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ONTOLOGY REPORT - ANNOTATIONS


Term:actinomycin D
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Accession:CHEBI:27666 term browser browse the term
Definition:An actinomycin that has formula C62H86N12O16.
Synonyms:exact_synonym: 2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis-[(18aS)-10c,14,17-trimethyl-5,8,12,15,18-pentaoxo-6c,13t-di(propan-2-yl)-18ar-hexadecahydro-1H-pyrrolo[2,1-i][1,4,7,10,13]oxatetraazacyclohexadecin-9c-yl]-3H-phenoxazine-1,9-dicarboxamide
 related_synonym: 2-amino-N,N'-bis(hexadecahydro-2,5,9-trimethyl-6,13-bis(1-methylethyl)-1,4,7,11,14-pentaoxo-1H-pyrrolo(2,1-i)(1,4,7,10,13)oxatetra-azacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide;   ActD;   Dactinomycin;   Formula=C62H86N12O16;   InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1;   InChIKey=RJURFGZVJUQBHK-IIXSONLDSA-N;   SMILES=[H][C@@]12CCCN1C(=O)[C@H](NC(=O)[C@@H](NC(=O)c1ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@]6([H])CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc13)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C2=O)C(C)C;   actinomycin C1;   actinomycin IV
 alt_id: CHEBI:22218;   CHEBI:2446
 xref: Beilstein:4173766 "Beilstein";   CAS:50-76-0 "ChemIDplus";   CAS:50-76-0 "KEGG COMPOUND";   DrugBank:DB00970;   Drug_Central:774 "DrugCentral";   KEGG:C06770;   KEGG:D00214;   LINCS:LSM-5783
 xref_mesh: MESH:D003609
 xref: Wikipedia:Dactinomycin


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actinomycin D term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A JBrowse link 5 8,567,091 8,748,575 RGD:6480464
G Abcb1b ATP-binding cassette, sub-family B (MDR/TAP), member 1B JBrowse link 5 8,798,147 8,866,314 RGD:6480464
G Abcc1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 JBrowse link 16 14,361,453 14,474,878 RGD:6480464
G Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 JBrowse link 19 43,782,308 43,838,332 RGD:6480464
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) JBrowse link 6 58,584,491 58,692,451 RGD:6480464
G Abhd3 abhydrolase domain containing 3 JBrowse link 18 10,644,411 10,706,783 RGD:6480464
G Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 JBrowse link 11 105,967,948 105,989,964 RGD:6480464
G Acsl6 acyl-CoA synthetase long-chain family member 6 JBrowse link 11 54,303,805 54,364,756 RGD:6480464
G Adam9 a disintegrin and metallopeptidase domain 9 (meltrin gamma) JBrowse link 8 24,949,611 25,017,040 RGD:6480464
G Adrb2 adrenergic receptor, beta 2 JBrowse link 18 62,177,713 62,179,981 RGD:6480464
G Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) JBrowse link 8 124,556,587 124,569,706 RGD:6480464
G Ahr aryl-hydrocarbon receptor JBrowse link 12 35,497,979 35,534,989 RGD:6480464
G Aicda activation-induced cytidine deaminase JBrowse link 6 122,553,809 122,564,180 RGD:6480464
G Aifm1 apoptosis-inducing factor, mitochondrion-associated 1 JBrowse link X 48,474,944 48,513,563 RGD:6480464
G Akt1 thymoma viral proto-oncogene 1 JBrowse link 12 112,653,821 112,674,884 RGD:6480464
G Alpi alkaline phosphatase, intestinal JBrowse link 1 87,098,002 87,101,606 RGD:6480464
