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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:coenzyme
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Accession:CHEBI:23354 term browser browse the term
Definition:A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons.
Synonyms:related_synonym: coenzymes


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5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avp arginine vasopressin multiple interactions EXP pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of AVP protein] CTD PMID:11102496 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Fn1 fibronectin 1 decreases expression ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid results in decreased expression of FN1 mRNA CTD PMID:18210741 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Il6 interleukin 6 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Silicon Dioxide analog results in increased expression of IL6 protein] CTD PMID:24793913 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [NOX1 protein promotes the reaction [glycylphenylalanine 2-naphthylamide results in increased export of Calcium]] CTD PMID:24912985 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide multiple interactions EXP pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of OXT protein]; pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased secretion of OXT protein] CTD PMID:11102496 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [Adenosine Triphosphate results in increased activity of P2RX7 protein] CTD PMID:21638035 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein] CTD PMID:22253048 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
5,6,7,8-tetrahydrobiopterin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP sapropterin inhibits the reaction [Fructose results in decreased expression of ADIPOQ mRNA]; sapropterin inhibits the reaction [Fructose results in decreased expression of ADIPOQ protein] CTD PMID:17098227 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO APP gene mutant form results in increased oxidation of and results in decreased abundance of sapropterin; GW 501516 inhibits the reaction [APP gene mutant form results in increased oxidation of and results in decreased abundance of sapropterin] CTD PMID:22886847 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO sapropterin inhibits the reaction [Methotrexate results in increased expression of CDKN1A protein] CTD PMID:22183962 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Epo erythropoietin multiple interactions
increases abundance
ISO EPO protein inhibits the reaction [GCH1 mutant form results in decreased abundance of sapropterin]
EPO protein results in increased abundance of sapropterin
EPO protein inhibits the reaction [[GCH1 gene mutant form results in increased oxidation of sapropterin] which results in increased chemical synthesis of 7,8-dihydrobiopterin]; EPO protein inhibits the reaction [[NOS3 protein co-treated with sapropterin deficiency] results in increased chemical synthesis of Superoxides]; EPO protein inhibits the reaction [HPH1 gene mutant form results in increased oxidation of sapropterin]
CTD PMID:25041251, PMID:25490417 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Gch1 GTP cyclohydrolase 1 decreases abundance
affects abundance
multiple interactions
increases chemical synthesis
ISO GCH1 mutant form results in decreased abundance of sapropterin
GCH1 protein affects the abundance of sapropterin
[GCH1 gene mutant form results in increased oxidation of sapropterin] which results in increased chemical synthesis of 7,8-dihydrobiopterin; [resveratrol results in increased expression of GCH1 mRNA] which results in increased abundance of sapropterin; EPO protein inhibits the reaction [[GCH1 gene mutant form results in increased oxidation of sapropterin] which results in increased chemical synthesis of 7,8-dihydrobiopterin]; GCH1 gene mutant form results in increased oxidation of and results in decreased abundance of sapropterin
GCH1 protein results in increased chemical synthesis of sapropterin
EPO protein inhibits the reaction [GCH1 mutant form results in decreased abundance of sapropterin]
CTD PMID:14551046, PMID:20610621, PMID:21963838, PMID:25041251, PMID:25490417 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Nos3 nitric oxide synthase 3 increases activity
multiple interactions
ISO sapropterin results in increased activity of NOS3 protein
sapropterin deficiency inhibits the reaction [NOS3 protein results in increased abundance of Superoxides]; sapropterin deficiency promotes the reaction [NOS3 protein results in increased abundance of Superoxides]
[NOS3 protein co-treated with sapropterin deficiency] results in increased chemical synthesis of Superoxides; EPO protein inhibits the reaction [[NOS3 protein co-treated with sapropterin deficiency] results in increased chemical synthesis of Superoxides]
CTD PMID:19011239, PMID:23753407, PMID:25490417 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Sct secretin increases abundance ISO SCT protein results in increased abundance of sapropterin CTD PMID:16168596 NCBI chr 1:214,264,865...214,277,437
Ensembl chr 1:214,264,754...214,265,668
JBrowse link
G Snca synuclein alpha increases abundance ISO SNCA mutant form results in increased abundance of sapropterin CTD PMID:24148766 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO sapropterin inhibits the reaction [Methotrexate results in increased expression of TP53 protein] CTD PMID:22183962 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
acetoacetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 affects binding ISO acetoacetyl CoA binds to HSD17B2 protein CTD PMID:25526675 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
acetyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acly ATP citrate lyase increases abundance ISO ACLY protein results in increased abundance of Acetyl Coenzyme A CTD PMID:28077572 NCBI chr10:88,392,248...88,442,845
Ensembl chr10:88,392,248...88,442,845
JBrowse link
G App amyloid beta precursor protein affects localization
increases secretion
multiple interactions
ISO APP protein affects the localization of Acetyl Coenzyme A
Acetyl Coenzyme A results in increased secretion of APP protein modified form
Acetyl Coenzyme A inhibits the reaction [Hydrogen Peroxide results in decreased secretion of APP protein modified form]
IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A]
CTD PMID:16122837, PMID:22906069 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Crat carnitine O-acetyltransferase decreases activity EXP Acetyl Coenzyme A deficiency results in decreased activity of CRAT protein CTD PMID:8075222 NCBI chr 3:8,967,984...8,981,959
Ensembl chr 3:8,968,417...8,981,362
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor decreases abundance
multiple interactions
ISO ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A
3-Hydroxybutyric Acid inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [ERCC6 gene mutant form results in decreased abundance of Acetyl Coenzyme A]
CTD PMID:25440059 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO IL1B protein affects the reaction [APP protein affects the localization of Acetyl Coenzyme A] CTD PMID:16122837 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Kat2b lysine acetyltransferase 2B affects binding ISO Acetyl Coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:4,440,982...4,492,949 JBrowse link
G Metrnl meteorin-like, glial cell differentiation regulator multiple interactions ISO METRNL protein inhibits the reaction [Dietary Fats results in decreased abundance of Acetyl Coenzyme A] CTD PMID:30213948 NCBI chr10:110,893,261...110,907,256
Ensembl chr10:110,893,232...110,907,243
JBrowse link
G Nat1 N-acetyltransferase 1 multiple interactions
affects binding
ISO [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone; Acetyl Coenzyme A inhibits the reaction [Cyanamide results in decreased activity of NAT1 protein]; Acetyl Coenzyme A inhibits the reaction [Iodoacetamide results in decreased activity of NAT1 protein]
Acetyl Coenzyme A binds to NAT1 protein
CTD PMID:20545351, PMID:22835378 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
JBrowse link
G Nat2 N-acetyltransferase 2 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[SULT1A2 protein co-treated with Phosphoadenosine Phosphosulfate] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone] CTD PMID:20545351 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [NAT2 protein co-treated with Acetyl Coenzyme A] promotes the reaction [[NQO1 protein co-treated with NADP] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone]; [NQO1 protein co-treated with NADP co-treated with Acetyl Coenzyme A co-treated with NAT1 protein] results in increased activity of and results in increased reduction of 3-nitrobenzanthrone CTD PMID:20545351 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
acryloyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Echs1 enoyl-CoA hydratase, short chain 1 increases abundance ISO ECHS1 gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Hibch 3-hydroxyisobutyryl-CoA hydrolase increases abundance ISO HIBCH gene mutant form results in increased abundance of acryloyl-coenzyme A CTD PMID:25125611 NCBI chr 9:53,446,185...53,526,727
Ensembl chr 9:53,446,194...53,526,728
JBrowse link
arachidonoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
biopterin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects abundance
multiple interactions
ISO ABCC1 protein affects the abundance of Biopterin analog
ABCC1 protein affects the reaction [AGT protein results in decreased abundance of Biopterin analog]
CTD PMID:17272743 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Agt angiotensinogen multiple interactions
decreases abundance
ISO ABCC1 protein affects the reaction [AGT protein results in decreased abundance of Biopterin analog] CTD PMID:17272743 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
biotin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP [Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in decreased phosphorylation of AKT1 protein]; [Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased cleavage of AKT1 protein]; Biotin inhibits the reaction [Aluminum Chloride results in decreased phosphorylation of AKT1 protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased cleavage of AKT1 protein] CTD PMID:32383521 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G App amyloid beta precursor protein multiple interactions EXP [Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of APP protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of APP protein] CTD PMID:32383521 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 decreases expression ISO Biotin results in decreased expression of CXCL11 mRNA CTD PMID:15219929 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
increases expression
ISO Biotin results in increased expression of and results in increased activity of CYP1B1 protein
Biotin results in increased expression of CYP1B1 mRNA
CTD PMID:15219929, PMID:15333708 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO Biotin inhibits the reaction [Cycloheximide results in increased degradation of CYP2E1 protein] CTD PMID:9143349 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions ISO [Chromium co-treated with Biotin] results in decreased expression of HBA1 protein modified form; [chromium tripicolinate co-treated with Biotin] results in decreased expression of HBA1 protein modified form CTD PMID:17684468 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Herc4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 increases expression ISO Biotin results in increased expression of HERC4 mRNA CTD PMID:15219929 NCBI chr20:26,755,948...26,831,267
Ensembl chr20:26,755,911...26,830,931
JBrowse link
G Hira histone cell cycle regulator decreases expression ISO Biotin results in decreased expression of HIRA mRNA CTD PMID:15219929 NCBI chr11:86,168,196...86,276,430
Ensembl chr11:86,168,196...86,276,430
JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 increases expression ISO Biotin results in increased expression of IGHG1 mRNA CTD PMID:15219929 NCBI chr 6:139,140,572...139,784,388
Ensembl chr 6:139,140,679...139,142,218
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein] CTD PMID:32383521 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions EXP [Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of IL6 protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of IL6 protein] CTD PMID:32383521 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP [Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride affects the phosphorylation of IRS1 protein]; Biotin inhibits the reaction [Aluminum Chloride affects the phosphorylation of IRS1 protein] CTD PMID:32383521 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 decreases expression ISO Biotin results in decreased expression of LAMP1 mRNA CTD PMID:15219929 NCBI chr16:81,689,576...81,714,341
Ensembl chr16:81,689,335...81,714,419
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Biotin results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Sele selectin E affects binding ISO [Acetylglucosamine analog binds to Biotin] which binds to SELE protein CTD PMID:12191509 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Sell selectin L affects binding EXP [Acetylglucosamine analog binds to Biotin] which binds to SELL protein CTD PMID:12191509 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Selp selectin P affects binding ISO [Acetylglucosamine analog binds to Biotin] which binds to SELP protein CTD PMID:12191509 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Slc5a6 solute carrier family 5 member 6 affects expression
increases transport
multiple interactions
increases uptake
ISO
EXP
Biotin affects the expression of SLC5A6 mRNA; Biotin affects the expression of SLC5A6 protein
SLC5A6 results in increased transport of Biotin
Sodium affects the reaction [SLC5A6 results in increased transport of Biotin]; Thioctic Acid inhibits the reaction [SLC5A6 results in increased transport of Biotin]
2,4-Dinitrophenol inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; 4-Chloromercuribenzenesulfonate inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Azides inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; calmidazolium inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; chelerythrine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Gramicidin inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Iodoacetates inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Ouabain inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Probenecid inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Sodium affects the reaction [SLC5A6 results in increased transport of Biotin]; Sodium promotes the reaction [SLC5A6 protein results in increased transport of Biotin]; Staurosporine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]; Tetradecanoylphorbol Acetate promotes the reaction [SLC5A6 protein results in increased transport of Biotin]; Trifluoperazine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin]
SLC5A6 results in increased uptake of Biotin
SLC5A6 protein results in increased transport of Biotin; SLC5A6 results in increased transport of Biotin
CTD PMID:9516450, PMID:10329687, PMID:10516089, PMID:12646417, PMID:15561972 NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116
JBrowse link
G Tmprss15 transmembrane serine protease 15 increases expression ISO Biotin results in increased expression of TMPRSS15 mRNA CTD PMID:15219929 NCBI chr11:17,561,591...17,684,903
Ensembl chr11:17,561,596...17,684,903
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP [Biotin co-treated with coenzyme Q10] inhibits the reaction [Aluminum Chloride results in increased expression of TNF protein]; Biotin inhibits the reaction [Aluminum Chloride results in increased expression of TNF protein] CTD PMID:32383521 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tpr translocated promoter region, nuclear basket protein increases expression ISO Biotin results in increased expression of TPR mRNA CTD PMID:15219929 NCBI chr13:67,611,685...67,672,833
Ensembl chr13:67,611,708...67,672,827
JBrowse link
butyryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kat2b lysine acetyltransferase 2B affects binding ISO butyryl-coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:4,440,982...4,492,949 JBrowse link
cobamamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO cobamamide inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
coenzyme A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot8 acyl-CoA thioesterase 8 affects hydrolysis ISO ACOT8 protein affects the hydrolysis of Coenzyme A analog CTD PMID:16141203 NCBI chr 3:161,260,837...161,272,495
Ensembl chr 3:161,259,735...161,272,460
JBrowse link
G Kat2b lysine acetyltransferase 2B affects binding ISO Coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:4,440,982...4,492,949 JBrowse link
decanoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsdl2 hydroxysteroid dehydrogenase like 2 multiple interactions ISO [decanoyl-coenzyme A co-treated with NADP] binds to HSDL2 protein CTD PMID:25526675 NCBI chr 5:76,812,881...76,848,853
Ensembl chr 5:76,812,931...76,848,101
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [decanoyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:79,601,937...79,630,547
Ensembl chr 9:79,601,901...79,630,536
JBrowse link
FMN term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance
ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of Flavin Mononucleotide] CTD PMID:27469509 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Rfk riboflavin kinase increases abundance ISO RFK protein results in increased abundance of Flavin Mononucleotide CTD PMID:21308351 NCBI chr 1:236,494,221...236,501,733
Ensembl chr 1:236,494,221...236,501,733
JBrowse link
G Slc52a3 solute carrier family 52 member 3 multiple interactions EXP Flavin Mononucleotide inhibits the reaction [SLC52A3 protein results in increased transport of Riboflavin] CTD PMID:19122205 NCBI chr 3:147,503,266...147,517,935
Ensembl chr 3:147,511,406...147,516,455
JBrowse link
glutaryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acot4 acyl-CoA thioesterase 4 affects hydrolysis ISO ACOT4 protein affects the hydrolysis of glutaryl-coenzyme A CTD PMID:16141203 NCBI chr 6:107,517,668...107,522,952
Ensembl chr 6:107,517,668...107,522,952
JBrowse link
G Acot8 acyl-CoA thioesterase 8 affects hydrolysis ISO ACOT8 protein affects the hydrolysis of glutaryl-coenzyme A CTD PMID:16141203 NCBI chr 3:161,260,837...161,272,495
Ensembl chr 3:161,259,735...161,272,460
JBrowse link
hexanoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pecr peroxisomal trans-2-enoyl-CoA reductase multiple interactions ISO [hexanoyl-coenzyme A co-treated with NADP] binds to PECR protein CTD PMID:25526675 NCBI chr 9:79,601,937...79,630,547
Ensembl chr 9:79,601,901...79,630,536
JBrowse link
isobutyryl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kat2b lysine acetyltransferase 2B affects binding ISO isobutyryl-coenzyme A binds to KAT2B protein CTD PMID:28077572 NCBI chr 9:4,440,982...4,492,949 JBrowse link
L-ascorbic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 decreases expression ISO Ascorbic Acid results in decreased expression of AARS1 mRNA CTD PMID:19197388 NCBI chr19:43,193,264...43,215,281
Ensembl chr19:43,193,257...43,215,281
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mRNA; [Bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [diazepinylbenzoic acid co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mRNA; [LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ABCA1 mRNA; [Rosiglitazone co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [TO-901317 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA] CTD PMID:17639512, PMID:25932594 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO
EXP
Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of ABCB1A mRNA]
CTD PMID:22914566, PMID:31739238 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA] CTD PMID:22914566 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO
EXP
Ascorbic Acid inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]]; Ascorbic Acid promotes the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 mRNA]; Ascorbic Acid inhibits the reaction [Fructose results in decreased expression of ABCC2 protein]
