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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:alkaline earth metal atom
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Accession:CHEBI:22313 term browser browse the term
Synonyms:related_synonym: Erdalkalimetall;   Erdalkalimetalle;   alkaline-earth metal;   alkaline-earth metals;   metal alcalino-terreux;   metal alcalinoterreo;   metales alcalinoterreos;   metaux alcalino-terreux


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barium chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP [barium chloride results in increased abundance of Barium] which results in decreased activity of ACHE protein CTD PMID:31407482 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Alb albumin multiple interactions
increases secretion
EXP Plant Extracts inhibits the reaction [barium chloride results in increased secretion of ALB protein] CTD PMID:26732703 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Cat catalase multiple interactions
decreases activity
EXP [barium chloride results in increased abundance of Barium] which results in decreased activity of CAT protein; Plant Extracts inhibits the reaction [barium chloride results in decreased activity of CAT protein] CTD PMID:26732703, PMID:31407482 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
EXP barium chloride results in increased expression of IL1B mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL1B mRNA]
CTD PMID:26732703 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
EXP barium chloride results in increased expression of IL6 mRNA
[barium chloride results in increased abundance of Barium] which results in increased expression of IL6 protein; Plant Extracts inhibits the reaction [barium chloride results in increased expression of IL6 mRNA]
CTD PMID:26732703, PMID:31407482 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions ISO barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions EXP barium chloride inhibits the reaction [KCNJ2 protein results in increased transport of Potassium] CTD PMID:11087224 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Kcnk3 potassium two pore domain channel subfamily K member 3 decreases activity EXP barium chloride results in decreased activity of KCNK3 protein CTD PMID:16020457 NCBI chr 6:27,154,274...27,190,209
Ensembl chr 6:27,151,612...27,190,132
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO barium chloride results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Mt1 metallothionein 1 increases expression
multiple interactions
EXP barium chloride results in increased expression of MT1 mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of MT1 mRNA]
CTD PMID:26732703 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A increases expression
multiple interactions
EXP barium chloride results in increased expression of MT2A mRNA
Plant Extracts inhibits the reaction [barium chloride results in increased expression of MT2A mRNA]
CTD PMID:26732703 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Serpine1 serpin family E member 1 increases secretion EXP barium chloride results in increased secretion of SERPINE1 protein CTD PMID:21596853 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
multiple interactions
EXP barium chloride results in decreased expression of SOD2 mRNA
Plant Extracts inhibits the reaction [barium chloride results in decreased expression of SOD2 mRNA]
CTD PMID:26732703 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Stx1a syntaxin 1A multiple interactions
affects localization
EXP Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]; STX1A protein modified form inhibits the reaction [Propofol inhibits the reaction [barium chloride affects the localization of STX1A protein]] CTD PMID:29320738 NCBI chr12:24,682,050...24,710,002
Ensembl chr12:24,682,041...24,710,019
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP Plant Extracts inhibits the reaction [barium chloride results in increased expression of TNF mRNA] CTD PMID:26732703 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [barium chloride results in increased abundance of Barium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
barium ion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmbs hydroxymethylbilane synthase decreases activity EXP Barium ion decreases activity of purified Hmbs protein RGD PMID:6732900 RGD:25394584 NCBI chr 8:48,667,278...48,674,673
Ensembl chr 8:48,667,275...48,674,748
JBrowse link
barium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin increases expression EXP Barium Sulfate results in increased expression of ALB mRNA CTD PMID:29463257 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression EXP Barium Sulfate results in increased expression of BIRC5 mRNA CTD PMID:29463257 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression EXP Barium Sulfate results in increased expression of CCL11 mRNA CTD PMID:29463257 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion
increases expression
EXP Barium Sulfate results in increased secretion of CCL2 protein
Barium Sulfate results in increased expression of CCL2 mRNA
CTD PMID:29463257 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 affects expression EXP Barium Sulfate affects the expression of CCL20 mRNA CTD PMID:29463257 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases expression EXP Barium Sulfate results in increased expression of CCL22 mRNA CTD PMID:29463257 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
JBrowse link
G Ccl24 C-C motif chemokine ligand 24 increases expression EXP Barium Sulfate results in increased expression of CCL24 mRNA CTD PMID:29463257 NCBI chr12:24,131,529...24,152,626
Ensembl chr12:24,148,567...24,152,625
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression EXP Barium Sulfate results in decreased expression of CCL4 mRNA CTD PMID:29463257 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression EXP Barium Sulfate results in increased expression of CCL7 mRNA CTD PMID:29463257 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression EXP Barium Sulfate results in increased expression of CCR2 mRNA CTD PMID:29463257
G Cd40lg CD40 ligand decreases expression EXP Barium Sulfate results in decreased expression of CD40LG mRNA CTD PMID:29463257 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression EXP Barium Sulfate results in increased expression of CXCL9 mRNA CTD PMID:29463257 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 increases expression EXP Barium Sulfate results in increased expression of CXCR3 mRNA CTD PMID:29463257 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP Barium Sulfate results in increased expression of CYP4A1 mRNA CTD PMID:11124224 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases expression EXP Barium Sulfate results in increased expression of CYP4A2 mRNA CTD PMID:11124224 NCBI chr 5:134,196,910...134,207,888
Ensembl chr 5:134,196,912...134,207,863
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 increases expression EXP Barium Sulfate results in increased expression of CYP4A3 mRNA CTD PMID:11124224 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 increases expression EXP Barium Sulfate results in increased expression of CYP4F1 mRNA CTD PMID:14644421 NCBI chr 7:15,179,472...15,191,113
Ensembl chr 7:15,179,467...15,190,796
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 increases expression EXP Barium Sulfate results in increased expression of CYP4F4 mRNA CTD PMID:14644421 NCBI chr 7:14,891,062...14,907,250
Ensembl chr 7:14,891,001...14,907,305
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 increases expression EXP Barium Sulfate results in increased expression of CYP4F6 mRNA CTD PMID:14644421 NCBI chr 7:15,198,950...15,225,547
Ensembl chr 7:15,198,940...15,225,410
JBrowse link
G Exo1 exonuclease 1 affects expression EXP Barium Sulfate affects the expression of EXO1 mRNA CTD PMID:29463257 NCBI chr13:93,936,989...93,962,749
Ensembl chr13:93,939,022...93,960,342
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression EXP Barium Sulfate results in decreased expression of FABP4 mRNA CTD PMID:29463257 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 decreases expression EXP Barium Sulfate results in decreased expression of HBA1 mRNA CTD PMID:29463257 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Il2rb interleukin 2 receptor subunit beta decreases expression EXP Barium Sulfate results in decreased expression of IL2RB mRNA CTD PMID:29463257 NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238
JBrowse link
G Il6 interleukin 6 increases expression ISO Barium Sulfate results in increased expression of IL6 protein CTD PMID:11403239 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Krt1 keratin 1 increases expression EXP Barium Sulfate results in increased expression of KRT1 mRNA CTD PMID:29463257 NCBI chr 7:143,448,318...143,453,544
Ensembl chr 7:143,448,318...143,453,544
JBrowse link
G Lig4 DNA ligase 4 increases expression EXP Barium Sulfate results in increased expression of LIG4 mRNA CTD PMID:29463257 NCBI chr16:85,331,771...85,339,496
Ensembl chr16:85,331,866...85,337,769
JBrowse link
G Lpo lactoperoxidase increases expression EXP Barium Sulfate results in increased expression of LPO mRNA; Barium Sulfate results in increased expression of LPO protein CTD PMID:29463257 NCBI chr10:75,100,385...75,120,247
Ensembl chr10:75,100,385...75,120,247
JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression EXP Barium Sulfate results in increased expression of MMP12 mRNA; Barium Sulfate results in increased expression of MMP12 protein CTD PMID:29463257 NCBI chr 8:5,594,717...5,616,494
Ensembl chr 8:5,606,592...5,616,493
JBrowse link
G Mutyh mutY DNA glycosylase increases expression EXP Barium Sulfate results in increased expression of MUTYH mRNA CTD PMID:29463257 NCBI chr 5:135,663,328...135,675,348
Ensembl chr 5:135,663,371...135,675,344
JBrowse link
G Ngb neuroglobin decreases expression EXP Barium Sulfate results in decreased expression of NGB mRNA CTD PMID:29463257 NCBI chr 6:111,126,259...111,131,699
Ensembl chr 6:111,126,261...111,132,320
JBrowse link
G Noxo1 NADPH oxidase organizer 1 increases expression EXP Barium Sulfate results in increased expression of NOXO1 mRNA CTD PMID:29463257 NCBI chr10:14,062,331...14,066,918
Ensembl chr10:14,062,331...14,066,918
JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like increases expression EXP Barium Sulfate results in increased expression of OPCML mRNA CTD PMID:29463257 NCBI chr 8:28,842,202...29,967,300
Ensembl chr 8:29,453,643...29,962,825
JBrowse link
G Pf4 platelet factor 4 increases expression EXP Barium Sulfate results in increased expression of PF4 mRNA CTD PMID:29463257 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Scd stearoyl-CoA desaturase affects expression EXP Barium Sulfate affects the expression of SCD1 mRNA CTD PMID:29463257 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Tcf21 transcription factor 21 decreases expression EXP Barium Sulfate results in decreased expression of TCF21 mRNA CTD PMID:29463257 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
JBrowse link
G Thbs2 thrombospondin 2 increases expression EXP Barium Sulfate results in increased expression of THBS2 mRNA CTD PMID:29463257 NCBI chr 1:56,653,929...56,683,571
Ensembl chr 1:56,653,938...56,683,731
JBrowse link
G Top2a DNA topoisomerase II alpha increases expression EXP Barium Sulfate results in increased expression of TOP2A mRNA CTD PMID:29463257 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Txnip thioredoxin interacting protein decreases expression EXP Barium Sulfate results in decreased expression of TXNIP mRNA CTD PMID:29463257 NCBI chr 2:198,683,168...198,686,971
Ensembl chr 2:198,683,159...198,686,974
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 increases expression EXP Barium Sulfate results in increased expression of XRCC2 mRNA CTD PMID:29463257 NCBI chr 4:5,842,013...5,860,516
Ensembl chr 4:5,841,998...5,860,527
JBrowse link
barium(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP [barium chloride results in increased abundance of Barium] which results in decreased activity of ACHE protein CTD PMID:31407482 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions ISO ADRA1A protein promotes the reaction [TRPC6 protein results in increased transport of Barium] CTD PMID:11179201 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A increases transport EXP CACNA1A protein results in increased transport of Barium CTD PMID:11313431 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B affects transport
increases transport
multiple interactions
ISO CACNA1B gene polymorphism affects the transport of Barium
CACNA1B protein results in increased transport of Barium
[GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; Cadmium Chloride inhibits the reaction [CACNA1B protein results in increased transport of Barium]
CTD PMID:11007869, PMID:11756491, PMID:14559144 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases transport EXP CACNA1C protein results in increased transport of Barium CTD PMID:17569661 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D affects transport
multiple interactions
increases transport
ISO
EXP
CACNA1D protein affects the transport of Barium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Barium]
CACNA1D protein results in increased transport of Barium
CTD PMID:15357422, PMID:17567805, PMID:27798183 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases transport
multiple interactions
affects transport
ISO
EXP
CACNA1E mRNA alternative form results in increased transport of Barium; CACNA1E protein results in increased transport of Barium
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; 4-O-methyl-12-O-tetradecanoylphorbol 13-acetate affects the reaction [CACNA1E protein results in increased transport of Barium]; Atropine inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Heparin affects the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; Isradipine inhibits the reaction [CACNA1E protein results in increased transport of Barium]; Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Barium]; omega-conotoxin-MVIIC promotes the reaction [Isradipine inhibits the reaction [CACNA1E protein results in increased transport of Barium]]; Ro 31-8425 inhibits the reaction [4-O-methyl-12-O-tetradecanoylphorbol 13-acetate affects the reaction [CACNA1E protein results in increased transport of Barium]]; Ro 31-8425 inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]; SNX 482 inhibits the reaction [CACNA1E protein results in increased transport of Barium]
SNX 482 inhibits the reaction [CACNA1E mRNA alternative form results in increased transport of Barium]
CACNA1E protein affects the transport of Barium
CTD PMID:10627594, PMID:10669483, PMID:11102459, PMID:11179973, PMID:12663092, PMID:15245474 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F multiple interactions
increases transport
ISO 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester promotes the reaction [CACNA1F protein results in increased transport of Barium]; Diltiazem inhibits the reaction [CACNA1F protein results in increased transport of Barium]; Isradipine inhibits the reaction [CACNA1F protein results in increased transport of Barium]; Verapamil inhibits the reaction [CACNA1F protein results in increased transport of Barium] CTD PMID:14744918 NCBI chr  X:15,712,709...15,741,135
Ensembl chr  X:15,712,713...15,741,103
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G increases transport
multiple interactions
ISO CACNA1G mRNA alternative form results in increased transport of Barium; CACNA1G protein results in increased transport of Barium
Cerium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Erbium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Gadolinium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Holmium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Lanthanum inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Neodymium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Scandium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Ytterbium inhibits the reaction [CACNA1G protein results in increased transport of Barium]; Yttrium inhibits the reaction [CACNA1G protein results in increased transport of Barium]
CTD PMID:11179973, PMID:12163980 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases transport ISO CACNA1H mRNA alternative form results in increased transport of Barium CTD PMID:11179973 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I increases transport ISO CACNA1I mRNA alternative form results in increased transport of Barium CTD PMID:11179973 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 affects transport
increases transport
ISO
EXP
CACNA2D1 protein affects the transport of Barium
CACNA2D1 protein results in increased transport of Barium
CTD PMID:11313431, PMID:15245474, PMID:15474003 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 multiple interactions ISO CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Barium] CTD PMID:27798183 NCBI chr 8:116,154,661...116,285,643
Ensembl chr 8:116,154,736...116,284,985
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 affects transport ISO CACNB3 protein affects the transport of Barium CTD PMID:15245474 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 affects transport ISO
EXP
CACNB4 protein affects the transport of Barium CTD PMID:11313431, PMID:15245474 NCBI chr 3:37,950,846...38,211,478
Ensembl chr 3:37,955,069...38,090,526
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 affects transport ISO CACNG2 protein affects the transport of Barium CTD PMID:11313431 NCBI chr 7:119,228,112...119,353,332
Ensembl chr 7:119,228,102...119,352,605
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 affects transport ISO CACNG3 protein affects the transport of Barium CTD PMID:11313431 NCBI chr 1:192,613,766...192,708,371
Ensembl chr 1:192,613,372...192,709,078
JBrowse link
G Cat catalase multiple interactions EXP [barium chloride results in increased abundance of Barium] which results in decreased activity of CAT protein CTD PMID:31407482 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit multiple interactions ISO 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 1-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; [CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium; Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]; crotonyl alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; isobutyl alcohol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; tert-Butyl Alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 NCBI chr15:42,808,897...42,825,179
Ensembl chr15:42,808,897...42,825,179
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Barium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Barium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions EXP [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Barium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Barium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions ISO 1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 1-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; 2-Propanol promotes the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; [CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium; Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]; crotonyl alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; isobutyl alcohol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; n-pentanol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]]; tert-Butyl Alcohol inhibits the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] CTD PMID:11821649 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
decreases transport
EXP 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester inhibits the reaction [DRD2 protein results in decreased transport of Barium]; [DRD2 protein affects the abundance of Calcium] which results in decreased transport of Barium; [DRD2 protein results in increased activity of PLCB1 protein] which results in decreased transport of Barium; DRD2 protein affects the reaction [N-n-propylnorapomorphine analog results in decreased transport of Barium]; DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]; Nifedipine inhibits the reaction [DRD2 protein affects the reaction [Quinpirole results in decreased transport of Barium]] CTD PMID:11124974 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G F2 coagulation factor II increases uptake
multiple interactions
ISO F2 protein results in increased uptake of Barium
Nickel inhibits the reaction [F2 protein results in increased uptake of Barium]
CTD PMID:2125206 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO Barium inhibits the reaction [F2RL1 protein results in increased transport of Chlorides]; F2RL1 protein affects the reaction [1-oleoyl-2-acetoyl-sn-glycerol results in increased transport of Barium] CTD PMID:11804840, PMID:16123040 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 decreases activity ISO Barium results in decreased activity of FXYD2 protein CTD PMID:11533133 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
G Gnb1 G protein subunit beta 1 multiple interactions ISO [GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Gnb2 G protein subunit beta 2 multiple interactions ISO [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr12:22,229,079...22,234,096
Ensembl chr12:22,229,079...22,234,096
JBrowse link
G Gnb3 G protein subunit beta 3 multiple interactions ISO [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 4:157,352,558...157,359,237
Ensembl chr 4:157,352,372...157,358,262
JBrowse link
G Gnb4 G protein subunit beta 4 multiple interactions ISO [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 2:118,978,965...119,007,877
Ensembl chr 2:118,978,973...119,007,835
JBrowse link
G Gnb5 G protein subunit beta 5 multiple interactions ISO [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 8:82,248,951...82,286,493
Ensembl chr 8:82,257,849...82,285,184
JBrowse link
G Gng2 G protein subunit gamma 2 multiple interactions ISO [GNB1 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB5 protein binds to GNG2 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr15:4,748,242...4,853,555
Ensembl chr15:4,850,122...4,853,555
JBrowse link
G Gng3 G protein subunit gamma 3 multiple interactions ISO [GNB1 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNG3 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 1:225,033,921...225,035,687
Ensembl chr 1:225,033,921...225,035,687
JBrowse link
G Gngt1 G protein subunit gamma transducin 1 multiple interactions ISO [GNB1 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB2 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB3 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium]; [GNB4 protein binds to GNGT1 protein] inhibits the reaction [CACNA1B protein results in increased transport of Barium] CTD PMID:11007869 NCBI chr 4:28,972,339...28,975,419
Ensembl chr 4:28,972,434...28,975,419
JBrowse link