G Aoc1 amine oxidase, copper-containing 1 JBrowse link 6 48,895,255 48,909,188 RGD:6480464
G Aqp1 aquaporin 1 JBrowse link 6 55,336,299 55,348,555 RGD:6480464
G Arhgdib Rho, GDP dissociation inhibitor (GDI) beta JBrowse link 6 136,923,655 136,941,943 RGD:6480464
G Arnt aryl hydrocarbon receptor nuclear translocator JBrowse link 3 95,434,367 95,497,240 RGD:6480464
G Atf4 activating transcription factor 4 JBrowse link 15 80,255,184 80,257,545 RGD:6480464
G Atg7 autophagy related 7 JBrowse link 6 114,643,097 114,860,614 RGD:6480464
G Atm ataxia telangiectasia mutated JBrowse link 9 53,437,122 53,536,828 RGD:6480464
G Avp arginine vasopressin JBrowse link 2 130,580,620 130,582,588 RGD:6480464
G Axl AXL receptor tyrosine kinase JBrowse link 7 25,756,500 25,788,924 RGD:6480464
G Bag3 BCL2-associated athanogene 3 JBrowse link 7 128,523,583 128,546,981 RGD:6480464
G Bak1 BCL2-antagonist/killer 1 JBrowse link 17 27,019,812 27,028,627 RGD:6480464
G Bax BCL2-associated X protein JBrowse link 7 45,461,695 45,466,903 RGD:6480464
G Bbc3 BCL2 binding component 3 JBrowse link 7 16,308,398 16,318,334 RGD:6480464
G Bcl2 B cell leukemia/lymphoma 2 JBrowse link 1 106,538,176 106,714,290 RGD:6480464
G Bcl2a1b B cell leukemia/lymphoma 2 related protein A1b JBrowse link 9 89,199,273 89,207,838 RGD:6480464
G Bcl2l1 BCL2-like 1 JBrowse link 2 152,758,732 152,833,803 RGD:6480464
G Bcl2l11 BCL2-like 11 (apoptosis facilitator) JBrowse link 2 128,126,038 128,162,547 RGD:6480464
G Bdnf brain derived neurotrophic factor JBrowse link 2 109,674,700 109,727,043 RGD:6480464
G Becn1 beclin 1, autophagy related JBrowse link 11 101,288,258 101,302,286 RGD:6480464
G Bid BH3 interacting domain death agonist JBrowse link 6 120,893,119 120,917,062 RGD:6480464
G Birc3 baculoviral IAP repeat-containing 3 JBrowse link 9 7,847,468 7,873,205 RGD:6480464
G Bnip3 BCL2/adenovirus E1B interacting protein 3 JBrowse link 7 138,890,836 138,909,506 RGD:6480464
G Bsdc1 BSD domain containing 1 JBrowse link 4 129,461,679 129,488,498 RGD:6480464
G C1qbp complement component 1, q subcomponent binding protein JBrowse link 11 70,977,846 70,983,026 RGD:6480464
G Cacna1g calcium channel, voltage-dependent, T type, alpha 1G subunit JBrowse link 11 94,408,391 94,474,400 RGD:6480464
G Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit JBrowse link 17 25,374,285 25,436,334 RGD:6480464
G Casp2 caspase 2 JBrowse link 6 42,264,902 42,282,508 RGD:6480464
G Casp3 caspase 3 JBrowse link 8 46,617,291 46,639,698 RGD:6480464
G Casp7 caspase 7 JBrowse link 19 56,396,833 56,442,348 RGD:6480464
G Casp8 caspase 8 JBrowse link 1 58,795,233 58,847,503 RGD:6480464
G Casp9 caspase 9 JBrowse link 4 141,793,612 141,815,978 RGD:6480464
G Cav1 caveolin 1, caveolae protein JBrowse link 6 17,306,335 17,341,328 RGD:6480464
G Ccl11 chemokine (C-C motif) ligand 11 JBrowse link 11 82,057,832 82,062,955 RGD:6480464
G Ccl2 chemokine (C-C motif) ligand 2 JBrowse link 11 82,035,577 82,037,452 RGD:6480464
G Ccn4 cellular communication network factor 4 JBrowse link 15 66,891,369 66,923,201 RGD:6480464
G Ccna2 cyclin A2 JBrowse link 3 36,564,865 36,573,038 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 7 144,929,931 144,939,937 RGD:6480464