CTD PMID:19326901, PMID:22914566, PMID:31005848 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Acan aggrecan multiple interactions ISO [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]] CTD PMID:26526931 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions ISO Ascorbic Acid inhibits the reaction [epigallocatechin gallate results in decreased activity of ACE protein] CTD PMID:28544013 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ACE2 mRNA CTD PMID:17639512 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Ache acetylcholinesterase decreases activity
multiple interactions
increases activity
ISO
EXP
Ascorbic Acid results in decreased activity of ACHE protein
[Dexamethasone co-treated with Ascorbic Acid] results in increased expression of ACHE mRNA; [Dexamethasone co-treated with Ascorbic Acid] results in increased expression of and results in increased activity of ACHE protein; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of ACHE protein]; Ascorbic Acid inhibits the reaction [Scopolamine results in decreased activity of ACHE protein]
Ascorbic Acid inhibits the reaction [Glucose results in decreased activity of ACHE protein]
Ascorbic Acid results in increased activity of ACHE protein
[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of ACHE protein]
CTD PMID:11814146, PMID:16248992, PMID:16822217, PMID:19703495, PMID:20663516, PMID:23619517, PMID:26163454, PMID:27019979 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 decreases expression EXP Ascorbic Acid results in decreased expression of ACSL4 mRNA CTD PMID:15372504 NCBI chr  X:113,596,247...113,660,024
Ensembl chr  X:113,596,239...113,659,944
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP
ISO
[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of ACTA2 protein
[Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of ACTA2 mRNA; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of ACTA2 protein; [Mercaptoethanol co-treated with Ascorbic Acid] results in increased expression of ACTA2 protein; Ascorbic Acid promotes the reaction [Quartz results in increased expression of ACTA2 mRNA]
CTD PMID:7593635, PMID:17053324, PMID:18607632, PMID:27381660 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adcy6 adenylate cyclase 6 decreases expression ISO Ascorbic Acid results in decreased expression of ADCY6 mRNA CTD PMID:17303424 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 decreases expression EXP Ascorbic Acid results in decreased expression of ADGRL1 mRNA CTD PMID:15372504 NCBI chr19:25,029,037...25,069,146
Ensembl chr19:25,029,037...25,069,142
JBrowse link
G Ago2 argonaute RISC catalytic component 2 decreases expression EXP Ascorbic Acid results in decreased expression of AGO2 mRNA CTD PMID:15372504 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Agt angiotensinogen multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [AGT protein modified form results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [AGT protein modified form results in increased expression of TIMP1 protein]
[Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]; [Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [pyruvamide binds to AGT protein modified form]]; Ascorbic Acid promotes the reaction [linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form]; Losartan inhibits the reaction [[AGT protein modified form co-treated with Ascorbic Acid co-treated with Copper Sulfate] results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]]; Losartan inhibits the reaction [[AGT protein modified form co-treated with Ascorbic Acid co-treated with Copper Sulfate] results in increased chemical synthesis of [pyruvamide binds to AGT protein modified form]]
CTD PMID:20881940, PMID:26111765, PMID:31144504 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ak4 adenylate kinase 4 decreases expression ISO Ascorbic Acid results in decreased expression of AK4 mRNA CTD PMID:15305145 NCBI chr 5:120,250,318...120,309,153
Ensembl chr 5:120,250,616...120,305,897
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases reduction ISO Ascorbic Acid results in increased reduction of AKR1B1 protein modified form CTD PMID:19061876 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Ascorbic Acid results in increased expression of AKR1B10 mRNA CTD PMID:26198647 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Ascorbic Acid results in increased expression of AKR1C2 mRNA CTD PMID:26198647 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of AKT1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of AKT1 protein] CTD PMID:21262251, PMID:21911000 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 affects expression ISO Ascorbic Acid affects the expression of AKT2 mRNA CTD PMID:30597948 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 multiple interactions ISO [Ascorbic Acid co-treated with 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid] inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein]; Ascorbic Acid inhibits the reaction [Griseofulvin results in increased activity of ALAS1 protein] CTD PMID:24523661 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO ALDH2 protein affects the reaction [Ascorbic Acid deficiency results in decreased susceptibility to Nitroglycerin] CTD PMID:23194305 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alpi alkaline phosphatase, intestinal multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ALPI mRNA CTD PMID:17639512 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions
increases expression
ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA]
Ascorbic Acid results in increased expression of ALPL mRNA
CTD PMID:26424790, PMID:26492236, PMID:28105418 NCBI chr 5:156,086,496...156,141,513
Ensembl chr 5:156,086,497...156,141,537
JBrowse link
G Anpep alanyl aminopeptidase, membrane multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of ANPEP mRNA CTD PMID:17639512 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Anxa1 annexin A1 multiple interactions
increases expression
ISO
EXP
[Quercetin co-treated with Ascorbic Acid] results in increased expression of ANXA1 mRNA
Ascorbic Acid results in increased expression of ANXA1 mRNA
CTD PMID:15372504, PMID:17639512 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa5 annexin A5 multiple interactions
increases expression
ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ANXA5 mRNA
Ascorbic Acid results in increased expression of ANXA5 mRNA
Ascorbic Acid results in increased expression of ANXA5 protein
CTD PMID:15372504, PMID:17917374, PMID:19224539 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Apoa1 apolipoprotein A1 decreases expression
decreases activity
ISO
EXP
Ascorbic Acid results in decreased expression of APOA1 mRNA; Ascorbic Acid results in decreased expression of APOA1 protein
Ascorbic Acid results in decreased activity of APOA1 promoter
CTD PMID:16423621 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apob apolipoprotein B multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOB mRNA; Ascorbic Acid promotes the reaction [Flavonoids inhibits the reaction [Copper results in increased oxidation of APOB protein]]; Ascorbic Acid promotes the reaction [Quercetin inhibits the reaction [Copper results in increased oxidation of APOB protein]] CTD PMID:17475462, PMID:17639512 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Apoe apolipoprotein E increases expression EXP Ascorbic Acid results in increased expression of APOE mRNA CTD PMID:15372504 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Apom apolipoprotein M multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of APOM mRNA CTD PMID:17639512 NCBI chr20:5,120,473...5,123,073
Ensembl chr20:5,120,474...5,123,073
JBrowse link
G App amyloid beta precursor protein multiple interactions
decreases abundance
increases oxidation
EXP
ISO
Ascorbic Acid inhibits the reaction [APP protein modified form results in increased abundance of Reactive Oxygen Species]; resveratrol inhibits the reaction [APP protein modified form results in decreased abundance of Ascorbic Acid]
APP protein modified form results in increased oxidation of Ascorbic Acid
[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; [[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide; [[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide; [[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines; [APP protein modified form binds to Copper] which results in increased oxidation of Ascorbic Acid; [APP protein modified form inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide]] which results in increased chemical synthesis of 4-hydroxy-2-nonenal; APP protein inhibits the reaction [Copper results in increased oxidation of Ascorbic Acid]; APP protein modified form inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide]; Copper promotes the reaction [APP protein modified form results in increased oxidation of Ascorbic Acid]; Deferoxamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Edetic Acid inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]; Penicillamine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of phosphatidylcholine hydroperoxide] which results in increased chemical synthesis of 4-hydroxy-2-nonenal]; Trientine inhibits the reaction [[[[APP protein modified form binds to Copper] which co-treated with Ascorbic Acid] results in increased oxidation of Phosphatidylcholines] which results in increased chemical synthesis of phosphatidylcholine hydroperoxide]
CTD PMID:15030205, PMID:17964426, PMID:24276282, PMID:25654502 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of AQP3 mRNA CTD PMID:17639512 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO Ascorbic Acid results in increased expression of ARHGDIA mRNA CTD PMID:22139585 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta multiple interactions
increases expression
ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of ARHGDIB mRNA
Ascorbic Acid results in increased expression of ARHGDIB protein
CTD PMID:17639512, PMID:22139585 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arpc5 actin related protein 2/3 complex, subunit 5 increases expression ISO Ascorbic Acid results in increased expression of ARPC5 mRNA; Ascorbic Acid results in increased expression of ARPC5 protein CTD PMID:22139585 NCBI chr13:70,174,970...70,183,879
Ensembl chr13:70,174,936...70,183,879
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Ascorbic Acid results in decreased expression of ASNS mRNA CTD PMID:19197388 NCBI chr 4:33,742,876...33,761,106
Ensembl chr 4:33,743,364...33,761,163
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of ATAD2 mRNA CTD PMID:26424790 NCBI chr 7:97,984,754...98,027,379
Ensembl chr 7:97,984,862...98,026,052
JBrowse link
G Atad2b ATPase family, AAA domain containing 2B multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ATAD2B mRNA CTD PMID:26424790 NCBI chr 6:28,998,080...29,066,850
Ensembl chr 6:29,012,007...29,163,134
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of ATF3 mRNA CTD PMID:17639512 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNA
Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of ATM protein modified form]
CTD PMID:17917374, PMID:25977998 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression ISO Ascorbic Acid results in increased expression of ATP5B protein CTD PMID:22139585 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression ISO Ascorbic Acid results in increased expression of ATP6V1A mRNA CTD PMID:22139585 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Aurkb aurora kinase B multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of AURKB mRNA CTD PMID:17639512 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Auts2 activator of transcription and developmental regulator AUTS2 increases expression ISO Ascorbic Acid results in increased expression of AUTS2 mRNA CTD PMID:25555879 NCBI chr12:27,155,362...28,252,752
Ensembl chr12:28,212,333...28,251,816
JBrowse link
G B2m beta-2 microglobulin increases expression EXP Ascorbic Acid results in increased expression of B2M mRNA CTD PMID:15372504 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAD protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased phosphorylation of BAD protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAD protein]
[juglone co-treated with Ascorbic Acid] results in increased expression of BAD protein
CTD PMID:21262251, PMID:29992683 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BAK1 protein CTD PMID:24126434 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
[Arsenic Trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in increased expression of BAX protein; [juglone co-treated with Ascorbic Acid] results in increased expression of BAX protein; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of BAX mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased expression of BAX protein]
Ascorbic Acid inhibits the reaction [glycidamide results in increased expression of BAX mRNA]
Ascorbic Acid inhibits the reaction [Humic Substances results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of BAX protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]
CTD PMID:17166419, PMID:17959157, PMID:18683188, PMID:18758938, PMID:21262251, PMID:22245848, PMID:24126434, PMID:29992683, PMID:32632975 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein] CTD PMID:20530418 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO [Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein; Hexachlorocyclohexane inhibits the reaction [[Resveratrol co-treated with Ascorbic Acid co-treated with Thioctic Acid co-treated with Vitamin E] results in increased activity of BCHE protein] CTD PMID:20663516 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
increases abundance
ISO
EXP
Ascorbic Acid results in decreased expression of BCL2 mRNA
Ascorbic Acid inhibits the reaction [glycidamide results in decreased expression of BCL2 mRNA]
[arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Ascorbic Acid co-treated with Quartz] results in increased expression of BCL2 mRNA; Ascorbic Acid inhibits the reaction [deoxynivalenol results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of BCL2 mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of BCL2 protein]
Ascorbic Acid inhibits the reaction [Humic Substances results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ascorbic Acid promotes the reaction [lead acetate results in increased expression of BCL2 protein]
BCL2 protein results in increased abundance of Ascorbic Acid
CTD PMID:15449323, PMID:17166419, PMID:17959157, PMID:18683188, PMID:18758938, PMID:21262251, PMID:21919647, PMID:22245848, PMID:24126434, PMID:27381660, PMID:32632975 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of BCL2L1 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein] CTD PMID:18758938, PMID:21262251 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l14 BCL2 like 14 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of BCL2L14 mRNA CTD PMID:17639512 NCBI chr 4:168,139,964...168,183,726
Ensembl chr 4:168,142,271...168,183,096
JBrowse link
G Bcl2l2 Bcl2-like 2 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of BCL2L2 mRNA CTD PMID:17917374 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Bco1 beta-carotene oxygenase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]] CTD PMID:9526112 NCBI chr19:49,637,059...49,673,577
Ensembl chr19:49,637,016...49,673,808
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression ISO Ascorbic Acid results in increased expression of BDNF mRNA CTD PMID:15305145 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions
affects binding
ISO
EXP
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Copper] affects the cleavage of BGLAP3 protein; [Ascorbic Acid co-treated with Dexamethasone] results in increased expression of BGLAP mRNA; [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of BGLAP protein; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP mRNA; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of BGLAP protein; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP protein; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BGLAP protein]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of BGLAP mRNA]]
BGLAP3 protein binds to Ascorbic Acid
CTD PMID:11396734, PMID:12510807, PMID:17692823, PMID:25932594, PMID:26492236, PMID:27028516, PMID:31935364, PMID:32473317 NCBI chr 2:187,741,770...187,748,445
Ensembl chr 2:187,741,770...187,742,747
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [juglone co-treated with Ascorbic Acid] affects the expression of BID protein CTD PMID:29992683 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of BIRC3 mRNA CTD PMID:17639512 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Ascorbic Acid results in decreased expression of BIRC5 mRNA CTD PMID:21919647 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Bmp1 bone morphogenetic protein 1 multiple interactions EXP [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP1 mRNA CTD PMID:15994055 NCBI chr15:52,166,401...52,210,786
Ensembl chr15:52,166,401...52,210,746
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions EXP
ISO
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]]
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]
CTD PMID:15994055, PMID:26492236, PMID:27387537 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp3 bone morphogenetic protein 3 multiple interactions EXP [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP3 mRNA CTD PMID:15994055 NCBI chr14:12,362,912...12,387,572
Ensembl chr14:12,359,363...12,387,102
JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions EXP [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP7 mRNA CTD PMID:15994055 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A multiple interactions EXP [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]] CTD PMID:27387537 NCBI chr16:10,758,278...10,852,170
Ensembl chr16:10,758,527...10,802,512
JBrowse link
G Bmpr1b bone morphogenetic protein receptor type 1B increases expression ISO Ascorbic Acid results in increased expression of BMPR1B mRNA CTD PMID:15305145 NCBI chr 2:247,392,195...247,662,026
Ensembl chr 2:247,403,920...247,446,882
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of BUB1 mRNA CTD PMID:17639512 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G C3 complement C3 increases expression EXP Ascorbic Acid results in increased expression of C3 mRNA CTD PMID:15372504 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G C5 complement C5 multiple interactions ISO Ascorbic Acid inhibits the reaction [Asbestos, Crocidolite results in increased cleavage of C5 protein]; Ascorbic Acid inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein] CTD PMID:10777245 NCBI chr 3:14,049,993...14,113,931
NCBI chr 3:14,206,466...14,229,141
Ensembl chr 3:14,049,995...14,229,080
JBrowse link
G Ca9 carbonic anhydrase 9 multiple interactions ISO Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of CA9 protein] CTD PMID:16288478 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Calb2 calbindin 2 multiple interactions EXP Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CALB2 protein] CTD PMID:31708536 NCBI chr19:41,482,743...41,509,617
Ensembl chr19:41,482,728...41,509,658
JBrowse link
G Car2 carbonic anhydrase 2 increases expression ISO Ascorbic Acid results in increased expression of CAR2 mRNA CTD PMID:15730627 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp2 caspase 2 multiple interactions EXP Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein] CTD PMID:15158148 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
decreases activity
ISO
EXP
[Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP3 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP3 mRNA]; [juglone co-treated with Ascorbic Acid] results in decreased expression of CASP3 protein; Ascorbic Acid inhibits the reaction [deoxynivalenol results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [Fenretinide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Oleanolic Acid results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [Reactive Oxygen Species results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in decreased expression of CASP3 mRNA]; Ascorbic Acid inhibits the reaction [Silicon Dioxide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP3 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein]