G Il6 interleukin 6 multiple interactions EXP [barium chloride results in increased abundance of Barium] which results in increased expression of IL6 protein CTD PMID:31407482 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kcna10 potassium voltage-gated channel subfamily A member 10 multiple interactions ISO Barium inhibits the reaction [KCNA10 protein results in increased transport of Potassium] CTD PMID:10836990 NCBI chr 2:209,920,590...209,932,665
Ensembl chr 2:209,920,590...209,932,665
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 multiple interactions ISO Barium results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 decreases activity ISO Barium results in decreased activity of KCNH1 protein CTD PMID:10896755 NCBI chr13:110,920,712...111,232,291
Ensembl chr13:110,920,737...111,232,269
JBrowse link
G Kcnh3 potassium voltage-gated channel subfamily H member 3 multiple interactions ISO Barium binds to and results in decreased activity of KCNH3 protein CTD PMID:12193184 NCBI chr 7:140,788,987...140,910,426
Ensembl chr 7:140,788,987...140,910,422
JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 decreases activity EXP Barium results in decreased activity of KCNJ10 protein CTD PMID:16331678, PMID:17978865 NCBI chr13:90,722,945...90,753,338
Ensembl chr13:90,723,092...90,752,581
JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 multiple interactions ISO Barium inhibits the reaction [KCNJ12 protein results in increased transport of Potassium] CTD PMID:15958527 NCBI chr10:47,282,208...47,343,501
Ensembl chr10:47,281,786...47,341,411
JBrowse link
G Kcnj14 potassium inwardly-rectifying channel, subfamily J, member 14 multiple interactions ISO
EXP
Barium inhibits the reaction [KCNJ14 protein results in increased transport of Potassium] CTD PMID:10938328, PMID:17347781 NCBI chr 1:101,805,531...101,809,544
Ensembl chr 1:101,805,531...101,809,544
JBrowse link
G Kcnj15 potassium inwardly-rectifying channel, subfamily J, member 15 decreases activity ISO Barium results in decreased activity of KCNJ15 protein CTD PMID:15328350 NCBI chr11:35,545,185...35,588,517
Ensembl chr11:35,568,182...35,585,390
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 multiple interactions
decreases activity
ISO Barium inhibits the reaction [KCNJ2 protein results in increased transport of Potassium]
Barium results in decreased activity of KCNJ2 protein
CTD PMID:12598232, PMID:15958527, PMID:17347781, PMID:17699636 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 decreases activity
multiple interactions
ISO Barium results in decreased activity of KCNJ4 protein
Barium inhibits the reaction [KCNJ4 protein results in increased transport of Potassium]
CTD PMID:12598232, PMID:17091215 NCBI chr 7:120,717,378...120,744,602
Ensembl chr 7:120,717,375...120,744,602
JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 multiple interactions ISO Barium inhibits the reaction [KCNK1 protein results in increased transport of Potassium]; Barium inhibits the reaction [KCNK1 protein results in increased transport of Sodium] CTD PMID:16847696 NCBI chr19:58,823,836...58,862,926
Ensembl chr19:58,823,814...58,862,926
JBrowse link
G Kcnk18 potassium two pore domain channel subfamily K member 18 multiple interactions ISO Barium inhibits the reaction [KCNK18 protein results in increased transport of Potassium] CTD PMID:12754259 NCBI chr 1:280,383,579...280,397,784
Ensembl chr 1:280,383,579...280,397,784
JBrowse link
G Kcnk9 potassium two pore domain channel subfamily K member 9 multiple interactions EXP Barium inhibits the reaction [KCNK9 protein results in increased transport of Potassium] CTD PMID:10734076 NCBI chr 7:113,894,918...113,938,397
Ensembl chr 7:113,903,557...113,937,941
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 multiple interactions ISO Barium results in decreased activity of [KCNQ1 protein binds to KCNE1 protein] CTD PMID:16909339 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Mir30a microRNA 30a multiple interactions ISO [Air Pollutants, Occupational results in increased abundance of Barium] which results in decreased expression of MIR30A mRNA CTD PMID:27506416 NCBI chr 9:29,542,635...29,542,705
Ensembl chr 9:29,542,635...29,542,705
JBrowse link
G Mmp14 matrix metallopeptidase 14 increases expression ISO Barium results in increased expression of MMP14 protein CTD PMID:23804419 NCBI chr15:33,074,441...33,083,666
Ensembl chr15:33,074,441...33,083,655
JBrowse link
G Npr3 natriuretic peptide receptor 3 multiple interactions ISO Barium inhibits the reaction [NPR3 protein affects the reaction [Enterotoxins affects the transport of Potassium]]; Barium inhibits the reaction [NPR3 protein affects the reaction [guanylin affects the transport of Potassium]] CTD PMID:11889121 NCBI chr 2:61,883,946...61,950,291
Ensembl chr 2:61,888,950...61,949,926
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO P2RX7 protein affects the reaction [Adenosine Triphosphate results in increased transport of Barium] CTD PMID:11003599 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Plcb1 phospholipase C beta 1 multiple interactions EXP [DRD2 protein results in increased activity of PLCB1 protein] which results in decreased transport of Barium CTD PMID:11124974 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
G Ptk2 protein tyrosine kinase 2 increases phosphorylation ISO Barium results in increased phosphorylation of PTK2 protein CTD PMID:23804419 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions ISO Barium inhibits the reaction [SGK1 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 multiple interactions ISO Barium inhibits the reaction [SGK2 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr 3:159,361,313...159,385,843
Ensembl chr 3:159,368,273...159,384,775
JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 multiple interactions ISO Barium inhibits the reaction [SGK3 protein results in increased transport of Potassium] CTD PMID:12590200 NCBI chr 5:9,046,889...9,094,740
Ensembl chr 5:9,048,614...9,094,616
JBrowse link
G Slc12a4 solute carrier family 12 member 4 multiple interactions ISO Barium inhibits the reaction [SLC12A4 protein results in increased transport of Potassium] CTD PMID:11703599 NCBI chr19:37,917,003...37,938,952
Ensembl chr19:37,917,014...37,938,857
JBrowse link
G Slc12a7 solute carrier family 12 member 7 decreases activity ISO Barium results in decreased activity of SLC12A7 protein CTD PMID:10913127 NCBI chr 1:32,086,755...32,167,950
Ensembl chr 1:32,086,755...32,141,036
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Barium promotes the reaction [SLC22A12 protein results in increased uptake of p-Aminohippuric Acid] CTD PMID:15284287 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
G Slc22a3 solute carrier family 22 member 3 multiple interactions ISO Barium inhibits the reaction [SLC22A3 protein results in increased uptake of Tetraethylammonium] CTD PMID:10966924 NCBI chr 1:48,433,079...48,521,261
Ensembl chr 1:48,433,079...48,521,256
JBrowse link
G Slc8a1 solute carrier family 8 member A1 affects transport ISO SLC8A1 protein affects the transport of Barium CTD PMID:17560225 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Barium inhibits the reaction [TNF protein results in increased transport of Potassium] CTD PMID:10783394 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 multiple interactions
increases transport
ISO 1-oleoyl-2-acetylglycerol promotes the reaction [TRPC3 protein results in increased transport of Barium]
1-oleoyl-2-acetoyl-sn-glycerol affects the reaction [TRPC3 protein results in increased transport of Barium]
CTD PMID:11042129, PMID:16055711 NCBI chr 2:123,329,954...123,467,574
Ensembl chr 2:123,329,875...123,407,496
JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 multiple interactions
increases transport
ISO TRPC4 protein affects the reaction [Carbachol results in increased transport of Barium]
TRPC4 protein results in increased transport of Barium
CTD PMID:11042129, PMID:11830588 NCBI chr 2:143,433,102...143,605,757
Ensembl chr 2:143,475,323...143,604,972
JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 multiple interactions
increases transport
affects transport
ISO 1-oleoyl-2-acetoyl-sn-glycerol affects the reaction [TRPC6 protein affects the transport of Barium]; ADRA1A protein promotes the reaction [TRPC6 protein results in increased transport of Barium] CTD PMID:11179201, PMID:16055711 NCBI chr 8:6,811,543...6,917,534
Ensembl chr 8:6,811,543...6,917,535
JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 multiple interactions ISO TRPM6 protein affects the reaction [1-oleoyl-2-acetylglycerol results in increased transport of Barium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Barium] CTD PMID:11988098 NCBI chr 1:234,478,908...234,631,264
Ensembl chr 1:234,479,289...234,596,971
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 increases uptake ISO TRPV6 protein results in increased uptake of Barium CTD PMID:19996302, PMID:21146870 NCBI chr 4:70,918,631...70,934,291
Ensembl chr 4:70,918,632...70,934,295
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [barium chloride results in increased abundance of Barium] inhibits the reaction [Hydrocortisone results in increased expression of TSC22D3 mRNA] CTD PMID:29957541 NCBI chr  X:111,884,285...111,944,693
Ensembl chr  X:111,884,295...111,887,906
JBrowse link
G Urod uroporphyrinogen decarboxylase affects abundance ISO UROD protein affects the abundance of Barium CTD PMID:16325539 NCBI chr 5:135,855,429...135,859,515
Ensembl chr 5:135,855,433...135,859,643
JBrowse link
beryllium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Esr1 estrogen receptor 1 increases methylation EXP Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis EXP Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757, PMID:8629860 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Tnf tumor necrosis factor increases response to substance
increases secretion
increases expression
ISO TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
Beryllium results in increased expression of TNF mRNA
CTD PMID:8629860, PMID:12449171, PMID:15127972 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
beryllium dichloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 affects expression ISO beryllium chloride affects the expression of APEX1 mRNA CTD PMID:23793613 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase affects expression ISO beryllium chloride affects the expression of OGG1 mRNA CTD PMID:23793613 NCBI chr 4:145,282,828...145,289,367
Ensembl chr 4:145,282,797...145,289,326
JBrowse link
G Tp53 tumor protein p53 increases expression ISO beryllium chloride results in increased expression of TRP53 mRNA CTD PMID:23793613 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
beryllium difluoride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO beryllium fluoride promotes the reaction [ABCB1 protein mutant form binds to 8-azidoadenosine 5'-triphosphate] CTD PMID:11027628 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions EXP beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]; Cobalt promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Magnesium Chloride promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Manganese promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]]; Nickel promotes the reaction [beryllium fluoride promotes the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC6 protein]] CTD PMID:12069597 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 decreases activity ISO
EXP
beryllium fluoride results in decreased activity of ABCC8 protein CTD PMID:17561960, PMID:18025464 NCBI chr 1:102,110,708...102,191,287
Ensembl chr 1:102,110,708...102,191,287
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases expression ISO beryllium fluoride results in increased expression of CREB1 protein CTD PMID:11867686 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO beryllium fluoride results in increased expression of FOS protein CTD PMID:11867686 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases phosphorylation ISO beryllium fluoride results in increased phosphorylation of MAP2K1 protein CTD PMID:11867686 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO beryllium fluoride results in increased phosphorylation of MAPK3 protein CTD PMID:11867686 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO beryllium fluoride results in increased expression of MYC protein CTD PMID:11867686 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
beryllium dihydride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Esr1 estrogen receptor 1 increases methylation EXP Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis EXP Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757, PMID:8629860 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Tnf tumor necrosis factor increases expression
increases response to substance
increases secretion
ISO Beryllium results in increased expression of TNF mRNA
TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
CTD PMID:8629860, PMID:12449171, PMID:15127972 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
beryllium sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle increases expression ISO beryllium sulfate results in increased expression of ACTA2 mRNA CTD PMID:16314022 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Anxa5 annexin A5 increases expression ISO beryllium sulfate results in increased expression of ANXA5 mRNA CTD PMID:16314022 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases secretion
ISO beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter]
beryllium sulfate results in increased secretion of CCL3 mRNA
CTD PMID:16314022 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases secretion ISO beryllium sulfate results in increased secretion of CCL4 mRNA CTD PMID:16314022 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO beryllium sulfate results in increased expression of CCL5 mRNA CTD PMID:16314022 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression ISO beryllium sulfate results in increased expression of CD44 mRNA CTD PMID:16314022 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd86 CD86 molecule increases expression ISO beryllium sulfate results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of CDKN1A mRNA; beryllium sulfate results in increased expression of CDKN1A protein
CTD PMID:17395767 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO beryllium sulfate results in increased expression of CDKN2A mRNA; beryllium sulfate results in increased expression of CDKN2A protein CTD PMID:17395767 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein CTD PMID:10755711 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Ctsl cathepsin L increases expression ISO beryllium sulfate results in increased expression of CTSL mRNA CTD PMID:16314022 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases secretion ISO beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases secretion ISO beryllium sulfate results in increased secretion of CXCL1 mRNA CTD PMID:16314022 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Egr2 early growth response 2 increases expression ISO beryllium sulfate results in increased expression of EGR2 mRNA CTD PMID:16314022 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of FOS mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]
CTD PMID:11568973 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO beryllium sulfate results in increased expression of HNRNPA1 mRNA CTD PMID:16314022 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases secretion
increases expression
ISO 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased expression of ICAM1 mRNA]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]; Dimethyl Sulfoxide inhibits the reaction [beryllium sulfate results in increased secretion of ICAM1 protein]
beryllium sulfate results in increased expression of ICAM1 mRNA; beryllium sulfate results in increased expression of ICAM1 protein
CTD PMID:18539414 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of IFNG protein
[beryllium sulfate co-treated with IFNG protein] results in increased expression of CREB1 protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein; [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein; beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710, PMID:10755711, PMID:20974702 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il18 interleukin 18 increases expression ISO beryllium sulfate results in increased expression of IL18 mRNA; beryllium sulfate results in increased expression of IL18 protein CTD PMID:16100009 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il2 interleukin 2 increases expression ISO beryllium sulfate results in increased expression of IL2 mRNA CTD PMID:9328138 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il5 interleukin 5 increases expression ISO beryllium sulfate results in increased expression of IL5 mRNA CTD PMID:9328138 NCBI chr10:39,066,716...39,069,587
Ensembl chr10:39,066,716...39,069,587
JBrowse link
G Il6 interleukin 6 increases expression ISO beryllium sulfate results in increased expression of IL6 mRNA CTD PMID:9328138 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgb3 integrin subunit beta 3 increases expression ISO beryllium sulfate results in increased expression of ITGB3 mRNA CTD PMID:16314022 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUN protein; Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; Ro 31-8220 inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA] CTD PMID:10755711, PMID:11568973 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of JUNB protein CTD PMID:10755711 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G LOC100364500 RT1 class I, locus CE11-like increases expression ISO beryllium sulfate results in increased expression of HLA-A mRNA CTD PMID:16314022 NCBI chr20:2,704,153...2,707,111
Ensembl chr20:2,704,148...2,707,120
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP beryllium sulfate results in increased expression of MYC protein CTD PMID:2009323 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nedd8 NEDD8 ubiquitin like modifier increases expression ISO beryllium sulfate results in increased expression of NEDD8 mRNA CTD PMID:16314022 NCBI chr15:34,340,607...34,352,673
Ensembl chr15:34,340,607...34,352,673
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [beryllium sulfate co-treated with IFNG protein] results in increased expression of NFKB1 protein CTD PMID:10755711 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nova1 NOVA alternative splicing regulator 1 increases expression ISO beryllium sulfate results in increased expression of NOVA1 mRNA CTD PMID:16314022 NCBI chr 6:66,960,126...67,085,836
Ensembl chr 6:66,963,510...67,085,390
JBrowse link
G Rhoa ras homolog family member A increases expression ISO beryllium sulfate results in increased expression of RHOA mRNA CTD PMID:16314022 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Rpl22 ribosomal protein L22 increases expression ISO beryllium sulfate results in increased expression of RPL22 mRNA CTD PMID:16314022 NCBI chr 5:169,506,150...169,512,875
Ensembl chr 5:169,506,138...169,512,871
JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO beryllium sulfate results in increased expression of RPL30 mRNA CTD PMID:16314022 NCBI chr 7:73,213,538...73,216,431
Ensembl chr 7:73,213,581...73,216,251
JBrowse link
G Rpl37a ribosomal protein L37a increases expression ISO beryllium sulfate results in increased expression of RPL37A mRNA CTD PMID:16314022 NCBI chr 9:80,002,892...80,004,995 JBrowse link
G Rps7 ribosomal protein S7 increases expression ISO beryllium sulfate results in increased expression of RPS7 mRNA CTD PMID:16314022 NCBI chr 6:47,899,525...47,904,389
Ensembl chr 6:47,899,525...47,904,437
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 increases response to substance
increases expression
ISO HLA-DRB1 protein mutant form results in increased susceptibility to beryllium sulfate
beryllium sulfate results in increased expression of HLA-DRB1 mRNA
CTD PMID:16272364, PMID:16314022 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G Runx1 RUNX family transcription factor 1 multiple interactions ISO beryllium sulfate promotes the reaction [RUNX1 protein binds to CCL3 promoter] CTD PMID:16314022 NCBI chr11:32,765,147...33,003,061
Ensembl chr11:32,769,165...33,003,021
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO beryllium sulfate results in increased expression of SERPINB2 mRNA CTD PMID:16314022 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Sftpd surfactant protein D increases expression ISO beryllium sulfate results in increased expression of SFTPD mRNA CTD PMID:16314022 NCBI chr16:18,753,535...18,766,100
Ensembl chr16:18,745,458...18,766,174
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP beryllium sulfate inhibits the reaction [Hydrocortisone results in increased expression of TAT protein] CTD PMID:6120038 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tmsb4x thymosin beta 4, X-linked increases expression ISO beryllium sulfate results in increased expression of TMSB4X mRNA CTD PMID:16314022 NCBI chr  X:28,593,405...28,617,267
Ensembl chr  X:28,593,405...28,595,395
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO beryllium sulfate results in increased expression of TNF mRNA; beryllium sulfate results in increased expression of TNF protein
beryllium sulfate promotes the reaction [IFNG protein results in increased expression of TNF protein]
CTD PMID:10755710, PMID:10755711 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO beryllium sulfate promotes the reaction [TP53 protein binds to CDKN1A promoter]
beryllium sulfate results in increased expression of TP53 protein
CTD PMID:17395767, PMID:20974702 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Wnt4 Wnt family member 4 increases expression ISO beryllium sulfate results in increased expression of WNT4 mRNA CTD PMID:16314022 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
beryllium(0) term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Beryllium results in increased methylation of CDKN2A promoter] which results in decreased expression of CDKN2A mRNA CTD PMID:11872642 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Esr1 estrogen receptor 1 increases methylation EXP Beryllium results in increased methylation of ESR1 gene CTD PMID:11872642 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis EXP Beryllium results in increased mutagenesis of HRAS gene CTD PMID:7545909 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Beryllium results in increased expression of IL1B mRNA
Beryllium affects the expression of IL1B mRNA
CTD PMID:8473757, PMID:8629860 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Tnf tumor necrosis factor increases response to substance
increases secretion
increases expression
ISO TNF promoter polymorphism results in increased susceptibility to Beryllium
Beryllium results in increased secretion of TNF protein
Beryllium results in increased expression of TNF mRNA
CTD PMID:8629860, PMID:12449171, PMID:15127972 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
