3 mRNA CTD PMID:29935216 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions
increases expression
ISO [Streptozocin co-treated with bisphenol A] results in increased expression of ATP2B1 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of ATP2B1 mRNA
Streptozocin results in increased expression of ATP2B1 mRNA
CTD PMID:29935216 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha increases expression
multiple interactions
EXP Streptozocin results in increased expression of ATP5F1A protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1A protein]
CTD PMID:21136691 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression
multiple interactions
EXP Streptozocin results in increased expression of ATP5F1B protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1B protein]
CTD PMID:21136691 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5mf ATP synthase membrane subunit f affects expression
multiple interactions
increases expression
ISO
EXP
Streptozocin affects the expression of ATP5J2 mRNA
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5MF protein]
CTD PMID:18583417, PMID:19634143 NCBI chr12:11,191,799...11,198,369
Ensembl chr12:11,191,812...11,198,369
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP increases expression
multiple interactions
EXP Streptozocin results in increased expression of ATP5PO protein
Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5PO protein]
CTD PMID:19634143 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 multiple interactions
increases expression
EXP (3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; (3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein]
Streptozocin results in increased expression of ATP6AP2 mRNA; Streptozocin results in increased expression of ATP6AP2 protein
CTD PMID:18192338 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions
decreases expression
ISO ATP7A gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; ATP7A protein inhibits the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein] CTD PMID:23884884 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Atp7b ATPase copper transporting beta decreases expression EXP Streptozocin results in decreased expression of ATP7B protein CTD PMID:24927960 NCBI chr16:74,865,516...74,944,935
Ensembl chr16:74,865,516...74,945,286
JBrowse link
G Avp arginine vasopressin multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA] CTD PMID:32303808 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression EXP Streptozocin results in increased expression of AXL protein CTD PMID:12644472 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G B3galnt1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of B3GALNT1 mRNA CTD PMID:25905778 NCBI chr 2:166,226,736...166,255,978
Ensembl chr 2:166,226,754...166,255,302
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of BAAT mRNA CTD PMID:29382564 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Bace1 beta-secretase 1 multiple interactions
increases expression
ISO Alendronate inhibits the reaction [Streptozocin results in increased expression of BACE1 protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of BACE1 protein] CTD PMID:30481507 NCBI chr 8:50,140,092...50,162,388
Ensembl chr 8:50,139,997...50,162,361
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases expression
decreases expression
EXP Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BAD protein modified form]; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAD protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BAD protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of BAD protein
Streptozocin results in decreased expression of BAD protein; Streptozocin results in decreased expression of BAD protein modified form
CTD PMID:15976052, PMID:19682444, PMID:28856781 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAK1 protein] CTD PMID:28856781 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects expression
increases expression
ISO
EXP
IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of BAX protein]; sulforafan inhibits the reaction [Streptozocin results in increased expression of BAX protein]
Streptozocin affects the expression of BAX protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Diazoxide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of BAX protein]; ferulic acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of BAX]; Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of BAX protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX protein]
Streptozocin results in increased expression of BAX; Streptozocin results in increased expression of BAX mRNA; Streptozocin results in increased expression of BAX protein
CTD PMID:11375343, PMID:18758938, PMID:19931367, PMID:20574430, PMID:20650802, PMID:22429817, PMID:23267840, PMID:24954035, PMID:24967692, PMID:25191525, PMID:25301743, PMID:25541178, PMID:27702591, PMID:29953732, PMID:30611788, PMID:30980806, PMID:31009641, PMID:31029786, PMID:31323227 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B affects expression ISO Streptozocin affects the expression of BAZ1B mRNA CTD PMID:26073000 NCBI chr12:24,478,882...24,536,851
Ensembl chr12:24,478,898...24,537,313
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of BBOX1 mRNA CTD PMID:25905778 NCBI chr 3:101,425,684...101,474,848
Ensembl chr 3:101,427,055...101,474,890
JBrowse link
G Bche butyrylcholinesterase multiple interactions
increases activity
ISO Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of BCHE protein] CTD PMID:27087133, PMID:30481507 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha affects expression ISO Streptozocin affects the expression of BCKDHA mRNA CTD PMID:18583417 NCBI chr 1:82,423,291...82,452,094
Ensembl chr 1:82,423,277...82,452,281
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
affects expression
multiple interactions
decreases expression
EXP
ISO
Streptozocin results in increased expression of BCL2 protein
Streptozocin affects the expression of BCL2 protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]]; 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; [Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BCL2 protein]; Diazoxide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; fasudil inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Propofol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of BCL2 protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]
[Streptozocin co-treated with bisphenol A] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of BCL2 mRNA; bisphenol A promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ethinyl Estradiol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; montelukast inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; octylphenol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of BCL2 protein]
Streptozocin results in decreased expression of BCL2 mRNA; Streptozocin results in decreased expression of BCL2 protein
CTD PMID:15056984, PMID:15587404, PMID:15976052, PMID:16909474, PMID:18758938, PMID:19682444, PMID:20574430, PMID:20650802, PMID:22429817, PMID:24781736, PMID:24810525, PMID:24954035, PMID:25301743, PMID:25541178, PMID:25665769, PMID:27702591, PMID:28856781, PMID:29953732, PMID:30611788, PMID:31009641, PMID:31323227 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of BCL2A1 mRNA CTD PMID:25905778 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of BCL2L1 protein
Streptozocin results in decreased expression of BCL2L1 mRNA
Streptozocin results in decreased expression of BCL2L1 protein
Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2L1 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]]
CTD PMID:15976052, PMID:16595661, PMID:18758938, PMID:19682444, PMID:24781736, PMID:28856781 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl3 BCL3, transcription coactivator multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of BCL3 mRNA CTD PMID:25905778 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Bdh1 3-hydroxybutyrate dehydrogenase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of BDH1 mRNA CTD PMID:25905778 NCBI chr11:72,577,547...72,619,435
Ensembl chr11:72,578,533...72,614,176
JBrowse link
G Bdkrb1 bradykinin receptor B1 increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of BDKRB1 mRNA
[HOE 140, desArg(10)- binds to and results in decreased activity of BDKRB1 protein] which results in decreased susceptibility to Streptozocin
CTD PMID:17989505, PMID:19516248 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of BDKRB2 mRNA
[icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Streptozocin
CTD PMID:17989505, PMID:19516248 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Becn1 beclin 1 increases expression ISO Streptozocin results in increased expression of BECN1 mRNA; Streptozocin results in increased expression of BECN1 protein CTD PMID:24889822 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bglap bone gamma-carboxyglutamate protein decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of BGLAP mRNA; Streptozocin results in decreased expression of BGLAP protein
[Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form]
CTD PMID:25617479, PMID:27488359 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase increases activity
multiple interactions
increases expression
EXP
ISO
Streptozocin results in increased activity of BHMT protein
[Streptozocin co-treated with Dietary Fats] affects the expression of BHMT mRNA
Streptozocin results in increased expression of BHMT mRNA
CTD PMID:16835399, PMID:29127188 NCBI chr 2:23,236,573...23,256,158
Ensembl chr 2:23,236,575...23,256,158
JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of BMP6 mRNA
esculetin inhibits the reaction [Streptozocin results in decreased expression of BMP6 mRNA]
CTD PMID:21450970 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmp7 bone morphogenetic protein 7 increases expression
affects expression
EXP Streptozocin results in increased expression of BMP7 protein
Streptozocin affects the expression of BMP7 mRNA
CTD PMID:17437042 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G C1qa complement C1q A chain multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of C1QA mRNA CTD PMID:25905778 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G C1qb complement C1q B chain increases expression
multiple interactions
EXP Streptozocin results in increased expression of C1QB mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of C1QB mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C1QB mRNA]
CTD PMID:16684804, PMID:25905778 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G C1qc complement C1q C chain multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of C1QC mRNA CTD PMID:25905778 NCBI chr 5:155,255,013...155,258,631
Ensembl chr 5:155,255,005...155,258,392
JBrowse link
G C4b complement C4B (Chido blood group) increases expression
multiple interactions
EXP Streptozocin results in increased expression of C4B mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C4B mRNA]
CTD PMID:16684804 NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
JBrowse link
G Ca3 carbonic anhydrase 3 multiple interactions
decreases expression
EXP [resveratrol co-treated with Streptozocin] results in decreased expression of CAR3 mRNA
Streptozocin results in decreased expression of CAR3 mRNA
CTD PMID:25905778 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C multiple interactions
increases expression
ISO [bisphenol A co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA
Streptozocin results in increased expression of CACNA1C mRNA
CTD PMID:29935216 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Calca calcitonin-related polypeptide alpha decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CALCA protein
Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; capsazepine inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; RN 1734 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; U 0126 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]
CTD PMID:30583000 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calm1 calmodulin 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein] CTD PMID:32303808 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm3 calmodulin 3 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CALM3 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CALM3 protein]
CTD PMID:19634143 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Calr calreticulin decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CALR protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CALR protein]
CTD PMID:19634143 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
decreases expression
ISO
EXP
myristoylated autocamtide-2-related inhibitory peptide inhibits the reaction [Streptozocin results in increased phosphorylation of CAMK2A protein]; resveratrol inhibits the reaction [Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein
Streptozocin results in decreased expression of CAMK2A mRNA; Streptozocin results in decreased expression of CAMK2A protein
Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein]
CTD PMID:20424226, PMID:24333387 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Capg capping actin protein, gelsolin like multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CAPG mRNA CTD PMID:25905778 NCBI chr 4:100,395,693...100,419,447
Ensembl chr 4:100,407,658...100,419,446
JBrowse link
G Cartpt CART prepropeptide decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CARTPT mRNA
GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA]
CTD PMID:20219977 NCBI chr 2:30,125,249...30,127,408
Ensembl chr 2:30,125,249...30,127,269
JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression
EXP
ISO
Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein
[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein]
Streptozocin results in increased expression of CASP1 mRNA; Streptozocin results in increased expression of CASP1 protein
