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ONTOLOGY REPORT - ANNOTATIONS


Term:aminoglutethimide
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Accession:CHEBI:2654 term browser browse the term
Definition:A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Synonyms:exact_synonym: 3-(4-aminophenyl)-3-ethylpiperidine-2,6-dione
 related_synonym: 2-(p-Aminophenyl)-2-ethylglutarimide;   3-Ethyl-3-(p-aminophenyl)-2,6-dioxopiperidine;   DL-Aminoglutethimide;   Formula=C13H16N2O2;   InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17);   InChIKey=ROBVIMPUHSLWNV-UHFFFAOYSA-N;   SMILES=CCC1(CCC(=O)NC1=O)c1ccc(N)cc1;   alpha-(p-Aminophenyl)-alpha-ethylglutarimide;   aminoglutethimidum;   aminoglutetimida;   p-Aminoglutethimide
 xref: Beilstein:210656 "Beilstein";   CAS:125-84-8 "ChemIDplus";   CAS:125-84-8 "DrugBank";   CAS:125-84-8 "KEGG COMPOUND";   CAS:125-84-8 "KEGG DRUG";   CAS:125-84-8 "NIST Chemistry WebBook";   DrugBank:DB00357;   Drug_Central:164 "DrugCentral";   HMDB:HMDB0014501;   KEGG:C07617;   KEGG:D00574;   LINCS:LSM-1409
 xref_mesh: MESH:D000616
 xref: PMID:11916226 "Europe PMC";   PMID:17602675 "Europe PMC";   PMID:24350727 "Europe PMC";   Patent:US2848455;   Reaxys:210656 "Reaxys";   Wikipedia:Aminoglutethimide


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aminoglutethimide term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ACP1 acid phosphatase 1 JBrowse link 2 264,869 278,283 RGD:6480464
G ANP32B acidic nuclear phosphoprotein 32 family member B JBrowse link 9 97,983,341 98,015,943 RGD:6480464
G BASP1 brain abundant membrane attached signal protein 1 JBrowse link 5 17,216,823 17,276,845 RGD:6480464
G BCAP31 B cell receptor associated protein 31 JBrowse link X 153,700,492 153,724,746 RGD:6480464
G CCT4 chaperonin containing TCP1 subunit 4 JBrowse link 2 61,868,085 61,888,671 RGD:6480464
G CCT6A chaperonin containing TCP1 subunit 6A JBrowse link 7 56,051,765 56,063,989 RGD:6480464
G CCT7 chaperonin containing TCP1 subunit 7 JBrowse link 2 73,233,425 73,253,022 RGD:6480464
G COMT catechol-O-methyltransferase JBrowse link 22 19,941,772 19,969,975 RGD:6480464
G CUTA cutA divalent cation tolerance homolog JBrowse link 6 33,416,442 33,418,288 RGD:6480464
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 JBrowse link 15 74,337,762 74,367,646 RGD:6480464
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 JBrowse link 10 102,830,531 102,837,413 RGD:6480464
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 JBrowse link 15 51,208,057 51,338,596 RGD:6480464
G FSHB follicle stimulating hormone subunit beta JBrowse link 11 30,231,014 30,235,277 RGD:6480464
G GATD3A glutamine amidotransferase like class 1 domain containing 3A JBrowse link 21 44,133,665 44,145,711 RGD:6480464
G GNS glucosamine (N-acetyl)-6-sulfatase JBrowse link 12 64,713,449 64,759,406 RGD:6480464
G GPX1 glutathione peroxidase 1 JBrowse link 3 49,357,171 49,358,600 RGD:6480464
G GSN gelsolin JBrowse link 9 121,201,483 121,332,844 RGD:6480464
G H1-2 H1.2 linker histone, cluster member JBrowse link 6 26,055,740 26,056,471 RGD:6480464
G H2AC12 H2A clustered histone 12 JBrowse link 6 27,147,082 27,147,562 RGD:6480464
G H2AZ1 H2A.Z variant histone 1 JBrowse link 4 99,948,088 99,950,275 RGD:6480464
G H2BC12 H2B clustered histone 12 JBrowse link 6 27,138,293 27,146,858 RGD:6480464
G H3C13 H3 clustered histone 13 JBrowse link 1 149,813,225 149,813,681 RGD:6480464
G H3C7 H3 clustered histone 7 JBrowse link 6 26,250,142 26,250,607 RGD:6480464
G H4C8 H4 clustered histone 8 JBrowse link 6 26,285,126 26,285,499 RGD:6480464
G HMGB2 high mobility group box 2 JBrowse link 4 173,331,376 173,334,358 RGD:6480464
G HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 JBrowse link 5 179,614,178 179,634,784 RGD:6480464
G HSD17B1 hydroxysteroid 17-beta dehydrogenase 1 JBrowse link 17 42,552,923 42,555,214 RGD:6480464
G HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 JBrowse link X 53,431,258 53,434,376 RGD:6480464