calcium atom term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions ISO Calcium deficiency inhibits the reaction [ABCB11 protein results in increased export of Taurocholic Acid] CTD PMID:25862123 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO Calcium deficiency inhibits the reaction [ABCB1 protein results in increased export of Xanthenes]; Calcium inhibits the reaction [Magnesium results in increased activity of ABCB1 protein] CTD PMID:2900677, PMID:25862123 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO Calcium deficiency inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:25862123 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Aco2 aconitase 2 increases activity
multiple interactions
ISO Calcium results in increased activity of ACO2 protein
[Calcium results in increased activity of ACO2 protein] which results in increased reduction of thiazolyl blue; [Nicardipine results in decreased uptake of Calcium] which results in decreased activity of ACO2 protein
CTD PMID:12548706 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Actb actin, beta multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of ACTB mRNA CTD PMID:15913539 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Adcy5 adenylate cyclase 5 decreases activity
increases response to substance
ISO Calcium results in decreased activity of ADCY5 protein
ADCY5 protein results in increased susceptibility to Calcium
CTD PMID:12065575, PMID:12869393 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Adcy9 adenylate cyclase 9 multiple interactions ISO Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]; Tacrolimus inhibits the reaction [Calcium inhibits the reaction [Miconazole results in increased activity of ADCY9 protein]] CTD PMID:30607468 NCBI chr10:11,392,698...11,515,406
Ensembl chr10:11,392,625...11,512,600
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases abundance
affects abundance
multiple interactions
EXP ADCYAP1 protein results in increased abundance of Calcium
ADCYAP1 protein affects the abundance of Calcium
Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium]
CTD PMID:18198219, PMID:21039959 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 multiple interactions EXP [alpha-latrotoxin binds to ADGRL1 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL1 protein] which results in increased uptake of Calcium CTD PMID:10026162 NCBI chr19:25,029,037...25,069,146
Ensembl chr19:25,029,037...25,069,142
JBrowse link
G Adgrl2 adhesion G protein-coupled receptor L2 multiple interactions EXP [alpha-latrotoxin binds to ADGRL2 protein] which results in increased uptake of Calcium; [black widow spider venom binds to ADGRL2 protein] which results in increased uptake of Calcium CTD PMID:10026162 NCBI chr 2:258,792,838...258,997,145
Ensembl chr 2:258,792,839...258,997,145
JBrowse link
G Adm adrenomedullin decreases expression ISO Calcium results in decreased expression of ADM mRNA CTD PMID:20682585 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions
affects transport
EXP
ISO
[Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; [Phenylephrine binds to and results in increased activity of ADRA1A protein] which results in increased transport of Calcium; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein]; Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]
5-methylurapidil inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; [A 61603 results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased abundance of Calcium]
ADRA1A protein affects the transport of Calcium
CTD PMID:12935885, PMID:15306222, PMID:15639650, PMID:15672411, PMID:16498073, PMID:20030735 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra1b adrenoceptor alpha 1B multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1B protein] which results in increased abundance of Calcium] CTD PMID:15306222, PMID:16498073, PMID:20030735 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Adra1d adrenoceptor alpha 1D multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; [Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium; carvedilol inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; carvedilol inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Epinephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium]; Phentolamine inhibits the reaction [[Phenylephrine results in increased activity of ADRA1D protein] which results in increased abundance of Calcium] CTD PMID:15306222, PMID:20030735 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566
JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2A protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr 1:274,766,283...274,769,083
Ensembl chr 1:274,766,283...274,769,081
JBrowse link
G Adra2b adrenoceptor alpha 2B multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [Oxymetazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium; [xylometazoline binds to and results in increased activity of ADRA2B protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr 3:119,805,941...119,809,987
Ensembl chr 3:119,805,941...119,809,987
JBrowse link
G Adra2c adrenoceptor alpha 2C multiple interactions ISO [Epinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium; [Norepinephrine binds to and results in increased activity of ADRA2C protein] which results in increased abundance of Calcium CTD PMID:20030735 NCBI chr14:80,730,307...80,732,010
Ensembl chr14:80,730,307...80,732,010
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions EXP
ISO
[Terbutaline binds to and results in increased activity of ADRB2 protein] which affects the abundance of Calcium
[Benzo(a)pyrene binds to ADRB2 protein] which results in increased transport of Calcium; ADRB2 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium]
CTD PMID:10372813, PMID:22167199 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Ago2 argonaute RISC catalytic component 2 multiple interactions EXP Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]] CTD PMID:28404816 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Agt angiotensinogen increases uptake
affects localization
multiple interactions
increases abundance
ISO
EXP
AGT protein results in increased uptake of Calcium
AGT protein affects the localization of Calcium
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [AGT protein affects the localization of Calcium]; bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium]; Heparin inhibits the reaction [AGT protein affects the localization of Calcium]; Losartan inhibits the reaction [AGT protein affects the localization of Calcium]; Saralasin inhibits the reaction [AGT protein affects the localization of Calcium]; Sirolimus inhibits the reaction [AGT protein affects the localization of Calcium]; xestospongin C inhibits the reaction [AGT protein affects the localization of Calcium]
[AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species
Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]
benidipine inhibits the reaction [AGT protein results in increased uptake of Calcium]; Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium]
CTD PMID:10660688, PMID:18331727, PMID:18854758, PMID:21613610 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Calcium affects the expression of AGTR1A mRNA CTD PMID:15913539 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr1b angiotensin II receptor, type 1b multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of AGTR1B mRNA CTD PMID:15913539 NCBI chr 2:105,149,020...105,224,335
Ensembl chr 2:105,149,020...105,224,295
JBrowse link
G Akap1 A-kinase anchoring protein 1 affects expression EXP Calcium affects the expression of AKAP1 mRNA CTD PMID:15913539 NCBI chr10:76,151,013...76,183,987
Ensembl chr10:76,151,038...76,166,276
JBrowse link
G Akap11 A-kinase anchoring protein 11 affects expression EXP Calcium affects the expression of AKAP11 mRNA CTD PMID:15913539 NCBI chr15:60,722,138...60,766,673
Ensembl chr15:60,722,160...60,766,579
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects abundance
affects expression
multiple interactions
affects response to substance
ISO
EXP
AKT1 protein affects the abundance of Calcium
Calcium affects the expression of AKT1 mRNA
[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; PX-866 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; STO 609 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]; W 7 inhibits the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]
AKT1 protein affects the susceptibility to Calcium
CTD PMID:15913539, PMID:16094411, PMID:16236484, PMID:28634229 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO ALDH2 protein inhibits the reaction [Ethanol affects the abundance of Calcium]
Calcium affects the reaction [ALDH2 gene SNP affects the abundance of Lead]
CTD PMID:17590987, PMID:28212632 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase affects binding ISO Calcium binds to ALG2 protein CTD PMID:18997320 NCBI chr 5:63,187,466...63,192,025
Ensembl chr 5:63,187,468...63,192,025
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions ISO Calcium promotes the reaction [L 708714 binds to ALOX5 protein] CTD PMID:7577949 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Alpp alkaline phosphatase, placental affects binding ISO Calcium binds to ALPP protein CTD PMID:16815919 NCBI chr 9:94,189,961...94,193,054
Ensembl chr 9:94,190,067...94,192,813
JBrowse link
G Anxa1 annexin A1 affects activity EXP Calcium affects the activity of ANXA1 protein CTD PMID:20655937 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa5 annexin A5 multiple interactions ISO Calcium binds to and results in increased activity of ANXA5 protein; Calcium promotes the reaction [Phosphatidylserines binds to ANXA5 protein] CTD PMID:11578147, PMID:16076491 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Aoc1 amine oxidase, copper containing 1 affects binding ISO AOC1 protein binds to Calcium CTD PMID:12072962 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
G Apoe apolipoprotein E affects abundance
affects expression
ISO
EXP
APOE protein affects the abundance of Calcium
Calcium affects the expression of APOE mRNA
CTD PMID:15913539, PMID:17899169 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apom apolipoprotein M affects expression EXP Calcium affects the expression of APOM mRNA CTD PMID:15913539 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases uptake
affects abundance
ISO
EXP
2,4-Dinitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 3-nitrophenol affects the reaction [APP protein affects the abundance of Calcium]; 4-anisidine affects the reaction [APP protein affects the abundance of Calcium]
APP protein modified form results in increased uptake of Calcium; APP protein results in increased uptake of Calcium
Calcium deficiency inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; Flurbiprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Ibuprofen inhibits the reaction [APP protein results in increased uptake of Calcium]; Indomethacin inhibits the reaction [APP protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [APP protein results in increased uptake of Calcium]; Ruthenium Red inhibits the reaction [APP protein modified form results in increased uptake of Calcium]; Salicylates inhibits the reaction [APP protein results in increased uptake of Calcium]; sulindac sulfide inhibits the reaction [APP protein results in increased uptake of Calcium]
CTD PMID:12383957, PMID:18648507, PMID:18949129, PMID:24457011 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO
EXP
ARRB2 protein affects the abundance of and affects the localization of Calcium
ARRB2 promotes the reaction [carvedilol results in increased uptake of Calcium]
CTD PMID:16210646, PMID:21078978 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of ATP1A1 mRNA CTD PMID:15913539 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions EXP Calcium affects the reaction [Ouabain results in increased expression of ATP1B1 mRNA] CTD PMID:11204457 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 affects transport
multiple interactions
EXP
ISO
ATP2A1 protein affects the transport of Calcium
[Phenols results in decreased activity of ATP2A1 protein] which results in decreased transport of Calcium
CTD PMID:11230109, PMID:18773882 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 affects abundance
affects transport
multiple interactions
affects uptake
affects export
ISO
EXP
ATP2A2 protein affects the abundance of Calcium
ATP2A2 protein affects the transport of Calcium
[[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in decreased expression of ATP2A2 protein] which results in decreased transport of Calcium; [Thapsigargin results in decreased activity of ATP2A2 protein] which results in decreased transport of Calcium
PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]
ATP2A2 protein alternative form affects the uptake of Calcium
ATP2A2 protein alternative form affects the export of Calcium
CTD PMID:11679415, PMID:16236312, PMID:17287366, PMID:19244478, PMID:19328205, PMID:19700627 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions
increases export
ISO caloxin 1b1 inhibits the reaction [ATP2B1 protein results in increased export of Calcium] CTD PMID:16452157 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases export
multiple interactions
ISO ATP2B4 protein results in increased export of Calcium
caloxin 1b1 inhibits the reaction [ATP2B4 protein results in increased export of Calcium]
CTD PMID:16452157 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 multiple interactions EXP Calcium inhibits the reaction [ATP8B1 protein results in increased transport of Phosphatidylserines] CTD PMID:11584374 NCBI chr18:60,013,388...60,152,920
Ensembl chr18:60,013,382...60,095,354
JBrowse link
G Avp arginine vasopressin multiple interactions
increases uptake
increases abundance
EXP 1-Butanol inhibits the reaction [AVP protein results in increased abundance of Calcium]; 2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid inhibits the reaction [AVP protein results in increased abundance of Calcium]; [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium; AVP protein results in increased import of and results in increased abundance of Calcium; Carvedilol inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; Chromium affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; chromium tripicolinate affects the reaction [INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]; INS1 protein affects the reaction [Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; INS1 protein affects the reaction [chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium]]; Nicardipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium]; Nifedipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] CTD PMID:9446840, PMID:11356622, PMID:11553362, PMID:14711191, PMID:21039959 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions EXP [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein; [AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; [NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium; Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]; Nicardipine inhibits the reaction [Carbachol promotes the reaction [[NC 1900 results in increased activity of AVPR1A protein] which results in increased abundance of Calcium]] CTD PMID:11553362, PMID:12646291 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Avpr2 arginine vasopressin receptor 2 affects expression EXP Calcium affects the expression of AVPR2 mRNA CTD PMID:15913539 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213
JBrowse link
G Axin1 axin 1 affects expression EXP Calcium affects the expression of AXIN1 mRNA CTD PMID:15913539
G Bad BCL2-associated agonist of cell death affects expression EXP Calcium affects the expression of BAD mRNA CTD PMID:15913539 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions ISO
EXP
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; [kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; Sodium affects the reaction [[kallidin, des-Arg(10)- results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]
[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium; bradykinin, Lys-Leu(8)-desArg(9)- inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]; Indomethacin inhibits the reaction [[kallidin, des-Arg(10)- binds to and results in increased activity of BDKRB1 protein] which results in increased abundance of Calcium]
CTD PMID:15703175, PMID:22554775 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions ISO BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium]
BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]
CTD PMID:16473424, PMID:18054572 NCBI chr 6:129,399,468...129,429,676
Ensembl chr 6:129,399,468...129,429,676
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases transport
ISO [Cadmium results in decreased transport of Calcium] inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]; Calcium affects the reaction [Oxygen deficiency results in increased secretion of BDNF protein]
BDNF protein results in increased transport of Calcium
3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]; 3,5-dichloro-N-(1-(2,2-dimethyltetrahydropyran-4-ylmethyl)-4-fluoropiperidin-4-ylmethyl)benzamide promotes the reaction [Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]]; Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]; Tetrodotoxin inhibits the reaction [Oxygen deficiency promotes the reaction [BDNF protein results in increased transport of Calcium]]
CTD PMID:16553631, PMID:26095976 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Best1 bestrophin 1 increases activity
multiple interactions
ISO Calcium results in increased activity of BEST1 protein
[PAR-1-activating peptide results in increased abundance of Calcium] which results in increased activity of BEST1 protein
CTD PMID:19828819 NCBI chr 1:226,033,146...226,049,893
Ensembl chr 1:226,030,875...226,049,929
JBrowse link
G Bmp4 bone morphogenetic protein 4 affects expression
multiple interactions
EXP
ISO
Calcium affects the expression of BMP4 mRNA
[Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]
CTD PMID:15913539, PMID:18369157 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Btk Bruton tyrosine kinase affects transport ISO BTK protein affects the transport of Calcium CTD PMID:12848851 NCBI chr  X:105,360,922...105,390,580
Ensembl chr  X:105,360,922...105,390,580
JBrowse link
G C5 complement C5 multiple interactions ISO [C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium; resveratrol inhibits the reaction [[C5 protein results in increased activity of and results in increased localization of SPHK1 protein] which results in increased abundance of Calcium] CTD PMID:19284563, PMID:19346296 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Ca4 carbonic anhydrase 4 affects expression EXP Calcium affects the expression of CA4 mRNA CTD PMID:15913539 NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A increases transport
multiple interactions
EXP CACNA1A protein results in increased transport of Calcium
Allethrins inhibits the reaction [CACNA1A protein results in increased transport of Calcium]
CTD PMID:14634047 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1b calcium voltage-gated channel subunit alpha1 B multiple interactions
decreases uptake
increases transport
EXP decamethrin inhibits the reaction [CACNA1B protein results in increased transport of Calcium]; decamethrin promotes the reaction [CACNA1B gene mutant form results in increased transport of Calcium]
CACNA1B protein alternative form results in decreased uptake of Calcium
CTD PMID:18383452, PMID:22891239 NCBI chr 3:1,740,026...1,924,959
Ensembl chr 3:1,740,024...1,924,827
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases transport
multiple interactions
ISO
EXP
CACNA1C protein results in increased transport of Calcium
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium]
Allethrins inhibits the reaction [CACNA1C protein results in increased transport of Calcium]
CTD PMID:12181424, PMID:14634047, PMID:15299022 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D affects transport
multiple interactions
ISO
EXP
CACNA1D protein affects the transport of Calcium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]
[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium]
CTD PMID:15357422, PMID:17272349, PMID:19796812, PMID:27798183 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E increases transport
multiple interactions
ISO
EXP
CACNA1E protein results in increased transport of Calcium
Calcium inhibits the reaction [Methacholine Chloride affects the reaction [CACNA1E protein results in increased transport of Barium]]
Cadmium inhibits the reaction [CACNA1E protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1E protein results in increased transport of Calcium]
CTD PMID:10627594, PMID:10669483, PMID:12663092 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980
JBrowse link
G Cacna1f calcium voltage-gated channel subunit alpha1 F increases transport ISO CACNA1F protein results in increased transport of Calcium CTD PMID:14744918 NCBI chr  X:15,712,709...15,741,135
Ensembl chr  X:15,712,713...15,741,103
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G increases transport
multiple interactions
ISO
EXP
CACNA1G protein results in increased transport of Calcium
Allethrins inhibits the reaction [CACNA1G protein results in increased transport of Calcium]
CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]; CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium]
CTD PMID:10734232, PMID:11073957, PMID:14634047 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases transport
multiple interactions
ISO
EXP
CACNA1H protein results in increased transport of Calcium
Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium]
Amiloride inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Mibefradil inhibits the reaction [CACNA1H protein results in increased transport of Calcium]; Nickel inhibits the reaction [CACNA1H protein results in increased transport of Calcium]
CTD PMID:9930755, PMID:11073957, PMID:11897840 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I increases transport EXP CACNA1I protein results in increased transport of Calcium CTD PMID:11073957 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 multiple interactions
increases transport
ISO
EXP
[gabapentin results in decreased activity of CACNA2D1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]; CACNA2D1 protein affects the reaction [Potassium Chloride results in increased transport of Calcium]
CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]
CACNA2D1 protein results in increased transport of Calcium
CTD PMID:15474003, PMID:17442347, PMID:17881535, PMID:19796812 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 affects transport
multiple interactions
ISO CACNA2D2 protein affects the transport of Calcium
CACNA2D2 gene mutant form inhibits the reaction [CACNA1D protein results in increased import of Calcium]
CTD PMID:14660671, PMID:27798183 NCBI chr 8:116,154,661...116,285,643
Ensembl chr 8:116,154,736...116,284,985
JBrowse link
