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ONTOLOGY REPORT - ANNOTATIONS


Term:monoethylglycinexylidide
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Accession:CHEBI:222828 term browser browse the term
Definition:Amino acid amide formed from 2,6-dimethylaniline and N-ethylglycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function.
Synonyms:exact_synonym: N-(2,6-dimethylphenyl)-N(2)-ethylglycinamide
 related_synonym: 2-Ethylamino-2',6'-acetoxylidide;   2-Ethylamino-2,6-acetoxylidine;   Ethylglycylxylidide;   Formula=C12H18N2O;   InChI=1S/C12H18N2O/c1-4-13-8-11(15)14-12-9(2)6-5-7-10(12)3/h5-7,13H,4,8H2,1-3H3,(H,14,15);   InChIKey=WRMRXPASUROZGT-UHFFFAOYSA-N;   Lidocaine N-de-ethylated metabolite;   N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide;   N-Ethylglycinexylidide;   SMILES=CCNCC(=O)Nc1c(C)cccc1C;   norlidocaine;   omega-(ethylamino)-2',6'-dimethylacetanilide
 xref: Beilstein:2417108 "Beilstein";   CAS:7728-40-7 "ChemIDplus";   CAS:7728-40-7 "KEGG COMPOUND";   CAS:7728-40-7 "NIST Chemistry WebBook";   HMDB:HMDB0060656;   KEGG:C16561
 xref_mesh: MESH:C001173
 xref: PMID:17296334 "Europe PMC";   PMID:22212047 "Europe PMC";   PMID:22452841 "Europe PMC";   PMID:22468031 "Europe PMC";   PMID:7071904 "Europe PMC";   PMID:9989796 "Europe PMC";   Reaxys:2417108 "Reaxys"


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monoethylglycinexylidide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ces1d carboxylesterase 1D JBrowse link 19 15,195,514 15,239,827 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        biochemical role 19178
          metabolite 19150
            xenobiotic metabolite 13829
              human xenobiotic metabolite 13017
                drug metabolite 4393
                  monoethylglycinexylidide 1
                    monoethylglycinexylidide hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19728
    subatomic particle 19724
      composite particle 19724
        hadron 19724
          baryon 19724
            nucleon 19724
              atomic nucleus 19724
                atom 19724
                  main group element atom 19610
                    p-block element atom 19610
                      carbon group element atom 19501
                        carbon atom 19494
                          organic molecular entity 19494
                            organic group 18413
                              organic divalent group 18404
                                organodiyl group 18404
                                  carbonyl group 18293
                                    carbonyl compound 18293
                                      carboxylic acid 17960
                                        carboacyl group 17072
                                          univalent carboacyl group 17072
                                            carbamoyl group 16801
                                              carboxamide 16801
                                                amino acid amide 883
                                                  monoethylglycinexylidide 1
                                                    monoethylglycinexylidide hydrochloride 0
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