Ascorbic Acid inhibits the reaction [glycidamide results in increased expression of CASP3 mRNA]
Ascorbic Acid results in increased expression of CASP3 mRNA
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CASP3 protein]; [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of CASP3 protein]; Ascorbic Acid inhibits the reaction [Arsenic results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP3 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]
Ascorbic Acid results in decreased activity of CASP3 protein
CTD PMID:12750841, PMID:15158148, PMID:16124896, PMID:16407847, PMID:16867262, PMID:16973328, PMID:17166419, PMID:17301063, PMID:17618090, PMID:17879260, PMID:18758938, PMID:20356860, PMID:21262251, PMID:21873648, PMID:22245848, PMID:22678527, PMID:23711929, PMID:24295472, PMID:24488945, PMID:29992683, PMID:30597948, PMID:31739238, PMID:32632975 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 multiple interactions EXP Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CASP4 mRNA] CTD PMID:18544905 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp6 caspase 6 multiple interactions EXP Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP6 protein] CTD PMID:15158148 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 multiple interactions ISO [Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of CASP7 protein]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CASP7 mRNA]; Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP7 protein] CTD PMID:17301063, PMID:17879260 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
EXP
ISO
[Ascorbic Acid co-treated with INS1 protein] results in increased expression of CASP8 mRNA; [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA
Ascorbic Acid results in increased expression of CASP8 mRNA
Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]
CTD PMID:18544905, PMID:20400526, PMID:23711929, PMID:30597948 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased activity of CASP9 protein]
Ascorbic Acid inhibits the reaction [TNFSF10 protein results in increased activity of CASP9 protein]
CTD PMID:15158148, PMID:16973328, PMID:23711929 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin increases expression EXP Ascorbic Acid results in increased expression of CAST mRNA CTD PMID:15372504 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase affects expression
increases activity
increases expression
decreases activity
multiple interactions
decreases response to substance
ISO
EXP
Ascorbic Acid affects the expression of CAT protein
Ascorbic Acid results in increased activity of CAT protein
Ascorbic Acid results in increased expression of CAT mRNA
Ascorbic Acid results in decreased activity of CAT protein
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Lead] results in increased expression of CAT protein; [Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased activity of CAT protein]; [Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; [Zinc co-treated with Vitamin E co-treated with Ascorbic Acid co-treated with sodium arsenite] results in increased activity of CAT protein; Ascorbic Acid inhibits the reaction [abamectin results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Arsenic results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cadmium results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cyclosporine results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Food Additives affects the activity of CAT protein]; Ascorbic Acid inhibits the reaction [Indomethacin results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of CAT mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of CAT protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased activity of CAT protein]
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Air Pollutants, Occupational affects the expression of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Malathion results in increased activity of CAT protein]; [Ascorbic Acid co-treated with Vitamin E] results in increased expression of CAT mRNA; [juglone co-treated with Ascorbic Acid] results in decreased activity of CAT protein; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of CAT mRNA]; Ascorbic Acid inhibits the reaction [Dimethoate results in increased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Malathion results in increased activity of CAT protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK9 protein]; CAT protein inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; CAT protein results in decreased susceptibility to [Arsenic Trioxide co-treated with Ascorbic Acid]; CAT results in decreased susceptibility to [Vitamin K 3 co-treated with Ascorbic Acid]
Ascorbic Acid results in increased expression of CAT protein
[Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of IREB2 protein]; [Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of TFRC protein]; Ascorbic Acid inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Ascorbic Acid inhibits the reaction [fipronil results in decreased activity of CAT protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased degradation of Hyaluronic Acid]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR2 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TLR4 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of TNF protein]; CAT protein inhibits the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]
CAT protein results in decreased susceptibility to Ascorbic Acid
CTD PMID:10772068, PMID:12540038, PMID:12767684, PMID:14698046, PMID:15104111, PMID:16248992, PMID:16298753, PMID:16758767, PMID:17512118, PMID:17822687, PMID:18073202, PMID:18096215, PMID:18548748, PMID:18655177, PMID:18715643, PMID:18726076, PMID:19298665, PMID:19391111, PMID:19429265, PMID:20028703, PMID:20077558, PMID:20122981, PMID:20171736, PMID:20535553, PMID:20876158, PMID:21310208, PMID:21689642, PMID:22008531, PMID:22056337, PMID:22207723, PMID:23194016, PMID:23470461, PMID:23619517, PMID:23692848, PMID:24295472, PMID:24488945, PMID:25721553, PMID:29572072, PMID:29992683, PMID:31005848, PMID:31022331, PMID:31576639, PMID:31610155, PMID:31739238 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbs cystathionine beta synthase decreases expression ISO Ascorbic Acid results in decreased expression of CBS mRNA CTD PMID:19197388 NCBI chr20:10,361,987...10,386,663
Ensembl chr20:10,361,988...10,386,751
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 affects expression
decreases expression
ISO Ascorbic Acid affects the expression of CCL2 mRNA; Ascorbic Acid deficiency affects the expression of CCL2 mRNA
Ascorbic Acid results in decreased expression of CCL2 mRNA
CTD PMID:19932582, PMID:21796779 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL21A mRNA CTD PMID:17917374 NCBI chr 5:58,197,678...58,198,782
Ensembl chr 5:58,197,680...58,198,782
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL3 mRNA CTD PMID:17917374 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccna1 cyclin A1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNA1 protein] CTD PMID:21621607 NCBI chr 2:144,456,689...144,503,570
Ensembl chr 2:144,458,153...144,467,912
JBrowse link
G Ccnb1 cyclin B1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNB1 protein] CTD PMID:21621607 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnc cyclin C multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNC mRNA CTD PMID:17917374 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCND1 mRNA; Ascorbic Acid inhibits the reaction [phenylhydrazine results in decreased expression of CCND1 mRNA]
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND1 protein]
Ascorbic Acid results in decreased expression of CCND1 mRNA
CTD PMID:17917374, PMID:21621607, PMID:21919647, PMID:30140404 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 multiple interactions ISO
EXP
[Quercetin co-treated with Ascorbic Acid] results in increased expression of CCND2 mRNA
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND2 protein]
CTD PMID:17639512, PMID:21621607 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccnd3 cyclin D3 multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCND3 protein]
Ascorbic Acid promotes the reaction [juglone results in decreased expression of CCND3 protein]
CTD PMID:21621607, PMID:29992683 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne2 cyclin E2 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CCNE2 protein] CTD PMID:21621607 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNG1 mRNA
[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of CCNG1 mRNA
CTD PMID:17917374, PMID:18544905 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Cd24 CD24 molecule multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of CD24 mRNA CTD PMID:17639512 NCBI chr20:48,335,540...48,340,847
Ensembl chr20:48,335,540...48,340,846
JBrowse link
G Cd34 CD34 molecule multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CD34 mRNA CTD PMID:16443354 NCBI chr13:113,691,842...113,711,259
Ensembl chr13:113,691,932...113,711,647
JBrowse link
G Cd40 CD40 molecule multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CD40 mRNA CTD PMID:16443354 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of CD44 protein] CTD PMID:23692848 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd48 Cd48 molecule increases expression EXP Ascorbic Acid results in increased expression of CD48 mRNA CTD PMID:15372504 NCBI chr13:90,116,601...90,140,371
Ensembl chr13:90,116,843...90,140,371
JBrowse link
G Cd69 Cd69 molecule decreases expression ISO Ascorbic Acid deficiency results in decreased expression of CD69 protein CTD PMID:22306178 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cd82 Cd82 molecule increases expression EXP Ascorbic Acid results in increased expression of CD82 mRNA CTD PMID:15372504 NCBI chr 3:82,324,344...82,368,846
Ensembl chr 3:82,324,354...82,368,357
JBrowse link
G Cdc6 cell division cycle 6 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of CDC6 mRNA CTD PMID:17639512 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdh13 cadherin 13 increases expression ISO Ascorbic Acid results in increased expression of CDH13 mRNA CTD PMID:15305145 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdh2 cadherin 2 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CDH2 protein] CTD PMID:29940330 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdh22 cadherin 22 increases expression EXP Ascorbic Acid results in increased expression of CDH22 mRNA CTD PMID:15372504 NCBI chr 3:161,574,993...161,971,102
Ensembl chr 3:161,575,631...161,917,285
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK1 protein] CTD PMID:21621607 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK2 protein] CTD PMID:21621607 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK4 protein]
[juglone co-treated with Ascorbic Acid] results in decreased expression of CDK4 protein
CTD PMID:21621607, PMID:29992683 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk6 cyclin-dependent kinase 6 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of CDK6 protein] CTD PMID:21621607 NCBI chr 4:27,781,728...27,969,653
Ensembl chr 4:27,785,647...27,966,398
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA
Ascorbic Acid results in increased expression of CDKN1A mRNA
[INS1 protein co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]
[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA; Ascorbic Acid inhibits the reaction [potassium bromate results in increased expression of CDKN1A protein]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA]
CTD PMID:17917374, PMID:20067818, PMID:20400526, PMID:20530418 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA CTD PMID:18544905 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of CDKN2A protein] CTD PMID:21621607 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of CEBPA protein
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA
CTD PMID:14505802, PMID:25932594 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression EXP Ascorbic Acid results in increased expression of CEBPB mRNA CTD PMID:15372504 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cfb complement factor B multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of CFB mRNA CTD PMID:17639512 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cftr CF transmembrane conductance regulator multiple interactions
increases activity
ISO [Bicarbonates co-treated with Glutathione co-treated with Ascorbic Acid] results in increased activity of CFTR protein; Ascorbic Acid promotes the reaction [CFTR protein results in increased secretion of Chlorides]
Ascorbic Acid results in increased activity of CFTR protein
CTD PMID:14993613, PMID:32374624 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chaf1b chromatin assembly factor 1 subunit B multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of CHAF1B mRNA CTD PMID:26424790 NCBI chr11:34,101,248...34,121,371
Ensembl chr11:34,101,197...34,121,378
JBrowse link
G Chat choline O-acetyltransferase multiple interactions EXP [Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein; Tobacco Smoke Pollution inhibits the reaction [[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein] CTD PMID:25891525 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA]
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of CHEK2 protein]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of CHEK2 protein modified form]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased phosphorylation of CHEK2 protein]
CTD PMID:18544905, PMID:25977998, PMID:31388677 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Cit citron rho-interacting serine/threonine kinase multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of CIT mRNA CTD PMID:17639512 NCBI chr12:46,334,669...46,494,152
Ensembl chr12:46,334,665...46,494,174
JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA] CTD PMID:28189605 NCBI chr  X:72,128,996...72,133,692
Ensembl chr  X:72,128,994...72,133,692
JBrowse link
G Clu clusterin increases expression EXP Ascorbic Acid results in increased expression of CLU mRNA CTD PMID:15372504 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cmip c-Maf-inducing protein increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of CMIP mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of CMIP mRNA
CTD PMID:25555879 NCBI chr19:49,792,273...50,000,535
Ensembl chr19:49,792,273...50,000,535
JBrowse link
G Cnn1 calponin 1 multiple interactions
increases expression
ISO
EXP
[Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of CNN1 mRNA; [Ascorbic Acid co-treated with TGFB1 protein] results in increased expression of CNN1 protein
Ascorbic Acid results in increased expression of CNN1 protein
CTD PMID:14639096, PMID:18607632 NCBI chr 8:23,113,083...23,121,748
Ensembl chr 8:23,113,048...23,121,761
JBrowse link
G Cntf ciliary neurotrophic factor multiple interactions ISO Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Ascorbic Acid inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]] CTD PMID:16896058 NCBI chr 1:229,599,009...229,601,032
Ensembl chr 1:229,599,009...229,601,032
JBrowse link
G Cntnap1 contactin associated protein 1 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of CNTNAP1 mRNA CTD PMID:25555879 NCBI chr10:89,087,904...89,103,615
Ensembl chr10:89,089,646...89,103,614
JBrowse link
G Col10a1 collagen type X alpha 1 chain increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of COL10A1 mRNA
U 0126 inhibits the reaction [Ascorbic Acid results in increased expression of COL10A1 mRNA]
CTD PMID:20530736 NCBI chr20:41,180,295...41,190,664
Ensembl chr20:41,184,287...41,189,633
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of COL1A1 mRNA
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of COL1A1 mRNA
CTD PMID:12510807, PMID:14566779, PMID:28105418, PMID:31935364 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
multiple interactions
EXP
ISO
Ascorbic Acid results in increased expression of COL1A2 mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of COL1A2 mRNA
CTD PMID:15372504, PMID:25555879 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col2a1 collagen type II alpha 1 chain increases expression
multiple interactions
EXP
ISO
Ascorbic Acid results in increased expression of COL2A1 mRNA
[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]; resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]]
CTD PMID:15372504, PMID:26526931 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Cr2 complement C3d receptor 2 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CR2 mRNA CTD PMID:16443354 NCBI chr13:113,890,274...113,927,824
Ensembl chr13:113,890,272...113,927,877
JBrowse link
G Crip2 cysteine-rich protein 2 increases expression EXP Ascorbic Acid results in increased expression of CRIP2 mRNA CTD PMID:15372504 NCBI chr 6:137,953,545...137,958,491
Ensembl chr 6:137,953,545...137,958,490
JBrowse link
G Crp C-reactive protein multiple interactions ISO [Vitamin E co-treated with Ascorbic Acid co-treated with Folic Acid co-treated with Riboflavin co-treated with Vitamin B 6 co-treated with Vitamin B 12] results in decreased expression of CRP protein; [Vitamin E co-treated with Ascorbic Acid] results in decreased expression of CRP protein CTD PMID:16517955 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Cryab crystallin, alpha B increases expression EXP Ascorbic Acid results in increased expression of CRYAB mRNA CTD PMID:15372504 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Cs citrate synthase multiple interactions ISO Ascorbic Acid inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr 7:2,752,680...2,778,963
Ensembl chr 7:2,752,680...2,778,963
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 increases expression ISO Ascorbic Acid results in increased expression of CSPG5 mRNA CTD PMID:15305145 NCBI chr 8:118,333,695...118,348,040
Ensembl chr 8:118,333,706...118,347,582
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 increases expression EXP Ascorbic Acid results in increased expression of CSRP1 mRNA CTD PMID:15372504 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Cst6 cystatin E/M increases expression EXP Ascorbic Acid results in increased expression of CST6 mRNA CTD PMID:15372504 NCBI chr 1:220,727,292...220,729,000
Ensembl chr 1:220,727,292...220,729,000
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and affects the localization of CTNNB1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of CTNNB1 protein] CTD PMID:29940330 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctps2 CTP synthase 2 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of CTPS2 mRNA CTD PMID:25555879 NCBI chr  X:33,383,087...33,522,852
Ensembl chr  X:33,383,087...33,522,836
JBrowse link
G Ctsd cathepsin D multiple interactions EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of CTSD protein] CTD PMID:17045618 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctsk cathepsin K increases expression ISO Ascorbic Acid results in increased expression of CTSK mRNA CTD PMID:15730627 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Ctso cathepsin O multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of CTSO mRNA CTD PMID:17639512 NCBI chr 2:180,857,178...180,881,677 JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP Ascorbic Acid deficiency results in increased expression of CXCL1 mRNA; Ascorbic Acid deficiency results in increased expression of CXCL1 protein CTD PMID:16637227 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression
increases expression
ISO Ascorbic Acid results in decreased expression of CXCL10 mRNA
Ascorbic Acid deficiency results in increased expression of CXCL10 mRNA
CTD PMID:19932582 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 decreases expression
increases expression
ISO Ascorbic Acid results in decreased expression of CXCL6 mRNA
Ascorbic Acid deficiency results in increased expression of CXCL6 mRNA
CTD PMID:19932582 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of CXCL9 mRNA CTD PMID:16443354 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of CXCR5 mRNA CTD PMID:16443354 NCBI chr 8:48,835,688...48,852,032
Ensembl chr 8:48,836,957...48,850,671