G Cacna2d4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 multiple interactions ISO [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium] CTD PMID:12181424 NCBI chr 4:151,298,548...151,409,263
Ensembl chr 4:151,298,548...151,409,263
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 multiple interactions ISO
EXP
[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium; [CACNA2D4 protein binds to CACNA1C protein binds to CACNB3 protein] which results in increased transport of Calcium; CACNA2D4 protein promotes the reaction [[CACNA1C protein co-treated with CACNB3 protein] results in increased transport of Calcium]
[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium; CACNA2D1 protein promotes the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]; gabapentin affects the reaction [[CACNA1D protein co-treated with CACNB3 protein] results in increased transport of Calcium]
CTD PMID:12181424, PMID:19796812 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 multiple interactions ISO CACNG2 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr 7:119,228,112...119,353,332
Ensembl chr 7:119,228,102...119,352,605
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 multiple interactions ISO CACNG4 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr10:95,954,160...96,015,484
Ensembl chr10:95,951,234...96,015,499
JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 multiple interactions ISO CACNG5 protein affects the reaction [CACNA1G protein results in increased transport of Calcium] CTD PMID:10734232 NCBI chr10:96,122,240...96,166,606
Ensembl chr10:96,123,397...96,131,880
JBrowse link
G Calb1 calbindin 1 affects expression EXP Calcium affects the expression of CALB1 mRNA CTD PMID:15913539 NCBI chr 5:29,538,380...29,562,774
Ensembl chr 5:29,538,380...29,562,773
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases expression
ISO
EXP
rimabotulinumtoxinB inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; rimabotulinumtoxinB inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]
Calcium promotes the reaction [Lipopolysaccharides results in increased expression of CALCA mRNA]
Calcium results in increased expression of CALCA mRNA
Calcium results in increased expression of CALCA protein
[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein; [KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; [Potassium co-treated with Calcium] results in increased secretion of CALCA protein; [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; botulinum toxin type D inhibits the reaction [[Capsaicin co-treated with Calcium] results in increased secretion of CALCA protein]; botulinum toxin type D inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Botulinum Toxins, Type A inhibits the reaction [[Potassium co-treated with Calcium] results in increased secretion of CALCA protein]; Calcium affects the reaction [Capsaicin inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium affects the reaction [Capsaicin inhibits the reaction [mustard oil results in increased secretion of CALCA protein]]; Calcium affects the reaction [mustard oil inhibits the reaction [Capsaicin results in increased secretion of CALCA protein]]; Calcium deficiency inhibits the reaction [safranal results in increased secretion of CALCA protein]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]
CTD PMID:2470235, PMID:12574409, PMID:17590514, PMID:17666428, PMID:20682585, PMID:30636360 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calm1 calmodulin 1 multiple interactions
affects binding
EXP
ISO
[Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]; Calcium binds to and affects the folding of CALM1 protein
Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]
CTD PMID:15381065, PMID:15628869, PMID:17098364 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calr calreticulin affects response to substance
multiple interactions
ISO CALR protein affects the susceptibility to Calcium
CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]
CTD PMID:7961812 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta affects expression EXP Calcium affects the expression of CAMK2D mRNA CTD PMID:15913539 NCBI chr 2:230,900,907...231,132,207
Ensembl chr 2:230,901,126...231,132,039
JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 multiple interactions ISO CAMKK2 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein] CTD PMID:28634229 NCBI chr12:39,253,409...39,302,601
Ensembl chr12:39,253,409...39,302,601
JBrowse link
G Capn1 calpain 1 multiple interactions
increases activity
ISO
EXP
[Caffeine co-treated with Alprazolam] promotes the reaction [Calcium results in increased activity of CAPN1 protein]; [Calcium co-treated with CAPN1 protein] results in increased degradation of TP73 protein modified form
calpain inhibitor III inhibits the reaction [Calcium results in increased activity of CAPN1 protein]
CTD PMID:19490937, PMID:21516125, PMID:21985864 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP3 mRNA]
Calcium deficiency inhibits the reaction [Dasatinib results in increased activity of CASP3 protein]; Calcium deficiency inhibits the reaction [Ionomycin results in increased activity of CASP3 protein]
CTD PMID:24184500, PMID:29803841 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions EXP [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA]]; Calcium affects the reaction [sodium arsenite results in increased expression of CASP9 mRNA] CTD PMID:24184500 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Casr calcium-sensing receptor increases phosphorylation
multiple interactions
increases uptake
increases activity
affects expression
decreases response to substance
increases response to substance
ISO
EXP
Calcium results in increased phosphorylation of CASR protein
[Aluminum binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Calcium binds to and results in increased activity of CASR protein] which results in increased abundance of Inositol Phosphates; [Gadolinium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Magnesium binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; [Neomycin binds to and results in increased activity of CASR protein] which results in increased abundance of Calcium; Calcium binds to and results in increased activity of CASR protein; Gadolinium inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]
CASR protein results in increased uptake of Calcium
Calcium results in increased activity of CASR protein
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [CASR protein results in increased uptake of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [CASR protein results in increased uptake of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; 2-aminoethoxydiphenyl borate inhibits the reaction [CASR protein results in increased uptake of Calcium]; [2-quinoxaline-carboxamide-N-adamantan-1-yl binds to and results in decreased activity of CASR protein] inhibits the reaction [Nickel results in increased abundance of Calcium]; [Calcium binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; [CASR protein mutant form results in increased susceptibility to Calcium] which results in increased abundance of Inositol 1,4,5-Trisphosphate; [Spermine binds to and results in increased activity of CASR protein] which results in increased uptake of Calcium; bisindolylmaleimide I inhibits the reaction [NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]]; Calcium Chloride promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of WNT5A protein]; CASR protein affects the reaction [Nickel results in increased abundance of Calcium]; CASR protein promotes the reaction [TRPC6 protein results in increased uptake of Calcium]; chelerythrine inhibits the reaction [CASR protein results in increased uptake of Calcium]; Flufenamic Acid promotes the reaction [CASR protein results in increased uptake of Calcium]; Lanthanum inhibits the reaction [Calcium binds to and results in increased activity of CASR protein]; Lanthanum inhibits the reaction [CASR protein results in increased uptake of Calcium]; methyl-beta-cyclodextrin inhibits the reaction [CASR protein results in increased uptake of Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine affects the reaction [CASR gene mutant form results in increased susceptibility to Calcium]; N-(2-chlorophenylpropyl)-1-(3-methoxyphenyl)ethylamine promotes the reaction [CASR protein results in increased susceptibility to Calcium]; NPS R-467 promotes the reaction [Calcium results in increased phosphorylation of CASR protein]; Pertussis Toxin inhibits the reaction [CASR protein results in increased uptake of Calcium]
Calcium affects the expression of CASR mRNA; Calcium affects the expression of CASR protein
CASR protein mutant form results in decreased susceptibility to Calcium
CASR gene mutant form results in increased susceptibility to Calcium; CASR protein mutant form results in increased susceptibility to Calcium
CTD PMID:7874174, PMID:9011580, PMID:10231437, PMID:11071898, PMID:11089548, PMID:11701698, PMID:15788476, PMID:17041782, PMID:17376781, PMID:19781536, PMID:21562303, PMID:24658506 NCBI chr11:67,188,204...67,262,261
Ensembl chr11:67,188,630...67,258,771
JBrowse link
G Cat catalase multiple interactions ISO
EXP
CAT protein inhibits the reaction [Gadolinium promotes the reaction [TRPC5 protein results in increased transport of Calcium]]; CAT protein inhibits the reaction [Hydrogen Peroxide promotes the reaction [TRPC5 protein results in increased transport of Calcium]]
[Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of CAT protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of CAT protein]; [Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CAT protein]; Calcium affects the reaction [sodium arsenite results in decreased activity of CAT protein]
CTD PMID:21127073, PMID:22534743, PMID:24184500 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 affects transport ISO CAV1 protein affects the transport of Calcium CTD PMID:16428350 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cav3 caveolin 3 multiple interactions ISO CAV3 protein affects the reaction [Potassium Chloride results in increased uptake of Calcium] CTD PMID:21294223 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Cbfb core-binding factor subunit beta affects expression EXP Calcium affects the expression of CBFB mRNA CTD PMID:15913539 NCBI chr19:37,127,508...37,171,075
Ensembl chr19:37,127,508...37,171,069
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases uptake ISO CCL11 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases uptake ISO CCL13 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases abundance
multiple interactions
increases uptake
ISO CCL2 protein results in increased abundance of Calcium
montelukast inhibits the reaction [CCL2 protein results in increased abundance of Calcium]; Piperidines analog inhibits the reaction [CCL2 protein results in increased uptake of Calcium]; resveratrol inhibits the reaction [CCL2 protein affects the localization of Calcium]
CTD PMID:10843593, PMID:10984371, PMID:16212921, PMID:16771778 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO resveratrol inhibits the reaction [CCL3 protein affects the localization of Calcium] CTD PMID:16212921 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases uptake ISO CCL5 protein results in increased uptake of Calcium CTD PMID:10984371 NCBI chr10:70,739,764...70,744,303
Ensembl chr10:70,739,800...70,744,315
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases uptake
multiple interactions
ISO CCL7 protein results in increased uptake of Calcium
Piperidines analog inhibits the reaction [CCL7 protein results in increased uptake of Calcium]
CTD PMID:10843593, PMID:10984371 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccnd1 cyclin D1 affects expression
increases expression
EXP
ISO
Calcium affects the expression of CCND1 mRNA
Calcium results in increased expression of CCND1 mRNA
CTD PMID:15913539, PMID:24658506 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccr10 C-C motif chemokine receptor 10 affects abundance ISO CCR10 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr10:89,086,556...89,088,993
Ensembl chr10:89,086,556...89,088,993
JBrowse link
G Ccr4 C-C motif chemokine receptor 4 affects abundance ISO CCR4 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:122,530,152...122,535,959
Ensembl chr 8:122,530,624...122,532,070
JBrowse link
G Ccr8 C-C motif chemokine receptor 8 affects abundance ISO CCR8 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:128,779,552...128,782,531
Ensembl chr 8:128,781,395...128,782,456
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 affects abundance ISO CCR9 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:132,827,325...132,842,130
Ensembl chr 8:132,828,091...132,842,130
JBrowse link
G Cd28 Cd28 molecule multiple interactions
increases abundance
ISO 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 2-aminoethoxydiphenylborane inhibits the reaction [CD28 protein results in increased abundance of Calcium]; 5-diisopropoxyphosphoryl-5-methyl-1-pyrroline-N-oxide inhibits the reaction [CD28 protein results in increased abundance of Calcium]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [CD28 protein results in increased abundance of Calcium] CTD PMID:14607919 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cd38 CD38 molecule multiple interactions ISO CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]] CTD PMID:20200208 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cdc42 cell division cycle 42 multiple interactions ISO Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] CTD PMID:16369480 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdc42bpb CDC42 binding protein kinase beta affects expression EXP Calcium affects the expression of CDC42BPB mRNA CTD PMID:15913539 NCBI chr 6:135,746,743...135,830,144
Ensembl chr 6:135,746,754...135,830,086
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases cleavage
multiple interactions
ISO Calcium results in increased cleavage of CDK5R1 protein
calpeptin inhibits the reaction [Calcium results in increased cleavage of CDK5R1 protein]
CTD PMID:18242949 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta affects expression EXP Calcium affects the expression of CEBPB mRNA CTD PMID:15913539 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cerk ceramide kinase multiple interactions ISO Calcium affects the reaction [CERK protein results in increased phosphorylation of Ceramides] CTD PMID:16269826 NCBI chr 7:127,015,162...127,058,056
Ensembl chr 7:127,015,162...127,058,056
JBrowse link
G Cfb complement factor B multiple interactions ISO CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cfd complement factor D multiple interactions ISO CFD protein affects the reaction [[cobra venom factor co-treated with Magnesium co-treated with Calcium] results in increased cleavage of CFB protein] CTD PMID:11724962 NCBI chr 7:12,634,216...12,635,939
Ensembl chr 7:12,634,216...12,635,943
JBrowse link
G Cfl1 cofilin 1 multiple interactions ISO [Capsaicin results in decreased phosphorylation of and results in increased activity of CFL1 protein] which results in increased import of Calcium CTD PMID:17303079 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO
EXP
[Acetylcholine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; [Pilocarpine results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; CHRM1 protein promotes the reaction [Methacholine Compounds results in increased abundance of Calcium]
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 1-oleoyl-2-acetylglycerol promotes the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; [Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium; Atropine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Flufenamic Acid inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Gadolinium inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Lanthanum inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Pirenzepine inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]; Thapsigargin inhibits the reaction [[Carbachol results in increased activity of CHRM1 protein] which results in increased abundance of Calcium]
[[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine; [[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein
CTD PMID:11527950, PMID:11553362, PMID:12456425, PMID:18316702 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP [CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine] CTD PMID:12754307 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit multiple interactions ISO
EXP
[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium; [[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] which results in increased uptake of Calcium] inhibits the reaction [CHRNA7 protein results in decreased susceptibility to Okadaic Acid]; [Acetylcholine results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; [Bungarotoxins binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [methyllycaconitine binds to and results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium; [PNU-282987 binds to and results in increased activity of CHRNA7 protein] which results in increased uptake of Calcium; Bungarotoxins inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; Mecamylamine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine inhibits the reaction [[[1-(5-chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea affects the activity of CHRNA7 protein] co-treated with [PNU-282987 binds to and results in increased activity of CHRNA7 protein]] results in increased uptake of Calcium]; methyllycaconitine promotes the reaction [[Nicotine results in increased activity of CHRNA7 protein] which results in increased transport of Calcium] CTD PMID:17709503, PMID:21051662, PMID:21715663 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO
EXP
[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium; alpha-conotoxin MII inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Calcium affects the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased susceptibility to Okadaic Acid]; Dihydro-beta-Erythroidine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]; Mecamylamine inhibits the reaction [[5-iodo-3-(2-azetidinylmethoxy)pyridine binds to and results in increased activity of CHRNB2 protein] which results in decreased uptake of Calcium]
[CHRNA4 protein co-treated with CHRNB2 protein mutant form] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein co-treated with CHRNB2 protein] affects the reaction [Calcium results in increased susceptibility to Acetylcholine]; [CHRNA4 protein mutant form co-treated with CHRNB2 protein] inhibits the reaction [Calcium results in increased susceptibility to Acetylcholine]
CTD PMID:12754307, PMID:21715663 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 affects expression EXP Calcium affects the expression of CITED2 mRNA CTD PMID:15913539 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cnnm4 cyclin and CBS domain divalent metal cation transport mediator 4 affects expression EXP Calcium affects the expression of CNNM4 mRNA CTD PMID:15913539 NCBI chr 9:43,049,587...43,088,690
Ensembl chr 9:43,049,587...43,088,702
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]; [Win 55212-2 binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 mRNA]; Calcium affects the reaction [Potassium Chloride results in decreased expression of CNR1 protein]; CNR1 protein affects the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; CNR1 protein affects the reaction [Win 55212-2 inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Pertussis Toxin inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium results in increased transport of Calcium]]; rimonabant inhibits the reaction [[3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; rimonabant inhibits the reaction [[Win 55212-2 binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]] CTD PMID:12421626, PMID:14973253, PMID:16412482 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]] CTD PMID:10617657 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain affects abundance ISO COL18A1 protein affects the abundance of Calcium CTD PMID:15296943 NCBI chr20:12,225,202...12,332,858
Ensembl chr20:12,225,202...12,332,858
JBrowse link
G Col1a2 collagen type I alpha 2 chain affects abundance ISO COL1A2 protein affects the abundance of Calcium CTD PMID:10913914 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Cp ceruloplasmin affects binding
multiple interactions
ISO
EXP
Calcium binds to CP protein
[Zinc co-treated with Iron co-treated with Calcium] inhibits the reaction [lead acetate results in decreased expression of CP protein]
CTD PMID:17242517, PMID:22534743 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression
multiple interactions
EXP Calcium affects the expression of CREB1 mRNA
[Estradiol results in increased import of Calcium] which results in increased activity of CREB1 protein; Calcium promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased phosphorylation of CREB1 protein]; Calcium promotes the reaction [Dopamine results in increased phosphorylation of CREB1 protein]
CTD PMID:14622123, PMID:15802184, PMID:15913539 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 affects expression EXP Calcium affects the expression of CSNK1A1 mRNA CTD PMID:15913539 NCBI chr18:56,887,722...56,910,610
Ensembl chr18:56,887,354...56,918,345
JBrowse link
G Csnk1g3 casein kinase 1, gamma 3 affects expression EXP Calcium affects the expression of CSNK1G3 mRNA CTD PMID:15913539 NCBI chr18:48,831,209...48,913,341
Ensembl chr18:48,853,418...48,911,122
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions
ISO Calcium results in increased expression of CTNNB1 mRNA; Calcium results in increased expression of CTNNB1 protein
CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]
CTD PMID:24658506 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctss cathepsin S multiple interactions ISO [CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CTSS protein results in increased cleavage of and results in increased activity of CXCL5 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases abundance
multiple interactions
EXP CXCL1 protein results in increased abundance of Calcium
epigallocatechin gallate inhibits the reaction [CXCL1 protein results in increased abundance of Calcium]
CTD PMID:9430702, PMID:15237969 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [CTSS protein results in increased cleavage of and results in decreased activity of CXCL10 protein] which results in decreased uptake of Calcium; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions
increases uptake
ISO resveratrol inhibits the reaction [CXCL12 protein affects the localization of Calcium]
CXCL12 protein results in increased uptake of Calcium
CTD PMID:10984371, PMID:11872090, PMID:16212921 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [CTSS protein results in increased cleavage of and results in increased activity of CXCL2 protein] which results in increased uptake of Calcium; [CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium CTD PMID:25833952 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions
