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ONTOLOGY REPORT - ANNOTATIONS


Term:amoxapine
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Accession:CHEBI:2675 term browser browse the term
Definition:A dibenzooxazepine compound having a chloro substituent at the 2-position and a piperazin-1-yl group at the 11-position.
Synonyms:exact_synonym: 2-chloro-11-(piperazin-1-yl)dibenzo[b,f][1,4]oxazepine
 related_synonym: 2-Chloro-11-(1-piperazinyl)dibenz(b,f)(1,4)oxazepine;   Desmethylloxapin;   Formula=C17H16ClN3O;   InChI=1S/C17H16ClN3O/c18-12-5-6-15-13(11-12)17(21-9-7-19-8-10-21)20-14-3-1-2-4-16(14)22-15/h1-6,11,19H,7-10H2;   InChIKey=QWGDMFLQWFTERH-UHFFFAOYSA-N;   SMILES=Clc1ccc2Oc3ccccc3N=C(N3CCNCC3)c2c1;   amoxapina;   amoxapinum
 xref: Beilstein:832057;   CAS:14028-44-5;   DrugBank:DB00543;   Drug_Central:191;   KEGG:D00228;   LINCS:LSM-2021
 xref_mesh: MESH:D000657
 xref: Patent:FR1508536;   Patent:US3663696;   Wikipedia:Amoxapine


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amoxapine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Drd1 dopamine receptor D1 JBrowse link 17 11,099,736 11,104,352 RGD:6480464
G Drd2 dopamine receptor D2 JBrowse link 8 53,678,777 53,743,643 RGD:6480464
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 JBrowse link 3 41,019,898 41,181,070 RGD:6480464
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 JBrowse link 8 33,435,493 33,463,410 RGD:6480464
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 JBrowse link 11 35,011,007 35,262,362 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19789
    role 19735
      biological role 19734
        pharmacological role 18817
          neurotransmitter agent 16446
            adrenergic agent 8925
              adrenergic uptake inhibitor 4668
                amoxapine 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19789
    subatomic particle 19787
      composite particle 19787
        hadron 19787
          baryon 19787
            nucleon 19787
              atomic nucleus 19787
                atom 19787
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19569
                        carbon atom 19558
                          organic molecular entity 19558
                            organic molecule 19480
                              organic cyclic compound 19239
                                organic heterocyclic compound 18352
                                  organic heteropolycyclic compound 17703
                                    organic heterotricyclic compound 14579
                                      dibenzooxazepine 21
                                        amoxapine 7
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.