G Cd1d1 CD1d1 antigen JBrowse link 3 86,995,834 87,012,358 RGD:6480464
G Cd28 CD28 antigen JBrowse link 1 60,746,388 60,773,359 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) JBrowse link 17 29,090,979 29,100,722 RGD:6480464
G Cebpb CCAAT/enhancer binding protein (C/EBP), beta JBrowse link 2 167,688,915 167,690,432 RGD:6480464
G Cel carboxyl ester lipase JBrowse link 2 28,555,819 28,563,403 RGD:6480464
G Cflar CASP8 and FADD-like apoptosis regulator JBrowse link 1 58,711,311 58,758,884 RGD:6480464
G Ckb creatine kinase, brain JBrowse link 12 111,669,355 111,672,338 RGD:6480464
G Clmn calmin JBrowse link 12 104,763,114 104,865,082 RGD:6480464
G Cnmd chondromodulin JBrowse link 14 79,637,682 79,662,194 RGD:6480464
G Cnr1 cannabinoid receptor 1 (brain) JBrowse link 4 33,923,171 33,948,831 RGD:6480464
G Cnr2 cannabinoid receptor 2 (macrophage) JBrowse link 4 135,895,189 135,920,219 RGD:6480464
G Col1a1 collagen, type I, alpha 1 JBrowse link 11 94,936,224 94,953,042 RGD:6480464
G Col1a2 collagen, type I, alpha 2 JBrowse link 6 4,505,618 4,541,543 RGD:6480464
G Crabp2 cellular retinoic acid binding protein II JBrowse link 3 87,948,693 87,953,372 RGD:6480464
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) JBrowse link 11 54,247,270 54,249,899 RGD:6480464
G Ctf1 cardiotrophin 1 JBrowse link 7 127,712,676 127,718,188 RGD:6480464
G Cxcl15 chemokine (C-X-C motif) ligand 15 JBrowse link 5 90,794,534 90,803,067 RGD:6480464
G Cycs cytochrome c, somatic JBrowse link 6 50,562,563 50,566,569 RGD:6480464
G Cygb cytoglobin JBrowse link 11 116,645,595 116,654,504 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 9 57,687,928 57,703,824 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 9 57,676,937 57,683,655 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 17 79,706,940 79,715,061 RGD:6480464
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 JBrowse link 7 26,835,339 26,843,264 RGD:6480464
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 JBrowse link 7 25,897,658 25,926,624 RGD:6480464
G Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 JBrowse link 7 27,119,955 27,133,660 RGD:6480464
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 JBrowse link 7 25,802,469 25,816,525 RGD:6480464
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 JBrowse link 5 145,854,607 145,879,854 RGD:6480464
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 JBrowse link 5 137,892,933 137,925,610 RGD:6480464
G Ddah2 dimethylarginine dimethylaminohydrolase 2 JBrowse link 17 35,059,035 35,062,099 RGD:6480464
G Dio3 deiodinase, iodothyronine type III JBrowse link 12 110,279,230 110,281,097 RGD:6480464
G Dpysl4 dihydropyrimidinase-like 4 JBrowse link 7 139,085,981 139,101,795 RGD:6480464
G Edn1 endothelin 1 JBrowse link 13 42,301,476 42,307,990 RGD:6480464
G Ednra endothelin receptor type A JBrowse link 8 77,663,029 77,724,452 RGD:6480464
G Ednrb endothelin receptor type B JBrowse link 14 103,814,615 103,844,508 RGD:6480464
G Efnb2 ephrin B2 JBrowse link 8 8,617,235 8,661,242 RGD:6480464
G Egf epidermal growth factor JBrowse link 3 129,677,574 129,755,322 RGD:6480464
