Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:bevantolol
go back to main search page
Accession:CHEBI:238698 term browser browse the term
Definition:A propanolamine that is 3-aminopropane-1,2-diol in which the hydrogen of the primary hydroxy group is substituted by 3-methylphenyl and one of the hydrogens attached to the nitrogen is substituted by 2-(3,4-dimethoxyphenyl)ethyl. A beta1 adrenoceptor antagonist, it has been shown to be as effective as other beta-blockers for the treatment of angina pectoris and hypertension.
Synonyms:exact_synonym: 1-{[2-(3,4-dimethoxyphenyl)ethyl]amino}-3-(3-methylphenoxy)propan-2-ol
 related_synonym: 1-((2-(3,4-dimethoxyphenyl)ethyl)amino)-3-(3-methylphenoxy)-2-propanol;   1-(3,4-dimethoxyphenethylamino)-3-(m-tolyloxy)-2-propanol;   1-(3,4-dimethoxyphenethylamino)-3-m-tolyloxy-propan-2-ol;   1-[2-(3,4-Dimethoxy-phenyl)-ethylamino]-3-m-tolyloxy-propan-2-ol;   Formula=C20H27NO4;   InChI=1S/C20H27NO4/c1-15-5-4-6-18(11-15)25-14-17(22)13-21-10-9-16-7-8-19(23-2)20(12-16)24-3/h4-8,11-12,17,21-22H,9-10,13-14H2,1-3H3;   InChIKey=HXLAFSUPPDYFEO-UHFFFAOYSA-N;   SMILES=COc1ccc(CCNCC(O)COc2cccc(C)c2)cc1OC;   bevantololum
 xref: Beilstein:2769444;   CAS:59170-23-9;   DrugBank:DB01295;   Drug_Central:360
 xref_mesh: MESH:C021148
 xref: PMID:2871781;   PMID:2894292;   Patent:BE790165;   Patent:US3857891;   Patent:US4994618;   Reaxys:2769444


show annotations for term's descendants       view all columns           Sort by:
 
bevantolol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adrb1 adrenoceptor beta 1 JBrowse link 1 277,537,585 277,538,985 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19789
    role 19735
      application 19381
        pharmaceutical 19251
          drug 19251
            cardiovascular drug 7620
              anti-arrhythmia drug 904
                bevantolol 1
                  (R)-bevantolol 0
                  (S)-bevantolol 0
                  bevantolol hydrochloride + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19789
    subatomic particle 19787
      composite particle 19787
        hadron 19787
          baryon 19787
            nucleon 19787
              atomic nucleus 19787
                atom 19787
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19415
                        hydrogen molecular entity 19405
                          hydrides 18376
                            inorganic hydride 17224
                              pnictogen hydride 17187
                                nitrogen hydride 17021
                                  azane 16716
                                    ammonia 16715
                                      organic amino compound 16714
                                        amino alcohol 881
                                          propanolamine 170
                                            bevantolol 1
                                              (R)-bevantolol 0
                                              (S)-bevantolol 0
                                              bevantolol hydrochloride + 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.