Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:anastrozole
go back to main search page
Accession:CHEBI:2704 term browser browse the term
Definition:A 1,2,4-triazole compound having a 3,5-bis(2-cyano-2-propyl)benzyl group at the 1-position.
Synonyms:exact_synonym: 2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
 related_synonym: Anastrozol;   Formula=C17H19N5;   InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3;   InChIKey=YBBLVLTVTVSKRW-UHFFFAOYSA-N;   SMILES=CC(C)(C#N)c1cc(Cn2cncn2)cc(c1)C(C)(C)C#N;   alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
 xref: Beilstein:8005958 "Beilstein";   CAS:120511-73-1 "ChemIDplus";   CAS:120511-73-1 "DrugBank";   CAS:120511-73-1 "KEGG COMPOUND";   CAS:120511-73-1 "KEGG DRUG";   DrugBank:DB01217;   Drug_Central:210 "DrugCentral";   KEGG:C08159;   KEGG:D00960;   LINCS:LSM-5631
 xref_mesh: MESH:C090450
 xref: Patent:EP296749;   Patent:US4935437;   Wikipedia:Anastrozole


show annotations for term's descendants       view all columns           Sort by:
 
anastrozole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Gja1 gap junction protein, alpha 1 JBrowse link 20 37,876,650 37,889,097 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Mki67 marker of proliferation Ki-67 JBrowse link 1 207,993,895 208,020,454 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    chemical entity 19652
      group 19568
        pseudohalo group 2769
          cyano group 2769
            nitrile 2769
              anastrozole 8
                1-\{[3,5-bis(1-cyano-1-methylethyl)phenyl]methyl\}-4-[(3S,4R,5R,6R)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]-1,2,4lambda5-triazol-4-ylium 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                organic heterocyclic compound 18151
                                  heteroarene 15151
                                    monocyclic heteroarene 11614
                                      azole 10473
                                        triazoles 3604
                                          anastrozole 8
                                            1-\{[3,5-bis(1-cyano-1-methylethyl)phenyl]methyl\}-4-[(3S,4R,5R,6R)-6-carboxy-3,4,5-trihydroxyoxan-2-yl]-1,2,4lambda5-triazol-4-ylium 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.