G Egfr epidermal growth factor receptor JBrowse link 11 16,752,203 16,913,907 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 34,861,207 34,864,956 RGD:6480464
G Elovl3 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 JBrowse link 19 46,131,862 46,135,694 RGD:6480464
G Emp1 epithelial membrane protein 1 JBrowse link 6 135,362,550 135,383,173 RGD:6480464
G Emp3 epithelial membrane protein 3 JBrowse link 7 45,918,023 45,921,426 RGD:6480464
G Epas1 endothelial PAS domain protein 1 JBrowse link 17 86,753,864 86,833,410 RGD:6480464
G F3 coagulation factor III JBrowse link 3 121,723,537 121,735,052 RGD:6480464
G Fadd Fas (TNFRSF6)-associated via death domain JBrowse link 7 144,578,323 144,582,441 RGD:6480464
G Fads3 fatty acid desaturase 3 JBrowse link 19 10,040,855 10,060,113 RGD:6480464
G Fbl fibrillarin JBrowse link 7 28,168,893 28,179,269 RGD:6480464
G Fgf2 fibroblast growth factor 2 JBrowse link 3 37,348,477 37,410,106 RGD:6480464
G Fgfr1 fibroblast growth factor receptor 1 JBrowse link 8 25,518,759 25,575,718 RGD:6480464
G Fhl1 four and a half LIM domains 1 JBrowse link X 56,731,209 56,793,346 RGD:6480464
G Flnc filamin C, gamma JBrowse link 6 29,433,153 29,461,889 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 1 71,585,473 71,653,280 RGD:6480464
G Fos FBJ osteosarcoma oncogene JBrowse link 12 85,473,890 85,477,274 RGD:6480464
G Fosl1 fos-like antigen 1 JBrowse link 19 5,447,698 5,455,938 RGD:6480464
G G6pdx glucose-6-phosphate dehydrogenase X-linked JBrowse link X 74,409,483 74,428,880 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha JBrowse link 6 67,035,096 67,037,407 RGD:6480464
G Galm galactose mutarotase JBrowse link 17 80,127,458 80,185,032 RGD:6480464
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link 6 125,161,852 125,166,467 RGD:6480464
G Gas6 growth arrest specific 6 JBrowse link 8 13,465,374 13,494,535 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 9 77,754,535 77,794,489 RGD:6480464
G Gdf15 growth differentiation factor 15 JBrowse link 8 70,629,393 70,632,470 RGD:6480464
G Gdnf glial cell line derived neurotrophic factor JBrowse link 15 7,810,048 7,837,580 RGD:6480464
G Gfer growth factor, augmenter of liver regeneration JBrowse link 17 24,693,189 24,697,159 RGD:6480464
G Gpr137b G protein-coupled receptor 137B JBrowse link 13 13,357,620 13,393,644 RGD:6480464
G Gpt glutamic pyruvic transaminase, soluble JBrowse link 15 76,696,726 76,699,675 RGD:6480464
G Grm5 glutamate receptor, metabotropic 5 JBrowse link 7 87,583,981 88,135,063 RGD:6480464
G Gsta1 glutathione S-transferase, alpha 1 (Ya) JBrowse link 9 78,230,669 78,242,683 RGD:6480464
G Gstp1 glutathione S-transferase, pi 1 JBrowse link 19 4,035,411 4,037,912 RGD:6480464
G H2ax H2A.X variant histone JBrowse link 9 44,334,715 44,336,077 RGD:6480464
G Hbegf heparin-binding EGF-like growth factor JBrowse link 18 36,504,927 36,515,805 RGD:6480464
G Hgf hepatocyte growth factor JBrowse link 5 16,553,495 16,619,439 RGD:6480464
G Hif1a hypoxia inducible factor 1, alpha subunit JBrowse link 12 73,901,324 73,947,554 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 8 75,093,618 75,100,593 RGD:6480464
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 JBrowse link 15 103,239,943 103,246,698 RGD:6480464