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 JBrowse link 5 119,452,497 119,542,332 RGD:6480464
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 JBrowse link 1 162,790,702 162,812,818 RGD:6480464
G HSPA1A heat shock protein family A (Hsp70) member 1A JBrowse link 6 31,815,543 31,817,942 RGD:6480464
G HYOU1 hypoxia up-regulated 1 JBrowse link 11 119,044,187 119,057,205 RGD:6480464
G IMPDH2 inosine monophosphate dehydrogenase 2 JBrowse link 3 49,024,325 49,029,750 RGD:6480464
G LHB luteinizing hormone subunit beta JBrowse link 19 49,015,980 49,017,090 RGD:6480464
G LMNA lamin A/C JBrowse link 1 156,082,546 156,140,089 RGD:6480464
G LMNB2 lamin B2 JBrowse link 19 2,428,166 2,456,959 RGD:6480464
G MCM3 minichromosome maintenance complex component 3 JBrowse link 6 52,264,015 52,284,742 RGD:6480464
G MPO myeloperoxidase JBrowse link 17 58,269,855 58,280,935 RGD:6480464
G MYO18A myosin XVIIIA JBrowse link 17 29,071,122 29,180,398 RGD:6480464
G NPM3 nucleophosmin/nucleoplasmin 3 JBrowse link 10 101,781,325 101,783,413 RGD:6480464
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 3 119,780,484 119,818,485 RGD:6480464
G NUP210 nucleoporin 210 JBrowse link 3 13,316,235 13,420,322 RGD:6480464
G PGR progesterone receptor JBrowse link 11 101,029,624 101,130,681 RGD:6480464
G PITPNB phosphatidylinositol transfer protein beta JBrowse link 22 27,851,669 27,919,306 RGD:6480464
G PPP1CA protein phosphatase 1 catalytic subunit alpha JBrowse link 11 67,398,183 67,401,858 RGD:6480464
G PRDX3 peroxiredoxin 3 JBrowse link 10 119,167,720 119,178,812 RGD:6480464
G PSMB4 proteasome 20S subunit beta 4 JBrowse link 1 151,399,573 151,401,937 RGD:6480464
G RTRAF RNA transcription, translation and transport factor JBrowse link 14 51,989,546 52,010,694 RGD:6480464
G SPP1 secreted phosphoprotein 1 JBrowse link 4 87,975,650 87,983,411 RGD:6480464
G SSB small RNA binding exonuclease protection factor La JBrowse link 2 169,798,871 169,812,064 RGD:6480464
G STAR steroidogenic acute regulatory protein JBrowse link 8 38,142,700 38,150,952 RGD:6480464
G TPT1 tumor protein, translationally-controlled 1 JBrowse link 13 45,333,471 45,341,284 RGD:6480464
G UBC ubiquitin C JBrowse link 12 124,911,646 124,914,650 RGD:6480464
G UBE2K ubiquitin conjugating enzyme E2 K JBrowse link 4 39,698,136 39,782,792 RGD:6480464
G WDR1 WD repeat domain 1 JBrowse link 4 10,074,339 10,116,860 RGD:6480464
G YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta JBrowse link 2 9,583,967 9,630,997 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 23673
    role 23561
      application 22941
        pharmaceutical 22479
          drug 22479
            antineoplastic agent 18520
              aminoglutethimide 56
                (R)-aminoglutethimide 0
                (S)-aminoglutethimide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 23673
    subatomic particle 23620
      composite particle 23620
        hadron 23620
          baryon 23620
            nucleon 23620
              atomic nucleus 23620
                atom 23620
                  main group element atom 23437
                    main group molecular entity 23437
                      s-block molecular entity 22611
                        hydrogen molecular entity 22393
                          hydrides 20497
                            inorganic hydride 18711
                              pnictogen hydride 18669
                                nitrogen hydride 18359
                                  azane 18211
                                    ammonia 18208
                                      organic amino compound 18207
                                        aromatic amine 14314
                                          anilines 13019
                                            substituted aniline 12436
                                              aminoglutethimide 56
                                                (R)-aminoglutethimide 0
                                                (S)-aminoglutethimide 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.