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ONTOLOGY REPORT - ANNOTATIONS


Term:acyclovir
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Accession:CHEBI:2453 term browser browse the term
Definition:An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. Used in the treatment of viral infections.
Synonyms:exact_synonym: 2-amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one
 related_synonym: Formula=C8H11N5O3;   InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15);   InChIKey=MKUXAQIIEYXACX-UHFFFAOYSA-N;   SMILES=Nc1nc2n(COCCO)cnc2c(=O)[nH]1;   Zovir;   aciclovir;   aciclovirum;   acycloguanosine
 alt_id: CHEBI:40459
 xref: Beilstein:1219402 "Beilstein";   CAS:59277-89-3 "ChemIDplus";   CAS:59277-89-3 "KEGG COMPOUND";   DrugBank:DB00787;   Drug_Central:85 "DrugCentral";   HMDB:HMDB0014925;   KEGG:C06810;   KEGG:D00222;   LINCS:LSM-5459
 xref_mesh: MESH:D000212
 xref: PDBeChem:AC2;   PMID:11687127 "Europe PMC";   PMID:11994034 "Europe PMC";   PMID:24346595 "Europe PMC";   PMID:26024233 "Europe PMC";   PMID:28166217 "Europe PMC";   PMID:8308511 "Europe PMC";   Patent:DE2539963;   Patent:US4199574;   Reaxys:1219402 "Reaxys";   Wikipedia:Acyclovir


show annotations for term's descendants       view all columns           Sort by:
 
acyclovir term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Aqp2 aquaporin 2 JBrowse link 7 141,237,802 141,242,837 RGD:6480464
G Haao 3-hydroxyanthranilate 3,4-dioxygenase JBrowse link 6 7,045,145 7,059,227 RGD:6480464
G Ido1 indoleamine 2,3-dioxygenase 1 JBrowse link 16 72,216,326 72,228,098 RGD:6480464
G Mr1 major histocompatibility complex, class I-related JBrowse link 13 72,771,992 72,789,861 RGD:6480464
G Slc12a1 solute carrier family 12 member 1 JBrowse link 3 117,421,531 117,498,372 RGD:6480464
G Slc17a1 solute carrier family 17 member 1 JBrowse link 17 43,473,048 43,504,645 RGD:6480464
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        biochemical role 19179
          antimetabolite 8480
            acyclovir 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic molecule 19402
                              organic cyclic compound 19158
                                organic heterocyclic compound 18245
                                  organic heteropolycyclic compound 17500
                                    organic heterobicyclic compound 15910
                                      imidazopyrimidine 5415
                                        purines 5413
                                          aminopurine 4372
                                            2-aminopurines 3998
                                              guanine 3962
                                                acyclovir 8
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.