G Homer3 homer scaffolding protein 3 JBrowse link 8 70,282,880 70,294,361 RGD:6480464
G Hras Harvey rat sarcoma virus oncogene JBrowse link 7 141,189,934 141,194,019 RGD:6480464
G Hsf1 heat shock factor 1 JBrowse link 15 76,477,362 76,501,155 RGD:6480464
G Hspa5 heat shock protein 5 JBrowse link 2 34,772,090 34,776,529 RGD:6480464
G Htr3a 5-hydroxytryptamine (serotonin) receptor 3A JBrowse link 9 48,899,213 48,911,152 RGD:6480464
G Id1 inhibitor of DNA binding 1, HLH protein JBrowse link 2 152,736,251 152,737,410 RGD:6480464
G Ier3 immediate early response 3 JBrowse link 17 35,821,713 35,822,911 RGD:6480464
G Ier5 immediate early response 5 JBrowse link 1 155,096,367 155,099,636 RGD:6480464
G Ifnb1 interferon beta 1, fibroblast JBrowse link 4 88,522,025 88,522,794 RGD:6480464
G Ifng interferon gamma JBrowse link 10 118,441,046 118,445,894 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 10 87,858,265 87,937,047 RGD:6480464
G Il10 interleukin 10 JBrowse link 1 131,019,845 131,024,970 RGD:6480464
G Il11 interleukin 11 JBrowse link 7 4,772,373 4,782,907 RGD:6480464
G Il17a interleukin 17A JBrowse link 1 20,730,905 20,734,496 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 2 129,299,609 129,310,186 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 2 129,364,569 129,371,164 RGD:6480464
G Il2 interleukin 2 JBrowse link 3 37,120,713 37,125,954 RGD:6480464
G Il27ra interleukin 27 receptor, alpha JBrowse link 8 84,030,286 84,042,600 RGD:6480464
G Il6 interleukin 6 JBrowse link 5 30,013,114 30,019,975 RGD:6480464
G Ins2 insulin II JBrowse link 7 142,678,656 142,679,726 RGD:6480464
G Irf1 interferon regulatory factor 1 JBrowse link 11 53,769,854 53,778,374 RGD:6480464
G Itga2b integrin alpha 2b JBrowse link 11 102,453,297 102,469,883 RGD:6480464
G Itpr1 inositol 1,4,5-trisphosphate receptor 1 JBrowse link 6 108,213,083 108,551,116 RGD:6480464
G Jak2 Janus kinase 2 JBrowse link 19 29,251,803 29,313,095 RGD:6480464
G Jun jun proto-oncogene JBrowse link 4 95,049,036 95,052,222 RGD:6480464
G Kif1a kinesin family member 1A JBrowse link 1 93,015,455 93,102,039 RGD:6480464
G Kras Kirsten rat sarcoma viral oncogene homolog JBrowse link 6 145,216,699 145,250,420 RGD:6480464
G Krt80 keratin 80 JBrowse link 15 101,348,315 101,370,162 RGD:6480464
G Lamc2 laminin, gamma 2 JBrowse link 1 153,122,756 153,186,447 RGD:6480464
G Lep leptin JBrowse link 6 29,060,221 29,073,876 RGD:6480464
G Lgals3 lectin, galactose binding, soluble 3 JBrowse link 14 47,373,860 47,386,167 RGD:6480464
G Lgals7 lectin, galactose binding, soluble 7 JBrowse link 7 28,863,796 28,866,285 RGD:6480464
G Lmnb1 lamin B1 JBrowse link 18 56,707,813 56,753,424 RGD:6480464
G Map1lc3b microtubule-associated protein 1 light chain 3 beta JBrowse link 8 121,590,438 121,598,760 RGD:6480464
G Map2k4 mitogen-activated protein kinase kinase 4 JBrowse link 11 65,688,244 65,788,359 RGD:6480464
G Map3k7 mitogen-activated protein kinase kinase kinase 7 JBrowse link 4 31,963,492 32,023,470 RGD:6480464
G Mapk1 mitogen-activated protein kinase 1 JBrowse link 16 16,983,382 17,047,453 RGD:6480464
G Mapk3 mitogen-activated protein kinase 3 JBrowse link 7 126,759,626 126,765,816 RGD:6480464