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions ISO Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of CYBA protein] CTD PMID:25305479 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO Ascorbic Acid results in increased expression of NOX2 protein CTD PMID:21570463 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cybrd1 cytochrome b reductase 1 decreases expression
increases expression
ISO Ascorbic Acid results in decreased expression of CYBRD1 protein
Ascorbic Acid results in increased expression of CYBRD1 protein
CTD PMID:18815723 NCBI chr 3:57,718,496...57,745,749
Ensembl chr 3:57,718,364...57,746,097
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO Ascorbic Acid inhibits the reaction [TNFSF10 protein affects the localization of CYCS protein] CTD PMID:23711929 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions
increases expression
EXP
ISO
Ascorbic Acid inhibits the reaction [Cadmium results in decreased expression of CYP11A1 mRNA]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of CYP11A1 protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 mRNA]
Ascorbic Acid results in increased expression of CYP11A1 mRNA
CTD PMID:15223132, PMID:16298753, PMID:17280759, PMID:17901237 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of CYP19A1 mRNA
Ascorbic Acid results in increased expression of CYP19A1 mRNA
CTD PMID:16443354, PMID:17901237 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of CYP1A1 mRNA; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]
Ascorbic Acid affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Ascorbic Acid affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of CYP1A1 mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]
Ascorbic Acid results in decreased activity of CYP1A1 protein
CTD PMID:16517059, PMID:17512695, PMID:17639512, PMID:19268519, PMID:21094198 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP Ascorbic Acid deficiency results in increased expression of CYP1A2 mRNA; Ascorbic Acid deficiency results in increased expression of CYP1A2 protein CTD PMID:8269614 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2A5 mRNA; Ascorbic Acid inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2A5 protein] CTD PMID:17917374, PMID:22552773 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2B10 mRNA CTD PMID:17917374 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 decreases expression EXP Ascorbic Acid deficiency results in decreased expression of CYP2B2 protein CTD PMID:8269614 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2B9 mRNA CTD PMID:17917374 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
multiple interactions
ISO
EXP
Ascorbic Acid results in decreased activity of CYP2E1 protein
[Ascorbic Acid co-treated with Sesame Oil] inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]; Ascorbic Acid inhibits the reaction [abamectin results in increased expression of CYP2E1 protein]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of CYP2E1 protein]
CTD PMID:17512695, PMID:31585129, PMID:31739238 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions ISO [Diethylnitrosamine co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA CTD PMID:17917374 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dab2 DAB adaptor protein 2 decreases expression ISO Ascorbic Acid results in decreased expression of DAB2 mRNA CTD PMID:15305145 NCBI chr 2:55,747,353...55,768,848
Ensembl chr 2:55,747,318...55,768,270
JBrowse link
G Dclk1 doublecortin-like kinase 1 increases expression ISO Ascorbic Acid results in increased expression of DCLK1 mRNA CTD PMID:15305145 NCBI chr 2:144,646,255...144,939,389
Ensembl chr 2:144,646,308...144,936,927
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DDIT3 mRNA CTD PMID:18544905 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO Ascorbic Acid results in decreased expression of DKK1 mRNA CTD PMID:19197388 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dkk2 dickkopf WNT signaling pathway inhibitor 2 multiple interactions ISO Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in decreased expression of DKK2 mRNA]; Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in increased methylation of DKK2 promoter] CTD PMID:27901495 NCBI chr 2:237,148,918...237,240,883
Ensembl chr 2:237,148,941...237,241,350
JBrowse link
G Dld dihydrolipoamide dehydrogenase multiple interactions ISO Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of and results in increased phosphorylation of DLD protein] CTD PMID:29158198 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlgap5 DLG associated protein 5 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of DLGAP5 mRNA CTD PMID:17639512 NCBI chr15:24,167,484...24,199,417
Ensembl chr15:24,167,486...24,199,341
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA; bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA] CTD PMID:25932594 NCBI chr14:6,889,851...6,923,961
Ensembl chr14:6,889,856...6,900,733
JBrowse link
G Dnajc10 DnaJ heat shock protein family (Hsp40) member C10 multiple interactions ISO Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of DNAJC10 mRNA] CTD PMID:17353921 NCBI chr 3:67,538,289...67,578,308
Ensembl chr 3:67,538,289...67,578,306
JBrowse link
G Dnase1 deoxyribonuclease 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of DNASE1 mRNA CTD PMID:17639512 NCBI chr10:11,757,681...11,760,672
Ensembl chr10:11,757,682...11,760,620
JBrowse link
G Dpf1 double PHD fingers 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of DPF1 mRNA CTD PMID:26424790 NCBI chr 1:87,248,448...87,258,070
Ensembl chr 1:87,248,489...87,258,070
JBrowse link
G Dpp4 dipeptidylpeptidase 4 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of DPP4 mRNA CTD PMID:17639512 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Dppa5 developmental pluripotency associated 5 decreases expression ISO Ascorbic Acid results in decreased expression of DPPA5A mRNA CTD PMID:15305145 NCBI chr 8:85,711,560...85,713,313
Ensembl chr 8:85,711,795...85,712,647
Ensembl chr 7:85,711,795...85,712,647
Ensembl chr 3:85,711,795...85,712,647
JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP Ascorbic Acid results in decreased expression of DUSP6 mRNA CTD PMID:15372504 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of EDN1 mRNA CTD PMID:16443354 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Edn3 endothelin 3 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of EDN3 mRNA CTD PMID:16443354 NCBI chr 3:172,856,730...172,879,276
Ensembl chr 3:172,856,733...172,880,450
JBrowse link
G Ednrb endothelin receptor type B increases expression ISO Ascorbic Acid results in increased expression of EDNRB mRNA CTD PMID:15305145 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Ascorbic Acid results in decreased expression of EGFR mRNA CTD PMID:21919647 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 multiple interactions ISO EGLN1 mRNA affects the reaction [Ascorbic Acid results in increased expression of SP7 protein] CTD PMID:21467157 NCBI chr19:57,660,194...57,701,158
Ensembl chr19:57,662,278...57,699,113
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of EGLN3 mRNA CTD PMID:17639512 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta decreases expression ISO Ascorbic Acid results in decreased expression of EIF2S2 mRNA CTD PMID:19197388 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A decreases expression ISO Ascorbic Acid results in decreased expression of EIF3A mRNA CTD PMID:19197388 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C decreases expression ISO Ascorbic Acid results in decreased expression of EIF3C mRNA CTD PMID:19197388 NCBI chr 1:197,964,406...197,982,917
Ensembl chr 1:197,964,407...197,982,601
JBrowse link
G Eif3i eukaryotic translation initiation factor 3, subunit I increases expression ISO Ascorbic Acid results in increased expression of EIF3I mRNA CTD PMID:22139585 NCBI chr 5:147,796,580...147,803,853
Ensembl chr 5:147,796,662...147,803,851
JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 decreases expression ISO Ascorbic Acid results in decreased expression of EIF4A1 mRNA CTD PMID:19197388 NCBI chr10:56,271,257...56,276,764
Ensembl chr10:56,271,257...56,276,764
JBrowse link
G Elp6 elongator acetyltransferase complex subunit 6 multiple interactions
decreases expression
ISO [arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of ELP6 mRNA
Ascorbic Acid results in decreased expression of ELP6 mRNA
CTD PMID:25555879 NCBI chr 8:118,525,770...118,541,074
Ensembl chr 8:118,525,682...118,541,073
JBrowse link
G Emp1 epithelial membrane protein 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP1 mRNA CTD PMID:17639512 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Emp3 epithelial membrane protein 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of EMP3 mRNA CTD PMID:17639512 NCBI chr 1:101,900,731...101,903,948
Ensembl chr 1:101,900,733...101,903,910
JBrowse link
G En1 engrailed homeobox 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in decreased expression of EN1 mRNA]; Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in increased methylation of EN1 promoter] CTD PMID:27901495 NCBI chr13:36,532,758...36,537,888
Ensembl chr13:36,532,758...36,537,093
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein] CTD PMID:16288478 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:17639512 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX2 mRNA CTD PMID:17639512 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Eprs glutamyl-prolyl-tRNA synthetase decreases expression ISO Ascorbic Acid results in decreased expression of EPRS1 mRNA CTD PMID:19197388 NCBI chr13:103,300,911...103,371,651
Ensembl chr13:103,300,932...103,371,577
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC2 mRNA CTD PMID:17917374 NCBI chr 1:80,293,574...80,307,334
Ensembl chr 1:80,293,566...80,307,344
JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC4 mRNA CTD PMID:17917374 NCBI chr10:2,010,140...2,037,953
Ensembl chr10:2,010,648...2,037,891
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC5 mRNA CTD PMID:17917374 NCBI chr 9:50,928,847...50,970,962
Ensembl chr 9:50,925,619...50,970,955
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR1 mRNA] CTD PMID:18602937 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of ESR2 mRNA] CTD PMID:18602937 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of EZH1 mRNA CTD PMID:26424790 NCBI chr10:89,104,026...89,139,978
Ensembl chr10:89,104,027...89,130,339
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of EZH2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of EZH2 protein; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA]; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of TNFRSF11B mRNA] CTD PMID:26424790 NCBI chr 4:77,284,404...77,347,011
Ensembl chr 4:77,284,404...77,347,011
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA] CTD PMID:23114885 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fabp4 fatty acid binding protein 4 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with Firemaster 550] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS1 protein co-treated with triphenyl phosphate] results in increased expression of FABP4 mRNA; d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA] CTD PMID:25062436, PMID:25932594, PMID:32473317 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fabp6 fatty acid binding protein 6 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of FABP6 mRNA CTD PMID:17639512 NCBI chr10:29,191,621...29,196,593
Ensembl chr10:29,191,623...29,196,563
JBrowse link
G Fancl FA complementation group L multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of FANCL mRNA CTD PMID:26424790 NCBI chr14:110,675,306...110,740,880
Ensembl chr14:110,676,090...110,740,317
JBrowse link
G Fat1 FAT atypical cadherin 1 multiple interactions
increases expression
ISO [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of FAT1 mRNA
Ascorbic Acid results in increased expression of FAT1 mRNA
CTD PMID:25555879 NCBI chr16:50,372,150...50,501,716
Ensembl chr16:50,372,128...50,501,921
JBrowse link
G Fbln1 fibulin 1 increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of FBLN1 mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of FBLN1 mRNA
CTD PMID:25555879 NCBI chr 7:126,096,793...126,176,468
Ensembl chr 7:126,096,793...126,176,468
JBrowse link
G Fbp1 fructose-bisphosphatase 1 affects expression ISO Ascorbic Acid affects the expression of FBP1 protein CTD PMID:19224539 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fdxr ferredoxin reductase increases expression EXP Ascorbic Acid results in increased expression of FDXR mRNA CTD PMID:15372504 NCBI chr10:103,817,724...103,826,413
Ensembl chr10:103,817,704...103,826,448
JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Ascorbic Acid results in decreased expression of FLT1 mRNA CTD PMID:21919647 NCBI chr12:9,033,993...9,205,886
Ensembl chr12:9,034,308...9,205,905
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of FMO1 mRNA CTD PMID:17639512 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of FMO5 mRNA CTD PMID:17639512 NCBI chr 2:199,796,870...199,823,927
Ensembl chr 2:199,796,881...199,823,927
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein] CTD PMID:27385396 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO [Ascorbic Acid co-treated with Quartz] results in increased expression of FN1 mRNA; [Tretinoin co-treated with Ascorbic Acid] results in increased expression of FN1 mRNA CTD PMID:16443354, PMID:27381660 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fn3krp fructosamine-3-kinase-related protein increases expression ISO Ascorbic Acid results in increased expression of FN3KRP mRNA CTD PMID:25555879 NCBI chr10:110,614,739...110,622,625
Ensembl chr10:110,614,713...110,623,519
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO Ascorbic Acid results in increased expression of FOS mRNA CTD PMID:15305145 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxa2 forkhead box A2 multiple interactions EXP Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of FOXA2 protein] CTD PMID:16863852 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G Foxj1 forkhead box J1 multiple interactions
increases expression
ISO
EXP
[Tretinoin co-treated with Ascorbic Acid] results in increased expression of FOXJ1 mRNA
Ascorbic Acid results in increased expression of FOXJ1 mRNA
CTD PMID:15372504, PMID:16443354 NCBI chr10:105,282,090...105,289,396 JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions EXP Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of FSHB protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of FSHB protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased expression of FSHB protein] CTD PMID:16248992, PMID:17280759, PMID:18602937, PMID:23470461 NCBI chr 3:98,088,321...98,092,131
Ensembl chr 3:98,088,324...98,092,131
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of FSHR mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of FSHR protein] CTD PMID:18602937, PMID:23470461 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression EXP Ascorbic Acid results in increased expression of FTH1 mRNA CTD PMID:15372504 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 affects expression ISO Ascorbic Acid affects the expression of FTL protein CTD PMID:19224539 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO Ascorbic Acid inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of FYN protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased phosphorylation of FYN protein] CTD PMID:14572611 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Fzd2 frizzled class receptor 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of FZD2 mRNA CTD PMID:17639512 NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
JBrowse link
G G0s2 G0/G1switch 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of G0S2 mRNA CTD PMID:17639512 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of G6PD protein] CTD PMID:18548748 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabarap GABA type A receptor-associated protein increases expression ISO Ascorbic Acid results in increased expression of GABARAP mRNA CTD PMID:15305145 NCBI chr10:56,601,288...56,604,223
Ensembl chr10:56,601,288...56,604,221
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA CTD PMID:18544905 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gak cyclin G associated kinase multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of GAK mRNA CTD PMID:16443354 NCBI chr14:2,100,104...2,174,332
Ensembl chr14:2,100,106...2,174,318
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GAL protein] CTD PMID:17045618 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Gamt guanidinoacetate N-methyltransferase affects expression ISO Ascorbic Acid affects the expression of GAMT protein CTD PMID:19224539 NCBI chr 7:12,314,848...12,317,998
Ensembl chr 7:12,314,848...12,317,998
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Ascorbic Acid results in increased expression of GAPDH protein CTD PMID:22139585 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gars glycyl-tRNA synthetase decreases expression ISO Ascorbic Acid results in decreased expression of GARS1 mRNA CTD PMID:19197388 NCBI chr 4:85,235,122...85,276,085
Ensembl chr 4:85,235,172...85,276,044
JBrowse link
G Gas7 growth arrest specific 7 increases expression ISO Ascorbic Acid results in increased expression of GAS7 mRNA CTD PMID:15305145 NCBI chr10:54,010,723...54,240,805
Ensembl chr10:54,126,486...54,236,476
JBrowse link
G Gata1 GATA binding protein 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of GATA1 mRNA CTD PMID:16443354 NCBI chr  X:15,273,937...15,281,759
Ensembl chr  X:15,378,789...15,382,066
JBrowse link
G Gata4 GATA binding protein 4 increases expression ISO Ascorbic Acid results in increased expression of GATA4 mRNA CTD PMID:12668514 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression EXP Ascorbic Acid results in increased expression of GBP2 mRNA CTD PMID:15372504 NCBI chr 2:248,276,795...248,293,784
Ensembl chr 2:248,276,709...248,293,784
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of GCLC mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of GCLC protein]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of GCLC mRNA]] CTD PMID:27028516, PMID:31585129 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gdf10 growth differentiation factor 10 multiple interactions EXP [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of GDF10 mRNA CTD PMID:15994055 NCBI chr16:10,250,508...10,262,383
Ensembl chr16:10,250,404...10,263,150
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression EXP Ascorbic Acid results in decreased expression of GFAP protein CTD PMID:15372504 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gfra1 GDNF family receptor alpha 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of GFRA1 mRNA CTD PMID:16443354 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GGT1 protein] CTD PMID:16298753 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of GH1 protein] CTD PMID:18602937 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of GJA1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GJA1 protein] CTD PMID:29940330 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Glo1 glyoxalase 1 affects expression ISO Ascorbic Acid affects the expression of GLO1 protein CTD PMID:19224539 NCBI chr20:9,273,589...9,291,608
Ensembl chr20:9,273,594...9,291,610
JBrowse link
G Glrx glutaredoxin multiple interactions EXP Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GLRX mRNA] CTD PMID:23470461 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Gls glutaminase multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of GLS mRNA CTD PMID:17639512 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gng3 G protein subunit gamma 3 increases expression ISO Ascorbic Acid results in increased expression of GNG3 mRNA CTD PMID:15305145 NCBI chr 1:225,033,921...225,035,687
Ensembl chr 1:225,033,921...225,035,687
JBrowse link
G Gng4 G protein subunit gamma 4 increases expression ISO Ascorbic Acid results in increased expression of GNG4 mRNA CTD PMID:15305145 NCBI chr17:90,266,571...90,316,278
Ensembl chr17:90,266,794...90,315,492
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Ascorbic Acid results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Gpc1 glypican 1 multiple interactions