increases abundance
ISO [[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CTSS protein results in increased cleavage of and results in decreased activity of CXCL9 protein] which results in decreased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium
CXCL9 protein results in increased abundance of Calcium
CTD PMID:12517959, PMID:25833952 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 multiple interactions
affects abundance
ISO [CXCL8 protein binds to and results in increased activity of CXCR1 protein] which results in increased abundance of and results in increased activity of Calcium
CXCR1 protein affects the abundance of Calcium
CTD PMID:11298490, PMID:12055238 NCBI chr 9:81,466,430...81,469,299
Ensembl chr 9:81,466,332...81,469,274
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 affects transport
multiple interactions
ISO CXCR2 protein affects the transport of Calcium
[CXCL2 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL5 protein modified form binds to and results in increased activity of CXCR2 protein] which results in increased uptake of Calcium; [CXCL8 protein binds to and results in increased activity of CXCR2 protein] which results in increased abundance of and results in increased activity of Calcium
Excitatory Amino Acid Agonists inhibits the reaction [CXCR2 protein affects the localization of Calcium]
CTD PMID:11298490, PMID:15618463, PMID:15914698, PMID:25833952 NCBI chr 9:81,427,275...81,435,065
Ensembl chr 9:81,427,730...81,434,102
JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 affects abundance
multiple interactions
ISO CXCR3 protein affects the abundance of Calcium
[[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [CXCL10 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium; [CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased uptake of Calcium
CTD PMID:12055238, PMID:12517959, PMID:25833952 NCBI chr  X:71,614,346...71,616,997
Ensembl chr  X:71,614,346...71,616,997
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 affects abundance ISO CXCR4 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 affects abundance ISO CXCR5 protein affects the abundance of Calcium CTD PMID:12055238 NCBI chr 8:48,835,688...48,852,032
Ensembl chr 8:48,836,957...48,850,671
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases secretion
decreases secretion
EXP [Calcium co-treated with Phosphates] affects the localization of CYCS protein; caffeic acid phenethyl ester inhibits the reaction [Calcium results in increased secretion of CYCS protein]; Cyclosporine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; Nicotine inhibits the reaction [[Calcium co-treated with Phosphates] affects the localization of CYCS protein]; xestospongin C inhibits the reaction [Calcium results in decreased secretion of CYCS protein] CTD PMID:15345483, PMID:15469948, PMID:15985439 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP
2-aminoethoxydiphenyl borate inhibits the reaction [[oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA]; [2,3,7,8-tetrachlorodibenzofuran co-treated with Calcium] results in increased expression of CYP1A1 mRNA; [oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA; Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
CTD PMID:1979076, PMID:11959854, PMID:16237193, PMID:23298284 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO Calcium promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]; Calcium promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]
CTD PMID:16237193, PMID:19782052 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 affects expression
multiple interactions
EXP Calcium affects the expression of CYP24A1 mRNA
[Calcium co-treated with Calcitriol] affects the expression of CYP24A1 mRNA
CTD PMID:15913539 NCBI chr 3:168,097,484...168,111,920
Ensembl chr 3:168,097,485...168,111,920
JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 affects expression EXP Calcium affects the expression of CYP27B1 mRNA CTD PMID:15913539 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects expression
decreases uptake
EXP
ISO
Calcium affects the expression of CYP2E1 mRNA
CYP2E1 protein results in decreased uptake of Calcium
CTD PMID:15913539, PMID:19028543 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 multiple interactions ISO [CP 199330 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 199331 binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [CP 265298 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [CP 288886 binds to and results in decreased activity of CYSLTR1 protein] which results in decreased abundance of Calcium; [Leukotriene C4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [pranlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; [Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium; [zafirlukast binds to and results in decreased activity of CYSLTR1 protein] which affects the abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]; montelukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; montelukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pobilukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; pranlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; verlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [[Uridine Diphosphate binds to and results in increased activity of CYSLTR1 protein] which results in increased abundance of Calcium]; zafirlukast inhibits the reaction [CYSLTR1 protein promotes the reaction [Leukotriene D4 results in increased abundance of Calcium]] CTD PMID:8014876, PMID:9934474, PMID:10391245, PMID:10462554, PMID:10509933, PMID:11093801, PMID:11705452, PMID:12853847, PMID:15792791, PMID:15990778, PMID:18704935, PMID:20083671 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 multiple interactions ISO [Leukotriene C4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene C4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene D4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; [Leukotriene E4 results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium; BAY u9773 inhibits the reaction [[Leukotriene D4 binds to and results in increased activity of CYSLTR2 protein] which results in increased abundance of Calcium] CTD PMID:10851239, PMID:11093801 NCBI chr15:54,903,290...54,941,742
Ensembl chr15:54,905,274...54,906,203
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 affects expression EXP Calcium affects the expression of DDR1 mRNA CTD PMID:15913539 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780
JBrowse link
G Dmd dystrophin increases abundance
multiple interactions
ISO DMD gene mutant form results in increased abundance of Calcium
Nifedipine inhibits the reaction [DMD gene mutant form results in increased abundance of Calcium]
CTD PMID:24349043 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions
decreases transport
ISO [DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJB11 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr11:81,741,342...81,757,806
Ensembl chr11:81,741,297...81,757,813
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions
decreases transport
ISO [DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of DRD1 protein] which results in increased abundance of Calcium CTD PMID:14622123 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO
EXP
[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; [Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium; Sulpiride inhibits the reaction [[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]; Sulpiride inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]
[DRD2 protein affects the abundance of Calcium] which results in decreased transport of Barium
CTD PMID:8032591, PMID:11124974 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 increases phosphorylation EXP Calcium results in increased phosphorylation of DRD3 protein CTD PMID:19217379 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions EXP Calcium affects the reaction [Potassium Chloride results in increased expression of DUSP1 mRNA] CTD PMID:11577072 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Edn1 endothelin 1 increases abundance
increases uptake
multiple interactions
affects transport
affects localization
EXP
ISO
EDN1 protein results in increased abundance of Calcium
EDN1 protein results in increased uptake of Calcium
EDN1 protein affects the localization of and affects the abundance of Calcium
Carvedilol inhibits the reaction [EDN1 protein results in increased import of and results in increased abundance of Calcium]; EDN1 protein affects the abundance of and affects the localization of Calcium; EDN1 protein results in increased import of and results in increased abundance of Calcium; Glucose affects the reaction [EDN1 protein affects the abundance of and affects the localization of Calcium]; Heparin inhibits the reaction [EDN1 protein results in increased abundance of Calcium]
EDN1 protein affects the transport of Calcium
EDN1 protein results in increased transport of and results in increased abundance of Calcium; Propofol inhibits the reaction [EDN1 protein affects the transport of Calcium]
EDN1 protein affects the localization of Calcium
CTD PMID:1443220, PMID:9138053, PMID:11425647, PMID:12628492, PMID:12821678, PMID:14711191, PMID:27226631 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn2 endothelin 2 increases uptake
multiple interactions
ISO EDN2 protein results in increased uptake of Calcium
EDN2 protein affects the localization of and affects the abundance of Calcium
CTD PMID:11425647 NCBI chr 5:139,098,472...139,106,396
Ensembl chr 5:139,100,898...139,105,792
JBrowse link
G Edn3 endothelin 3 multiple interactions
increases uptake
ISO
EXP
EDN3 protein affects the localization of and affects the abundance of Calcium
BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [APP protein results in increased uptake of Calcium]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]
EDN3 protein results in increased uptake of Calcium
CTD PMID:11425647, PMID:12383957, PMID:15695168 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Ednra endothelin receptor type A affects activity EXP Calcium affects the activity of EDNRA protein CTD PMID:12628492 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Eef2 eukaryotic translation elongation factor 2 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of EEF2 mRNA CTD PMID:15913539 NCBI chr 7:11,401,501...11,406,771
Ensembl chr 7:11,401,501...11,406,771
JBrowse link
G Egf epidermal growth factor increases abundance
multiple interactions
increases transport
affects expression
ISO
EXP
EGF protein results in increased abundance of Calcium
[IGF2 protein co-treated with EGF protein] results in increased import of Calcium
EGF protein results in increased transport of Calcium
[Calcium co-treated with Calcitriol] affects the expression of EGF mRNA
RTKI cpd inhibits the reaction [EGF protein results in increased abundance of Calcium]
Calcium affects the expression of EGF mRNA
CTD PMID:2442157, PMID:11527950, PMID:15913539, PMID:24990931 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP Calcium affects the phosphorylation of and affects the expression of EGFR protein CTD PMID:8393775 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [[CXCL9 protein binds to and results in increased activity of CXCR3 protein] which results in increased abundance of Calcium] which results in increased expression of EGR1 mRNA; [Ionomycin results in increased abundance of Calcium] which results in increased expression of EGR1 protein CTD PMID:12517959 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO Calcium promotes the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26609140 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of EIF4A2 mRNA CTD PMID:15913539 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:12935885 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Ephx2 epoxide hydrolase 2 affects expression EXP Calcium affects the expression of EPHX2 mRNA CTD PMID:15913539 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G F2 coagulation factor II increases abundance
increases localization
multiple interactions
increases uptake
ISO F2 protein results in increased abundance of Calcium
F2 protein results in increased localization of Calcium
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [F2 protein results in increased localization of Calcium]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [F2 protein results in increased localization of Calcium]; Apigenin inhibits the reaction [F2 protein results in increased localization of Calcium]; arsenite inhibits the reaction [F2 protein results in increased abundance of Calcium]; Genistein inhibits the reaction [F2 protein results in increased localization of Calcium]; Nickel inhibits the reaction [F2 protein results in increased uptake of Calcium]; Quercetin inhibits the reaction [F2 protein results in increased localization of Calcium]
CTD PMID:2125206, PMID:19814731, PMID:22244921 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F2r coagulation factor II (thrombin) receptor multiple interactions ISO [Peptides results in increased activity of F2R protein] which results in increased abundance of Calcium CTD PMID:15086339 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]] CTD PMID:16793902 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G F2rl3 F2R like thrombin or trypsin receptor 3 multiple interactions ISO F2RL3 protein affects the localization of and affects the transport of Calcium
[alanyl-tyrosyl-prolyl-glycyl-lysyl-phenylalanine binds to and results in increased activity of F2RL3 protein] which results in increased uptake of Calcium
CTD PMID:16702038, PMID:17707436 NCBI chr16:18,817,797...18,819,790
Ensembl chr16:18,814,622...18,819,833
JBrowse link
G F8 coagulation factor VIII multiple interactions ISO [Copper co-treated with Calcium] results in increased activity of [F8 protein alternative form binds to F8 protein alternative form]; Calcium results in increased activity of [F8 protein alternative form binds to F8 protein alternative form] CTD PMID:11513607 NCBI chr18:367,862...399,242
Ensembl chr18:367,862...399,242
JBrowse link
G Faslg Fas ligand multiple interactions
affects localization
ISO bafilomycin A1 inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]; CD38 protein inhibits the reaction [CD38 gene mutant form inhibits the reaction [FASL protein affects the localization of Calcium]]; Ryanodine inhibits the reaction [FASL protein affects the localization of Calcium] CTD PMID:20200208 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression EXP Calcium results in increased expression of FGF1 protein CTD PMID:15264218 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf23 fibroblast growth factor 23 affects expression ISO Calcium affects the expression of FGF23 mRNA; Calcium affects the expression of FGF23 protein CTD PMID:15086938, PMID:16381997 NCBI chr 4:159,622,404...159,630,082
Ensembl chr 4:159,622,404...159,630,082
JBrowse link
G Fgf9 fibroblast growth factor 9 affects expression EXP Calcium affects the expression of FGF9 mRNA CTD PMID:15913539 NCBI chr15:38,341,657...38,386,945
Ensembl chr15:38,341,089...38,387,316
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of FGFR1 mRNA CTD PMID:15913539 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fis1 fission, mitochondrial 1 affects expression EXP Calcium affects the expression of FIS1 mRNA CTD PMID:15913539 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A multiple interactions ISO FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein] CTD PMID:17872463 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B multiple interactions ISO FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]; Ryanodine inhibits the reaction [FKBP1B gene mutant form inhibits the reaction [Acetylcholine affects the localization of and affects the abundance of Calcium]] CTD PMID:17261647 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) affects expression EXP Calcium affects the expression of FURIN mRNA CTD PMID:15913539 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
G Fxyd2 FXYD domain-containing ion transport regulator 2 multiple interactions
decreases activity
ISO Calcium inhibits the reaction [FXYD2 protein results in increased transport of Deoxyglucose]; Calcium inhibits the reaction [FXYD2 protein results in increased transport of Inulin]
Calcium results in decreased activity of FXYD2 protein
CTD PMID:11533133 NCBI chr 8:49,710,334...49,717,492
Ensembl chr 8:49,710,477...49,716,955
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 affects expression EXP Calcium affects the expression of G6PC mRNA CTD PMID:15913539 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions
affects expression
ISO
EXP
Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]
Calcium affects the expression of GABBR1 mRNA
CTD PMID:15627515, PMID:15913539 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions ISO Calcium promotes the reaction [3-aminopropylphosphinic acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]; Calcium promotes the reaction [CGP 55845A inhibits the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]]; Calcium promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]] CTD PMID:15627515 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gast gastrin multiple interactions ISO Calcium promotes the reaction [Colforsin results in increased secretion of GAST protein]; Calcium promotes the reaction [Terbutaline results in increased secretion of GAST protein] CTD PMID:9277405 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484
JBrowse link
G Gata1 GATA binding protein 1 affects expression EXP Calcium affects the expression of GATA1 mRNA CTD PMID:15913539 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gc GC, vitamin D binding protein affects expression EXP Calcium affects the expression of GC mRNA CTD PMID:15913539 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gcg glucagon multiple interactions EXP Calcium affects the reaction [Pyruvic Acid results in increased secretion of GCG protein] CTD PMID:15919803 NCBI chr 3:48,442,635...48,451,650
Ensembl chr 3:48,442,635...48,451,650
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of GCLC mRNA CTD PMID:15913539 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions EXP Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of GFAP protein]; Calcium deficiency inhibits the reaction [Ethanol results in increased expression of GFAP protein] CTD PMID:17888892, PMID:21879721 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Ghr growth hormone receptor affects expression
multiple interactions
EXP Calcium affects the expression of GHR mRNA
[Calcium co-treated with Calcitriol] affects the expression of GHR mRNA
CTD PMID:15913539 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Gipc3 GIPC PDZ domain containing family, member 3 affects uptake ISO GIPC3 protein affects the uptake of Calcium CTD PMID:27462107 NCBI chr 7:11,245,160...11,253,080
Ensembl chr 7:11,245,875...11,250,708
JBrowse link
G Glrx3 glutaredoxin 3 affects response to substance EXP GLRX3 protein affects the susceptibility to Calcium CTD PMID:16809552 NCBI chr 1:209,768,696...209,799,912
Ensembl chr 1:209,768,696...209,799,903
JBrowse link
G Gnai2 G protein subunit alpha i2 affects expression EXP Calcium affects the expression of GNAI2 mRNA CTD PMID:15913539 NCBI chr 8:116,370,730...116,391,337
Ensembl chr 8:116,370,744...116,391,307
JBrowse link
G Gnas GNAS complex locus multiple interactions ISO [[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium CTD PMID:23022524 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gpbar1 G protein-coupled bile acid receptor 1 multiple interactions ISO [Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased abundance of Calcium
[[6alpha-ethyl-23(S)-methylcholic acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium; [[Oleanolic Acid binds to and results in increased activity of GPBAR1 protein] which results in increased activity of GNAS protein] which results in increased abundance of Calcium
CTD PMID:23022524 NCBI chr 9:81,555,914...81,560,931
Ensembl chr 9:81,559,605...81,560,594
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 multiple interactions EXP Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists results in decreased phosphorylation of GRIA1 protein] CTD PMID:28404816 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 multiple interactions EXP Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] CTD PMID:28404816 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grm1 glutamate metabotropic receptor 1 multiple interactions EXP 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; [3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium]; GRM1 protein promotes the reaction [Propionates results in increased transport of Calcium]; Ruthenium Red inhibits the reaction [[3,5-dihydroxyphenylglycine results in increased activity of GRM1 protein] which results in increased abundance of Calcium] CTD PMID:14622174, PMID:24582715 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP [Calcium co-treated with Zinc] affects the reaction [monoisoamyl-2,3-dimercaptosuccinate affects the reaction [sodium arsenite results in decreased activity of GSR protein]]; [Calcium co-treated with Zinc] affects the reaction [sodium arsenite results in decreased activity of GSR protein]; [Carmustine results in decreased activity of GSR protein] which results in increased uptake of Calcium; Calcium affects the reaction [sodium arsenite results in decreased activity of GSR protein] CTD PMID:15321730, PMID:24184500 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 multiple interactions ISO Calcium affects the reaction [HECTD4 gene SNP affects the abundance of Lead] CTD PMID:28212632 NCBI chr12:40,712,078...40,860,930
Ensembl chr12:40,713,841...40,822,159
JBrowse link
G Hes1 hes family bHLH transcription factor 1 affects expression EXP Calcium affects the expression of HES1 mRNA CTD PMID:15913539 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hgf hepatocyte growth factor increases abundance EXP HGF protein results in increased abundance of Calcium CTD PMID:10963052 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 affects expression EXP Calcium affects the expression of HMGCS2 mRNA CTD PMID:15913539 NCBI chr 2:200,452,623...200,480,785
Ensembl chr 2:200,452,624...200,479,423
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Calcium affects the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] CTD PMID:21443188 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha affects expression EXP Calcium affects the expression of HNF4A mRNA CTD PMID:15913539 NCBI chr 3:159,902,441...159,965,003
Ensembl chr 3:159,902,441...159,965,003
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D multiple interactions EXP Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR] CTD PMID:18583400 NCBI chr14:11,256,163...11,274,684
Ensembl chr14:11,256,268...11,274,578