CTD PMID:23647015, PMID:27783111, PMID:32202043 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 increases expression
multiple interactions
increases cleavage
ISO
EXP
Streptozocin results in increased expression of CASP12 protein modified form
Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]
FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; sulforafan inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein]
CTD PMID:23499715, PMID:24967692, PMID:25541178 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
increases cleavage
decreases cleavage
EXP
ISO
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; ferulic acid analog inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Memantine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Propofol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP3 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]
Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein modified form
[Streptozocin co-treated with bisphenol A] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with octylphenol] results in increased expression of CASP3 mRNA; fatostatin promotes the reaction [Streptozocin results in increased cleavage of CASP3 protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; NTN1 protein inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of CASP3 mRNA]; sulforafan inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]
Streptozocin analog results in increased activity of CASP3 protein; Streptozocin results in increased activity of CASP3 protein
CTD PMID:12502508, PMID:15976052, PMID:18721751, PMID:18758938, PMID:19133311, PMID:19682444, PMID:19840221, PMID:19931367, PMID:19951573, PMID:20053369, PMID:20224876, PMID:20424226, PMID:20654064, PMID:21599458, PMID:23267840, PMID:23453443, PMID:23458895, PMID:24333387, PMID:24810525, PMID:24967692, PMID:25541178, PMID:25665769, PMID:26499206, PMID:26887929, PMID:27702591, PMID:28856781, PMID:29059224, PMID:29420703, PMID:29935216, PMID:30980806, PMID:31029786, PMID:31323227 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 increases expression EXP Streptozocin results in increased expression of CASP6 protein CTD PMID:15976052 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 increases expression
multiple interactions
EXP Streptozocin results in increased expression of CASP7 protein
2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]; [Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; Metformin promotes the reaction [2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]
CTD PMID:15976052, PMID:30551545 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
increases expression
EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]
Streptozocin results in increased expression of CASP8 mRNA; Streptozocin results in increased expression of CASP8 protein
CTD PMID:23267840, PMID:25541178, PMID:28856781 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases expression
EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP9 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]
Streptozocin results in increased activity of CASP9 protein
CTD PMID:15976052, PMID:19951573, PMID:22940631, PMID:28856781 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase increases expression
decreases activity
increases activity
multiple interactions
decreases expression
increases phosphorylation
decreases response to substance
ISO
EXP
Streptozocin results in increased expression of CAT mRNA
Streptozocin results in decreased activity of CAT protein
Streptozocin results in increased activity of CAT protein
2-hydroxy-4-methoxy benzoic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 5,3'-dihydroxy-3,6,7,4',5'-pentamethoxyflavone inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT protein; [Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of CAT protein; [Propolis co-treated with Streptozocin] results in increased activity of CAT protein; [Quercetin co-treated with coenzyme Q10] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Quercetin co-treated with Streptozocin] results in increased activity of CAT protein; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein; [Streptozocin co-treated with Isoproterenol] affects the activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased activity of CAT protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; corilagin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; crocin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Diltiazem inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Diosmin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Losartan inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Melatonin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; naringenin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; palbinone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; pinitol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein]; Propolis inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Resveratrol promotes the reaction [Streptozocin results in decreased expression of CAT mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Saponins inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Streptozocin inhibits the reaction [Lipopolysaccharides results in increased expression of CAT protein]; Streptozocin inhibits the reaction [Streptozocin results in increased expression of CAT protein]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of CAT protein]; Streptozocin results in decreased expression of and results in decreased activity of CAT protein; Streptozocin results in increased expression of and results in increased activity of CAT protein; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Tocotrienols inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; U 78517F inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
Streptozocin results in decreased expression of CAT mRNA; Streptozocin results in decreased expression of CAT protein
[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of CAT mRNA; Alendronate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Donepezil inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of CAT]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; sulforafan inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; sulforafan inhibits the reaction [Streptozocin results in decreased expression of CAT protein]
Streptozocin results in decreased expression of CAT; Streptozocin results in decreased expression of CAT mRNA
Streptozocin results in increased phosphorylation of CAT protein
CAT protein results in decreased susceptibility to Streptozocin
CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Streptozocin]; SOD2 protein promotes the reaction [CAT protein results in decreased susceptibility to Streptozocin]
CTD PMID:9522273, PMID:11424224, PMID:12123627, PMID:12242689, PMID:15298345, PMID:15821039, PMID:15855331, PMID:15957552, PMID:16177186, PMID:16581090, PMID:16780994, PMID:17042909, PMID:17145126, PMID:18779489, PMID:19133311, PMID:19464315, PMID:19682444, PMID:19840221, PMID:19931367, PMID:20053369, PMID:20307516, PMID:20643114, PMID:20691780, PMID:20828602, PMID:20951120, PMID:21382363, PMID:21439372, PMID:21457706, PMID:21630391, PMID:22056647, PMID:22476978, PMID:22733486, PMID:23122718, PMID:23677724, PMID:23716880, PMID:24740756, PMID:24752916, PMID:24760747, PMID:24854284, PMID:24877639, PMID:24954035, PMID:24967692, PMID:25057273, PMID:25362599, PMID:25503068, PMID:25617480, PMID:25986969, PMID:26286521, PMID:26341651, PMID:26499206, PMID:26690102, PMID:26700463, PMID:26748309, PMID:27350165, PMID:28178614, PMID:28757134, PMID:29223569, PMID:29247773, PMID:29331653, PMID:29409856, PMID:29988851, PMID:30144451, PMID:30481507, PMID:30582900, PMID:30817903, PMID:30958922, PMID:31009641, PMID:31100278, PMID:31400774, PMID:31682803, PMID:32202043, PMID:32662907 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 multiple interactions
increases expression
EXP resveratrol inhibits the reaction [Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]]; resveratrol inhibits the reaction [Streptozocin results in increased expression of CAV1 protein]; Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein] CTD PMID:18266981 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cav3 caveolin 3 multiple interactions
decreases expression
EXP resveratrol inhibits the reaction [Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAV3 protein]; Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein] CTD PMID:18266981 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Cbr1 carbonyl reductase 1 decreases activity EXP Streptozocin results in decreased activity of CBR1 protein CTD PMID:11057757 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Cbs cystathionine beta synthase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CBS mRNA CTD PMID:29127188 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects response to substance
increases secretion
multiple interactions
increases expression
ISO
EXP
CCL2 affects the susceptibility to Streptozocin
Streptozocin results in increased secretion of CCL2 protein
4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein; [fatostatin co-treated with Streptozocin] results in increased expression of CCL2 protein; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]]
2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein; Flavonoids inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; prolinedithiocarbamate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]
Streptozocin results in increased expression of CCL2 mRNA; Streptozocin results in increased expression of CCL2 protein
Streptozocin results in increased expression of CCL2; Streptozocin results in increased expression of CCL2 mRNA; Streptozocin results in increased expression of CCL2 protein
CTD PMID:15284299, PMID:16374426, PMID:16684804, PMID:17624267, PMID:18413206, PMID:18999900, PMID:19921414, PMID:21832210, PMID:23611540, PMID:24513509, PMID:25199697, PMID:27769711, PMID:29420703, PMID:29988851, PMID:30551545, PMID:31696645 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Streptozocin results in increased expression of CCL5 mRNA CTD PMID:29420703 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CCL6 mRNA CTD PMID:25905778 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of CCN2; Streptozocin results in increased expression of CCN2 protein
Streptozocin results in increased expression of CCN2 mRNA; Streptozocin results in increased expression of CCN2 protein
[Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein; sulforafan inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein]; sulforafan inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; idebenone inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]
CTD PMID:10026205, PMID:14586741, PMID:17270171, PMID:19369054, PMID:19657322, PMID:19895808, PMID:21416479, PMID:24707343, PMID:24967692, PMID:25057273, PMID:28648635, PMID:31062909 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccnt1 cyclin T1 multiple interactions EXP [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] CTD PMID:20828602 NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723
JBrowse link
G Ccs copper chaperone for superoxide dismutase decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CCS mRNA; Streptozocin results in decreased expression of CCS protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS protein]
CTD PMID:24927960 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404
JBrowse link
G Cd14 CD14 molecule multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CD14 mRNA CTD PMID:29127188 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd163 CD163 molecule multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD163 mRNA CTD PMID:25905778 NCBI chr 4:156,752,063...156,785,467
Ensembl chr 4:156,752,082...156,785,467
JBrowse link
G Cd200r1l CD200 receptor 1-like multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD200R1L mRNA CTD PMID:25905778 NCBI chr11:60,803,856...60,828,979
Ensembl chr11:60,804,311...60,819,249
JBrowse link
G Cd24 CD24 molecule multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CD24A mRNA CTD PMID:29127188 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CD36 mRNA CTD PMID:29127188 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd53 Cd53 molecule multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD53 mRNA CTD PMID:25905778 NCBI chr 2:209,489,279...209,537,098
Ensembl chr 2:209,489,279...209,537,087
JBrowse link
G Cd5l Cd5 molecule-like multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD5L mRNA CTD PMID:25905778 NCBI chr 2:186,685,104...186,696,117
Ensembl chr 2:186,685,104...186,696,117
JBrowse link
G Cd68 Cd68 molecule multiple interactions
increases expression
EXP [resveratrol co-treated with Streptozocin] results in increased expression of CD68 mRNA; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of CD68 protein] CTD PMID:25905778, PMID:29291386 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd80 Cd80 molecule multiple interactions
increases expression
ISO Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD80 protein] CTD PMID:15892581 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd86 CD86 molecule multiple interactions
increases expression
ISO
EXP
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD86 protein]
[resveratrol co-treated with Streptozocin] results in increased expression of CD86 mRNA
CTD PMID:15892581, PMID:25905778 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdh1 cadherin 1 decreases expression EXP Streptozocin results in decreased expression of CDH1 CTD PMID:32469605 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of CDH2 protein
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CDH2 protein]
CTD PMID:31682803 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdk9 cyclin-dependent kinase 9 multiple interactions EXP [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein] CTD PMID:20828602 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO
EXP
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; [Streptozocin co-treated with Dietary Fats] results in increased expression of CDKN1A mRNA; Quercetin inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN1A]
Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of CDKN1A protein]; Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter]
Streptozocin results in increased expression of CDKN1A mRNA; Streptozocin results in increased expression of CDKN1A protein
Streptozocin results in increased expression of CDKN1A; Streptozocin results in increased expression of CDKN1A mRNA
CTD PMID:19496084, PMID:22744176, PMID:25301743, PMID:27652271, PMID:29127188, PMID:29673160 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions
ISO Streptozocin results in increased expression of CDKN2A mRNA; Streptozocin results in increased expression of CDKN2A protein
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]
CTD PMID:29059224, PMID:29673160 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CEBPD mRNA CTD PMID:25905778 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Ces2c carboxylesterase 2C multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CES2C mRNA CTD PMID:25905778 NCBI chr 1:282,640,752...282,648,319
Ensembl chr 1:282,638,017...282,702,424
JBrowse link
G Cfd complement factor D increases expression EXP Streptozocin results in increased expression of CFD mRNA CTD PMID:3299706 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Cfl1 cofilin 1 multiple interactions
increases phosphorylation
EXP fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of CFL1 protein] CTD PMID:22062134 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cfp complement factor properdin multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CFP mRNA CTD PMID:25905778 NCBI chr  X:1,311,121...1,316,683
Ensembl chr  X:1,311,121...1,316,682
JBrowse link
G Chat choline O-acetyltransferase multiple interactions
affects localization
EXP Inositol inhibits the reaction [Streptozocin affects the localization of CHAT protein] CTD PMID:2431858 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chka choline kinase alpha multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CHKA mRNA CTD PMID:29127188 NCBI chr 1:219,076,618...219,126,221
Ensembl chr 1:219,077,771...219,126,220
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions
increases expression
affects expression
EXP 1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein]
Streptozocin results in increased expression of CHRM2 mRNA; Streptozocin results in increased expression of CHRM2 protein
CTD PMID:17989502, PMID:18715473 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions
affects expression
EXP 1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM3 mRNA] CTD PMID:17989502 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
increases expression
EXP Quercetin inhibits the reaction [Streptozocin results in increased expression of CHUK protein] CTD PMID:16177186 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Cidea cell death-inducing DFFA-like effector a multiple interactions EXP
ISO
[resveratrol co-treated with Streptozocin] results in increased expression of CIDEA mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of CIDEA mRNA
CTD PMID:25905778, PMID:29127188 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression
multiple interactions
EXP Streptozocin results in increased expression of CISD1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CISD1 protein]
CTD PMID:19634143 NCBI chr20:18,493,538...18,506,923
Ensembl chr20:18,493,538...18,506,912
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression
decreases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of CITED2 mRNA
Streptozocin results in decreased expression of CITED2 mRNA
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of CITED2 mRNA]
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CITED2 mRNA]
CTD PMID:16684804, PMID:27629361 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Ckmt2 creatine kinase, mitochondrial 2 multiple interactions
decreases expression
EXP vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of CKMT2 mRNA] CTD PMID:16684804 NCBI chr 2:21,422,680...21,452,797
Ensembl chr 2:21,422,818...21,437,193
JBrowse link
G Cldn1 claudin 1 decreases expression EXP Streptozocin results in decreased expression of CLDN1 mRNA CTD PMID:25905778 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cldn11 claudin 11 decreases expression
multiple interactions
ISO Streptozocin results in decreased expression of CLDN11 protein
rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CLDN11 protein]
CTD PMID:31682803 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Cldn2 claudin 2 decreases expression EXP Streptozocin results in decreased expression of CLDN2 mRNA CTD PMID:25905778 NCBI chr  X:111,122,552...111,133,188
Ensembl chr  X:111,122,552...111,137,769
JBrowse link
G Clec4f C-type lectin domain family 4, member F multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CLEC4F mRNA CTD PMID:25905778 NCBI chr 4:115,322,300...115,332,021
Ensembl chr 4:115,322,291...115,332,052
JBrowse link
G Clic4 chloride intracellular channel 4 affects expression ISO Streptozocin affects the expression of CLIC4 mRNA CTD PMID:18583417 NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression ISO Streptozocin affects the expression of CLPP mRNA CTD PMID:18583417 NCBI chr 9:10,048,715...10,056,068
Ensembl chr 9:10,048,886...10,054,359
JBrowse link
G Clu clusterin increases expression
multiple interactions
EXP Streptozocin results in increased expression of CLU protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CLU protein]
CTD PMID:19634143 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP [Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA] CTD PMID:31468622 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA] CTD PMID:28700904, PMID:29988851 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression
multiple interactions
increases expression
ISO
EXP
Streptozocin results in decreased expression of COL4A1 mRNA
[fatostatin co-treated with Streptozocin] results in increased expression of COL4A1 mRNA
Streptozocin results in increased expression of COL4A1 mRNA
benazepril inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; MFN2 protein mutant form inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]
CTD PMID:11798618, PMID:15496156, PMID:17582205, PMID:27997345, PMID:29420703 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col4a3 collagen type IV alpha 3 chain multiple interactions
increases expression
EXP Zinc inhibits the reaction [Streptozocin results in increased expression of COL4A3 mRNA] CTD PMID:31009641 NCBI chr 9:88,357,528...88,484,735
Ensembl chr 9:88,357,556...88,485,830
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression
multiple interactions
EXP Streptozocin results in increased expression of COL6A1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A1 protein]
CTD PMID:19634143 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Col6a2 collagen type VI alpha 2 chain increases expression
multiple interactions
EXP Streptozocin results in increased expression of COL6A2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A2 protein]
CTD PMID:19634143 NCBI chr20:12,773,472...12,801,179
Ensembl chr20:12,773,427...12,801,180
JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression
multiple interactions
EXP Streptozocin results in increased expression of COL6A3 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A3 protein]
CTD PMID:19634143 NCBI chr 9:97,926,784...98,004,643
Ensembl chr 9:97,926,787...98,004,546
JBrowse link
G Cotl1 coactosin-like F-actin binding protein 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of COTL1 mRNA CTD PMID:25905778 NCBI chr19:52,465,074...52,499,433
Ensembl chr19:52,465,087...52,499,433
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 affects expression ISO Streptozocin affects the expression of COX17 mRNA CTD PMID:18583417 NCBI chr11:64,962,663...64,968,437
Ensembl chr11:64,962,666...64,968,437
JBrowse link
G Cp ceruloplasmin multiple interactions
decreases expression
EXP caryophyllene inhibits the reaction [Streptozocin results in decreased expression of CP protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CP protein] CTD PMID:26748309 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of CPT1A mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA]
[resveratrol co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA]
CTD PMID:16684804, PMID:25905778, PMID:29988851 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression
multiple interactions
EXP Streptozocin results in increased expression of CPT2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CPT2 protein]
CTD PMID:21136691 NCBI chr 5:127,505,646...127,523,016
Ensembl chr 5:127,505,614...127,523,089
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
decreases phosphorylation
EXP
ISO
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CREB1 mRNA; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; MIR10A mRNA affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]
CTD PMID:20665664, PMID:23562514, PMID:27292126 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crebbp CREB binding protein decreases expression EXP Streptozocin results in decreased expression of CREBBP mRNA CTD PMID:25905778 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CROT mRNA
[resveratrol co-treated with Streptozocin] results in decreased expression of CROT mRNA
CTD PMID:25905778 NCBI chr 4:22,079,837...22,116,265
Ensembl chr 4:22,081,604...22,116,265
JBrowse link
G Cry1 cryptochrome circadian regulator 1 increases expression EXP Streptozocin results in increased expression of CRY1 mRNA CTD PMID:25905778 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Cryz crystallin zeta decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CRYZ protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of CRYZ protein]
CTD PMID:19634143 NCBI chr 2:260,884,315...260,911,827
Ensembl chr 2:260,884,337...260,911,792
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CSF1R mRNA CTD PMID:25905778 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression
multiple interactions
EXP Streptozocin results in increased expression of CSRP3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CSRP3 mRNA]
CTD PMID:16684804 NCBI chr 1:104,147,205...104,166,389
Ensembl chr 1:104,147,206...104,166,367
JBrowse link
G Cst3 cystatin C multiple interactions EXP [Streptozocin co-treated with Fructose] results in increased expression of CST3 protein; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CST3 protein] CTD PMID:30551545 NCBI chr 3:143,219,671...143,223,544
Ensembl chr 3:143,219,686...143,223,615
JBrowse link
G Cth cystathionine gamma-lyase multiple interactions ISO [Streptozocin co-treated with Dietary Fats] affects the expression of CTH mRNA CTD PMID:29127188 NCBI chr 2:264,266,959...264,293,040
Ensembl chr 2:264,266,984...264,293,046
JBrowse link
G Ctsk cathepsin K increases expression EXP Streptozocin results in increased expression of CTSK mRNA; Streptozocin results in increased expression of CTSK protein CTD PMID:25617479 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Ctss cathepsin S increases expression
multiple interactions
EXP Streptozocin results in increased expression of CTSS mRNA
[resveratrol co-treated with Streptozocin] results in increased expression of CTSS mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CTSS mRNA]
CTD PMID:16684804, PMID:25905778 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
decreases expression
ISO [Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA]
Streptozocin results in decreased expression of CXCL12 mRNA; Streptozocin results in decreased expression of CXCL12 protein
CTD PMID:18227068 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions EXP [Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCR4 protein CTD PMID:30421503 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
increases expression
EXP [resveratrol co-treated with Streptozocin] results in increased expression of CYBA mRNA; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA] CTD PMID:12967931, PMID:16139267, PMID:25905778 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of CYBB protein; Streptozocin results in increased expression of NOX2 mRNA
[fatostatin co-treated with Streptozocin] results in increased expression of NOX2 mRNA; Telmisartan inhibits the reaction [Streptozocin results in increased expression of CYBB protein]
CTD PMID:19957251, PMID:21381899, PMID:29420703 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyc1 cytochrome c-1 increases expression
multiple interactions
EXP Streptozocin results in increased expression of CYC1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of CYC1 protein]
CTD PMID:19634143 NCBI chr 7:117,409,576...117,411,953
Ensembl chr 7:117,409,576...117,411,953
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
EXP Streptozocin affects the localization of CYCS protein
arjunolic acid inhibits the reaction [Streptozocin affects the localization of CYCS protein]; Thioctic Acid inhibits the reaction [Streptozocin affects the localization of CYCS protein]
CTD PMID:19682444, PMID:19951573 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 increases expression EXP Streptozocin results in increased expression of CYP11B2 mRNA; Streptozocin results in increased expression of CYP11B2 protein CTD PMID:16043663 NCBI chr 7:116,155,928...116,161,781
Ensembl chr 7:116,156,219...116,255,167
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO
EXP
Metformin promotes the reaction [Streptozocin results in increased expression of CYP1A1 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP1A1 mRNA]
[resveratrol co-treated with Streptozocin] results in increased expression of CYP1A1 mRNA
CTD PMID:22342832, PMID:25905778, PMID:29382564 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression
multiple interactions
increases expression
ISO
EXP
Streptozocin results in decreased expression of CYP1A2 protein
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP1A2 mRNA
Streptozocin results in decreased expression of CYP1A2 mRNA
[resveratrol co-treated with Streptozocin] results in decreased expression of CYP1A2 mRNA; [Streptozocin results in increased expression of CYP1A2 protein] which results in increased metabolism of Diazinon
CTD PMID:12700423, PMID:17442507, PMID:25905778, PMID:29127188 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CYP26A1 mRNA CTD PMID:25905778 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CYP26B1 mRNA CTD PMID:25905778 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP27A1 mRNA CTD PMID:29382564 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 decreases expression EXP Streptozocin results in decreased expression of CYP2A1 mRNA CTD PMID:25905778 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO
EXP
Berberine inhibits the reaction [Streptozocin results in increased expression of CYP2B10 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP2B10 mRNA]
[resveratrol co-treated with Streptozocin] results in increased expression of CYP2B1 mRNA
Streptozocin results in increased expression of CYP2B1 mRNA
CTD PMID:22342832, PMID:25905778, PMID:29382564 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2B13 mRNA CTD PMID:29127188 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
increases expression
ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2B9 mRNA; Berberine promotes the reaction [Streptozocin results in increased expression of CYP2B9 mRNA]; Metformin promotes the reaction [Streptozocin results in increased expression of CYP2B9 mRNA] CTD PMID:22342832, PMID:29127188 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 protein CTD PMID:24815820 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
multiple interactions
increases expression
ISO
EXP
Streptozocin results in decreased expression of CYP2E1 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased activity of CYP2E1 protein
Streptozocin results in increased expression of CYP2E1 mRNA; Streptozocin results in increased expression of CYP2E1 protein
CTD PMID:11752103, PMID:12700423, PMID:14693714, PMID:24815820, PMID:25905778 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression EXP Streptozocin results in increased expression of CYP2J4 mRNA CTD PMID:25905778 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CYP4A1 mRNA
[Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 protein; [Resveratrol co-treated with Streptozocin] results in decreased expression of CYP4A1 mRNA
CTD PMID:24815820, PMID:25905778 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of CYP4A2 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A2 mRNA; Trientine promotes the reaction [Streptozocin results in decreased expression of CYP4A2 protein]
CTD PMID:19634143, PMID:24815820 NCBI chr 5:134,196,910...134,207,888
Ensembl chr 5:134,196,912...134,207,863
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP4F14 mRNA CTD PMID:29127188 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of CYP7A1 mRNA
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein]
CTD PMID:10393316, PMID:29382564, PMID:31100278 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7B1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP7B1 mRNA CTD PMID:29127188, PMID:29382564 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions
increases expression
EXP
ISO
[resveratrol co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CYP8B1 mRNA]; Streptozocin inhibits the reaction [resveratrol results in increased expression of CYP8B1 mRNA]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA
Streptozocin results in increased expression of CYP8B1 mRNA; Streptozocin results in increased expression of CYP8B1 protein
CTD PMID:10393316, PMID:25905778, PMID:29382564 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 multiple interactions
increases expression
ISO montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 mRNA]; montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 protein]
Streptozocin results in increased expression of CYSLTR1 mRNA; Streptozocin results in increased expression of CYSLTR1 protein
CTD PMID:27702591 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Cyyr1 cysteine and tyrosine rich 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of CYYR1 mRNA CTD PMID:25905778 NCBI chr11:24,967,936...25,078,740
Ensembl chr11:24,967,937...25,078,740
JBrowse link
G Dao D-amino-acid oxidase increases expression
multiple interactions
EXP Streptozocin results in increased expression of DAO protein
Trientine inhibits the reaction [Streptozocin results in increased expression of DAO protein]
CTD PMID:19634143 NCBI chr12:48,353,691...48,373,647
Ensembl chr12:48,354,196...48,365,784
JBrowse link
G Dapk1 death associated protein kinase 1 decreases expression EXP Streptozocin results in decreased expression of DAPK1 mRNA CTD PMID:25905778 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Dbn1 drebrin 1 decreases expression EXP Streptozocin results in decreased expression of DBN1 protein CTD PMID:23333261 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 affects expression ISO Streptozocin affects the expression of DBT mRNA CTD PMID:18583417 NCBI chr 2:219,563,783...219,592,651
Ensembl chr 2:219,563,783...219,592,650
JBrowse link
G Dcc DCC netrin 1 receptor multiple interactions
increases expression
ISO NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC protein]
Streptozocin results in increased expression of DCC mRNA; Streptozocin results in increased expression of DCC protein
CTD PMID:29059224 NCBI chr18:66,518,213...67,629,801
Ensembl chr18:66,523,120...67,224,566
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO
EXP
Streptozocin results in increased expression of DDIT3; Streptozocin results in increased expression of DDIT3 mRNA; Streptozocin results in increased expression of DDIT3 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]
[Streptozocin co-treated with bisphenol A] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 protein; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Streptozocin promotes the reaction [bisphenol A results in increased expression of DDIT3 mRNA]; sulforafan inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]
CTD PMID:23499715, PMID:24967692, PMID:29935216, PMID:30980806 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of DDIT4 mRNA CTD PMID:25905778 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression
multiple interactions
EXP Streptozocin results in increased expression of DECR1 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of DECR1 mRNA]
CTD PMID:16684804 NCBI chr 5:29,573,893...29,601,731
Ensembl chr 5:29,573,898...29,601,748
JBrowse link
G Derl1 derlin 1 multiple interactions
increases expression
EXP 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DERL1 protein] CTD PMID:30980806 NCBI chr 7:97,737,176...97,759,852
Ensembl chr 7:97,737,178...97,759,852
JBrowse link
G Des desmin multiple interactions
increases expression
EXP Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of DES protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of DES protein] CTD PMID:12197670, PMID:17624267 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dgkh diacylglycerol kinase, eta multiple interactions EXP [Streptozocin co-treated with Dietary Fats] results in decreased expression of DGKH mRNA CTD PMID:20665664 NCBI chr15:60,791,574...60,967,236
Ensembl chr15:60,803,098...60,959,769
JBrowse link
G Dhrs7 dehydrogenase/reductase 7 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of DHRS7 mRNA CTD PMID:25905778 NCBI chr 6:95,522,577...95,541,393
Ensembl chr 6:95,522,577...95,541,393
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of DHRS9 mRNA CTD PMID:29127188 NCBI chr 3:55,623,671...55,645,883
Ensembl chr 3:55,623,634...55,648,325
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions ISO [Streptozocin co-treated with NQO1 protein mutant form] results in increased secretion of DIABLO protein CTD PMID:23458895 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Dio1 iodothyronine deiodinase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of DIO1 mRNA CTD PMID:25905778 NCBI chr 5:126,894,837...126,911,532
Ensembl chr 5:126,895,286...126,911,520
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase multiple interactions
increases expression
EXP Trientine inhibits the reaction [Streptozocin results in increased expression of DLAT protein] CTD PMID:21136691 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832
JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression
multiple interactions
EXP Streptozocin results in increased expression of DLD protein
Trientine inhibits the reaction [Streptozocin results in increased expression of DLD protein]
CTD PMID:21136691 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions
decreases expression
EXP Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein] CTD PMID:24333387 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
JBrowse link
G Dlgap2 DLG associated protein 2 multiple interactions
decreases expression
EXP Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] CTD PMID:24333387 NCBI chr16:79,872,238...80,596,977
Ensembl chr16:79,872,323...79,973,877
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions
increases expression
EXP Trientine inhibits the reaction [Streptozocin results in increased expression of DLST protein] CTD PMID:19634143, PMID:21136691 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of DMBT1 mRNA CTD PMID:25905778 NCBI chr 1:201,620,642...201,689,905
NCBI chr 1:203,149,414...203,228,705
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
increases expression
EXP ferulic acid inhibits the reaction [Streptozocin results in increased expression of DNM1L protein] CTD PMID:31029786 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases expression
ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 protein; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA] CTD PMID:28422052, PMID:29127188 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A protein CTD PMID:29127188 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B protein CTD PMID:29127188 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases response to substance
increases expression
decreases expression
decreases activity
EXP DPP4 results in increased susceptibility to Streptozocin
Streptozocin results in increased expression of DPP4 mRNA
Streptozocin results in decreased expression of DPP4 protein
Streptozocin results in decreased activity of DPP4 protein
CTD PMID:16045816, PMID:18931022 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 increases expression EXP Streptozocin results in increased expression of ECHS1 protein CTD PMID:21136691 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression EXP Streptozocin results in increased expression of EDEM1 mRNA CTD PMID:25905778 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression
EXP
ISO
Bezafibrate inhibits the reaction [Streptozocin results in increased expression of EDN1 mRNA]
diphenyleneiodonium inhibits the reaction [Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]
CTD PMID:12458661, PMID:12967931, PMID:20691780 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Efnb2 ephrin B2 affects expression ISO Streptozocin affects the expression of EFNB2 mRNA CTD PMID:26073000 NCBI chr16:86,631,151...86,672,050
Ensembl chr16:86,631,064...86,675,049
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression EXP Streptozocin results in increased expression of EHHADH mRNA CTD PMID:25905778 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
increases expression
EXP vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of EIF4EBP1 mRNA] CTD PMID:16684804 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Elk1 ETS transcription factor ELK1 increases phosphorylation EXP Streptozocin results in increased phosphorylation of ELK1 protein CTD PMID:12642375 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Elovl7 ELOVL fatty acid elongase 7 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of ELOVL7 mRNA CTD PMID:29127188 NCBI chr 2:40,373,211...40,386,643
Ensembl chr 2:40,373,211...40,386,669
JBrowse link
G Eno1 enolase 1 increases expression EXP Streptozocin results in increased expression of ENO1 protein CTD PMID:24924950 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Eno1-ps1 enolase 1, (alpha), pseudogene 1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of ENO1-PS1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ENO1-PS1 protein]
CTD PMID:19634143 NCBI chr 3:59,408,531...59,410,209 JBrowse link
G Enpep glutamyl aminopeptidase multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of ENPEP mRNA CTD PMID:25905778 NCBI chr 2:233,667,253...233,743,866
Ensembl chr 2:233,667,254...233,743,866
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of ENPP2 mRNA CTD PMID:25905778 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Ep300 E1A binding protein p300 increases expression
multiple interactions
EXP Streptozocin results in increased expression of EP300 mRNA
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]
CTD PMID:22228707 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of EPCAM mRNA CTD PMID:25905778 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression
multiple interactions
EXP Streptozocin results in increased expression of EPHX1 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein]
CTD PMID:19634143 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 increases expression
decreases response to substance
multiple interactions
EXP
ISO
Streptozocin results in increased expression of EPHX2 protein
EPHX2 gene mutant form results in decreased susceptibility to Streptozocin
EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased activity of RELA protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]