increases expression
increases degradation
ISO [Ascorbic Acid co-treated with Nitric Oxide] results in increased degradation of GPC1 protein modified form; Zinc promotes the reaction [[Ascorbic Acid co-treated with Nitric Oxide] results in increased degradation of GPC1 protein modified form]
Ascorbic Acid results in increased expression of GPC1 mRNA
Ascorbic Acid results in increased degradation of GPC1 protein
CTD PMID:15677459, PMID:21642435, PMID:25555879 NCBI chr 9:99,998,275...100,026,818
Ensembl chr 9:99,998,275...100,026,818
JBrowse link
G Gpc3 glypican 3 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of GPC3 mRNA] CTD PMID:28189605 NCBI chr  X:139,579,268...139,947,093
Ensembl chr  X:139,579,268...139,916,883
JBrowse link
G Gpd1 glycerol-3-phosphate dehydrogenase 1 multiple interactions EXP [Ascorbic Acid co-treated with INS1 protein] results in decreased expression of GPD1 mRNA CTD PMID:20400526 NCBI chr 7:141,368,928...141,377,931
Ensembl chr 7:141,370,491...141,377,928
JBrowse link
G Gpn1 GPN-loop GTPase 1 multiple interactions
decreases expression
ISO [arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of GPN1 mRNA
Ascorbic Acid results in decreased expression of GPN1 mRNA
CTD PMID:25555879 NCBI chr 6:26,255,081...26,272,755
Ensembl chr 6:26,242,925...26,272,808
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Ascorbic Acid inhibits the reaction [Cyclosporine results in increased activity of GPT protein]; Ascorbic Acid inhibits the reaction [Food Additives results in increased activity of GPT protein] CTD PMID:16758767, PMID:19391111 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO
EXP
[Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 mRNA; [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA; [Vitamin A co-treated with Ascorbic Acid co-treated with Vitamin E] results in increased expression of GPX1 protein; Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of GPX1 mRNA]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA]
Ascorbic Acid results in increased expression of GPX1 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GPX1 protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GPX1 protein]
CTD PMID:15372504, PMID:16248992, PMID:16298753, PMID:17179735, PMID:20530418, PMID:22207723, PMID:29663635, PMID:31576639, PMID:31610155 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of GPX2 mRNA; [Tretinoin co-treated with Ascorbic Acid] results in increased expression of GPX2 mRNA CTD PMID:16443354, PMID:17639512 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression EXP Ascorbic Acid results in increased expression of GPX4 mRNA CTD PMID:15372504 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grn granulin precursor increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of GRN mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of GRN mRNA
CTD PMID:25555879 NCBI chr10:90,377,103...90,383,207
Ensembl chr10:90,376,933...90,383,205
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases expression
multiple interactions
EXP Ascorbic Acid results in decreased expression of GSK3B mRNA
Ascorbic Acid inhibits the reaction [Excitatory Amino Acid Agonists results in increased phosphorylation of GSK3B protein]
CTD PMID:15372504, PMID:24675465 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO
EXP
[Ascorbic Acid co-treated with GSR protein] affects the metabolism of Glucose; [juglone co-treated with Ascorbic Acid] results in decreased activity of GSR protein
Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [bisphenol A results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Cyclosporine results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSR mRNA]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased expression of GSR protein]
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of GSR mRNA; Ascorbic Acid inhibits the reaction [arsenic trioxide results in decreased activity of GSR protein]; Ascorbic Acid inhibits the reaction [Cadmium Chloride results in decreased activity of GSR protein]
CTD PMID:1901343, PMID:12767684, PMID:16248992, PMID:16298753, PMID:17917374, PMID:18548748, PMID:18715643, PMID:19391111, PMID:19429265, PMID:23194016, PMID:23470461, PMID:29992683, PMID:32407874 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of GSTA1 mRNA CTD PMID:17639512 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions ISO Ascorbic Acid promotes the reaction [sodium arsenite results in increased expression of GSTA1 mRNA] CTD PMID:16517059 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions EXP Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTA4 mRNA] CTD PMID:23470461 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 multiple interactions ISO Ascorbic Acid promotes the reaction [sodium arsenite results in increased expression of GSTA1 mRNA] CTD PMID:16517059 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance
multiple interactions
ISO
EXP
GSTM1 affects the susceptibility to Ascorbic Acid deficiency
Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of GSTM1 mRNA]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTM1 mRNA]
GSTM1 gene polymorphism affects the susceptibility to [Ascorbic Acid co-treated with tocotrienol, alpha]
CTD PMID:15668500, PMID:19710200, PMID:23470461 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions
increases expression
EXP Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of GSTM2 mRNA]
Ascorbic Acid results in increased expression of GSTM2 mRNA
CTD PMID:15372504, PMID:23470461 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of GSTO1 mRNA
Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of GSTO1 mRNA]
CTD PMID:31610155 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects response to substance ISO GSTT1 affects the susceptibility to Ascorbic Acid deficiency CTD PMID:19710200 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gtf2h1 general transcription factor IIH subunit 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of GTF2H1 mRNA CTD PMID:17639512 NCBI chr 1:102,849,618...102,877,939
Ensembl chr 1:102,849,889...102,877,944
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [lead acetate results in decreased expression of GUCY1B1 protein] CTD PMID:11729227 NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP [ferulic acid co-treated with Ascorbic Acid] inhibits the reaction [Isoproterenol results in increased activity of GUSB protein] CTD PMID:17045618 NCBI chr12:30,202,066...30,215,583
Ensembl chr12:30,198,822...30,227,771
JBrowse link
G Gzmb granzyme B decreases expression ISO Ascorbic Acid deficiency results in decreased expression of GZMB mRNA CTD PMID:22306178 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of H2AX mRNA; [Ascorbic Acid results in increased reduction of Vitamin K 3] which results in increased phosphorylation of H2AX protein CTD PMID:19482829, PMID:26424790 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP Ascorbic Acid results in decreased expression of HADHA mRNA CTD PMID:15372504 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of HAND2 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of HAND2 mRNA] CTD PMID:28189605 NCBI chr16:36,371,489...36,373,551
Ensembl chr16:36,371,489...36,373,546
JBrowse link
G Hcfc1 host cell factor C1 multiple interactions
increases expression
ISO [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of HCFC1 mRNA
Ascorbic Acid results in increased expression of HCFC1 mRNA
CTD PMID:25555879 NCBI chr  X:156,812,012...156,837,227
Ensembl chr  X:156,812,064...156,837,227
JBrowse link
G Hells helicase, lymphoid specific multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HELLS mRNA CTD PMID:26424790 NCBI chr 1:257,901,856...257,953,889
Ensembl chr 1:257,766,691...257,949,183
Ensembl chr 1:257,766,691...257,949,183
JBrowse link
G Heph hephaestin multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of HEPH mRNA CTD PMID:17639512 NCBI chr  X:65,377,313...65,658,479
Ensembl chr  X:65,563,122...65,658,516
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 decreases expression ISO Ascorbic Acid results in decreased expression of HERPUD1 mRNA CTD PMID:19197388 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of HES1 protein] CTD PMID:29663635 NCBI chr11:74,312,837...74,315,249
Ensembl chr11:74,312,806...74,315,248
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases degradation
multiple interactions
ISO
EXP
Ascorbic Acid results in increased degradation of HIF1A protein
Ascorbic Acid inhibits the reaction [AGT protein modified form results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in decreased hydroxylation of HIF1A protein]
[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [cupric chloride results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [manganese chloride results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [manganese chloride results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [Quercetin results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in increased stability of HIF1A protein]; Ascorbic Acid inhibits the reaction [Vanadates results in decreased hydroxylation of HIF1A protein]; Ascorbic Acid inhibits the reaction [Vanadates results in increased stability of HIF1A protein]; manganese chloride inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] promotes the reaction [VHL protein binds to HIF1A protein]]
CTD PMID:16288478, PMID:17364964, PMID:17382205, PMID:19074761, PMID:19263519, PMID:20881940, PMID:24188932 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D multiple interactions ISO [Arsenic Trioxide co-treated with Ascorbic Acid] results in decreased expression of H2BC5 mRNA CTD PMID:25555879 NCBI chr17:44,833,924...44,834,305
Ensembl chr17:44,833,924...44,834,305
JBrowse link
G Hk1 hexokinase 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of HK1 mRNA CTD PMID:16443354 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO Ascorbic Acid results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HMGB1 mRNA CTD PMID:26424790 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgb2 high mobility group box 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of HMGB2 mRNA CTD PMID:26424790 NCBI chr16:36,077,615...36,080,191
Ensembl chr16:36,077,617...36,080,191
Ensembl chr11:36,077,617...36,080,191
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO
EXP
Ascorbic Acid results in increased expression of HMOX1 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of HMOX1 protein]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of HMOX1 protein]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]; Hydrogen Peroxide affects the reaction [Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]]; Hydrogen Peroxide affects the reaction [Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]]; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 mRNA]; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 protein]; Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 mRNA]; Quercetin affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of HMOX1 protein]]; SB 203580 inhibits the reaction [Ascorbic Acid results in increased expression of HMOX1 protein]
Ascorbic Acid results in increased expression of HMOX1 mRNA; Ascorbic Acid results in increased expression of HMOX1 protein
[Buthionine Sulfoximine co-treated with Ascorbic Acid] promotes the reaction [Copper Sulfate results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [benzo(a)pyrene-7,8-dione results in increased expression of HMOX1 protein]; Ascorbic Acid inhibits the reaction [HMOX1 protein results in increased expression of SOD2 mRNA]; Ascorbic Acid inhibits the reaction [Resveratrol results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Resveratrol results in increased expression of HMOX1 protein]; Ascorbic Acid promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of HMOX1 mRNA]
Ascorbic Acid inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Cadmium results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in increased expression of HMOX1 mRNA]; Ascorbic Acid inhibits the reaction [Nelfinavir results in increased expression of HMOX1]; Ascorbic Acid promotes the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]
CTD PMID:8743975, PMID:10942521, PMID:15577407, PMID:16171798, PMID:16517059, PMID:19683516, PMID:21199573, PMID:22008531, PMID:22053912, PMID:23022510, PMID:27028516, PMID:29663635, PMID:29940330, PMID:31585129, PMID:31610155, PMID:32525552 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hoxa2 homeobox A2 multiple interactions ISO Ascorbic Acid inhibits the reaction [Valproic Acid results in decreased expression of HOXA2 mRNA] CTD PMID:19655241 NCBI chr 4:82,130,441...82,134,846
Ensembl chr 4:82,131,329...82,133,605
JBrowse link
G Hp haptoglobin affects activity
affects response to substance
multiple interactions
ISO Ascorbic Acid affects the activity of HP protein polymorphism
HP gene polymorphism affects the susceptibility to Ascorbic Acid deficiency
Ascorbic Acid inhibits the reaction [alpha-Tocopherol affects the activity of HP protein polymorphism]
CTD PMID:19769483, PMID:20926521 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene] CTD PMID:12467141 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of HSD17B1 mRNA] CTD PMID:18602937 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of HSD17B2 mRNA] CTD PMID:18602937 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 multiple interactions EXP Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of HSD17B3 mRNA] CTD PMID:17280759 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions
increases expression
EXP
ISO
Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of HSD3B1 mRNA]
Ascorbic Acid results in increased expression of HSD3B1 mRNA
CTD PMID:17280759, PMID:17901237
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 affects expression ISO Ascorbic Acid affects the expression of HSP90AB1 protein CTD PMID:19224539 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of HSPA1A mRNA CTD PMID:17639512 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions
decreases expression
ISO Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of HSPA5 protein]
Ascorbic Acid results in decreased expression of HSPA5 mRNA
CTD PMID:17353921, PMID:19197388 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO Ascorbic Acid results in decreased expression of HSPA9 mRNA CTD PMID:19197388 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions
increases expression
ISO
EXP
[Quercetin co-treated with Ascorbic Acid] results in increased expression of HSPB1 mRNA
Ascorbic Acid results in increased expression of HSPB1 mRNA
CTD PMID:15372504, PMID:17639512 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of HSPE1 mRNA CTD PMID:17917374 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Iapp islet amyloid polypeptide multiple interactions EXP IAPP protein promotes the reaction [[Copper co-treated with Ascorbic Acid] results in increased abundance of Hydrogen Peroxide]; IAPP protein promotes the reaction [[Copper co-treated with Ascorbic Acid] results in increased abundance of Hydroxyl Radical] CTD PMID:23793354 NCBI chr 4:176,509,863...176,517,903
Ensembl chr 4:176,510,696...176,516,083
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 decreases expression ISO Ascorbic Acid results in decreased expression of IARS1 mRNA CTD PMID:19197388 NCBI chr17:15,356,016...15,402,680
Ensembl chr17:15,355,529...15,402,649
JBrowse link
G Ibsp integrin-binding sialoprotein multiple interactions
increases expression
EXP
ISO
[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of IBSP mRNA]]
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of IBSP mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of IBSP mRNA]
Ascorbic Acid results in increased expression of IBSP mRNA
CTD PMID:26492236, PMID:27028516, PMID:28105418 NCBI chr14:6,801,200...6,813,987
Ensembl chr14:6,801,204...6,813,945
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ICAM1 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of ICAM1 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] CTD PMID:12723939, PMID:23114885, PMID:25305479, PMID:25551565 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of IER3 mRNA CTD PMID:17639512 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ifi27 interferon, alpha-inducible protein 27 increases expression EXP Ascorbic Acid results in increased expression of IFI27 mRNA CTD PMID:15372504 NCBI chr 6:127,327,959...127,334,430
Ensembl chr 6:127,327,959...127,334,428
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
ISO
EXP
IFNG protein promotes the reaction [Ascorbic Acid promotes the reaction [Quartz results in increased secretion of TNF protein]]
Ascorbic Acid inhibits the reaction [Formaldehyde results in increased expression of IFNG mRNA]
Ascorbic Acid results in decreased expression of IFNG protein
CTD PMID:14624943, PMID:19298665, PMID:27020608 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1r insulin-like growth factor 1 receptor increases expression ISO Ascorbic Acid results in increased expression of IGF1R protein CTD PMID:20530736 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions ISO
EXP
[Tretinoin co-treated with Ascorbic Acid] results in decreased expression of IGFBP5 mRNA
[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA
CTD PMID:16443354, PMID:23859036 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033
JBrowse link
G Ihh Indian hedgehog signaling molecule increases expression ISO Ascorbic Acid results in increased expression of IHH mRNA CTD PMID:20530736 NCBI chr 9:82,208,223...82,214,440
Ensembl chr 9:82,208,223...82,214,440
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 multiple interactions
decreases activity
ISO 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole inhibits the reaction [Ascorbic Acid results in decreased activity of IKZF1 protein]; 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole-3',5'-monophosphorothioate inhibits the reaction [Ascorbic Acid results in decreased activity of IKZF1 protein] CTD PMID:17664058 NCBI chr14:91,782,281...91,867,828
Ensembl chr14:91,782,354...91,867,424
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
[Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; Ascorbic Acid promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
Ascorbic Acid inhibits the reaction [Formaldehyde promotes the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]]
CTD PMID:25551565, PMID:27020608 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
Ascorbic Acid inhibits the reaction [IL1B results in increased chemical synthesis of 8-epi-prostaglandin F2alpha]; Ascorbic Acid inhibits the reaction [IL1B results in increased chemical synthesis of Dinoprostone]; Ascorbic Acid promotes the reaction [Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of 8-epi-prostaglandin F2alpha]]; Ascorbic Acid promotes the reaction [Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of Dinoprostone]]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in decreased expression of MMP13 mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA]; IL1B protein results in decreased susceptibility to [TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ACAN mRNA]]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL2A1 mRNA]]; Resveratrol inhibits the reaction [IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SOX9 mRNA]]
[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein; Ascorbic Acid inhibits the reaction [Silicon Dioxide analog promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of IL1B protein]
Ascorbic Acid deficiency promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of IL1B protein]; Ascorbic Acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Ascorbic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]