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U affects expression EXP Calcium affects the expression of SP120 mRNA CTD PMID:15913539 NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions EXP HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]] CTD PMID:12887973 NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
JBrowse link
G Hpca hippocalcin decreases response to substance ISO HPCA protein results in decreased susceptibility to Calcium CTD PMID:12445469 NCBI chr 5:147,295,124...147,305,757
Ensembl chr 5:147,294,820...147,303,346
JBrowse link
G Hrh1 histamine receptor H 1 multiple interactions
increases abundance
ISO [6-((2-(4-imidazolyl)ethyl)amino)heptanoic acid 4-toluidide binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium; [HRH1 protein binds to Histamine] which results in increased import of Calcium; [HRH1 protein binds to Lidocaine] which results in increased import of Calcium; [HRH1 protein binds to Procaine] which results in increased import of Calcium; [HRH1 protein binds to Tetracaine] which results in increased import of Calcium; fexofenadine inhibits the reaction [[Histamine binds to and results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]; Triprolidine inhibits the reaction [[Histamine results in increased activity of HRH1 protein] which results in increased abundance of Calcium]; Triprolidine inhibits the reaction [HRH1 protein promotes the reaction [Histamine results in increased export of Calcium]]
HRH1 protein results in increased abundance of Calcium
CTD PMID:2419744, PMID:11238657, PMID:11527950, PMID:19443731, PMID:32061592 NCBI chr 4:146,374,596...146,458,148
Ensembl chr 4:146,455,332...146,457,074
JBrowse link
G Hrh3 histamine receptor H3 multiple interactions ISO [4-(1H-imidazol-4-ylmethyl)piperidine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Histamine binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [imetit binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; [Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium; clobenpropit inhibits the reaction [[Methylhistamines binds to and results in increased activity of HRH3 protein] which results in increased transport of Calcium] CTD PMID:12706455 NCBI chr 3:175,474,310...175,479,395
Ensembl chr 3:175,473,078...175,479,395
JBrowse link
G Hrh4 histamine receptor H4 multiple interactions ISO 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; 1-((5-chloro-1H-indol-2-yl)carbonyl)-4-methylpiperazine inhibits the reaction [[clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium]; [4-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [alpha-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [clobenpropit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [Histamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [imetit binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium; [N-methylhistamine binds to and results in increased activity of HRH4 protein] which results in increased abundance of Calcium CTD PMID:11181941, PMID:17507084 NCBI chr18:4,365,429...4,382,599
Ensembl chr18:4,365,429...4,382,599
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of HSD17B12 mRNA CTD PMID:15913539 NCBI chr 3:82,924,699...83,048,465
Ensembl chr 3:82,924,687...83,048,435
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]] CTD PMID:23184943 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
decreases transport
ISO [DNAJB11 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [DNAJC3 protein binds to HSPA5 protein] which results in decreased transport of Calcium; [HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [HSPA5 protein results in decreased transport of Calcium] which results in increased susceptibility to Thapsigargin CTD PMID:26085089 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases activity ISO Calcium results in increased activity of HTR1A protein CTD PMID:11356925 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions EXP HTR2A protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:16901936 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B multiple interactions ISO Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:18758753 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions EXP HTR7 protein promotes the reaction [[Freund's Adjuvant results in increased activity of TRPV1 protein] which results in increased transport of Calcium] CTD PMID:16901936 NCBI chr 1:254,547,964...254,671,811
Ensembl chr 1:254,547,620...254,671,778
JBrowse link
G Ifng interferon gamma multiple interactions ISO KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]]
[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]; [TNF protein co-treated with IFNG protein] promotes the reaction [Diclofenac affects the abundance of Calcium]; Calcium promotes the reaction [[Diclofenac co-treated with IFNG protein] results in increased phosphorylation of STAT1 protein]
CTD PMID:23747339, PMID:26609140 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ift88 intraflagellar transport 88 multiple interactions
increases uptake
ISO Gadolinium inhibits the reaction [IFT88 protein mutant form results in increased uptake of Calcium]; IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium] CTD PMID:16396941 NCBI chr15:37,690,417...37,786,855
Ensembl chr15:37,691,345...37,784,924
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression
multiple interactions
increases import
EXP
ISO
Calcium affects the expression of IGF1 mRNA
Cobalt inhibits the reaction [IGF1 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF1 protein results in increased import of Calcium]
CTD PMID:1550224, PMID:2460452, PMID:2539779, PMID:15913539 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2 insulin-like growth factor 2 multiple interactions
increases import
ISO [IGF2 protein co-treated with EGF protein] results in increased import of Calcium; Cobalt inhibits the reaction [IGF2 protein results in increased import of Calcium]; Lanthanum inhibits the reaction [IGF2 protein results in increased import of Calcium]; Pertussis Toxin inhibits the reaction [IGF2 protein results in increased import of Calcium]; tetramethrin inhibits the reaction [IGF2 protein results in increased import of Calcium] CTD PMID:2442157, PMID:2460452, PMID:2539779 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression EXP Calcium affects the expression of IGFBP2 mRNA CTD PMID:15913539 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 affects expression
decreases degradation
EXP Calcium affects the expression of IGFBP5 mRNA
Calcium results in decreased degradation of IGFBP5 protein
CTD PMID:8894652, PMID:15913539 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Il11 interleukin 11 multiple interactions
increases abundance
ISO Flurbiprofen inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium]; IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium]; Indomethacin inhibits the reaction [IL11 protein results in increased abundance of Calcium]; TNFRSF11B protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr 1:72,636,959...72,643,255
Ensembl chr 1:72,635,267...72,643,255
JBrowse link
G Il13 interleukin 13 multiple interactions ISO IL13 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]] CTD PMID:23747339 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 multiple interactions ISO IL4 protein inhibits the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO Calcimycin inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]; Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]; Edetic Acid inhibits the reaction [Calcium promotes the reaction [Histamine results in increased expression of IL6 protein]]
Calcium results in increased expression of IL6 mRNA
CTD PMID:11238657, PMID:20682585 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6st interleukin 6 signal transducer multiple interactions ISO IL6ST protein promotes the reaction [IL11 protein results in increased abundance of Calcium] CTD PMID:12110441 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Ilf3 interleukin enhancer binding factor 3 multiple interactions ISO Calcium affects the reaction [Vanadates results in increased activity of ILF3 protein] CTD PMID:10623810 NCBI chr 8:22,402,877...22,440,984
Ensembl chr 8:22,402,890...22,440,885
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 multiple interactions ISO Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein] CTD PMID:16369480 NCBI chr 1:142,525,041...142,615,673
Ensembl chr 1:142,525,046...142,615,673
JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]; TRPV4 protein promotes the reaction [ITGA2 protein promotes the reaction [[Dinoprostone co-treated with Serotonin] results in increased import of Calcium]] CTD PMID:18234883 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itgb1bp2 integrin subunit beta 1 binding protein 2 multiple interactions ISO Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to SUGT1 protein]]
Calcium promotes the reaction [Adenosine Diphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]; Calcium promotes the reaction [Adenosine Triphosphate promotes the reaction [ITGB1BP2 protein binds to HSP90AA1 protein]]
CTD PMID:23184943 NCBI chr  X:71,342,770...71,347,623
Ensembl chr  X:71,342,775...71,347,619
JBrowse link
G Itih1 inter-alpha trypsin inhibitor, heavy chain 1 multiple interactions ISO Calcium promotes the reaction [ITIH1 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr16:7,012,376...7,026,542
Ensembl chr16:7,012,354...7,026,540
JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 multiple interactions ISO Calcium promotes the reaction [ITIH2 protein binds to TNFAIP6 protein] CTD PMID:16768462 NCBI chr17:72,160,734...72,197,248
Ensembl chr17:72,160,735...72,195,509
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO ITPR1 protein promotes the reaction [Acetaldehyde metabolite results in increased abundance of Calcium]; ITPR1 protein promotes the reaction [Ethanol metabolite results in increased abundance of Calcium] CTD PMID:17241155 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 multiple interactions ISO 2-aminoethoxydiphenyl borate inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium]; [adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium; xestospongin C inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium] CTD PMID:15201137 NCBI chr 4:180,423,452...180,800,088
Ensembl chr 4:180,538,389...180,722,358
JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 affects expression EXP Calcium affects the expression of ITPR3 protein CTD PMID:10963052 NCBI chr20:5,645,894...5,711,702
Ensembl chr20:5,646,097...5,711,702
JBrowse link
G Ivl involucrin increases expression
multiple interactions
ISO Calcium results in increased expression of IVL mRNA
NPS R-467 promotes the reaction [Calcium results in increased expression of IVL mRNA]
CTD PMID:10469331 NCBI chr 2:192,761,171...192,773,346
Ensembl chr 2:192,761,538...192,763,577
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium] CTD PMID:20107083 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 increases activity
multiple interactions
ISO Calcium results in increased activity of KCNE1 protein
W 7 inhibits the reaction [Calcium results in increased activity of KCNE1 protein]
CTD PMID:1655403 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions EXP Nimodipine inhibits the reaction [KCNH2 protein affects the abundance of Calcium] CTD PMID:11040061 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 multiple interactions
affects abundance
ISO Dantrolene inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium]; KCNJ11 protein affects the reaction [[Manganese co-treated with Dobutamine] results in increased abundance of Calcium]; W 7 inhibits the reaction [KCNJ11 protein mutant form results in increased abundance of Calcium]
KCNJ11 protein affects the abundance of Calcium
CTD PMID:17189350 NCBI chr 1:102,103,093...102,107,134
Ensembl chr 1:102,103,094...102,106,127
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions
increases response to substance
ISO
EXP
[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium]
KCNMA1 mRNA alternative form results in increased susceptibility to Calcium
CTD PMID:22123969, PMID:28090300 NCBI chr15:344,204...1,048,849
Ensembl chr15:344,360...1,047,956
JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 multiple interactions ISO [KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium; Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium] CTD PMID:22123969 NCBI chr10:18,910,586...18,922,856
Ensembl chr10:18,906,010...18,919,639
JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 increases activity
multiple interactions
ISO Calcium results in increased activity of KCNN2 protein
cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN2 protein]
CTD PMID:17486140 NCBI chr18:39,331,894...39,479,574
Ensembl chr18:39,335,377...39,479,257
JBrowse link
G Kcnn3 potassium calcium-activated channel subfamily N member 3 multiple interactions
increases activity
ISO 6,7-dichloro-1H-indole-2,3-dione 3-oxime promotes the reaction [Calcium results in increased activity of KCNN3 protein]; cyclohexyl-(2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl)amine promotes the reaction [Calcium results in increased activity of KCNN3 protein] CTD PMID:17486140 NCBI chr 2:188,837,280...188,991,794
Ensembl chr 2:188,844,073...188,988,774
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 affects abundance
multiple interactions
ISO KCNN4 protein affects the abundance of Calcium
KCNN4 protein affects the reaction [Calcium results in increased transport of Potassium]
CTD PMID:11826162, PMID:14985237 NCBI chr 1:81,227,855...81,245,986
Ensembl chr 1:81,230,612...81,245,996
JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO [VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium; TRPC6 protein promotes the reaction [[VEGFA protein results in increased activity of KDR protein] which results in increased abundance of Calcium]
Calcium promotes the reaction [Corticosterone results in decreased expression of KDR protein]
CTD PMID:14551041, PMID:21647420 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Khsrp KH-type splicing regulatory protein multiple interactions EXP Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR] CTD PMID:18583400 NCBI chr 9:10,013,795...10,023,670
Ensembl chr 9:10,013,854...10,022,924
JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor multiple interactions ISO 2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] CTD PMID:18948403 NCBI chr13:50,529,506...50,537,603
Ensembl chr13:50,529,510...50,535,389
JBrowse link
G Kiss1r KISS1 receptor multiple interactions ISO 2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; [KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium; Flufenamic Acid inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]; Tetrodotoxin promotes the reaction [2-aminoethyl diphenylborinate inhibits the reaction [[KISS1 protein results in increased activity of KISS1R protein] which results in increased abundance of Calcium]] CTD PMID:18948403 NCBI chr 7:12,606,210...12,609,868
Ensembl chr 7:12,606,210...12,609,868
JBrowse link
G Kl Klotho affects abundance
multiple interactions
ISO KL protein affects the abundance of Calcium
KL protein inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] inhibits the reaction [TRPV5 protein results in increased uptake of Calcium]]
CTD PMID:11796525, PMID:23747339 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Klk1 kallikrein 1 decreases activity ISO Calcium results in decreased activity of KLK1 protein CTD PMID:15558947 NCBI chr 1:100,131,562...100,135,556
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
Ensembl chr 1:100,059,967...100,203,329
JBrowse link
G Klk8 kallikrein related-peptidase 8 increases activity ISO Calcium results in increased activity of KLK8 protein CTD PMID:16800733 NCBI chr 1:99,735,168...99,742,011
Ensembl chr 1:99,734,993...99,742,009
JBrowse link
G Kng2 kininogen 2 multiple interactions
increases abundance
affects abundance
ISO
EXP
BDKRB2 protein affects the reaction [KNG1 protein affects the abundance of Calcium]
KNG1 protein modified form results in increased abundance of Calcium
B 4162 inhibits the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; BDKRB2 protein affects the reaction [pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]]; CALR protein promotes the reaction [KNG1 protein modified form results in increased abundance of Calcium]; KNG1 protein affects the transport of and affects the localization of Calcium; pyranoprofen inhibits the reaction [KNG1 protein affects the transport of and affects the localization of Calcium]
[KNG1 protein alternative form co-treated with Calcium] results in increased secretion of CALCA protein; Calcium affects the reaction [KNG1 protein results in increased secretion of Excitatory Amino Acid Agents]
KNG1 protein results in increased abundance of Calcium
CTD PMID:7961812, PMID:8592139, PMID:10535458, PMID:12582005, PMID:16473424, PMID:17666428, PMID:18054572 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Krt1 keratin 1 multiple interactions
increases expression
ISO 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 15-hydroxy-5,8,11,13-eicosatetraenoic acid inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; 8-hydroxyeicosatetraenoic acid promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; Masoprocol inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; morin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; Quercetin inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of KRT1 protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of KRT1 protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of KRT1 protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of KRT1 protein]
Calcium results in increased expression of KRT1 mRNA; Calcium results in increased expression of KRT1 protein
CTD PMID:12069687, PMID:21524694, PMID:24658506 NCBI chr 7:143,448,318...143,453,544
Ensembl chr 7:143,448,318...143,453,544
JBrowse link
G Lep leptin affects abundance
multiple interactions
affects secretion
increases transport
affects expression
decreases abundance
ISO
EXP
LEP protein affects the abundance of Calcium
Calcium deficiency inhibits the reaction [[Glucose co-treated with INS1 protein] results in increased secretion of LEP protein]
Calcium deficiency affects the secretion of LEP protein
LEP protein results in increased transport of Calcium
1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole inhibits the reaction [LEP protein results in increased transport of Calcium]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [LEP protein results in increased transport of Calcium]; 2-aminoethoxydiphenyl borate inhibits the reaction [LEP protein results in increased transport of Calcium]; acetovanillone inhibits the reaction [LEP protein affects the abundance of Calcium]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [LEP protein results in increased transport of Calcium]; BQ 788 inhibits the reaction [LEP protein affects the abundance of Calcium]; Calcium promotes the reaction [LEP protein results in increased transport of Calcium]; cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [LEP protein affects the abundance of Calcium]; edelfosine inhibits the reaction [LEP protein results in increased transport of Calcium]; Flufenamic Acid inhibits the reaction [LEP protein results in increased transport of Calcium]; JAK2 protein promotes the reaction [LEP protein results in increased transport of Calcium]; Lanthanum promotes the reaction [LEP protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC1 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC4 protein results in increased transport of Calcium]; LEP protein promotes the reaction [TRPC5 protein results in increased transport of Calcium]; Wortmannin inhibits the reaction [LEP protein results in increased transport of Calcium]
Calcium affects the expression of LEP mRNA
LEP protein results in decreased abundance of Calcium
CTD PMID:10780946, PMID:14657008, PMID:15913539, PMID:16380530, PMID:20107083 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lepr leptin receptor affects expression EXP Calcium affects the expression of LEPR mRNA CTD PMID:15913539 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases abundance EXP LIF protein results in increased abundance of Calcium CTD PMID:11073891 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G LOC100912605 olfactory receptor 5D14-like multiple interactions ISO [ethyl vanillin binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium; [Eugenol binds to and results in increased activity of OLFR73 protein] which results in increased transport of Calcium; [Eugenol binds to OLFR73 protein] which results in increased transport of Calcium; [isomethyleugenol binds to and results in decreased activity of OLFR73 protein] which results in decreased transport of Calcium; isomethyleugenol inhibits the reaction [[Eugenol binds to OLFR73 protein] which results in increased transport of Calcium] CTD PMID:14685265, PMID:15716417 NCBI chr 3:76,255,179...76,256,129
Ensembl chr 3:76,255,179...76,256,129
JBrowse link
G Loricrin loricrin cornified envelope precursor protein increases expression
multiple interactions
ISO Calcium results in increased expression of LORICRIN mRNA; Calcium results in increased expression of LORICRIN protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Calcium results in increased expression of LORICRIN protein]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CASR mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; CTNNB1 mutant form inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN mRNA]; SB 203580 inhibits the reaction [Calcium results in increased expression of LORICRIN protein]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN mRNA]; WNT5A protein promotes the reaction [Calcium results in increased expression of LORICRIN protein]
CTD PMID:21524694, PMID:24658506 NCBI chr 2:191,984,455...191,990,713
Ensembl chr 2:191,984,773...191,986,170
JBrowse link
G Lypla1 lysophospholipase 1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of LYPLA1 mRNA CTD PMID:15913539 NCBI chr 5:14,559,333...14,588,447
Ensembl chr 5:14,559,334...14,588,422
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP [Sumatriptan results in increased abundance of Calcium] inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA]; Calcium inhibits the reaction [MAP2K1 protein results in increased expression of CALCA mRNA] CTD PMID:12574409 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP Calcium affects the expression of MAP2K2 mRNA CTD PMID:15913539 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
Calcium results in increased phosphorylation of MAPK1 protein
Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK1 protein]
Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]
Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:10660688, PMID:15086530, PMID:16877402, PMID:17537980, PMID:18758753, PMID:19782052, PMID:26609140 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression EXP Calcium affects the expression of MAPK14 mRNA CTD PMID:15913539 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
Calcium results in increased phosphorylation of MAPK3 protein
