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ONTOLOGY REPORT - ANNOTATIONS


Term:amodiaquine
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Accession:CHEBI:2674 term browser browse the term
Definition:A quinoline having a chloro group at the 7-position and an aryl amino group at the 4-position.
Synonyms:exact_synonym: 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol
 related_synonym: Formula=C20H22ClN3O;   InChI=1S/C20H22ClN3O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);   InChIKey=OVCDSSHSILBFBN-UHFFFAOYSA-N;   SMILES=CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O;   amodiaquina;   amodiaquinum
 xref: Beilstein:300962 "Beilstein";   CAS:86-42-0 "ChemIDplus";   DrugBank:DB00613;   Drug_Central:186 "DrugCentral";   KEGG:C07626;   KEGG:D02922;   LINCS:LSM-4042
 xref_mesh: MESH:D000655
 xref: PDBeChem:CQA;   PMID:11044276 "Europe PMC";   PMID:11971651 "Europe PMC";   PMID:17046445 "Europe PMC";   PMID:17222819 "Europe PMC";   PMID:18419816 "Europe PMC";   PMID:18855526 "Europe PMC";   PMID:19024339 "Europe PMC";   PMID:19245687 "Europe PMC";   PMID:26206402 "Europe PMC";   PMID:26597254 "Europe PMC";   PMID:26647924 "Europe PMC";   PMID:26735991 "Europe PMC";   PMID:26851641 "Europe PMC";   PMID:26900802 "Europe PMC";   PMID:26930583 "Europe PMC";   PMID:27031231 "Europe PMC";   PMID:8885219 "Europe PMC";   Patent:US2474821;   Reaxys:300962 "Reaxys";   Wikipedia:Amodiaquine
 cyclic_relationship: is_conjugate_base_of CHEBI:131327


show annotations for term's descendants       view all columns           Sort by:
 
amodiaquine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ache acetylcholinesterase JBrowse link 12 22,472,358 22,477,052 RGD:6480464
G Bche butyrylcholinesterase JBrowse link 2 171,104,476 171,196,186 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 JBrowse link 9 67,699,397 67,706,068 RGD:6480464
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:6480464
G Ctsd cathepsin D JBrowse link 1 215,541,570 215,553,446 RGD:6480464
G Ctsl cathepsin L JBrowse link 17 1,873,105 1,879,266 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 JBrowse link 7 123,599,264 123,608,436 RGD:6480464
G E2f1 E2F transcription factor 1 JBrowse link 3 150,062,895 150,073,721 RGD:6480464
G Gpt glutamic--pyruvic transaminase JBrowse link 7 117,759,083 117,761,932 RGD:6480464
G Lag3 lymphocyte activating 3 JBrowse link 4 157,425,644 157,433,700 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 JBrowse link 17 32,131,847 32,158,559 RGD:6480464
G Pdcd1 programmed cell death 1 JBrowse link 9 101,305,742 101,319,937 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        pro-agent 8766
          prodrug 8563
            amodiaquine 22
              amodiaquine hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    main group molecular entity 19531
                      s-block molecular entity 19314
                        hydrogen molecular entity 19303
                          hydrides 18231
                            inorganic hydride 17095
                              pnictogen hydride 17053
                                nitrogen hydride 16874
                                  azane 16551
                                    ammonia 16548
                                      organic amino compound 16547
                                        aromatic amine 13576
                                          aminoquinoline 1557
                                            amodiaquine 22
                                              amodiaquine hydrochloride 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.