CTD PMID:15612528, PMID:16529823, PMID:22728154, PMID:23692848, PMID:24685903, PMID:26526931, PMID:28259689, PMID:30606963 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 decreases expression ISO Ascorbic Acid results in decreased expression of IL4 protein CTD PMID:14624943 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Ascorbic Acid inhibits the reaction [Formaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of IL6 protein] CTD PMID:22728154, PMID:27020608 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of ABCA1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CEBPA mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA; [Bexarotene co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [Copper co-treated with Ascorbic Acid] results in increased oxidation of and affects the folding of INS protein; [diazepinylbenzoic acid co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in decreased expression of ABCA1 mRNA; [LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [Rosiglitazone co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; [TO-901317 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA; [tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 protein; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; Bexarotene inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; Bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[LG 100268 co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; diazepinylbenzoic acid inhibits the reaction [[tributyltin co-treated with [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein]] results in increased expression of ABCA1 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of DMP1 mRNA]; tributyltin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SREBF1 mRNA]; Trientine inhibits the reaction [[Copper co-treated with Ascorbic Acid] results in increased oxidation of and affects the folding of INS protein]
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Allethrins inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; d,d-T80-prallethrin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; d,d-T80-prallethrin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; quinoxyfen inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; tetrabromobisphenol A inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; triphenyltin hydroxide inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]
CTD PMID:23403016, PMID:25932594, PMID:32473317 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Insr insulin receptor multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of INSR mRNA] CTD PMID:21911000 NCBI chr12:1,682,527...1,816,414
Ensembl chr12:1,680,957...1,816,414
JBrowse link
G Ireb2 iron responsive element binding protein 2 multiple interactions ISO [Ascorbic Acid co-treated with CAT protein] inhibits the reaction [Zinc deficiency results in increased expression of IREB2 protein] CTD PMID:18073202 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of IRS1 protein]; [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in decreased phosphorylation of IRS1 protein] CTD PMID:21911000 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Isl1 ISL LIM homeobox 1 increases expression ISO Ascorbic Acid results in increased expression of ISL1 mRNA CTD PMID:15305145 NCBI chr 2:48,488,911...48,501,217
Ensembl chr 2:48,487,736...48,501,436
JBrowse link
G Jag1 jagged canonical Notch ligand 1 decreases expression ISO Ascorbic Acid results in decreased expression of JAG1 mRNA CTD PMID:15305145 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of KCNB1 mRNA CTD PMID:16443354 NCBI chr 3:163,850,785...163,935,610
Ensembl chr 3:163,850,785...163,935,617
JBrowse link
G Kdm3a lysine demethylase 3A multiple interactions ISO Ascorbic Acid inhibits the reaction [nickel chloride results in increased expression of KDM3A mRNA]; Ascorbic Acid inhibits the reaction [nickel chloride results in increased expression of KDM3A protein] CTD PMID:22318714 NCBI chr 4:99,503,160...99,547,315
Ensembl chr 4:99,503,176...99,546,905
JBrowse link
G Kdr kinase insert domain receptor decreases expression ISO Ascorbic Acid results in decreased expression of KDR mRNA CTD PMID:21919647 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions
ISO Ascorbic Acid results in decreased expression of KEAP1 protein
Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of KEAP1 protein]
CTD PMID:31610155 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Kidins220 kinase D-interacting substrate 220 decreases expression EXP Ascorbic Acid results in decreased expression of KIDINS220 mRNA CTD PMID:15372504 NCBI chr 6:44,225,142...44,322,938
Ensembl chr 6:44,225,233...44,322,938
JBrowse link
G Kif1b kinesin family member 1B decreases expression EXP Ascorbic Acid results in decreased expression of KIF1B mRNA CTD PMID:15372504 NCBI chr 5:165,994,803...166,133,497
Ensembl chr 5:165,938,576...166,133,491
JBrowse link
G Kif1c kinesin family member 1C decreases expression EXP Ascorbic Acid results in decreased expression of KIF1C mRNA CTD PMID:15372504 NCBI chr10:57,322,259...57,352,395
Ensembl chr10:57,322,331...57,351,353
JBrowse link
G Kif23 kinesin family member 23 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of KIF23 mRNA CTD PMID:17639512 NCBI chr 8:66,866,043...66,893,241
Ensembl chr 8:66,866,082...66,893,196
JBrowse link
G Klrk1 killer cell lectin like receptor K1 decreases expression ISO Ascorbic Acid deficiency results in decreased expression of KLRK1 protein CTD PMID:22306178 NCBI chr 4:163,392,652...163,403,735
Ensembl chr 4:163,393,217...163,403,653
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO Ascorbic Acid inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of LCK protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased phosphorylation of LCK protein] CTD PMID:14572611 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Lep leptin decreases secretion
multiple interactions
EXP Ascorbic Acid results in decreased secretion of LEP protein
Ascorbic Acid inhibits the reaction [INS1 protein results in increased secretion of LEP protein]
CTD PMID:20400526 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lgals1 galectin 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of LGALS1 mRNA CTD PMID:17639512 NCBI chr 7:120,153,184...120,156,290
Ensembl chr 7:120,153,184...120,156,289
JBrowse link
G Lgals3 galectin 3 increases expression EXP Ascorbic Acid results in increased expression of LGALS3 mRNA CTD PMID:15372504 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of LHB protein] CTD PMID:16248992, PMID:16298753, PMID:17280759 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of LHCGR mRNA] CTD PMID:18602937 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Loxl2 lysyl oxidase-like 2 decreases expression ISO Ascorbic Acid results in decreased expression of LOXL2 mRNA CTD PMID:19197388 NCBI chr15:51,276,022...51,365,238
Ensembl chr15:51,303,909...51,365,234
JBrowse link
G Lpar2 lysophosphatidic acid receptor 2 multiple interactions ISO Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in decreased methylation of LPAR2 promoter]; Ascorbic Acid inhibits the reaction [Benzo(a)pyrene results in increased expression of LPAR2 mRNA] CTD PMID:27901495 NCBI chr16:21,343,313...21,348,913
Ensembl chr16:21,344,456...21,348,391
JBrowse link
G Lxn latexin increases expression ISO Ascorbic Acid results in increased expression of LXN mRNA; Ascorbic Acid results in increased expression of LXN protein CTD PMID:22139585 NCBI chr 2:164,628,565...164,634,434
Ensembl chr 2:164,628,566...164,634,434
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO Ascorbic Acid inhibits the reaction [bis(2-hydroxy-2-ethylbutanoato)oxochromate(V) results in increased phosphorylation of LYN protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased phosphorylation of LYN protein] CTD PMID:14572611 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Maff MAF bZIP transcription factor F multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of MAFF mRNA CTD PMID:17639512 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 increases expression ISO Ascorbic Acid results in increased expression of MAGI2 mRNA CTD PMID:15305145 NCBI chr 4:10,995,241...12,472,423
Ensembl chr 4:10,995,234...11,610,518
JBrowse link
G Malt1 MALT1 paracaspase multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of MALT1 mRNA CTD PMID:17639512 NCBI chr18:61,108,712...61,162,446
Ensembl chr18:61,109,069...61,162,445
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression EXP Ascorbic Acid results in decreased expression of MAP2 protein CTD PMID:15372504 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 multiple interactions ISO Ascorbic Acid inhibits the reaction [Fenretinide results in increased phosphorylation of MAP2K3 protein] CTD PMID:16407847 NCBI chr10:45,089,455...45,110,802
Ensembl chr10:47,182,433...47,203,753
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO Ascorbic Acid inhibits the reaction [Fenretinide results in increased phosphorylation of MAP2K6 protein] CTD PMID:16407847 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 multiple interactions ISO Ascorbic Acid inhibits the reaction [Plant Extracts results in increased phosphorylation of MAP3K5 protein] CTD PMID:20206247 NCBI chr 1:15,412,603...15,613,752
Ensembl chr 1:15,412,603...15,613,746
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
U 0126 inhibits the reaction [Ascorbic Acid results in increased phosphorylation of MAPK1 protein]
[juglone co-treated with Ascorbic Acid] results in decreased phosphorylation of MAPK1 protein
Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased phosphorylation of MAPK1 protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased phosphorylation of MAPK1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of MAPK1 protein modified form]
CTD PMID:20530736, PMID:21262251, PMID:22728154, PMID:29992683, PMID:31585129 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Ascorbic Acid inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK14 protein] CTD PMID:16407847 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
U 0126 inhibits the reaction [Ascorbic Acid results in increased phosphorylation of MAPK3 protein]
[juglone co-treated with Ascorbic Acid] results in decreased phosphorylation of MAPK3 protein
Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased phosphorylation of MAPK3 protein]; Ascorbic Acid inhibits the reaction [lead acetate results in increased phosphorylation of MAPK3 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate affects the localization of MAPK3 protein modified form]
CTD PMID:20530736, PMID:21262251, PMID:22728154, PMID:29992683, PMID:31585129 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein; Ascorbic Acid inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK8 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK8 protein] CTD PMID:20206247, PMID:24488945 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK9 protein; Ascorbic Acid inhibits the reaction [Plant Extracts results in increased phosphorylation of MAPK9 protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with Eosine I Bluish] results in increased phosphorylation of MAPK9 protein] CTD PMID:20206247, PMID:24488945 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapt microtubule-associated protein tau multiple interactions EXP Ascorbic Acid inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein] CTD PMID:24142891 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mcm4 minichromosome maintenance complex component 4 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of MCM4 mRNA CTD PMID:17639512 NCBI chr11:89,511,191...89,524,892
Ensembl chr11:89,511,191...89,524,892
JBrowse link
G Mdk midkine increases expression EXP Ascorbic Acid results in increased expression of MDK mRNA CTD PMID:15372504 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions EXP Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of MDM2 protein] CTD PMID:21262251 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mep1a meprin A subunit alpha multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of MEP1A mRNA CTD PMID:17639512 NCBI chr 9:20,048,163...20,077,678
Ensembl chr 9:20,048,121...20,077,702
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression ISO Ascorbic Acid results in decreased expression of MET mRNA CTD PMID:21919647 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions EXP Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA] CTD PMID:18544905 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression EXP Ascorbic Acid results in increased expression of MGST1 mRNA CTD PMID:15372504 NCBI chr 4:172,119,382...172,134,609
Ensembl chr 4:172,119,331...172,134,607
JBrowse link
G Mir93 microRNA 93 multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [Estradiol results in increased expression of MIR93 mRNA] CTD PMID:23492819 NCBI chr12:19,307,543...19,307,629
Ensembl chr12:19,307,543...19,307,629
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions ISO
EXP
[Quercetin co-treated with Ascorbic Acid] results in increased expression of MKI67 mRNA
[alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of MKI67 mRNA
CTD PMID:17639512, PMID:23859036 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mlh1 mutL homolog 1 multiple interactions ISO Ascorbic Acid promotes the reaction [MLH1 gene mutant form results in decreased susceptibility to chromium hexavalent ion]; MLH1 protein promotes the reaction [Ascorbic Acid results in increased susceptibility to chromium hexavalent ion]; MLH1 protein results in increased susceptibility to [chromium hexavalent ion co-treated with Ascorbic Acid] CTD PMID:15831465, PMID:17169990, PMID:17301063 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [Tobacco Smoke Pollution results in increased expression of MMP1 mRNA] CTD PMID:10836612 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 mRNA; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MMP13 protein]
[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in decreased expression of MMP13 mRNA; IL1B protein inhibits the reaction [[TGFB3 protein co-treated with Ascorbic Acid co-treated with Dexamethasone] results in decreased expression of MMP13 mRNA]
CTD PMID:23692848, PMID:26526931 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [Cyclosporine results in increased expression of MMP2 protein]
[juglone co-treated with Ascorbic Acid] affects the expression of MMP2 mRNA
CTD PMID:19391111, PMID:29992683 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp7 matrix metallopeptidase 7 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of MMP7 mRNA CTD PMID:17639512 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO [juglone co-treated with Ascorbic Acid] results in decreased expression of MMP9 mRNA CTD PMID:29992683 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP
ISO
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein]; Ascorbic Acid inhibits the reaction [Formaldehyde inhibits the reaction [Lipopolysaccharides results in increased expression of MPO protein]]; Ascorbic Acid inhibits the reaction [Indomethacin results in increased activity of MPO protein]
Ascorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Albuterol]; Ascorbic Acid inhibits the reaction [[MPO protein co-treated with Hydrogen Peroxide] results in increased oxidation of Fenoterol]
CTD PMID:18726076, PMID:19462961, PMID:27020608, PMID:31022331 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Msh2 mutS homolog 2 multiple interactions ISO MSH2 protein promotes the reaction [Ascorbic Acid results in increased susceptibility to chromium hexavalent ion]; MSH2 protein results in increased susceptibility to [chromium hexavalent ion co-treated with Ascorbic Acid] CTD PMID:17169990, PMID:17301063 NCBI chr 6:11,215,951...11,274,916
Ensembl chr 6:11,215,963...11,274,932
JBrowse link
G Mst1 macrophage stimulating 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of MST1 mRNA CTD PMID:17639512 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
JBrowse link
G Msx2 msh homeobox 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of MSX2 mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of MSX2 mRNA] CTD PMID:28189605 NCBI chr17:11,683,862...11,689,527
Ensembl chr17:11,683,862...11,689,527
JBrowse link
G Mt1 metallothionein 1 increases expression EXP Ascorbic Acid results in increased expression of MT1A mRNA CTD PMID:15372504 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt3 metallothionein 3 increases expression
multiple interactions
EXP
ISO
Ascorbic Acid results in increased expression of MT3 mRNA
[[MT3 protein binds to Zinc] which co-treated with Ascorbic Acid] inhibits the reaction [Copper results in increased chemical synthesis of Hydroxyl Radical]
CTD PMID:15372504, PMID:17389590 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase decreases expression ISO Ascorbic Acid results in decreased expression of MTHFD2 mRNA CTD PMID:19197388 NCBI chr 4:115,004,433...115,015,965
Ensembl chr 4:115,004,448...115,015,965
JBrowse link
G Myb MYB proto-oncogene, transcription factor multiple interactions EXP [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of MYB protein CTD PMID:7593635 NCBI chr 1:16,658,178...16,690,135
Ensembl chr 1:16,659,442...16,687,817
JBrowse link
G Mybl2 MYB proto-oncogene like 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of MYBL2 mRNA CTD PMID:17639512 NCBI chr 3:159,421,638...159,450,087
Ensembl chr 3:159,421,671...159,450,086
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO Ascorbic Acid inhibits the reaction [phenylhydrazine results in decreased expression of MYC mRNA] CTD PMID:30140404 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh11 myosin heavy chain 11 increases expression EXP Ascorbic Acid results in increased expression of MYH11 protein CTD PMID:14639096 NCBI chr10:764,421...859,184
Ensembl chr10:764,421...859,184
JBrowse link
G Myh6 myosin heavy chain 6 increases expression ISO Ascorbic Acid results in increased expression of MYH6 mRNA CTD PMID:12668514 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myh7 myosin heavy chain 7 increases expression ISO Ascorbic Acid results in increased expression of MYH7 mRNA CTD PMID:12668514, PMID:21570463 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089
JBrowse link
G Myl2 myosin light chain 2 increases expression ISO Ascorbic Acid results in increased expression of MYL2 mRNA CTD PMID:21570463 NCBI chr12:39,951,863...39,959,065
Ensembl chr12:39,951,987...39,958,239
JBrowse link
G Myo1a myosin IA multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of MYO1A mRNA CTD PMID:17639512 NCBI chr 7:71,000,299...71,019,386
Ensembl chr 7:71,004,417...71,019,372
JBrowse link
G Myo1e myosin IE decreases expression EXP Ascorbic Acid results in decreased expression of MYO1E mRNA CTD PMID:15372504 NCBI chr 8:76,644,715...76,840,240
Ensembl chr 8:76,754,492...76,839,593
JBrowse link
G Nampt nicotinamide phosphoribosyltransferase multiple interactions EXP [Ascorbic Acid co-treated with INS1 protein] results in increased expression of NAMPT mRNA CTD PMID:20400526 NCBI chr 6:52,122,085...52,156,473
Ensembl chr 6:52,122,085...52,156,472
JBrowse link
G Nars1 asparaginyl-tRNA synthetase 1 decreases expression ISO Ascorbic Acid results in decreased expression of NARS1 mRNA CTD PMID:19197388 NCBI chr18:59,986,350...60,002,644
Ensembl chr18:59,986,360...60,002,569
JBrowse link
G Ncald neurocalcin delta increases expression ISO Ascorbic Acid results in increased expression of NCALD mRNA CTD PMID:15305145 NCBI chr 7:76,199,305...76,632,847
Ensembl chr 7:76,199,306...76,488,216
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of NDRG1 protein] CTD PMID:16288478 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Ndrg2 NDRG family member 2 increases expression EXP Ascorbic Acid results in increased expression of NDRG2 mRNA CTD PMID:15372504 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459
JBrowse link
G Nes nestin decreases expression EXP Ascorbic Acid results in decreased expression of NES protein CTD PMID:15372504 NCBI chr 2:187,343,109...187,352,972
Ensembl chr 2:187,344,056...187,352,969
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 increases expression ISO Ascorbic Acid results in increased expression of NFE2L1 mRNA; Ascorbic Acid results in increased expression of NFE2L1 protein CTD PMID:25130429 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions
increases expression
affects localization
ISO
EXP
[lead acetate results in increased abundance of Lead] inhibits the reaction [Ascorbic Acid results in increased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Resveratrol results in increased activity of NFE2L2 promoter]; Ascorbic Acid promotes the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of NFE2L2 mRNA]