Calcium promotes the reaction [Diclofenac results in increased phosphorylation of MAPK3 protein]
Calcium deficiency inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Calcium affects the reaction [Ptychodiscus brevis T2 toxin affects the phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]; Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK3 protein]
CTD PMID:10660688, PMID:15086530, PMID:16877402, PMID:17537980, PMID:18758753, PMID:19782052, PMID:26609140 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk4 mitogen-activated protein kinase 4 affects expression EXP Calcium affects the expression of MAPK4 mRNA CTD PMID:15913539 NCBI chr18:69,894,692...70,043,634
Ensembl chr18:69,894,684...69,944,632
JBrowse link
G Marco macrophage receptor with collagenous structure multiple interactions ISO Calcium promotes the reaction [titanium dioxide binds to MARCO protein] CTD PMID:18836211 NCBI chr16:85,115,199...85,147,683
Ensembl chr16:85,115,201...85,135,859
JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 multiple interactions ISO [NAADP results in increased activity of MCOLN1 protein] which affects the localization of Calcium CTD PMID:21613607 NCBI chr12:2,054,629...2,068,682
Ensembl chr12:2,054,680...2,068,682
JBrowse link
G Mcu mitochondrial calcium uniporter affects localization ISO MCU protein affects the localization of Calcium CTD PMID:22829870 NCBI chr20:29,037,452...29,199,224
Ensembl chr20:29,038,480...29,199,224
JBrowse link
G Mgp matrix Gla protein multiple interactions
affects expression
affects binding
ISO
EXP
[Calcium binds to MGP protein] which binds to and results in decreased activity of BMP4 protein; [Edetic Acid inhibits the reaction [Calcium binds to MGP protein]] inhibits the reaction [MGP protein binds to BMP4 protein]; Edetic Acid inhibits the reaction [Calcium binds to MGP protein]
Calcium affects the expression of MGP mRNA
CTD PMID:15913539, PMID:18369157 NCBI chr 4:170,856,783...170,860,105
Ensembl chr 4:170,856,751...170,860,225
JBrowse link
G Mmp1 matrix metallopeptidase 1 affects expression ISO Calcium affects the expression of MMP1 mRNA; Calcium affects the expression of MMP1 protein CTD PMID:17508023 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of MTOR protein] CTD PMID:12935885 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mybpc3 myosin binding protein C3 increases response to substance
multiple interactions
ISO MYBPC3 gene mutant form results in increased susceptibility to Calcium
epigallocatechin gallate inhibits the reaction [MYBPC3 gene mutant form results in increased susceptibility to Calcium]
CTD PMID:27994558 NCBI chr 3:79,940,509...79,958,731
Ensembl chr 3:79,940,561...79,958,730
JBrowse link
G Myh7 myosin heavy chain 7 increases transport ISO MYH7 gene mutant form results in increased transport of Calcium CTD PMID:29741611 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myl2 myosin light chain 2 multiple interactions ISO Calcium affects the reaction [MYL2 gene SNP affects the abundance of Lead] CTD PMID:28212632 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
JBrowse link
G Myl3 myosin light chain 3 affects expression EXP Calcium affects the expression of MYL3 mRNA CTD PMID:15913539 NCBI chr 8:119,030,852...119,036,996
Ensembl chr 8:119,030,875...119,036,996
JBrowse link
G Myl9 myosin light chain 9 multiple interactions
affects phosphorylation
decreases phosphorylation
EXP [[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; [CACNA1D protein results in increased uptake of Calcium] which results in increased phosphorylation of MYL9 protein; [Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein; Glycodeoxycholic Acid inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein]; Y 27632 inhibits the reaction [[Escin affects the susceptibility to Calcium] which results in increased phosphorylation of MYL9 protein]
Calcium affects the phosphorylation of MYL9 protein
Calcium deficiency results in decreased phosphorylation of MYL9 protein
CTD PMID:7503253, PMID:9618396, PMID:17272349, PMID:29660437 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Mylk myosin light chain kinase increases activity
multiple interactions
ISO
EXP
Calcium deficiency results in increased activity of MYLK protein; Calcium results in increased activity of MYLK protein
[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein
ML 7 inhibits the reaction [Calcium deficiency results in increased activity of MYLK protein]
CTD PMID:9618396, PMID:10640419, PMID:11054866 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Myo1b myosin Ib increases activity EXP Calcium deficiency results in increased activity of MYO1B protein CTD PMID:10419463 NCBI chr 9:54,706,005...54,766,054
Ensembl chr 9:54,558,202...54,766,054
JBrowse link
G Myo5a myosin VA affects activity ISO Calcium affects the activity of MYO5A protein CTD PMID:10660602 NCBI chr 8:82,038,966...82,156,507
Ensembl chr 8:82,037,977...82,156,617
JBrowse link
G Naip6 NLR family, apoptosis inhibitory protein 6 decreases response to substance ISO NAIP protein results in decreased susceptibility to Calcium CTD PMID:12445469 NCBI chr 2:30,377,505...30,418,578 JBrowse link
G Ncf1 neutrophil cytosolic factor 1 affects abundance ISO NCF1 protein affects the abundance of Calcium CTD PMID:16280459 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of NDUFS1 mRNA CTD PMID:15913539 NCBI chr 9:69,919,863...69,953,182
Ensembl chr 9:69,919,867...69,953,182
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase affects expression EXP Calcium affects the expression of NEDD4 mRNA CTD PMID:15913539 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase multiple interactions ISO [NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium; Thiazides inhibits the reaction [[NEDD4L gene mutant form results in increased susceptibility to Sodium, Dietary] which results in increased abundance of Calcium] CTD PMID:23348737 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Nefl neurofilament light multiple interactions EXP Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFL protein]; calpeptin inhibits the reaction [Calcium results in increased degradation of NEFL protein]; Indomethacin inhibits the reaction [Calcium results in increased degradation of NEFL protein] CTD PMID:11071371, PMID:21879721 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nefm neurofilament medium multiple interactions EXP Calcium affects the reaction [diphenylditelluride results in increased phosphorylation of NEFM protein] CTD PMID:21879721 NCBI chr15:44,855,307...44,860,604
Ensembl chr15:44,855,310...44,860,604
JBrowse link
G Nek9 NIMA-related kinase 9 affects expression EXP Calcium affects the expression of NEK9 mRNA CTD PMID:15913539 NCBI chr 6:109,121,524...109,162,433
Ensembl chr 6:109,124,330...109,162,267
JBrowse link
G Nf1 neurofibromin 1 decreases transport ISO NF1 protein results in decreased transport of Calcium CTD PMID:21949590 NCBI chr10:66,732,460...66,928,706
Ensembl chr10:66,690,133...66,928,903
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions ISO 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Muscarine co-treated with Calcium] affects the localization of NFATC2 protein]; 4-methyl-4'-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-1,2,3-thiadiazole-5-carboxanilide inhibits the reaction [[Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein]; [Muscarine co-treated with Calcium] affects the localization of NFATC2 protein; [Thapsigargin co-treated with Calcium] affects the localization of NFATC2 protein CTD PMID:24990931 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases abundance ISO NFE2L2 gene mutant form results in increased abundance of Calcium CTD PMID:29618784 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkbia NFKB inhibitor alpha affects expression
multiple interactions
EXP
ISO
Calcium affects the expression of NFKBIA mRNA
Calcium affects the reaction [Morphine inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]
CTD PMID:15913539, PMID:24068670 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngb neuroglobin affects transport ISO NGB protein affects the transport of Calcium CTD PMID:19154338 NCBI chr 6:111,126,259...111,131,699
Ensembl chr 6:111,126,261...111,132,320
JBrowse link
G Ngf nerve growth factor multiple interactions
increases uptake
EXP [NGF protein co-treated with 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester] results in increased uptake of Calcium; [NGF protein co-treated with Adenosine Triphosphate] results in increased uptake of Calcium; cadmium acetate inhibits the reaction [NGF protein results in increased uptake of Calcium]; Cadmium inhibits the reaction [NGF protein results in increased uptake of Calcium]; calmidazolium inhibits the reaction [NGF protein results in increased uptake of Calcium]; Fluphenazine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Nifedipine inhibits the reaction [NGF protein results in increased uptake of Calcium]; Okadaic Acid promotes the reaction [NGF protein results in increased uptake of Calcium]; Staurosporine inhibits the reaction [NGF protein results in increased uptake of Calcium] CTD PMID:1374475 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Noa1 nitric oxide associated 1 multiple interactions EXP [Tamoxifen results in increased abundance of Calcium] which results in increased activity of NOA1 protein CTD PMID:17283165 NCBI chr14:33,107,868...33,124,172
Ensembl chr14:33,108,024...33,124,171
JBrowse link
G Nos1 nitric oxide synthase 1 multiple interactions EXP [Calcium binds to CALM1 protein] promotes the reaction [NOS1 protein results in increased chemical synthesis of Nitric Oxide]; [Calcium binds to CALM1 protein] which binds to and affects the folding of and results in increased activity of NOS1 protein CTD PMID:17098364 NCBI chr12:44,214,949...44,405,530
Ensembl chr12:44,213,943...44,520,341
JBrowse link
G Nos3 nitric oxide synthase 3 affects response to substance
increases activity
multiple interactions
ISO
EXP
NOS3 protein affects the susceptibility to Calcium
Calcium results in increased activity of NOS3 protein
Calcium affects the reaction [Polycyclic Aromatic Hydrocarbons results in increased expression of and results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [Digitoxin results in increased activity of NOS3 protein]; Calcium deficiency inhibits the reaction [ginsenoside Re results in increased phosphorylation of NOS3 protein]
CTD PMID:15183461, PMID:17403420, PMID:17490654, PMID:19380615, PMID:19446813, PMID:22244921 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO 1-(3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)-4-methoxyphenyl)-2,3,4,9-tetrahydro-1H-pyrido(3,4-b)indole-3-carboxylic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]]; NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] CTD PMID:24912985 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Nppc natriuretic peptide C increases uptake
multiple interactions
EXP NPPC protein results in increased uptake of Calcium
Ammonia inhibits the reaction [NPPC protein results in increased uptake of Calcium]; Nimodipine inhibits the reaction [NPPC protein results in increased uptake of Calcium]
CTD PMID:18222015 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Npr1 natriuretic peptide receptor 1 affects expression EXP Calcium affects the expression of NPR1 mRNA CTD PMID:15913539 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 affects expression EXP Calcium affects the expression of NR0B2 mRNA CTD PMID:15913539 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 affects expression EXP Calcium affects the expression of NR1D2 mRNA CTD PMID:15913539 NCBI chr15:8,730,871...8,757,165
Ensembl chr15:8,730,871...8,757,165
JBrowse link
G Nrxn1 neurexin 1 multiple interactions ISO Calcium affects the reaction [alpha-latrotoxin binds to NRXN1 protein]; Calcium affects the reaction [black widow spider venom binds to NRXN1 protein] CTD PMID:9430716 NCBI chr 6:13,886,757...15,191,660
Ensembl chr 6:13,886,740...15,191,660
JBrowse link
G Nucb2 nucleobindin 2 multiple interactions EXP KT 5720 inhibits the reaction [NUCB2 protein results in increased import of Calcium] CTD PMID:17627999 NCBI chr 1:185,106,773...185,143,278
Ensembl chr 1:185,104,656...185,143,272
JBrowse link
G Ocln occludin multiple interactions ISO Calcium deficiency inhibits the reaction [TJP1 protein binds to OCLN protein] CTD PMID:11054866 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Olr1519 olfactory receptor 1519 multiple interactions ISO [bourgeonal binds to and results in increased activity of OR1D2 protein] which results in increased abundance of Calcium CTD PMID:21454470 NCBI chr10:61,160,125...61,161,060
Ensembl chr10:61,160,125...61,161,060
Ensembl chr10:61,160,125...61,161,060
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 multiple interactions
increases uptake
EXP
ISO
[Calcium affects the activity of and affects the localization of STIM1 protein] which affects the activity of ORAI1 protein
ORAI1 protein results in increased uptake of Calcium
CTD PMID:23212906, PMID:24990931 NCBI chr12:38,981,903...38,995,570
Ensembl chr12:38,981,927...38,995,570
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions ISO
EXP
OXT protein promotes the reaction [TRPC3 protein results in increased transport of Calcium]
[Thapsigargin results in increased transport of Calcium] which results in increased secretion of OXT protein
CTD PMID:12700192, PMID:22028774 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G P2rx3 purinergic receptor P2X 3 multiple interactions ISO [alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[alpha,beta-methyleneadenosine 5'-triphosphate binds to and results in increased activity of P2RX3 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr 3:72,403,992...72,447,801
Ensembl chr 3:72,403,993...72,447,801
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium; KN 62 inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium]; protoberberine analog inhibits the reaction [[3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased activity of P2RX7 protein] which results in increased import of Calcium] CTD PMID:21320518 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G P2ry1 purinergic receptor P2Y1 multiple interactions ISO
EXP
[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium; Calcium affects the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein]; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY1 protein] which results in increased abundance of Calcium]
[N(6)-methyl-2'-deoxyadenosine 3',5'-diphosphate binds to and results in decreased activity of P2RY1 protein] inhibits the reaction [Adenosine Triphosphate results in increased uptake of Calcium]
CTD PMID:12694404, PMID:16236484, PMID:16973929 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G P2ry2 purinergic receptor P2Y2 multiple interactions
affects response to substance
ISO
EXP
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased abundance of Calcium
P2RY2 protein affects the susceptibility to Calcium
[Adenosine Triphosphate results in increased activity of P2RY2 protein] which results in increased uptake of Calcium; Go 6976 promotes the reaction [P2RY2 protein results in increased uptake of Calcium]; Tetradecanoylphorbol Acetate inhibits the reaction [P2RY2 protein results in increased uptake of Calcium]
CTD PMID:11527950, PMID:17003265, PMID:18343036 NCBI chr 1:166,031,228...166,045,423
Ensembl chr 1:166,031,272...166,037,424
JBrowse link
G P2ry4 pyrimidinergic receptor P2Y4 multiple interactions ISO [Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium; Trichloroethylene inhibits the reaction [[Adenosine Triphosphate binds to and results in increased activity of P2RY4 protein] which results in increased abundance of Calcium] CTD PMID:12694404 NCBI chr  X:70,421,599...70,447,109
Ensembl chr  X:70,426,951...70,428,364
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of P4HB mRNA CTD PMID:15913539 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 increases abundance
multiple interactions
ISO PAFAH1B1 protein results in increased abundance of Calcium
Calcium promotes the reaction [PAFAH1B1 protein binds to IQGAP1 protein binds to CDC42 protein]
PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]; PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
CTD PMID:15001556, PMID:16369480 NCBI chr10:61,456,144...61,577,412
Ensembl chr10:61,456,145...61,577,412
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase multiple interactions ISO PARG protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] CTD PMID:20878536 NCBI chr16:8,350,168...8,457,999
Ensembl chr16:8,350,326...8,457,996
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO PARP1 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] CTD PMID:20878536 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pask PAS domain containing serine/threonine kinase multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of PASK mRNA CTD PMID:15913539 NCBI chr 9:100,450,595...100,479,719
Ensembl chr 9:100,450,586...100,479,868
JBrowse link
G Pax6 paired box 6 affects expression EXP Calcium affects the expression of PAX6 mRNA CTD PMID:15913539 NCBI chr 3:95,700,241...95,728,682
Ensembl chr 3:95,707,386...95,728,624
JBrowse link
G Pax8 paired box 8 affects expression EXP Calcium affects the expression of PAX8 mRNA CTD PMID:15913539 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Pcdh19 protocadherin 19 affects binding ISO Calcium binds to PCDH19 protein CTD PMID:18469813 NCBI chr  X:104,387,346...104,493,914
Ensembl chr  X:104,391,607...104,493,757
JBrowse link
G Pdgfb platelet derived growth factor subunit B increases import ISO PDGFB protein results in increased import of Calcium CTD PMID:19576918 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 multiple interactions
affects abundance
ISO PDK1 protein affects the reaction [[Calcium co-treated with Ionomycin] results in increased phosphorylation of AKT1 protein]
PDK1 protein affects the abundance of Calcium
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester affects the reaction [PDK1 protein affects the abundance of Calcium]; [PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium; Adenosine Triphosphate promotes the reaction [PDK1 protein affects the abundance of Calcium]; PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]; tubacin affects the reaction [[PDK1 protein affects the susceptibility to Adenosine Triphosphate] which affects the abundance of Calcium]; tubacin affects the reaction [PDK1 protein affects the abundance of Calcium]; tubacin inhibits the reaction [PDK1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]]
CTD PMID:28634229, PMID:28887310 NCBI chr 3:58,530,870...58,561,494
Ensembl chr 3:58,530,870...58,558,027
JBrowse link
G Pdzd3 PDZ domain containing 3 multiple interactions ISO [[USP2 gene mutant form results in increased expression of PDZD3 protein] which results in increased activity of TRPV6 protein] which results in increased uptake of Calcium CTD PMID:26756164 NCBI chr 8:48,577,905...48,582,353
Ensembl chr 8:48,577,952...48,582,353
JBrowse link
G Pgp phosphoglycolate phosphatase decreases activity ISO Calcium results in decreased activity of PGP protein CTD PMID:24338473 NCBI chr10:13,836,105...13,838,731
Ensembl chr10:13,836,128...13,838,765
JBrowse link
G Pick1 protein interacting with PRKCA 1 multiple interactions EXP Calcium affects the reaction [PICK1 protein binds to AGO2 protein]; Calcium deficiency inhibits the reaction [Excitatory Amino Acid Agonists inhibits the reaction [PICK1 protein binds to AGO2 protein]]; Calcium promotes the reaction [PICK1 protein binds to GRIA2 protein] CTD PMID:28404816 NCBI chr 7:120,465,472...120,484,824
Ensembl chr 7:120,465,130...120,484,840
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta affects transport EXP PIK3CB protein affects the transport of Calcium CTD PMID:11597992 NCBI chr 8:107,275,849...107,381,088
Ensembl chr 8:107,275,725...107,380,933
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta affects transport ISO PIK3CD protein affects the transport of Calcium CTD PMID:16179367 NCBI chr 5:166,602,053...166,628,028
Ensembl chr 5:166,602,053...166,628,028
JBrowse link
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta affects expression EXP Calcium affects the expression of PIP5K1B mRNA CTD PMID:15913539 NCBI chr 1:242,168,462...242,441,247
Ensembl chr 1:242,168,462...242,441,247
JBrowse link
G Pkd1 polycystin 1, transient receptor potential channel interacting multiple interactions ISO PKD1 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
PKD1 protein affects the reaction [Caffeine affects the abundance of Calcium]; PKD1 protein affects the reaction [Thapsigargin affects the abundance of Calcium]
CTD PMID:15001556, PMID:18679710 NCBI chr10:13,914,057...13,962,008
Ensembl chr10:13,915,214...13,962,008
JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel multiple interactions
increases transport
ISO PKD2 protein promotes the reaction [PAFAH1B1 protein results in increased abundance of Calcium]
IFT88 protein affects the reaction [PKD2 protein results in increased uptake of Calcium]
PKD2 protein results in increased transport of Calcium
CTD PMID:15001556, PMID:15100357, PMID:16396941 NCBI chr14:6,602,004...6,645,257
Ensembl chr14:6,602,004...6,645,257
JBrowse link
G Pklr pyruvate kinase L/R multiple interactions EXP Calcium inhibits the reaction [Phenylephrine results in decreased activity of PKLR protein] CTD PMID:747652 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Pla2g1b phospholipase A2 group IB multiple interactions
increases abundance
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [PLA2G1B protein results in increased abundance of Calcium]; [PLA2G1B protein results in increased abundance of Calcium] which results in increased expression of CXCL8 protein CTD PMID:15528384 NCBI chr12:46,879,346...46,890,234
Ensembl chr12:46,879,343...46,889,082
JBrowse link
G Pla2g2a phospholipase A2 group IIA increases uptake
multiple interactions
EXP PLA2G2A protein results in increased uptake of Calcium
BQ 788 inhibits the reaction [EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]]; EDN3 protein inhibits the reaction [PLA2G2A protein affects the uptake of Calcium]
CTD PMID:15695168 NCBI chr 5:157,282,650...157,285,295
Ensembl chr 5:157,282,669...157,285,328
JBrowse link
G Pla2g6 phospholipase A2 group VI increases activity
multiple interactions
EXP Calcium deficiency results in increased activity of PLA2G6 protein
6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium]; [Lipopolysaccharides results in increased expression of and results in increased activity of PLA2G6 protein] which results in increased susceptibility to Calcium
CTD PMID:17885217, PMID:21178110 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Plcg2 phospholipase C, gamma 2 multiple interactions ISO Calcium promotes the reaction [PLCG2 protein mutant form results in increased chemical synthesis of Inositol Phosphates]; Calcium promotes the reaction [PLCG2 protein results in increased chemical synthesis of Inositol Phosphates] CTD PMID:27542411 NCBI chr19:50,039,410...50,173,543