CTD PMID:21832210, PMID:23611540 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Epo erythropoietin multiple interactions
increases expression
decreases expression
EXP Enalapril inhibits the reaction [Streptozocin results in increased expression of EPO mRNA]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPO protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPO mRNA] CTD PMID:19958114, PMID:20821229 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor multiple interactions
increases expression
decreases expression
EXP Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA]
Streptozocin results in increased expression of EPOR mRNA; Streptozocin results in increased expression of EPOR protein
CTD PMID:19958114, PMID:20821229 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit increases expression
multiple interactions
EXP Streptozocin results in increased expression of ERCC1 mRNA; Streptozocin results in increased expression of ERCC1 protein
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]
CTD PMID:22228707 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit multiple interactions
increases expression
EXP 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]
Streptozocin results in increased expression of ERCC4 mRNA; Streptozocin results in increased expression of ERCC4 protein
CTD PMID:22228707 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression
EXP 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form] CTD PMID:20399799 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
decreases expression
ISO
EXP
bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]
Streptozocin results in increased expression of ESR1
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of ESR1 protein
CTD PMID:24781736, PMID:30421503, PMID:32469605 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
decreases expression
ISO bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA] CTD PMID:24781736 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Etfa electron transfer flavoprotein subunit alpha decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of ETFA protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFA protein]
CTD PMID:19634143 NCBI chr 8:60,028,786...60,086,352
Ensembl chr 8:60,028,789...60,086,403
JBrowse link
G Etfb electron transfer flavoprotein subunit beta decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of ETFB protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFB protein]
CTD PMID:19634143 NCBI chr 1:98,472,776...98,486,940
Ensembl chr 1:98,472,745...98,486,976
JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase affects expression ISO Streptozocin affects the expression of ETFDH mRNA CTD PMID:18583417 NCBI chr 2:178,367,547...178,389,641
Ensembl chr 2:178,367,549...178,389,608
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions
decreases expression
ISO SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ETS1 mRNA] CTD PMID:27629361 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 protein CTD PMID:29127188 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of FABP4 mRNA CTD PMID:29127188 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fabp7 fatty acid binding protein 7 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of FABP7 mRNA CTD PMID:29127188 NCBI chr20:40,769,624...40,773,156
Ensembl chr20:40,769,586...40,773,349
JBrowse link
G Fadd Fas associated via death domain multiple interactions
increases expression
EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FADD protein] CTD PMID:28856781 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fads1 fatty acid desaturase 1 decreases expression EXP Streptozocin results in decreased expression of FADS1 mRNA CTD PMID:25246140 NCBI chr 1:226,234,034...226,249,118
Ensembl chr 1:226,234,074...226,249,138
JBrowse link
G Fars2 phenylalanyl-tRNA synthetase 2, mitochondrial affects expression ISO Streptozocin affects the expression of FARS2 mRNA CTD PMID:18583417 NCBI chr17:29,006,981...29,438,906
Ensembl chr17:29,006,988...29,438,668
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FAS protein] CTD PMID:28856781 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions
increases expression
EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FASLG protein]; rosiglitazone inhibits the reaction [Streptozocin results in increased expression of FASLG mRNA]
Streptozocin results in increased expression of FASLG mRNA; Streptozocin results in increased expression of FASLG protein
CTD PMID:21791967, PMID:28856781 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression
decreases expression
EXP
ISO
Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN protein]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN protein]
[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]
Streptozocin results in increased expression of FASN mRNA; Streptozocin results in increased expression of FASN protein
CTD PMID:20219977, PMID:23647015, PMID:27769711, PMID:29988851 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fbp1 fructose-bisphosphatase 1 increases activity
multiple interactions
EXP Streptozocin results in increased activity of FBP1 protein
citronellol inhibits the reaction [Streptozocin results in increased activity of FBP1 protein]
CTD PMID:26944432 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fbp2 fructose-bisphosphatase 2 multiple interactions ISO [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein CTD PMID:25446853 NCBI chr17:372,554...389,918
Ensembl chr17:372,551...389,967
JBrowse link
G Fbxo32 F-box protein 32 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of FBXO32 protein
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of FBXO32 protein]
CTD PMID:30635400, PMID:30980806 NCBI chr 7:98,065,664...98,098,071
Ensembl chr 7:98,063,735...98,098,268
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of FCER1G mRNA CTD PMID:25905778 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G Fcgr2a Fc fragment of IgG receptor IIa increases expression
multiple interactions
EXP Streptozocin results in increased expression of FCGR3 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of FCGR3 mRNA]
CTD PMID:16684804 NCBI chr13:91,146,878...91,163,691
Ensembl chr13:91,168,973...91,198,036
Ensembl chr13:91,168,973...91,198,036
JBrowse link
G Fcna ficolin A multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of FCNA mRNA CTD PMID:25905778 NCBI chr 3:2,850,006...2,853,230
Ensembl chr 3:2,849,984...2,853,272
JBrowse link
G Fgf17 fibroblast growth factor 17 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA] CTD PMID:32303808 NCBI chr15:52,326,758...52,337,360
Ensembl chr15:52,326,778...52,332,097
JBrowse link
G Fgf19 fibroblast growth factor 19 multiple interactions ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 protein CTD PMID:29382564 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G Fgf21 fibroblast growth factor 21 multiple interactions
affects response to substance
ISO [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FGF21 mRNA; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1]; FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Glucagon analog promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein]
FGF21 protein affects the susceptibility to Streptozocin
CTD PMID:23499715, PMID:29127188, PMID:29988851 NCBI chr 1:101,595,579...101,596,822
Ensembl chr 1:101,595,579...101,596,822
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 multiple interactions
decreases expression
EXP rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of FGFR1] CTD PMID:24136780 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fh fumarate hydratase affects expression ISO Streptozocin affects the expression of FH1 mRNA CTD PMID:18583417 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
G Fitm2 fat storage-inducing transmembrane protein 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of FITM2 mRNA CTD PMID:25905778 NCBI chr 3:159,856,994...159,863,506
Ensembl chr 3:159,856,994...159,863,506
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions ISO Streptozocin promotes the reaction [bisphenol A results in decreased expression of FKBP1B mRNA]; Streptozocin promotes the reaction [octylphenol results in decreased expression of FKBP1B mRNA] CTD PMID:29935216 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions
increases expression
EXP
ISO
Simvastatin inhibits the reaction [Streptozocin results in increased expression of FLT1 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein]; Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein CTD PMID:20821229, PMID:26073000 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases expression EXP Streptozocin results in increased expression of FMO2 mRNA CTD PMID:25905778 NCBI chr13:80,752,526...80,775,264
Ensembl chr13:80,755,058...80,775,264
JBrowse link
G Fmo4 flavin containing dimethylaniline monoxygenase 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of FMO4 mRNA CTD PMID:25905778 NCBI chr13:80,685,385...80,703,575
Ensembl chr13:80,685,325...80,703,615
JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions
EXP
ISO
Streptozocin results in increased expression of FN1; Streptozocin results in increased expression of FN1 mRNA; Streptozocin results in increased expression of FN1 protein
[fatostatin co-treated with Streptozocin] results in increased expression of FN1 mRNA; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; Aspirin inhibits the reaction [Streptozocin results in increased expression of FN1]; benazepril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Carvedilol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of FN1 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]
CTD PMID:11798618, PMID:12140129, PMID:14586741, PMID:16973718, PMID:19895808, PMID:21300041, PMID:21450970, PMID:21998146, PMID:22228707, PMID:22733486, PMID:23376009, PMID:23611540, PMID:24413998, PMID:24877639, PMID:25057273, PMID:25240712, PMID:25301743, PMID:26341651, PMID:27292126, PMID:29420703, PMID:31009641 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Foxa2 forkhead box A2 multiple interactions EXP copper bis(3,5-diisopropylsalicylate) inhibits the reaction [Streptozocin results in decreased expression of FOXA2] CTD PMID:23795780 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Foxo1 forkhead box O1 multiple interactions
decreases expression
increases acetylation
ISO
EXP
[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein; resveratrol inhibits the reaction [Streptozocin results in increased acetylation of FOXO1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein]
Streptozocin results in decreased expression of FOXO1 mRNA
[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of FOXO1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein
CTD PMID:22733486, PMID:24889822, PMID:26522834, PMID:27270450 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Foxo3 forkhead box O3 decreases expression
multiple interactions
increases expression
EXP
ISO
Streptozocin results in decreased expression of FOXO3 protein
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased phosphorylation of FOXO3 protein; [Streptozocin co-treated with Resveratrol] results in increased phosphorylation of FOXO3 protein; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FOXO3 protein]
Streptozocin results in increased expression of FOXO3 protein; Streptozocin results in increased expression of FOXO3 protein modified form
CTD PMID:17082237, PMID:18703049, PMID:23792339, PMID:31062909 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of FSHB protein
Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of FSHB protein]; vitexin inhibits the reaction [Streptozocin results in decreased expression of FSHB protein]
CTD PMID:19931367, PMID:30365938 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA]; Omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA] CTD PMID:32410268 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of FXYD2 mRNA CTD PMID:25905778 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
decreases expression
increases expression
increases activity
decreases activity
EXP
ISO
4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in increased activity of G6PC protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of G6PC mRNA]; citronellol inhibits the reaction [Streptozocin results in increased activity of G6PC protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of G6PC protein]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of G6PC protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of G6PC mRNA]; plumbagin inhibits the reaction [Streptozocin results in increased activity of G6PC protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of G6PC protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of G6PC protein]
Streptozocin results in decreased expression of G6PC mRNA
Streptozocin results in increased expression of G6PC mRNA; Streptozocin results in increased expression of G6PC protein
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC mRNA; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC mRNA]
CTD PMID:12446591, PMID:19634143, PMID:22960630, PMID:25446853, PMID:25641191, PMID:25905778, PMID:26522834, PMID:26616445, PMID:26944432, PMID:27038876, PMID:27769711 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions
decreases activity
EXP 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein; [Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; citronellol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein] CTD PMID:19059388, PMID:19133311, PMID:19682444, PMID:24923654, PMID:25641191, PMID:26944432, PMID:28330423, PMID:28757134 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA] CTD PMID:32303808 NCBI chr 5:48,374,048...48,411,170
Ensembl chr 5:48,374,096...48,411,170
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
decreases expression
EXP Curcumin inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA] CTD PMID:23267840 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions EXP