Ascorbic Acid results in increased expression of NFE2L2 mRNA; Ascorbic Acid results in increased expression of NFE2L2 protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Estradiol affects the localization of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Estradiol inhibits the reaction [NFE2L2 protein binds to SOD3 promoter]]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NFE2L2 protein]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of NFE2L2 mRNA]; Ascorbic Acid inhibits the reaction [Ethylene Chlorohydrin results in increased expression of NFE2L2 protein]; Ascorbic Acid promotes the reaction [Cadmium results in increased expression of NFE2L2 protein]
Ascorbic Acid affects the localization of NFE2L2 protein
CTD PMID:21199573, PMID:22008531, PMID:23027624, PMID:23492819, PMID:25130429, PMID:29663635, PMID:29940330, PMID:31585129, PMID:31610155 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfe2l3 nuclear factor, erythroid 2-like 3 decreases expression ISO Ascorbic Acid results in decreased expression of NFE2L3 mRNA; Ascorbic Acid results in decreased expression of NFE2L3 protein CTD PMID:25130429 NCBI chr 4:81,205,214...81,233,068
Ensembl chr 4:81,205,404...81,232,813
JBrowse link
G Nfib nuclear factor I/B increases expression ISO Ascorbic Acid results in increased expression of NFIB mRNA CTD PMID:15305145 NCBI chr 5:100,436,343...100,647,962
Ensembl chr 5:100,439,082...100,647,727
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]
[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of NFKB1 protein; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of NFKB1 protein]; Ascorbic Acid inhibits the reaction [Norepinephrine affects the localization of NFKB1 protein]
CTD PMID:17879260, PMID:23114885, PMID:23692848 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Ascorbic Acid co-treated with ferrous sulfate] results in decreased expression of NFKBIA protein; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA]; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in decreased expression of NFKBIA protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased degradation of NFKBIA protein]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of NFKBIA mRNA] CTD PMID:17879260, PMID:25305479, PMID:25551565 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfya nuclear transcription factor Y subunit alpha multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NFYA mRNA CTD PMID:16443354 NCBI chr 9:14,551,752...14,577,002
Ensembl chr 9:14,551,758...14,576,967
JBrowse link
G Ninj1 ninjurin 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NINJ1 mRNA CTD PMID:16443354 NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327
JBrowse link
G Nkx2-1 NK2 homeobox 1 multiple interactions ISO
EXP
Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of NKX2-1 mRNA]; Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of NKX2-1 protein] CTD PMID:15083329, PMID:16863852 NCBI chr 6:77,418,096...77,423,383
Ensembl chr 6:77,418,096...77,421,286
JBrowse link
G Nkx2-5 NK2 homeobox 5 increases expression ISO Ascorbic Acid results in increased expression of NKX2-5 mRNA CTD PMID:12668514 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of NME1 mRNA CTD PMID:16443354 NCBI chr10:81,657,152...81,666,542
Ensembl chr10:81,657,153...81,666,523
JBrowse link
G Nnat neuronatin increases expression ISO Ascorbic Acid results in increased expression of NNAT mRNA CTD PMID:15305145 NCBI chr 3:154,043,873...154,046,334
Ensembl chr 3:154,043,873...154,046,330
JBrowse link
G Nog noggin multiple interactions EXP NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMP2 protein]]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of BMPR1A protein]]]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]] CTD PMID:27387537 NCBI chr10:76,811,759...76,813,386
Ensembl chr10:76,811,759...76,813,386
JBrowse link
G Nos2 nitric oxide synthase 2 increases activity
multiple interactions
decreases expression
ISO
EXP
Ascorbic Acid results in increased activity of NOS2 protein
[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 mRNA; [Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 protein; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 mRNA]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 mRNA]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased expression of NOS2 protein]
Ascorbic Acid results in decreased expression of NOS2
[Ascorbic Acid co-treated with Formaldehyde] results in decreased expression of NOS2 mRNA; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Ascorbic Acid inhibits the reaction [Cyclosporine results in increased expression of NOS2 protein]; Ascorbic Acid inhibits the reaction [endotoxin, Escherichia coli results in increased expression of NOS2 protein]; Ascorbic Acid inhibits the reaction [Isoproterenol results in increased expression of NOS2 protein]; Ascorbic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Ascorbic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Ascorbic Acid inhibits the reaction [nickel sulfate results in increased activity of NOS2 protein]
Ascorbic Acid inhibits the reaction [Aspirin results in increased expression of NOS2 protein]
CTD PMID:15612528, PMID:17218764, PMID:17637181, PMID:18779489, PMID:19391111, PMID:19466570, PMID:19494560, PMID:20179380, PMID:23463385, PMID:23692848, PMID:27020608 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
[Isosorbide Dinitrate co-treated with Ascorbic Acid] affects the expression of NOS3 mRNA
Ascorbic Acid results in increased activity of NOS3 protein
[Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dexamethasone results in decreased expression of NOS3 protein]; Ascorbic Acid inhibits the reaction [Formaldehyde results in decreased expression of NOS3 mRNA]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of NOS3 protein]
Ascorbic Acid results in increased phosphorylation of NOS3 protein
CTD PMID:11243424, PMID:11729227, PMID:15719745, PMID:20068362, PMID:21570463, PMID:27020608 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Nox1 NADPH oxidase 1 increases expression ISO Ascorbic Acid results in increased expression of NOX1 protein CTD PMID:21570463 NCBI chr  X:104,909,328...104,932,508
Ensembl chr  X:104,909,326...104,932,508
JBrowse link
G Nox4 NADPH oxidase 4 increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of NOX4 mRNA; Ascorbic Acid results in increased expression of NOX4 protein
Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of NOX4 mRNA]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of NOX4 protein]
CTD PMID:21570463, PMID:25305479 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Npm1 nucleophosmin 1 increases expression ISO Ascorbic Acid results in increased expression of NPM1 mRNA CTD PMID:22139585 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO
EXP
Ascorbic Acid promotes the reaction [sodium arsenite results in increased expression of NQO1 mRNA]
Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of NQO1 mRNA]; Ascorbic Acid inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NQO1 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NQO1 mRNA]; Ascorbic Acid inhibits the reaction [Estradiol results in decreased expression of NQO1 protein]
Ascorbic Acid results in increased expression of NQO1 protein
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate results in increased expression of NQO1 protein]; Ascorbic Acid promotes the reaction [Cadmium results in increased expression of NQO1 protein]
CTD PMID:16517059, PMID:22008531, PMID:25130429, PMID:29663635, PMID:31610155, PMID:32525552 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA; bexarotene promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA]; tributyltin promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of NR1H3 mRNA] CTD PMID:25932594 NCBI chr 3:80,004,130...80,014,197
Ensembl chr 3:80,004,130...80,012,750
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of NR3C1 mRNA CTD PMID:16443354 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of NR4A3 mRNA CTD PMID:16443354 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of NR5A1 mRNA] CTD PMID:18602937 NCBI chr 3:22,998,900...23,020,441
Ensembl chr 3:22,999,616...23,020,441
JBrowse link
G Nrep neuronal regeneration related protein increases expression ISO Ascorbic Acid results in increased expression of NREP mRNA CTD PMID:15305145 NCBI chr18:26,183,753...26,212,796
Ensembl chr18:26,185,259...26,211,445
JBrowse link
G Nrxn1 neurexin 1 decreases expression EXP Ascorbic Acid results in decreased expression of NRXN1 mRNA CTD PMID:15372504 NCBI chr 6:13,886,757...15,191,660
Ensembl chr 6:13,886,740...15,191,660
JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of NSD2 mRNA CTD PMID:26424790 NCBI chr14:82,119,210...82,196,501
Ensembl chr14:82,119,210...82,171,480
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 increases expression ISO Ascorbic Acid results in increased expression of NTRK2 mRNA CTD PMID:15305145 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Ocln occludin multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [mono-(2-ethylhexyl)phthalate affects the localization of OCLN protein] CTD PMID:29940330 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Ogdh oxoglutarate dehydrogenase multiple interactions EXP Ascorbic Acid inhibits the reaction [Arsenic results in decreased activity of OGDH protein]; Ascorbic Acid inhibits the reaction [sodium arsenite results in decreased activity of OGDH protein] CTD PMID:12915223, PMID:24295472 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Ogfod1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 multiple interactions
decreases expression
ISO [arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of OGFOD1 mRNA
Ascorbic Acid results in decreased expression of OGFOD1 mRNA
CTD PMID:25555879 NCBI chr19:11,425,301...11,451,085
Ensembl chr19:11,425,105...11,451,278
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of OLR1 mRNA CTD PMID:17639512 NCBI chr 4:163,239,853...163,261,937
Ensembl chr 4:163,239,849...163,261,958
JBrowse link
G Os9 OS9, endoplasmic reticulum lectin multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of OS9 mRNA CTD PMID:16443354 NCBI chr 7:70,378,625...70,407,135
Ensembl chr 7:70,380,311...70,407,177
JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 decreases expression ISO Ascorbic Acid results in decreased expression of P4HA2 mRNA CTD PMID:19197388 NCBI chr10:39,435,227...39,464,134
Ensembl chr10:39,435,227...39,464,188
JBrowse link
G P4htm prolyl 4-hydroxylase, transmembrane multiple interactions ISO [Ketoglutaric Acids co-treated with Ascorbic Acid co-treated with ferrous chloride] results in increased activity of P4HTM protein CTD PMID:19263519 NCBI chr 8:117,364,895...117,383,275
Ensembl chr 8:117,365,101...117,382,715
JBrowse link
G Papss1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 decreases expression
multiple interactions
ISO Ascorbic Acid results in decreased expression of PAPSS1 mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of PAPSS1 mRNA
CTD PMID:25555879 NCBI chr 2:236,605,695...236,680,772
Ensembl chr 2:236,605,695...236,680,772
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP
ISO
Ascorbic Acid inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]; Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased cleavage of PARP1 protein]
[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of PARP1 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of PARP1 mRNA]
[juglone co-treated with Ascorbic Acid] results in increased degradation of PARP1 protein; Ascorbic Acid inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]; Ascorbic Acid inhibits the reaction [Oleanolic Acid results in increased cleavage of PARP1 protein]; Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein]
CTD PMID:16407847, PMID:17301063, PMID:19433269, PMID:21262251, PMID:22678527, PMID:26492236, PMID:29992683 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) decreases expression ISO Ascorbic Acid results in decreased expression of PCK2 mRNA CTD PMID:19197388 NCBI chr15:34,216,735...34,224,357
Ensembl chr15:34,216,833...34,224,193
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO
EXP
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of PCNA protein
[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of PCNA protein; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of PCNA protein]
CTD PMID:17917374, PMID:18544905, PMID:21621607 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pcp4 Purkinje cell protein 4 increases expression EXP Ascorbic Acid results in increased expression of PCP4 mRNA CTD PMID:15372504 NCBI chr11:36,851,035...36,912,272
Ensembl chr11:36,851,038...36,912,229
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB mRNA; [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB protein CTD PMID:23859036 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 decreases expression ISO Ascorbic Acid results in decreased expression of PDIA2 mRNA CTD PMID:19197388
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions ISO Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of PDIA3 mRNA]; Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of PDIA3 protein] CTD PMID:17353921 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 increases expression ISO Ascorbic Acid results in increased expression of PEBP1 mRNA; Ascorbic Acid results in increased expression of PEBP1 protein CTD PMID:19224539 NCBI chr12:45,026,948...45,031,148
Ensembl chr12:45,026,886...45,031,145
JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase multiple interactions
increases expression
ISO [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of PFAS mRNA
Ascorbic Acid results in increased expression of PFAS mRNA
CTD PMID:25555879 NCBI chr10:55,571,881...55,593,384
Ensembl chr10:55,571,118...55,589,978
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [Iodoacetamide affects the activity of PFKFB1 protein] CTD PMID:6092364 NCBI chr  X:23,092,143...23,145,923
Ensembl chr  X:23,092,159...23,144,324
JBrowse link
G Phf2 PHD finger protein 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of PHF2 mRNA CTD PMID:26424790 NCBI chr17:16,240,458...16,274,626
Ensembl chr17:16,204,427...16,274,624
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Ascorbic Acid results in decreased expression of PHGDH mRNA CTD PMID:19197388 NCBI chr 2:200,484,245...200,513,564
Ensembl chr 2:200,484,246...200,513,564
JBrowse link
G Phlda1 pleckstrin homology-like domain, family A, member 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of PHLDA1 mRNA CTD PMID:17639512 NCBI chr 7:54,247,460...54,249,664
Ensembl chr 7:54,247,460...54,249,664
JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of PHLDA2 mRNA CTD PMID:17639512 NCBI chr 1:216,701,345...216,704,479
Ensembl chr 1:216,702,319...216,703,534
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression EXP Ascorbic Acid results in decreased expression of PIK3R1 mRNA CTD PMID:15372504 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pkm pyruvate kinase M1/2 increases expression ISO Ascorbic Acid results in increased expression of PKM mRNA CTD PMID:22139585 NCBI chr 8:64,480,963...64,502,957
Ensembl chr 8:64,481,172...64,502,722
JBrowse link
G Plaat3 phospholipase A and acyltransferase 3 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of PLAAT3 mRNA CTD PMID:17639512 NCBI chr 1:222,844,238...222,877,180
Ensembl chr 1:222,844,144...222,877,193
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Endosulfan results in increased activity of PLAT protein]; Ascorbic Acid promotes the reaction [Vitamin E results in increased activity of PLAT protein] CTD PMID:21804306 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plg plasminogen multiple interactions ISO Ascorbic Acid inhibits the reaction [Arsenic promotes the reaction [Humic Substances results in decreased activity of PLG protein]]; Ascorbic Acid inhibits the reaction [Humic Substances results in decreased activity of PLG protein] CTD PMID:11419606 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Plin1 perilipin 1 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; tetrabromobisphenol A promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; triphenyltin hydroxide promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]
CTD PMID:25932594, PMID:32473317 NCBI chr 1:141,458,907...141,470,927
Ensembl chr 1:141,458,181...141,471,010
JBrowse link
G Plk1 polo-like kinase 1 multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of PLK1 mRNA CTD PMID:17639512 NCBI chr 1:192,115,990...192,125,969
Ensembl chr 1:192,115,966...192,125,989
JBrowse link
G Plk2 polo-like kinase 2 decreases expression EXP Ascorbic Acid results in decreased expression of PLK2 mRNA CTD PMID:15372504 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Pls3 plastin 3 increases expression ISO Ascorbic Acid results in increased expression of PLS3 mRNA; Ascorbic Acid results in increased expression of PLS3 protein CTD PMID:22139585 NCBI chr  X:119,030,311...119,124,268
Ensembl chr  X:119,030,419...119,124,250
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 multiple interactions ISO Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of PMAIP1 mRNA] CTD PMID:17216584 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Pmp22 peripheral myelin protein 22 decreases expression
multiple interactions
ISO Ascorbic Acid results in decreased expression of PMP22 mRNA
Ascorbic Acid inhibits the reaction [Bucladesine results in increased activity of PMP22 promoter]
CTD PMID:15034573, PMID:17303424 NCBI chr10:49,538,588...49,568,583
Ensembl chr10:49,538,588...49,568,583
JBrowse link
G Pnp purine nucleoside phosphorylase affects expression ISO Ascorbic Acid affects the expression of PNP protein CTD PMID:19224539 NCBI chr15:27,875,883...27,883,566
Ensembl chr15:27,875,911...27,883,350
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity
EXP
ISO
[Iron co-treated with Ascorbic Acid] results in decreased activity of PON1 protein; [Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein
Ascorbic Acid results in decreased activity of PON1 protein
1,2-dioleoyl-sn-glycero-3-phosphoglycerol inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; 1,2-dioleoyl-sn-glycero-3-phosphoglycerol inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; 1,2-dipalmitoylphosphatidylglycerol inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; 1,2-oleoylphosphatidylcholine inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; [Ascorbic Acid co-treated with Copper Sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; [Ascorbic Acid co-treated with Copper Sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]; [Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein; [Ascorbic Acid co-treated with ferrous sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; [Ascorbic Acid co-treated with ferrous sulfate] inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]; [Ascorbic Acid co-treated with ferrous sulfate] results in decreased activity of PON1 protein; [Iron co-treated with Ascorbic Acid] results in decreased activity of PON1 protein; [Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein; [PON1 protein results in increased metabolism of [Acrolein binds to Ascorbic Acid]] which results in increased chemical synthesis of 5,6,7,8-tetrahydroxy-4-oxooctanal; Butylated Hydroxytoluene inhibits the reaction [[Iron co-treated with Ascorbic Acid] results in decreased expression of PON1 protein]; CAT protein inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]; erucic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; Hypochlorous Acid promotes the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; Oleic Acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; palmitoleic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; PON1 protein results in increased metabolism of [Acrolein binds to Ascorbic Acid]; Sulfhydryl Compounds inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]
CTD PMID:12871208, PMID:15104111, PMID:15375178, PMID:16052486, PMID:20353174 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Pon2 paraoxonase 2 multiple interactions ISO [PON2 protein results in increased metabolism of [Acrolein binds to Ascorbic Acid]] which results in increased chemical synthesis of 5,6,7,8-tetrahydroxy-4-oxooctanal; PON2 protein results in increased metabolism of [Acrolein binds to Ascorbic Acid] CTD PMID:20353174 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression
multiple interactions