Ensembl chr19:50,045,020...50,173,220
JBrowse link
G Pnoc prepronociceptin decreases abundance EXP PNOC protein results in decreased abundance of Calcium CTD PMID:21039959 NCBI chr15:48,805,841...48,833,071
Ensembl chr15:48,805,228...48,833,285
JBrowse link
G Pon1 paraoxonase 1 increases activity
multiple interactions
ISO
EXP
Calcium results in increased activity of PON1 protein
[Calcium results in increased activity of PON1 protein] which affects the susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which affects the susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon
[Calcium co-treated with 1,2-dioleoyl-sn-glycero-3-phosphoglycerol] results in increased stability of PON1 protein; [Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Aldicarb; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to methylparaoxon; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to oxamyl; [Calcium results in increased activity of PON1 protein] which results in decreased susceptibility to Paraoxon; Calcium promotes the reaction [Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]]
CTD PMID:12871208, PMID:27132127 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon2 paraoxonase 2 affects abundance
multiple interactions
ISO PON2 gene polymorphism affects the abundance of Calcium
Calcium inhibits the reaction [lead acetate results in decreased activity of PON2 protein]
CTD PMID:16141008, PMID:22271317 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Pou6f1 POU class 6 homeobox 1 affects expression EXP Calcium affects the expression of POU6F1 mRNA CTD PMID:15913539 NCBI chr 7:142,201,614...142,225,256
Ensembl chr 7:142,204,036...142,210,738
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO [GW 7647 binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [Oleylethanolamide binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium]; [pirinixic acid binds to and results in increased activity of PPARA protein] affects the reaction [Glucose affects the abundance of Calcium] CTD PMID:19017711 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha affects expression EXP Calcium affects the expression of PPP1CA mRNA CTD PMID:15913539 NCBI chr 1:219,439,953...219,443,570
Ensembl chr 1:219,439,953...219,443,570
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta affects expression EXP Calcium affects the expression of PPP1CB mRNA CTD PMID:15913539 NCBI chr 6:23,548,507...23,581,136
Ensembl chr 6:23,549,317...23,581,052
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions EXP [Egtazic Acid co-treated with Calcium deficiency] results in increased expression of PPP1R15A mRNA CTD PMID:9878749 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha affects abundance
affects transport
ISO PPP2CA protein affects the abundance of Calcium
PPP2CA protein affects the transport of Calcium
CTD PMID:15247211 NCBI chr10:37,534,449...37,554,861
Ensembl chr10:37,535,871...37,554,664
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha multiple interactions
affects response to substance
ISO PPP3R1 gene mutant form inhibits the reaction [ATP2A2 protein affects the transport of Calcium]; PPP3R1 gene mutant form inhibits the reaction [SLC8A1 protein affects the transport of Calcium]
PPP3R1 gene mutant form affects the susceptibility to Calcium
CTD PMID:19700627 NCBI chr14:100,311,224...100,360,879
Ensembl chr14:100,311,173...100,360,879
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of PRDX6 mRNA CTD PMID:15913539 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Prkca protein kinase C, alpha multiple interactions
increases response to substance
EXP [Tretinoin co-treated with Calcium] results in increased activity of PRKCA protein
PRKCA protein results in increased susceptibility to Calcium
CTD PMID:12388232, PMID:16114872 NCBI chr10:96,186,509...96,585,168
Ensembl chr10:96,191,133...96,584,947
JBrowse link
G Prkcb protein kinase C, beta multiple interactions ISO Calcium inhibits the reaction [Chlordecone results in increased activity of PRKCB protein]; Calcium inhibits the reaction [Dicofol results in increased activity of PRKCB protein] CTD PMID:1724372 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkcd protein kinase C, delta affects expression EXP Calcium affects the expression of PRKCD mRNA CTD PMID:15913539 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions
increases phosphorylation
affects response to substance
ISO PRKCE protein affects the reaction [Oxygen deficiency results in increased abundance of Calcium]
Calcium results in increased phosphorylation of PRKCE protein
chelerythrine inhibits the reaction [Calcium results in increased phosphorylation of PRKCE protein]; PRKCE protein affects the reaction [F2RL1 protein promotes the reaction [[Capsaicin results in increased activity of TRPV1 protein] which results in increased abundance of Calcium]]
PRKCE protein affects the susceptibility to Calcium
CTD PMID:15242976, PMID:16793902, PMID:17087917, PMID:21562303 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prkcg protein kinase C, gamma multiple interactions ISO [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] CTD PMID:18652891 NCBI chr 1:64,407,098...64,433,698
Ensembl chr 1:64,407,114...64,433,636
JBrowse link
G Prkd1 protein kinase D1 multiple interactions ISO
EXP
PRKD1 promotes the reaction [Capsaicin results in increased uptake of Calcium]
PRKD1 mutant form inhibits the reaction [Capsaicin results in increased uptake of Calcium]
CTD PMID:15471852 NCBI chr 6:71,035,017...71,349,531
Ensembl chr 6:71,035,332...71,349,249
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 increases response to substance ISO PRKG1 protein results in increased susceptibility to Calcium CTD PMID:16533816 NCBI chr 1:248,982,039...250,300,952 JBrowse link
G Prl prolactin multiple interactions ISO Calcium inhibits the reaction [PRL protein binds to PRLR protein] CTD PMID:6197504 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Prlr prolactin receptor affects expression
multiple interactions
EXP
ISO
Calcium affects the expression of PRLR mRNA
Calcium inhibits the reaction [PRL protein binds to PRLR protein]
CTD PMID:6197504, PMID:15913539 NCBI chr 2:60,131,410...60,325,686
Ensembl chr 2:60,131,776...60,325,692
JBrowse link
G Prok2 prokineticin 2 multiple interactions
increases abundance
ISO PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] CTD PMID:16793879, PMID:17107623 NCBI chr 4:132,157,556...132,171,244
Ensembl chr 4:132,157,556...132,171,153
JBrowse link
G Prokr1 prokineticin receptor 1 multiple interactions ISO PROKR1 protein affects the reaction [Capsaicin results in increased abundance of Calcium]; PROKR1 protein affects the reaction [PROK2 protein results in increased abundance of Calcium] CTD PMID:16793879 NCBI chr 4:119,375,790...119,386,551
Ensembl chr 4:119,375,778...119,386,590
JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions EXP RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] CTD PMID:11297424 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 multiple interactions ISO PTGDR2 protein affects the abundance of and affects the localization of Calcium CTD PMID:16256979 NCBI chr 1:226,976,455...226,995,641
Ensembl chr 1:226,993,250...226,994,849
JBrowse link
G Ptger1 prostaglandin E receptor 1 multiple interactions
increases abundance
ISO 17-phenyltrinorprostaglandin E2 inhibits the reaction [PTGER1 protein results in increased abundance of Calcium] CTD PMID:11809688 NCBI chr19:24,799,422...24,803,373
Ensembl chr19:24,800,072...24,803,373
JBrowse link
G Ptger3 prostaglandin E receptor 3 multiple interactions EXP PTGER3 protein affects the reaction [Dinoprostone results in decreased transport of Calcium]; PTGER3 protein affects the reaction [ONO AE 248 results in decreased transport of Calcium] CTD PMID:12535167 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptgir prostaglandin I2 receptor multiple interactions ISO [cicaprost results in increased activity of PTGIR protein] which results in increased abundance of Calcium CTD PMID:11895442 NCBI chr 1:78,833,449...78,835,832
Ensembl chr 1:78,833,157...78,837,623
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 affects expression EXP Calcium affects the expression of PTGS1 mRNA CTD PMID:15913539 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
Calcium affects the reaction [bisperoxovanadium results in increased expression of PTGS2 mRNA]
Calcium deficiency inhibits the reaction [Serotonin results in increased expression of PTGS2 mRNA]
Calcium deficiency inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
CTD PMID:12493747, PMID:19782052, PMID:21262218 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth parathyroid hormone multiple interactions
increases stability
increases abundance
decreases abundance
affects metabolic processing
decreases expression
ISO
EXP
[Calcitriol co-treated with Calcium] results in decreased expression of PTH protein; [Cholecalciferol co-treated with Calcium] results in decreased expression of PTH protein
Calcium deficiency results in increased stability of PTH mRNA
Calcium affects the reaction [Aluminum Compounds results in decreased expression of PTH mRNA]; Calcium affects the reaction [Aluminum Compounds results in decreased secretion of PTH protein]; Calcium affects the reaction [Calcitriol results in decreased expression of PTH mRNA]; Calcium affects the reaction [Calcitriol results in decreased secretion of PTH protein]; Calcium deficiency inhibits the reaction [KHSRP protein binds to PTH 3' UTR]; Calcium deficiency promotes the reaction [HNRNPD protein binds to PTH 3' UTR]
PTH protein modified form results in increased abundance of Calcium
PTH protein results in decreased abundance of Calcium
PTH protein affects the metabolism of Calcium
Calcium results in decreased expression of PTH protein
CTD PMID:80633, PMID:6330156, PMID:15891005, PMID:16094769, PMID:16316325, PMID:17476578, PMID:18583400 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Pth1r parathyroid hormone 1 receptor affects expression EXP Calcium affects the expression of PTH1R mRNA CTD PMID:15913539 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions ISO
EXP
Calcium affects the reaction [(N)-methanocarba-2MeSADP results in increased phosphorylation of PTK2B protein]
Calcium affects the phosphorylation of and affects the activity of PTK2B protein
CTD PMID:16236484, PMID:16877402 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link
G Ptpn12 protein tyrosine phosphatase, non-receptor type 12 affects expression EXP Calcium affects the expression of PTPN12 mRNA CTD PMID:15913539 NCBI chr 4:10,631,129...10,702,390
Ensembl chr 4:10,631,073...10,702,386
JBrowse link
G Pygl glycogen phosphorylase L multiple interactions EXP [Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein; Calcium deficiency inhibits the reaction [Calcimycin results in increased activity of PYGL protein]; Glucose inhibits the reaction [[Phenylephrine co-treated with Calcium] results in increased activity of PYGL protein] CTD PMID:747652, PMID:6430282 NCBI chr 6:92,597,759...92,643,734
Ensembl chr 6:92,597,706...92,643,847
JBrowse link
G Rab7a RAB7A, member RAS oncogene family affects expression EXP Calcium affects the expression of RAB7 mRNA CTD PMID:15913539 NCBI chr 4:119,910,461...119,963,065
Ensembl chr 4:119,910,478...119,959,173
JBrowse link
G Ralgds ral guanine nucleotide dissociation stimulator affects expression EXP Calcium affects the expression of RALGDS mRNA CTD PMID:15913539 NCBI chr 3:7,090,134...7,130,548
Ensembl chr 3:7,109,920...7,130,548
JBrowse link
G Rap1a RAP1A, member of RAS oncogene family multiple interactions ISO Calcium promotes the reaction [ibandronic acid results in decreased prenylation of RAP1A protein] CTD PMID:18190680 NCBI chr 2:208,193,950...208,215,186
Ensembl chr 2:208,193,954...208,215,187
JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 multiple interactions ISO RAPGEF3 protein promotes the reaction [Benzo(a)pyrene results in increased transport of Calcium] CTD PMID:22167199 NCBI chr 7:139,232,263...139,254,668
Ensembl chr 7:139,232,251...139,254,551
JBrowse link
G Rbp1 retinol binding protein 1 affects expression EXP Calcium affects the expression of RBP1 mRNA CTD PMID:15913539 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842
JBrowse link
G Ren renin decreases secretion
multiple interactions
EXP Calcium results in decreased secretion of REN protein
[[Calcium results in increased activity of MYLK protein] which results in increased phosphorylation of MYL9 protein] which results in decreased secretion of REN protein; ML 7 inhibits the reaction [Calcium results in decreased secretion of REN protein]
CTD PMID:9618396 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Rgs4 regulator of G-protein signaling 4 multiple interactions EXP RGS4 protein inhibits the reaction [PTAFR protein affects the localization of and affects the abundance of Calcium] CTD PMID:11297424 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Rps3a ribosomal protein S3a affects expression EXP Calcium affects the expression of RPS3A mRNA CTD PMID:15913539 NCBI chr 2:185,440,477...185,444,846
Ensembl chr 2:185,440,291...185,444,897
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP
ISO
Calcium affects the reaction [[Phenylephrine results in increased activity of ADRA1A protein] which results in increased phosphorylation of RPS6KB1 protein]
[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in decreased expression of RPS6KB1 protein modified form]
CTD PMID:12935885, PMID:23680031 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Rptor regulatory associated protein of MTOR, complex 1 multiple interactions ISO [Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form; dorsomorphin inhibits the reaction [[Resveratrol results in increased abundance of Calcium] which results in increased activity of RPTOR protein modified form] CTD PMID:23680031 NCBI chr10:108,750,620...109,058,691
Ensembl chr10:108,750,620...109,058,691
JBrowse link
G Rraga Ras-related GTP binding A affects expression EXP Calcium affects the expression of RRAGA mRNA CTD PMID:15913539 NCBI chr 5:104,941,067...104,942,662
Ensembl chr 5:104,941,066...104,942,662
JBrowse link
G Ryr1 ryanodine receptor 1 multiple interactions
affects abundance
increases secretion
increases abundance
ISO
EXP
[Caffeine results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which affects the localization of Calcium; [chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium; [Halothane results in increased activity of RYR1 protein] which affects the localization of Calcium; [RYR1 protein co-treated with 2,3,6,2',3',6'-hexachlorobiphenyl] affects the susceptibility to Calcium; Calcium affects the folding of [CALM1 protein binds to RYR1 protein modified form]; Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Dantrolene inhibits the reaction [[chlorocresol results in increased activity of RYR1 protein] which results in increased transport of Calcium]; RYR1 protein polymorphism affects the reaction [Caffeine results in increased secretion of Calcium]; RYR1 protein polymorphism affects the reaction [chlorocresol results in increased secretion of Calcium]
RYR1 protein polymorphism affects the abundance of Calcium
RYR1 protein mutant form results in increased secretion of Calcium
RYR1 gene mutant form results in increased abundance of Calcium
Calcium affects the reaction [CALM1 protein binds to and affects the activity of RYR1 protein]; Calcium affects the reaction [CALM1 protein modified form binds to and affects the activity of RYR1 protein]
CTD PMID:15381065, PMID:15628869, PMID:16372898, PMID:17707769, PMID:18719443, PMID:18954145, PMID:19191329, PMID:21485675 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
JBrowse link
G Ryr2 ryanodine receptor 2 multiple interactions ISO
EXP
FKBP1A protein inhibits the reaction [Calcium results in increased activity of RYR2 protein]
Dantrolene inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Caffeine promotes the reaction [RYR2 protein results in increased secretion of Calcium]]; HOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]]
CTD PMID:12887973, PMID:17872463 NCBI chr17:65,533,998...65,955,606
Ensembl chr17:65,535,403...65,955,606
JBrowse link
G S100a13 S100 calcium binding protein A13 multiple interactions ISO [Calcium co-treated with Copper] binds to and affects the folding of S100A13 protein; Calcium binds to and affects the folding of S100A13 protein CTD PMID:16766622 NCBI chr 2:189,906,022...189,912,516
Ensembl chr 2:189,906,022...189,912,516
JBrowse link
G S100a6 S100 calcium binding protein A6 affects response to substance ISO S100A6 protein affects the susceptibility to Calcium CTD PMID:15068510 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions
affects binding
ISO [Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein]
Calcium binds to [S100A8 protein binds to S100A9 protein]
CTD PMID:17050004 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 affects binding
multiple interactions
ISO Calcium binds to [S100A8 protein binds to S100A9 protein]
[Zinc co-treated with Calcium] binds to [S100A8 protein binds to S100A9 protein]
CTD PMID:17050004 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G S100g S100 calcium binding protein G affects expression EXP Calcium affects the expression of S100G mRNA CTD PMID:15913539 NCBI chr  X:33,442,820...33,445,714
Ensembl chr  X:33,443,186...33,445,709
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 increases expression ISO Calcium results in increased expression of SCGB1A1 mRNA; Calcium results in increased expression of SCGB1A1 protein CTD PMID:16237193 NCBI chr 1:225,279,698...225,283,246
Ensembl chr 1:225,279,676...225,283,326
JBrowse link
G Sct secretin increases abundance ISO SCT protein results in increased abundance of Calcium CTD PMID:1220513 NCBI chr 1:214,264,865...214,277,437
Ensembl chr 1:214,264,754...214,265,668
JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 multiple interactions
increases transport
ISO [HSPA5 protein binds to SEC61A1 protein] which results in decreased transport of Calcium; [SEC61A1 protein results in increased transport of Calcium] which results in increased susceptibility to Thapsigargin; DNAJB11 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium]; DNAJC3 protein inhibits the reaction [SEC61A1 protein results in increased transport of Calcium] CTD PMID:26085089 NCBI chr 4:120,453,577...120,467,932
Ensembl chr 4:120,453,581...120,467,932
JBrowse link
G Selenot selenoprotein T multiple interactions
affects abundance
EXP Calcium affects the reaction [ADCYAP1 protein results in increased expression of SELENOT mRNA]; SELENOT protein affects the reaction [ADCYAP1 protein results in increased abundance of Calcium]; Thapsigargin promotes the reaction [SELENOT protein affects the abundance of Calcium] CTD PMID:18198219 NCBI chr 2:148,765,412...148,781,080
Ensembl chr 2:148,765,412...148,780,276
JBrowse link
G Serpine1 serpin family E member 1 increases stability ISO Calcium results in increased stability of SERPINE1 protein CTD PMID:21280127, PMID:21280128 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Slc12a5 solute carrier family 12 member 5 multiple interactions EXP Calcium affects the reaction [Zinc results in increased activity of SLC12A5 protein] CTD PMID:22441041 NCBI chr 3:161,433,303...161,465,078
Ensembl chr 3:161,425,988...161,462,879
JBrowse link
G Slc23a2 solute carrier family 23 member 2 decreases expression
multiple interactions
increases expression
ISO Calcium deficiency results in decreased expression of SLC23A2 mRNA
Foscarnet inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]; Nifedipine inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]
Calcium results in increased expression of SLC23A2 mRNA; Calcium results in increased expression of SLC23A2 protein
CTD PMID:12788230 NCBI chr 3:124,632,491...124,842,225
Ensembl chr 3:124,632,492...124,724,252
JBrowse link
G Slc24a2 solute carrier family 24 member 2 increases uptake EXP SLC24A2 protein results in increased uptake of Calcium CTD PMID:14660663 NCBI chr 5:105,336,287...105,579,959
Ensembl chr 5:105,336,262...105,582,375
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions EXP Calcium deficiency inhibits the reaction [2,3-dinitrophenol results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [Arsenates results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [Azides results in increased activity of SLC2A1 protein]; Calcium deficiency inhibits the reaction [INS1 protein results in increased activity of SLC2A1 protein] CTD PMID:10970766 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions EXP [CACNA1D protein results in increased uptake of Calcium] which affects the localization of SLC2A2 protein CTD PMID:17272349 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a4 solute carrier family 2 member 4 multiple interactions EXP [[Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein] which results in increased uptake of Glucose; [Chloroquine results in increased abundance of Calcium] which affects the localization of SLC2A4 protein CTD PMID:27160165 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions EXP [Calcium co-treated with Calcitriol] affects the expression of SLC30A1 mRNA CTD PMID:15913539 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc5a1 solute carrier family 5 member 1 multiple interactions EXP SLC5A1 protein affects the reaction [CACNA1D protein results in increased uptake of Calcium] CTD PMID:17272349 NCBI chr14:82,910,448...82,975,303
Ensembl chr14:82,909,981...82,975,263
JBrowse link
G Slc8a1 solute carrier family 8 member A1 multiple interactions
increases transport
ISO
EXP
Calcium inhibits the reaction [SLC8A1 protein results in increased uptake of Nickel]
PPP3R1 gene mutant form inhibits the reaction [SLC8A1 protein affects the transport of Calcium]
SLC8A1 protein results in increased transport of Calcium
2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonate inhibits the reaction [SLC8A1 protein results in increased transport of Calcium]
CTD PMID:10329968, PMID:18822394, PMID:19700627 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Slc8a2 solute carrier family 8 member A2 increases uptake EXP SLC8A2 protein results in increased uptake of Calcium CTD PMID:14660663 NCBI chr 1:78,029,555...78,054,042
Ensembl chr 1:78,025,995...78,060,111
JBrowse link
G Slc8a3 solute carrier family 8 member A3 increases transport
increases uptake
EXP SLC8A3 protein results in increased transport of Calcium
SLC8A3 protein results in increased uptake of Calcium
CTD PMID:14660663, PMID:17585341 NCBI chr 6:104,889,500...105,099,408
Ensembl chr 6:104,891,376...105,097,054
JBrowse link
G Slc9a1 solute carrier family 9 member A1 multiple interactions EXP 3-methylsulfonyl-4-piperidinobenzoyl guanidine inhibits the reaction [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium]; [[Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium] which results in increased expression of ATP2A2 protein; [Phenylephrine results in increased activity of SLC9A1 protein] which results in increased transport of Calcium