ISO
[resveratrol co-treated with Streptozocin] results in increased expression of GADD45B mRNA
[Streptozocin co-treated with Dietary Fats] results in increased expression of GADD45B mRNA
CTD PMID:25905778, PMID:29127188 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Galt galactose-1-phosphate uridylyltransferase decreases expression EXP Streptozocin results in decreased expression of GALT mRNA CTD PMID:25905778 NCBI chr 5:58,144,679...58,147,946
Ensembl chr 5:58,144,705...58,147,929
JBrowse link
G Gas6 growth arrest specific 6 increases expression EXP Streptozocin results in increased expression of GAS6 protein CTD PMID:12644472 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gatm glycine amidinotransferase multiple interactions
decreases expression
EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of GATM protein] CTD PMID:19634143 NCBI chr 3:114,711,570...114,728,155
Ensembl chr 3:114,711,562...114,728,410
JBrowse link
G Gcg glucagon multiple interactions
decreases expression
EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of GCG mRNA]; Sitagliptin Phosphate inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA] CTD PMID:18998217, PMID:23466488, PMID:27270450 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Gck glucokinase multiple interactions
decreases expression
ISO
EXP
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK mRNA
Streptozocin results in decreased expression of GCK mRNA
Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GCK mRNA]
CTD PMID:25446853, PMID:26522834, PMID:27038876, PMID:27769711, PMID:29127188 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein]; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein] CTD PMID:21439372 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) increases expression EXP Streptozocin results in increased expression of GCNT2 mRNA CTD PMID:25905778 NCBI chr17:21,634,546...21,677,477
Ensembl chr17:21,634,551...21,739,408
JBrowse link
G Gda guanine deaminase increases expression EXP Streptozocin results in increased expression of GDA mRNA CTD PMID:25905778 NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
decreases expression
increases expression
EXP
ISO
Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein]
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]
Streptozocin results in increased expression of GFAP mRNA; Streptozocin results in increased expression of GFAP protein
CTD PMID:24333387, PMID:28499986 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gfm1 G elongation factor, mitochondrial 1 affects expression ISO Streptozocin affects the expression of GFM1 mRNA CTD PMID:18583417 NCBI chr 2:164,601,575...164,646,478
Ensembl chr 2:164,601,586...164,646,439
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of GGT1 protein
[resveratrol co-treated with Streptozocin] results in increased expression of GGT1 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of GGT1 protein]
CTD PMID:19634143, PMID:25905778 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Ghr growth hormone receptor multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of GHR mRNA CTD PMID:25905778 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions EXP GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA] CTD PMID:20219977 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Gk glycerol kinase decreases expression EXP Streptozocin results in decreased expression of GK mRNA CTD PMID:25905778 NCBI chr  X:54,227,291...54,303,897
Ensembl chr  X:54,227,397...54,303,864
JBrowse link
G Glb1 galactosidase, beta 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of GLB1 protein
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]
CTD PMID:29673160 NCBI chr 8:122,439,328...122,511,939
Ensembl chr 8:122,439,328...122,511,939
JBrowse link
G Glo1 glyoxalase 1 multiple interactions EXP [Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein]; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein] CTD PMID:21439372 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions EXP [Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA] CTD PMID:31468622 NCBI chr20:9,586,075...9,626,228
Ensembl chr20:9,586,075...9,626,228
JBrowse link
G Glul glutamate-ammonia ligase multiple interactions
decreases expression
EXP [resveratrol co-treated with Streptozocin] results in increased expression of GLUL mRNA; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL protein]
Streptozocin results in decreased expression of GLUL mRNA; Streptozocin results in decreased expression of GLUL protein
CTD PMID:25905778, PMID:26677078 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gna11 G protein subunit alpha 11 multiple interactions
increases expression
EXP acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein] CTD PMID:20691780 NCBI chr 7:11,033,400...11,047,284
Ensembl chr 7:11,033,317...11,047,437
JBrowse link
G Gnai2 G protein subunit alpha i2 multiple interactions
decreases expression
EXP Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein] CTD PMID:18441196 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gnai3 G protein subunit alpha i3 multiple interactions
decreases expression
EXP Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] CTD PMID:18441196 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Gnaq G protein subunit alpha q multiple interactions
increases expression
EXP acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein] CTD PMID:20691780 NCBI chr 1:233,382,778...233,622,584
Ensembl chr 1:233,382,708...233,622,786
JBrowse link
G Gnmt glycine N-methyltransferase multiple interactions
increases expression
increases activity
EXP Folic Acid inhibits the reaction [Streptozocin results in increased activity of GNMT protein]
Streptozocin results in increased expression of GNMT mRNA; Streptozocin results in increased expression of GNMT protein
CTD PMID:16835399 NCBI chr 9:16,565,274...16,568,626
Ensembl chr 9:16,565,225...16,568,627
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions
increases secretion
EXP [Resveratrol co-treated with Streptozocin] results in decreased expression of GOT1 mRNA; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GOT1 protein] CTD PMID:25905778, PMID:30657622 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression
multiple interactions
EXP Streptozocin results in increased expression of GOT2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GOT2 protein]
CTD PMID:19634143 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpc1 glypican 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of GPC1 mRNA CTD PMID:29127188 NCBI chr 9:99,998,275...100,026,818
Ensembl chr 9:99,998,275...100,026,818
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of GPD1 mRNA CTD PMID:25905778 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gprc6a G protein-coupled receptor, class C, group 6, member A multiple interactions EXP [Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA] CTD PMID:27488359 NCBI chr20:32,607,653...32,628,953
Ensembl chr20:32,607,653...32,628,953
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases secretion
increases activity
increases expression
EXP
ISO
[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]]; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GPT protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of GPT protein]; mangiferin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; naringenin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of GPT protein]; sodium tungstate(VI) inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [Omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]
CTD PMID:11357483, PMID:24854284, PMID:24877639, PMID:26071184, PMID:27350165, PMID:29223569, PMID:29614383, PMID:30144451, PMID:30657622, PMID:30927557, PMID:31100278, PMID:31743741, PMID:32410268 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression
increases expression
decreases activity
ISO
EXP
Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]
Curcumin inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of GPX1 protein]
CTD PMID:18789669, PMID:19634143, PMID:23267840, PMID:24740756 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of GPX2 mRNA CTD PMID:25905778 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression
multiple interactions
EXP Streptozocin results in increased expression of GPX3 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of GPX3 protein]
CTD PMID:19634143 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression EXP Streptozocin results in increased expression of GREM1 mRNA CTD PMID:10744662 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 multiple interactions
increases expression
EXP Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein] CTD PMID:23267840 NCBI chr 8:1,548,145...2,045,874
Ensembl chr 8:1,548,146...2,045,817
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
increases expression
EXP Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]
Streptozocin results in increased expression of GRIN1 mRNA; Streptozocin results in increased expression of GRIN1 protein
CTD PMID:23267840 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grm5 glutamate metabotropic receptor 5 increases expression EXP Streptozocin results in increased expression of GRM5 protein CTD PMID:19840219 NCBI chr 1:151,207,846...151,785,038
Ensembl chr 1:151,439,409...151,783,392
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
increases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased phosphorylation of GSK3B protein
Streptozocin results in increased expression of GSK3B mRNA
[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of GSK3B mRNA]
CTD PMID:25541178, PMID:27038876, PMID:28422052, PMID:31877369 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions
affects activity
increases activity
decreases activity
EXP [Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Streptozocin; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein; [Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of GSR protein] CTD PMID:11424224, PMID:15720826, PMID:17145126, PMID:19682444, PMID:19840221, PMID:20053369, PMID:20307516, PMID:20620209, PMID:21439372, PMID:22476978, PMID:22940631, PMID:23122718, PMID:24752916, PMID:24877639, PMID:26341651, PMID:26748309, PMID:30817903, PMID:31009641 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP [Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein] CTD PMID:26474837 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
decreases expression
multiple interactions
EXP Streptozocin results in increased expression of GSTA2 protein; Streptozocin results in increased expression of GSTA3 mRNA
Streptozocin results in decreased expression of GSTA3 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of GSTA3 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of GSTA2 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTA3 mRNA]
CTD PMID:16684804, PMID:19634143 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta4 glutathione S-transferase alpha 4 increases expression EXP Streptozocin results in increased expression of GSTA4 protein CTD PMID:14693714 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 multiple interactions
increases expression
EXP [resveratrol co-treated with Streptozocin] results in increased expression of GSTA5 mRNA
Streptozocin results in increased expression of GSTA5 mRNA
CTD PMID:25905778 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression
multiple interactions
EXP Streptozocin results in increased expression of GSTM2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM2 mRNA]
CTD PMID:16684804 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm3l glutathione S-transferase mu 3-like increases expression
multiple interactions
EXP Streptozocin results in increased expression of GSTM5 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM5 mRNA]
CTD PMID:16684804 NCBI chr 2:210,761,729...210,766,501
Ensembl chr 2:210,761,729...210,766,501
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions EXP [Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA] CTD PMID:21439372 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression EXP Streptozocin results in decreased expression of GSTP1 mRNA CTD PMID:25905778 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gucy1b2 guanylate cyclase 1 soluble subunit beta 2 decreases expression EXP Streptozocin results in decreased expression of GUCY1B2 mRNA CTD PMID:25905778 NCBI chr15:45,479,662...45,550,285
Ensembl chr15:45,479,658...45,550,285
JBrowse link
G Gys1 glycogen synthase 1 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of GYS1 mRNA
Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GYS1 mRNA]
CTD PMID:27038876 NCBI chr 1:101,427,195...101,447,092
Ensembl chr 1:101,427,195...101,447,092
JBrowse link
G Gys2 glycogen synthase 2 multiple interactions EXP [Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein] CTD PMID:19059388 NCBI chr 4:176,638,632...176,679,805
Ensembl chr 4:176,638,629...176,679,815
JBrowse link
G Hamp hepcidin antimicrobial peptide multiple interactions EXP [Streptozocin co-treated with iron pentacarbonyl] results in increased expression of HAMP mRNA CTD PMID:22170771 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Hao2 hydroxyacid oxidase 2 multiple interactions
decreases expression
EXP [resveratrol co-treated with Streptozocin] results in decreased expression of HAO2 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of HAO2 protein]
Streptozocin results in decreased expression of HAO2 mRNA; Streptozocin results in decreased expression of HAO2 protein
CTD PMID:19634143, PMID:25905778 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of HAVCR1 mRNA
2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; [Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; Metformin promotes the reaction [2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]
CTD PMID:19516248, PMID:30551545 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions
increases glycation
EXP [Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein]
Streptozocin results in increased glycation of HBA1 protein
CTD PMID:19647726, PMID:21139377 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hbb hemoglobin subunit beta decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of HBB-B1 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HBB-B1 protein]
CTD PMID:19634143 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of HCK mRNA CTD PMID:25905778 NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033
JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of HDAC3 protein; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] CTD PMID:27292126 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Streptozocin results in increased expression of HIF1A protein CTD PMID:26073000 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hk1 hexokinase 1 decreases activity
multiple interactions
EXP Streptozocin results in decreased activity of HK1 protein
[homocastasterone analog co-treated with Streptozocin] results in increased expression of HK1 mRNA; plumbagin inhibits the reaction [Streptozocin results in decreased activity of HK1 protein]
CTD PMID:22960630, PMID:28822685 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hmgb1 high mobility group box 1 increases expression
multiple interactions
ISO Streptozocin results in increased expression of HMGB1 mRNA
manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of HMGB1 mRNA]
CTD PMID:19833897 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression
EXP [Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA; [Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein; [Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA]
Streptozocin results in increased expression of HMGCR mRNA
CTD PMID:20696151, PMID:25240712, PMID:25905778, PMID:27488359 NCBI chr 2:27,480,224...27,500,654
Ensembl chr 2:27,480,226...27,500,654
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 increases expression
multiple interactions
EXP Streptozocin results in increased expression of HMGCS2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of HMGCS2 mRNA]
CTD PMID:16684804 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 decreases activity
decreases expression
multiple interactions
increases expression
EXP
ISO
Streptozocin results in decreased activity of HMOX1 protein
Streptozocin results in decreased expression of HMOX1 mRNA; Streptozocin results in decreased expression of HMOX1 protein
[Streptozocin co-treated with sulforafan] results in increased expression of HMOX1; sulforafan inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; sulforafan inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]
HMOX1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]
Streptozocin results in increased expression of HMOX1 mRNA; Streptozocin results in increased expression of HMOX1 protein
[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein; [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein; [Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of HMOX1 protein]; chromium mesoporphyrin inhibits the reaction [[Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein]; cobaltiprotoporphyrin promotes the reaction [Streptozocin results in increased expression of HMOX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; palbinone inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Propofol inhibits the reaction [Streptozocin results in decreased activity of HMOX1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein; Streptozocin results in increased expression of and results in decreased activity of HMOX1 protein; sulforafan inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein]
CTD PMID:16309587, PMID:16595661, PMID:19019021, PMID:19190261, PMID:21439372, PMID:21457706, PMID:22023613, PMID:22531820, PMID:22675305, PMID:23453443, PMID:24508943, PMID:24810525, PMID:24967692, PMID:25541178, PMID:30817903, PMID:31173751, PMID:32202043, PMID:32662907 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hmox2 heme oxygenase 2 multiple interactions
increases response to substance
ISO cobaltiprotoporphyrin inhibits the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin]; tin mesoporphyrin promotes the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin] CTD PMID:16524951 NCBI chr10:10,990,034...11,035,493
Ensembl chr10:10,990,034...11,035,484
JBrowse link
G Hopx HOP homeobox multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of HOPX mRNA CTD PMID:25905778 NCBI chr14:33,354,803...33,362,547
Ensembl chr14:33,354,807...33,362,551
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of HSD17B10 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSD17B10 protein]
CTD PMID:21136691 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of HSD17B2 mRNA CTD PMID:25905778 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression ISO Streptozocin affects the expression of HSD17B4 mRNA CTD PMID:18583417 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 affects expression ISO Streptozocin affects the expression of HSD3B3 mRNA CTD PMID:18583417 NCBI chr 2:200,756,557...200,762,492
Ensembl chr 2:200,585,748...200,762,492
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of HSP90B1 mRNA CTD PMID:26522834 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 affects expression ISO Streptozocin affects the expression of HSPA2 mRNA CTD PMID:18583417 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
increases expression
decreases expression
EXP
ISO
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]; Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA5 protein]
[Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 protein; sulforafan inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]
CTD PMID:19634143, PMID:24967692, PMID:26522834, PMID:30980806 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of HSPA9 protein
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA9 protein]
CTD PMID:19634143 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions EXP Curcumin inhibits the reaction [Streptozocin results in increased expression of HSPB1 protein] CTD PMID:18204486 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
decreases expression
increases expression
EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPD1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of HSPD1 protein] CTD PMID:19634143, PMID:21136691 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions
decreases expression
EXP Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPE1 protein] CTD PMID:19634143 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 increases expression
multiple interactions
EXP Streptozocin results in increased expression of HSPG2 protein
Trientine inhibits the reaction [Streptozocin results in increased expression of HSPG2 protein]
CTD PMID:19634143 NCBI chr 5:155,812,096...155,913,751 JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP Streptozocin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] CTD PMID:18622176 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions EXP Streptozocin inhibits the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased activity of HTR2A protein] CTD PMID:18622176 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Iapp islet amyloid polypeptide multiple interactions
decreases expression
EXP
ISO
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of IAPP mRNA]
[octylphenol co-treated with Streptozocin] results in decreased expression of IAPP mRNA; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of IAPP mRNA]
CTD PMID:18998217, PMID:29935216 NCBI chr 4:176,509,863...176,517,903
Ensembl chr 4:176,510,696...176,516,083
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO
EXP
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; sulforafan inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; telmisartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]
Streptozocin results in increased expression of ICAM1 mRNA; Streptozocin results in increased expression of ICAM1 protein
[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; candesartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]
CTD PMID:10485912, PMID:14871415, PMID:15892581, PMID:16129698, PMID:16139267, PMID:17589825, PMID:17724226, PMID:19246972, PMID:19279317, PMID:22058332, PMID:23376009, PMID:24513509, PMID:24967692, PMID:28700904 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression EXP Streptozocin results in decreased expression of ID2 mRNA CTD PMID:25905778 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 affects expression ISO Streptozocin affects the expression of IDH2 mRNA CTD PMID:18583417 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of IFITM3 mRNA CTD PMID:25905778 NCBI chr 1:213,810,712...213,811,821
Ensembl chr 1:213,810,696...213,811,901
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
increases expression
ISO
EXP
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Dronabinol inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]; S-Nitroso-N-Acetylpenicillamine inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]
Streptozocin results in decreased expression of IFNG protein
arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]
Streptozocin results in increased expression of IFNG mRNA; Streptozocin results in increased expression of IFNG protein
CTD PMID:11357882, PMID:15862027, PMID:15892581, PMID:15975818, PMID:18789669, PMID:20053369, PMID:25541178 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
increases expression
ISO
EXP
IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]
Streptozocin results in increased expression of IGF1 protein
Streptozocin results in decreased expression of IGF1 mRNA; Streptozocin results in decreased expression of IGF1 protein
CTD PMID:7637645, PMID:9868179, PMID:11375343, PMID:23927877, PMID:25617479 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of IGF1R protein
xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of IGF1R protein]
CTD PMID:23562514 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of IGF2BP3 mRNA CTD PMID:25905778 NCBI chr 4:78,744,683...78,879,457
Ensembl chr 4:78,746,547...78,879,294
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of IGFBP2 mRNA CTD PMID:25905778 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions
increases expression
ISO 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of IGFBP3 mRNA] CTD PMID:29673160 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 increases expression ISO Streptozocin results in increased expression of IGFBP7 mRNA CTD PMID:29673160 NCBI chr14:33,010,300...33,070,193
Ensembl chr14:33,010,300...33,070,190
JBrowse link
G Igsf6 immunoglobulin superfamily, member 6 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of IGSF6 mRNA CTD PMID:25905778 NCBI chr 1:190,997,029...191,007,503
Ensembl chr 1:190,997,029...191,007,503
JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions
ISO
EXP
Streptozocin results in decreased expression of IL10 mRNA
Streptozocin results in decreased expression of IL10 mRNA; Streptozocin results in decreased expression of IL10 protein
[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]
CTD PMID:15862027, PMID:32662907 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B increases expression
multiple interactions
ISO Streptozocin results in increased expression of IL12B mRNA
Dronabinol inhibits the reaction [Streptozocin results in increased expression of IL12B mRNA]
CTD PMID:11357882 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression
EXP stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of IL17A protein]] CTD PMID:23611540 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 multiple interactions
increases expression
EXP Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of IL18 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL18 protein]
Streptozocin results in increased expression of IL18 mRNA; Streptozocin results in increased expression of IL18 protein
CTD PMID:23647015, PMID:29291386, PMID:32202043 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Streptozocin co-treated with bisphenol A] results in increased expression of IL1A mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of IL1A mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of IL1A mRNA CTD PMID:24781736 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
ISO
EXP
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]
Streptozocin results in increased expression of IL1B mRNA; Streptozocin results in increased expression of IL1B protein
Streptozocin results in decreased expression of IL1B protein
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of IL1B protein]; [Resveratrol co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B protein]; Streptozocin results in increased expression of and results in increased secretion of IL1B protein
Alendronate inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]
CTD PMID:12123627, PMID:16129698, PMID:17167242, PMID:17589825, PMID:18789669, PMID:20307516, PMID:20446767, PMID:20643114, PMID:21439372, PMID:23647015, PMID:24877639, PMID:25541178, PMID:25635252, PMID:25905778, PMID:26341651, PMID:27702591, PMID:28259689, PMID:30481507, PMID:30611788, PMID:30802477, PMID:30817903, PMID:31726037, PMID:32202043 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA CTD PMID:31726037 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1RN mRNA CTD PMID:29127188 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 multiple interactions
decreases expression
EXP arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IL2 protein] CTD PMID:20053369 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il22 interleukin 22 multiple interactions ISO IL22 protein inhibits the reaction [Streptozocin results in increased abundance of Glucose] CTD PMID:26064446 NCBI chr 7:61,236,037...61,240,502
Ensembl chr 7:61,236,037...61,240,502
JBrowse link