ISO Ascorbic Acid results in increased expression of POU5F1 mRNA
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in decreased expression of POU5F1 mRNA
Ascorbic Acid inhibits the reaction [Cobalt results in increased expression of POU5F1 protein]
CTD PMID:21166886, PMID:24497960, PMID:28189605 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA; [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA; Rosiglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA]; SRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]]; Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of PPARG mRNA]; Tretinoin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PPARG mRNA] CTD PMID:14505802, PMID:25932594, PMID:32473317 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Ascorbic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Pprc1 PPARG related coactivator 1 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid] results in increased expression of PPRC1 mRNA CTD PMID:25555879 NCBI chr 1:265,809,892...265,826,319
Ensembl chr 1:265,809,754...265,826,306
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions EXP [Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PRDX1 mRNA CTD PMID:18544905 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions EXP Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of PRDX3 mRNA] CTD PMID:23470461 NCBI chr 1:282,238,774...282,251,193
Ensembl chr 1:282,238,773...282,251,257
JBrowse link
G Prf1 perforin 1 decreases expression ISO Ascorbic Acid deficiency results in decreased expression of PRF1 mRNA CTD PMID:22306178 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Prkcb protein kinase C, beta increases expression ISO Ascorbic Acid results in increased expression of PRKCB mRNA CTD PMID:15305145 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkcq protein kinase C, theta multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of PRKCQ mRNA CTD PMID:16443354 NCBI chr17:70,971,915...71,105,286
Ensembl chr17:70,971,915...71,105,286
JBrowse link
G Prl prolactin multiple interactions EXP Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of PRL protein]; Ascorbic Acid inhibits the reaction [chromium hexavalent ion results in decreased expression of PRL protein] CTD PMID:16298753, PMID:18602937 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Pros1 protein S decreases expression EXP Ascorbic Acid results in decreased expression of PROS1 mRNA CTD PMID:15372504 NCBI chr 7:1,206,648...1,288,140
Ensembl chr 7:1,206,648...1,288,134
JBrowse link
G Psmb6 proteasome 20S subunit beta 6 multiple interactions ISO Ascorbic Acid inhibits the reaction [epoxomicin results in increased expression of PSMB6 mRNA]; Ascorbic Acid inhibits the reaction [Rotenone results in increased expression of PSMB6 mRNA] CTD PMID:27345029 NCBI chr10:57,131,339...57,133,685
Ensembl chr10:57,131,386...57,133,637
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of PSMC3 mRNA CTD PMID:16443354 NCBI chr 3:79,876,938...79,882,319
Ensembl chr 3:79,876,938...79,882,319
JBrowse link
G Psme2 proteasome activator subunit 2 increases expression ISO Ascorbic Acid results in increased expression of PSME2 mRNA; Ascorbic Acid results in increased expression of PSME2 protein CTD PMID:22139585 NCBI chr15:34,265,552...34,269,851
Ensembl chr15:34,265,557...34,269,851
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [Formaldehyde results in increased expression of PTGS1 mRNA] CTD PMID:27020608 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
[juglone co-treated with Ascorbic Acid] results in decreased expression of PTGS2 mRNA; Ascorbic Acid inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of PTGS2 mRNA]; Ascorbic Acid inhibits the reaction [Aspirin results in increased expression of PTGS2 mRNA]
[Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 protein; Ascorbic Acid inhibits the reaction [[sodium bisulfite co-treated with sodium sulfite] results in increased expression of PTGS2 protein]; Ascorbic Acid inhibits the reaction [endotoxin, Escherichia coli results in increased expression of PTGS2 protein]; Ascorbic Acid inhibits the reaction [Formaldehyde results in increased expression of PTGS2 mRNA]; Ascorbic Acid inhibits the reaction [lead acetate results in increased expression of PTGS2 protein]; Ascorbic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
[Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 mRNA; [Quartz co-treated with Ascorbic Acid] results in increased expression of PTGS2 protein; Ascorbic Acid inhibits the reaction [JP8 aviation fuel results in increased expression of PTGS2 mRNA]
CTD PMID:17218764, PMID:17222177, PMID:17637181, PMID:19095747, PMID:21873648, PMID:22728154, PMID:27020608, PMID:29992683, PMID:32525552 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Pth1r parathyroid hormone 1 receptor multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of PTH1R mRNA; cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of PTH1R mRNA] CTD PMID:28189605 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Pthlh parathyroid hormone-like hormone decreases expression EXP Ascorbic Acid results in decreased expression of PTHLH mRNA CTD PMID:15372504 NCBI chr 4:181,663,425...181,674,181 JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression EXP Ascorbic Acid results in decreased expression of PTK2 mRNA CTD PMID:15372504 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Ptn pleiotrophin increases expression ISO Ascorbic Acid results in increased expression of PTN mRNA CTD PMID:15305145 NCBI chr 4:64,239,156...64,330,996
Ensembl chr 4:64,239,158...64,330,996
JBrowse link
G Pvalb parvalbumin multiple interactions EXP Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of PVALB protein] CTD PMID:31708536 NCBI chr 7:119,428,657...119,443,674
Ensembl chr 7:119,429,019...119,441,487
JBrowse link
G Rab3b RAB3B, member RAS oncogene family multiple interactions
increases expression
ISO
EXP
[Quercetin co-treated with Ascorbic Acid] results in increased expression of RAB3B mRNA
Ascorbic Acid results in increased expression of RAB3B mRNA
CTD PMID:15372504, PMID:17639512 NCBI chr 5:128,501,789...128,568,170
Ensembl chr 5:128,501,847...128,568,188
JBrowse link
G Rab6a RAB6A, member RAS oncogene family multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in decreased expression of RAB6A mRNA CTD PMID:16443354 NCBI chr 1:165,624,973...165,664,201
Ensembl chr 1:165,625,058...165,664,192
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO Ascorbic Acid promotes the reaction [arsenic trioxide results in increased activity of RAC1 protein] CTD PMID:12239215 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rad50 RAD50 double strand break repair protein multiple interactions ISO [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of RAD50 mRNA CTD PMID:17917374 NCBI chr10:39,002,130...39,054,042
Ensembl chr10:39,001,498...39,054,142
JBrowse link
G Rad51c RAD51 paralog C multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of RAD51C mRNA CTD PMID:16443354 NCBI chr10:74,697,713...74,724,004
Ensembl chr10:74,697,716...74,724,472
JBrowse link
G Rad54b RAD54 homolog B multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in increased expression of RAD54B mRNA CTD PMID:17639512 NCBI chr 5:25,140,531...25,214,469
Ensembl chr 5:25,146,949...25,214,376
JBrowse link
G Ran RAN, member RAS oncogene family increases expression ISO Ascorbic Acid results in increased expression of RAN mRNA; Ascorbic Acid results in increased expression of RAN protein CTD PMID:22139585 NCBI chr12:31,319,556...31,324,105
Ensembl chr12:31,320,624...31,323,810
JBrowse link
G Rcan1 regulator of calcineurin 1 multiple interactions ISO [Tretinoin co-treated with Ascorbic Acid] results in increased expression of RCAN1 mRNA CTD PMID:16443354 NCBI chr11:32,539,689...32,620,274
Ensembl chr11:32,539,683...32,550,539
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO Ascorbic Acid inhibits the reaction [Norepinephrine affects the localization of REL protein] CTD PMID:23114885 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO
EXP
[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]; CAT protein inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of [NFKB1 protein binds to RELA protein]]
Ascorbic Acid inhibits the reaction [Cyclosporine results in increased expression of RELA protein]; Ascorbic Acid inhibits the reaction [lead acetate affects the localization of RELA protein]
[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of RELA protein; [Hyaluronic Acid co-treated with Chondroitin Sulfates] inhibits the reaction [[Ascorbic Acid co-treated with ferrous sulfate] results in increased activity of RELA protein]; Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and affects the localization of RELA protein]; Ascorbic Acid inhibits the reaction [Norepinephrine affects the localization of RELA protein]
CTD PMID:17879260, PMID:19391111, PMID:22728154, PMID:23114885, PMID:23692848, PMID:25305479 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G RGD1309534 similar to RIKEN cDNA 4931406C07 decreases expression
multiple interactions
ISO Ascorbic Acid results in decreased expression of C11ORF54 mRNA
[arsenic trioxide co-treated with Ascorbic Acid] results in decreased expression of C11ORF54 mRNA
CTD PMID:25555879 NCBI chr 8:13,838,549...13,861,120
Ensembl chr 8:13,838,572...13,861,212
JBrowse link
G Rgs8 regulator of G-protein signaling 8 decreases expression EXP Ascorbic Acid results in decreased expression of RGS8 mRNA CTD PMID:15372504 NCBI chr13:71,086,654...71,141,820
Ensembl chr13:71,086,745...71,141,075
JBrowse link
G Rph3a rabphilin 3A increases expression ISO Ascorbic Acid results in increased expression of RPH3A mRNA CTD PMID:15305145 NCBI chr12:41,073,296...41,149,799
Ensembl chr12:41,073,824...41,148,490
JBrowse link
G Rps29 ribosomal protein S29 increases expression EXP Ascorbic Acid results in increased expression of RPS29 mRNA CTD PMID:15372504 NCBI chr 6:91,455,333...91,456,709
Ensembl chr 6:91,455,333...91,456,696
Ensembl chr 3:91,455,333...91,456,696
Ensembl chr 7:91,455,333...91,456,696
JBrowse link
G Rpsa ribosomal protein SA affects expression ISO Ascorbic Acid affects the expression of RPSA protein CTD PMID:19224539 NCBI chr 8:128,806,053...128,809,987
Ensembl chr 8:128,806,129...128,809,986
JBrowse link
G Runx2 RUNX family transcription factor 2 multiple interactions
increases expression
ISO
EXP
[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA; [Cholecalciferol co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] results in increased expression of RUNX2 mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]
Ascorbic Acid results in increased expression of RUNX2 mRNA
[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein; [Ascorbic Acid co-treated with Phosphates] results in increased expression of RUNX2 mRNA; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA; Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]; ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]; Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]; NOG protein inhibits the reaction [ginsenoside Rg3 inhibits the reaction [Dexamethasone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein]]]; Quercetin affects the reaction [Hydrogen Peroxide affects the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] affects the expression of RUNX2 mRNA]]
4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 protein]; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 mRNA; [[Dexamethasone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid] co-treated with fasudil] results in increased expression of RUNX2 protein; [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA; [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA; [Folic Acid co-treated with Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of RUNX2 mRNA]; Rosiglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of RUNX2 mRNA]; U 0126 inhibits the reaction [Ascorbic Acid results in increased expression of RUNX2 mRNA]
CTD PMID:17692823, PMID:20530736, PMID:21613385, PMID:26424790, PMID:26492236, PMID:27028516, PMID:27387537, PMID:28105418, PMID:31935364, PMID:32324263, PMID:32473317 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092
JBrowse link
G S100a10 S100 calcium binding protein A10 increases expression EXP Ascorbic Acid results in increased expression of S100A10 mRNA CTD PMID:15372504 NCBI chr 2:193,892,589...193,901,236
Ensembl chr 2:193,892,589...193,901,236
JBrowse link
G S100a4 S100 calcium-binding protein A4 multiple interactions ISO Ascorbic Acid inhibits the reaction [Copper promotes the reaction [S100A4 protein binds to S100A4 protein]] CTD PMID:21924240 NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression EXP Ascorbic Acid results in increased expression of S100A6 mRNA CTD PMID:15372504 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link
G S100b S100 calcium binding protein B increases expression EXP Ascorbic Acid results in increased expression of S100B mRNA CTD PMID:15372504 NCBI chr20:13,130,633...13,142,856
Ensembl chr20:13,130,636...13,142,856
JBrowse link
G S100g S100 calcium binding protein G multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of S100G mRNA CTD PMID:17639512 NCBI chr  X:33,442,820...33,445,714
Ensembl chr  X:33,443,186...33,445,709
JBrowse link
G Satb2 SATB homeobox 2 multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA; EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of SATB2 mRNA] CTD PMID:26424790 NCBI chr 9:63,456,877...63,642,193
Ensembl chr 9:63,456,783...63,641,400
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA; SRC protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA]]; Tetrachlorodibenzodioxin inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid] results in increased expression of SCD1 mRNA] CTD PMID:14505802 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sdc2 syndecan 2 decreases expression EXP Ascorbic Acid results in decreased expression of SDC2 mRNA CTD PMID:15372504 NCBI chr 7:71,572,731...71,686,139
Ensembl chr 7:71,572,941...71,686,044
JBrowse link
G Sdha succinate dehydrogenase complex flavoprotein subunit A multiple interactions ISO Ascorbic Acid inhibits the reaction [arsenic trioxide results in decreased expression of SDHA protein] CTD PMID:19422848 NCBI chr 1:31,545,631...31,570,601
Ensembl chr 1:31,545,631...31,570,601
JBrowse link
G Sec61g SEC61 translocon subunit gamma decreases expression EXP Ascorbic Acid results in decreased expression of SEC61G mRNA CTD PMID:15372504 NCBI chr14:99,774,589...99,780,964
Ensembl chr14:99,774,589...99,780,964
JBrowse link
G Sele selectin E multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of SELE mRNA]; Ascorbic Acid inhibits the reaction [TNF protein results in increased expression of SELE mRNA] CTD PMID:25551565 NCBI chr13:82,355,234...82,365,323
Ensembl chr13:82,355,471...82,365,341
JBrowse link
G Serpinb2 serpin family B member 2 decreases expression ISO Ascorbic Acid results in decreased expression of SERPINB2 mRNA CTD PMID:19197388 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP Ascorbic Acid promotes the reaction [Vitamin E inhibits the reaction [Endosulfan results in increased activity of SERPINE1 protein]] CTD PMID:21804306 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sesn2 sestrin 2 multiple interactions ISO [Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA] CTD PMID:20530418 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sftpb surfactant protein B multiple interactions ISO
EXP
Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of SFTPB mRNA]; Ascorbic Acid inhibits the reaction [nitrofen results in decreased expression of SFTPB protein] CTD PMID:15083329, PMID:16490937, PMID:16863852 NCBI chr 4:100,166,855...100,175,941
Ensembl chr 4:100,166,863...100,175,938
JBrowse link
G Sftpc surfactant protein C decreases expression EXP Ascorbic Acid results in decreased expression of SFTPC mRNA CTD PMID:15372504 NCBI chr15:52,211,538...52,214,480
Ensembl chr15:52,211,544...52,214,616
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 decreases expression ISO Ascorbic Acid results in decreased expression of SHMT2 mRNA CTD PMID:19197388 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
G Si sucrase-isomaltase multiple interactions ISO [Quercetin co-treated with Ascorbic Acid] results in decreased expression of SI mRNA CTD PMID:17639512 NCBI chr 2:170,220,794...170,301,348
Ensembl chr 2:170,221,245...170,301,348
JBrowse link
G Slc11a2 solute carrier family 11 member 2 decreases expression
increases expression
ISO Ascorbic Acid results in decreased expression of SLC11A2 protein
Ascorbic Acid results in increased expression of SLC11A2 protein
CTD PMID:18815723 NCBI chr 7:142,025,812...142,062,892
Ensembl chr 7:142,025,815...142,063,212
JBrowse link
G Slc22a7 solute carrier family 22 member 7 increases transport ISO SLC22A7 protein results in increased transport of Ascorbic Acid CTD PMID:15901346 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
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G Slc23a1 solute carrier family 23 member 1 multiple interactions
affects uptake
increases expression
affects transport
affects abundance
decreases expression
increases transport
ISO Quercetin inhibits the reaction [SLC23A1 protein results in increased transport of Ascorbic Acid]
SLC23A1 protein affects the uptake of Ascorbic Acid
Ascorbic Acid results in increased expression of SLC23A1 mRNA
SLC23A1 protein affects the transport of Ascorbic Acid
SLC23A1 gene polymorphism affects the abundance of Ascorbic Acid
Ascorbic Acid results in decreased expression of SLC23A1 mRNA; Ascorbic Acid results in decreased expression of SLC23A1 protein
Ascorbic Acid deficiency results in increased expression of SLC23A1 mRNA; Ascorbic Acid deficiency results in increased expression of SLC23A1 protein
CTD PMID:11834736, PMID:11984597, PMID:12381735, PMID:20122894, PMID:20471816, PMID:20519558 NCBI chr18:28,413,910...28,428,133
Ensembl chr18:28,414,009...28,428,117
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G Slc23a2 solute carrier family 23 member 2 decreases expression
increases abundance
multiple interactions
increases expression
EXP
ISO
Ascorbic Acid results in decreased expression of SLC23A2 mRNA
SLC23A2 mRNA results in increased abundance of Ascorbic Acid
Ascorbic Acid inhibits the reaction [nickel sulfate results in decreased expression of SLC23A2 mRNA]; Diclofenac inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Estradiol inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Genistein inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Hydrocortisone inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Indomethacin inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Progesterone inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]; Quercetin inhibits the reaction [SLC23A2 protein results in increased uptake of Ascorbic Acid]
Ascorbic Acid deficiency results in increased expression of SLC23A2 protein; Ascorbic Acid results in increased expression of SLC23A2 mRNA
CTD PMID:16288478, PMID:17092984, PMID:19418264, PMID:20122894, PMID:22001929, PMID:22558179 NCBI chr 3:124,632,491...124,842,225
Ensembl chr 3:124,632,492...124,724,252
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G Slc2a1 solute carrier family 2 member 1 increases expression EXP Ascorbic Acid results in increased expression of SLC2A1 mRNA CTD PMID:15372504 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
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G Slc2a4 solute carrier family 2 member 4 increases expression
multiple interactions
ISO
EXP
Ascorbic Acid results in increased expression of SLC2A4 mRNA
[Ascorbic Acid co-treated with Vitamin E] inhibits the reaction [Diethylhexyl Phthalate affects the localization of SLC2A4 protein]
CTD PMID:20122894, PMID:21911000 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
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G Slc6a1 solute carrier family 6 member 1 multiple interactions EXP Ascorbic Acid inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of SLC6A1 protein] CTD PMID:31708536 NCBI chr 4:146,258,842...146,292,176
Ensembl chr 4:146,276,862...146,292,213
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G Slc7a11 solute carrier family 7 member 11 increases expression ISO Ascorbic Acid results in increased expression of SLC7A11 mRNA