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Accession:CHEBI:258351 term browser browse the term
Definition:N-(4-Hydroxyphenyl)acetamide in which the hydrogen of the phenolic hydroxy group is substituted by a 3-(isopropylaminoamino)-2-hydroxypropyl group. A selective beta blocker, it has been used in the emergency treatment of cardiac arrhythmias.
Synonyms:exact_synonym: N-{4-[2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl}acetamide
 related_synonym: 1-(4-acetamidophenoxy)-3-isopropylamino-2-propanol;   4'-(2-hydroxy-3-(isopropylamino)propoxy)acetanilide;   Formula=C14H22N2O3;   InChI=1S/C14H22N2O3/c1-10(2)15-8-13(18)9-19-14-6-4-12(5-7-14)16-11(3)17/h4-7,10,13,15,18H,8-9H2,1-3H3,(H,16,17);   InChIKey=DURULFYMVIFBIR-UHFFFAOYSA-N;   N-(4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide;   SMILES=CC(C)NCC(O)COc1ccc(NC(C)=O)cc1;   practololum
 alt_id: CHEBI:101380;   CHEBI:8348
 xref: CAS:6673-35-4 "ChemIDplus";   CAS:6673-35-4 "KEGG COMPOUND";   DrugBank:DB01297;   Drug_Central:3486 "DrugCentral";   HMDB:HMDB0015411;   KEGG:C11696;   KEGG:D05587;   LINCS:LSM-1531
 xref_mesh: MESH:D011217
 xref: PMID:6827543 "ChEMBL";   Patent:US3408387;   Wikipedia:Practolol

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practolol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ADRB2 adrenoceptor beta 2 JBrowse link 5 148,826,611 148,828,623 RGD:6480464
G MAPK1 mitogen-activated protein kinase 1 JBrowse link 22 21,759,657 21,867,680 RGD:6480464
G MAPK3 mitogen-activated protein kinase 3 JBrowse link 16 30,114,105 30,123,309 RGD:6480464
G REN renin JBrowse link 1 204,154,819 204,166,337 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23805
    role 23692
      application 23078
        pharmaceutical 22618
          drug 22618
            cardiovascular drug 7718
              anti-arrhythmia drug 892
                practolol 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 23805
    subatomic particle 23756
      composite particle 23756
        hadron 23756
          baryon 23756
            nucleon 23756
              atomic nucleus 23756
                atom 23756
                  main group element atom 23575
                    p-block element atom 23575
                      carbon group element atom 23289
                        carbon atom 23243
                          organic molecular entity 23243
                            organic group 21924
                              organic divalent group 21896
                                organodiyl group 21896
                                  carbonyl group 21868
                                    carbonyl compound 21868
                                      carboxylic acid 20917
                                        carboacyl group 19023
                                          univalent carboacyl group 19023
                                            carbamoyl group 18370
                                              carboxamide 18370
                                                acetamides 12022
                                                  practolol 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.