G Il33 interleukin 33 multiple interactions EXP 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein CTD PMID:31726037 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il4 interleukin 4 multiple interactions
decreases expression
EXP resveratrol inhibits the reaction [Streptozocin results in decreased expression of IL4] CTD PMID:25191525 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 increases expression
decreases expression
multiple interactions
increases secretion
EXP
ISO
Streptozocin results in increased expression of IL6 mRNA; Streptozocin results in increased expression of IL6 protein
Streptozocin results in decreased expression of IL6 protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein]
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; [Dietary Fats co-treated with Streptozocin co-treated with Plant Extracts] affects the expression of IL6 protein; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of IL6 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of IL6 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein; [Propolis co-treated with Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein; [Propolis co-treated with Streptozocin] results in increased secretion of IL6 protein; [Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; caryophyllene inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Melatonin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein]; Propolis inhibits the reaction [Streptozocin results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; SMe1EC2 promotes the reaction [Streptozocin results in increased expression of IL6 protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 protein]
CTD PMID:17167242, PMID:17854708, PMID:18999900, PMID:20307516, PMID:20643114, PMID:21439094, PMID:21439372, PMID:21457706, PMID:21912612, PMID:24760747, PMID:24877639, PMID:26341651, PMID:26748309, PMID:27769711, PMID:28700904, PMID:28904557, PMID:29409856, PMID:29988851, PMID:30481507, PMID:30611788, PMID:30802477, PMID:30817903, PMID:31323227, PMID:31400774, PMID:31696645, PMID:31726037, PMID:32554039 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6st interleukin 6 signal transducer affects expression ISO Streptozocin affects the expression of IL6ST mRNA CTD PMID:26073000 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Ilk integrin-linked kinase multiple interactions
increases activity
EXP notoginsenoside R1 inhibits the reaction [Streptozocin results in increased activity of ILK protein] CTD PMID:25503068 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Impa2 inositol monophosphatase 2 increases expression
multiple interactions
EXP Streptozocin results in increased expression of IMPA2 mRNA
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of IMPA2 mRNA]
CTD PMID:16684804 NCBI chr18:63,016,577...63,050,123
Ensembl chr18:63,016,577...63,047,781
JBrowse link
G Inhbb inhibin subunit beta B multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of INHBB mRNA CTD PMID:29127188 NCBI chr13:35,436,532...35,442,222
Ensembl chr13:35,436,532...35,442,222
JBrowse link
G Ins2 insulin 2 multiple interactions
decreases expression
ISO
EXP
ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein]; INS protein inhibits the reaction [Streptozocin results in decreased expression of NES mRNA]; Resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]
INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA]; INS protein inhibits the reaction [Streptozocin results in increased expression of NPY mRNA]; INS protein promotes the reaction [Streptozocin results in decreased activity of SOD2 protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased expression of PPARG mRNA]
Streptozocin results in decreased expression of INS protein
INS protein inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein]
CTD PMID:11216864, PMID:19388005, PMID:20219977, PMID:22940631, PMID:23884884, PMID:25808216, PMID:27542954 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insig2 insulin induced gene 2 decreases expression EXP Streptozocin results in decreased expression of INSIG2 mRNA CTD PMID:25905778 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Insr insulin receptor affects expression
multiple interactions
decreases expression
increases expression
decreases phosphorylation
EXP
ISO
Streptozocin affects the expression of INSR protein
[Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR protein; Estradiol affects the reaction [Streptozocin affects the expression of INSR protein]; Melatonin inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR protein]; Progesterone affects the reaction [Streptozocin affects the expression of INSR protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of INSR protein]
resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]
Streptozocin results in decreased expression of INSR mRNA
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of INSR protein; Metformin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; puerarin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]
Streptozocin results in increased expression of INSR mRNA
Streptozocin results in decreased phosphorylation of INSR protein
CTD PMID:9243097, PMID:17068109, PMID:18331706, PMID:19705549, PMID:21439094, PMID:23562514, PMID:23927877, PMID:25446853, PMID:25808216, PMID:26522834, PMID:29614383 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of IRF1 mRNA CTD PMID:25905778 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions
decreases expression
ISO
EXP
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein; [Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein; Metformin inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Metformin promotes the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein]
Streptozocin results in decreased expression of IRS1 mRNA; Streptozocin results in decreased expression of IRS1 protein
[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]
CTD PMID:23927877, PMID:24923654, PMID:26071184, PMID:26522834, PMID:31743741 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions
decreases expression
EXP
ISO
[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS2 mRNA]
[Streptozocin co-treated with bisphenol A] results in decreased expression of IRS2 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of IRS2 mRNA
Streptozocin results in decreased expression of IRS2 mRNA; Streptozocin results in decreased expression of IRS2 protein
CTD PMID:24923654, PMID:26071184, PMID:27417257, PMID:29935216 NCBI chr16:83,824,515...83,848,569
Ensembl chr16:83,824,430...83,848,684
JBrowse link
G Itga3 integrin subunit alpha 3 multiple interactions
decreases expression
ISO
EXP
notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 protein]
Streptozocin results in decreased expression of ITGA3 mRNA; Streptozocin results in decreased expression of ITGA3 protein
CTD PMID:25503068 NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
JBrowse link
G Itgal integrin subunit alpha L multiple interactions
increases expression
EXP [resveratrol co-treated with Streptozocin] results in increased expression of ITGAL mRNA; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAL protein] CTD PMID:16129698, PMID:25905778 NCBI chr 1:198,744,053...198,781,745
Ensembl chr 1:198,744,050...198,781,750
JBrowse link
G Itgam integrin subunit alpha M multiple interactions
increases expression
EXP Ibuprofen inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]
Streptozocin results in increased expression of ITGAM mRNA; Streptozocin results in increased expression of ITGAM protein
CTD PMID:16129698, PMID:24333387 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Itgav integrin subunit alpha V affects expression ISO Streptozocin affects the expression of ITGAV mRNA CTD PMID:26073000 NCBI chr 3:71,113,269...71,205,958
Ensembl chr 3:71,114,100...71,202,411
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression
multiple interactions
EXP
ISO
Streptozocin results in decreased expression of ITGB1 mRNA; Streptozocin results in decreased expression of ITGB1 protein
notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 protein]
CTD PMID:25503068 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions
increases expression
EXP [resveratrol co-treated with Streptozocin] results in increased expression of ITGB2 mRNA; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGB2 protein] CTD PMID:16129698, PMID:25905778 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 increases expression
multiple interactions
ISO Streptozocin results in increased expression of ITPR3 mRNA
[bisphenol A co-treated with Streptozocin] results in increased expression of ITPR3 mRNA; [octylphenol co-treated with Streptozocin] results in increased expression of ITPR3 mRNA
CTD PMID:29935216 NCBI chr20:5,645,894...5,711,702
Ensembl chr20:5,646,097...5,711,702
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP
ISO
resveratrol inhibits the reaction [Streptozocin results in increased expression of JUN protein]
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]; Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]
CTD PMID:26499206, PMID:28478229 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 increases expression ISO Streptozocin results in increased expression of KCNN2 protein CTD PMID:30635400 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Kdr kinase insert domain receptor multiple interactions
increases expression
EXP
ISO
Simvastatin inhibits the reaction [Streptozocin results in increased expression of KDR mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein]; Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein
[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein]
Streptozocin results in increased expression of KDR mRNA; Streptozocin results in increased expression of KDR protein
CTD PMID:15643138, PMID:20821229, PMID:27097221 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions
increases expression
decreases expression
EXP [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]
Streptozocin results in increased expression of KEAP1 mRNA; Streptozocin results in increased expression of KEAP1 protein
CTD PMID:21439372, PMID:30817903, PMID:32662907 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kl Klotho decreases expression
multiple interactions
EXP Streptozocin results in decreased expression of KL
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of KL]
CTD PMID:24136780 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of KLF4 mRNA CTD PMID:25905778 NCBI chr 5:72,283,311...72,287,669
Ensembl chr 5:72,283,313...72,287,669
JBrowse link
G Klk1 kallikrein 1 multiple interactions
increases expression
EXP
ISO
KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAL protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGB2 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]
Streptozocin results in increased expression of KLK1 mRNA
CTD PMID:16129698, PMID:19516248 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Kng2 kininogen 2 multiple interactions
increases response to substance
EXP Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of Dinoprostone]; Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of TAC1 protein modified form]
Streptozocin results in increased susceptibility to KNG1 protein modified form
CTD PMID:20832942 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Krt19 keratin 19 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of KRT19 mRNA CTD PMID:25905778 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Kynu kynureninase multiple interactions EXP [resveratrol co-treated with Streptozocin] results in decreased expression of KYNU mRNA CTD PMID:25905778 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link
G Lap3 leucine aminopeptidase 3 affects expression ISO Streptozocin affects the expression of LAP3 mRNA CTD PMID:18583417 NCBI chr14:70,102,813...70,121,797
Ensembl chr14:70,102,814...70,121,797
JBrowse link
G Laptm5 lysosomal protein transmembrane 5 multiple interactions EXP [resveratrol co-treated with Streptozocin] results in increased expression of LAPTM5 mRNA CTD PMID:25905778 NCBI chr 5:149,015,793...149,069,719
Ensembl chr 5:149,047,681...149,069,719
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP [Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein] CTD PMID:20696151, PMID:25240712 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP 2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-6-hydroxymethyltetrahydro-2H-pyran-3,4,5-triol inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; [Resveratrol co-treated with Streptozocin] results in increased expression of LCN2 mRNA; [Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein; [Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein] CTD PMID:25905778, PMID:26474837, PMID:30551545 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Ldhb lactate dehydrogenase B increases expression
multiple interactions
EXP Streptozocin results in increased expression of LDHB protein
Trientine inhibits the reaction [Streptozocin results in increased expression of LDHB protein]
CTD PMID:19634143, PMID:21136691 NCBI chr 4:176,701,980...176,719,999
Ensembl chr 4:176,701,983...176,720,012
JBrowse link
G Lep leptin multiple interactions EXP
ISO
[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein]
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein]; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein]
CTD PMID:24854284, PMID:29988851, PMID:32410268 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor multiple interactions ISO [Streptozocin co-treated with Dietary Fats] results in increased expression of LEPR mRNA CTD PMID:29127188 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lgals3 galectin 3 multiple interactions
increases expression
EXP [resveratrol co-treated with Streptozocin] results in increased expression of LGALS3 mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LGALS3 mRNA] CTD PMID:16684804, PMID:25905778 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537