G Mcl1 myeloid cell leukemia sequence 1 JBrowse link 3 95,656,944 95,663,179 RGD:6480464
G Mir21a microRNA 21a JBrowse link 11 86,584,067 86,584,158 RGD:6480464
G Mir22 microRNA 22 JBrowse link 11 75,463,716 75,463,810 RGD:6480464
G Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 JBrowse link 3 95,218,544 95,229,632 RGD:6480464
G Mmp1a matrix metallopeptidase 1a (interstitial collagenase) JBrowse link 9 7,464,141 7,476,869 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 2 164,940,326 164,955,850 RGD:6480464
G Mn1 meningioma 1 JBrowse link 5 111,417,300 111,457,030 RGD:6480464
G Mrpl41 mitochondrial ribosomal protein L41 JBrowse link 2 24,972,470 24,975,098 RGD:6480464
G Mt1 metallothionein 1 JBrowse link 8 94,178,883 94,180,327 RGD:6480464
G Mt2 metallothionein 2 JBrowse link 8 94,172,618 94,173,567 RGD:6480464
G Mttp microsomal triglyceride transfer protein JBrowse link 3 138,089,855 138,143,418 RGD:6480464
G Myc myelocytomatosis oncogene JBrowse link 15 61,985,341 61,990,361 RGD:6480464
G Mylk myosin, light polypeptide kinase JBrowse link 16 34,745,199 35,002,436 RGD:6480464
G Nav2 neuron navigator 2 JBrowse link 7 48,959,063 49,610,090 RGD:6480464
G Ncf1 neutrophil cytosolic factor 1 JBrowse link 5 134,220,053 134,229,628 RGD:6480464
G Ndrg1 N-myc downstream regulated gene 1 JBrowse link 15 66,929,318 66,969,641 RGD:6480464
G Nedd9 neural precursor cell expressed, developmentally down-regulated gene 9 JBrowse link 13 41,309,916 41,487,362 RGD:6480464
G Neto2 neuropilin (NRP) and tolloid (TLL)-like 2 JBrowse link 8 85,636,718 85,700,952 RGD:6480464
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 JBrowse link 2 75,675,513 75,704,663 RGD:6480464
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 JBrowse link 3 135,584,655 135,691,969 RGD:6480464
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha JBrowse link 12 55,489,409 55,492,647 RGD:6480464
G Ngf nerve growth factor JBrowse link 3 102,469,919 102,521,013 RGD:6480464
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 11 59,541,569 59,566,955 RGD:6480464
G Nos2 nitric oxide synthase 2, inducible JBrowse link 11 78,920,787 78,960,226 RGD:6480464
G Nppc natriuretic peptide type C JBrowse link 1 86,666,293 86,670,573 RGD:6480464
G Nqo1 NAD(P)H dehydrogenase, quinone 1 JBrowse link 8 107,388,225 107,403,205 RGD:6480464
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 JBrowse link X 86,191,775 86,195,947 RGD:6480464
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 JBrowse link 4 133,553,376 133,556,686 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 10 89,454,234 89,533,645 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 16 38,248,349 38,294,849 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 39,410,545 39,519,421 RGD:6480464
G Nthl1 nth (endonuclease III)-like 1 (E.coli) JBrowse link 17 24,632,680 24,638,838 RGD:6480464
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 16 29,579,281 29,663,127 RGD:6480464
G Pappa pregnancy-associated plasma protein A JBrowse link 4 65,124,174 65,357,509 RGD:6480464
G Parp1 poly (ADP-ribose) polymerase family, member 1 JBrowse link 1 180,568,891 180,600,999 RGD:6480464
G Pcna proliferating cell nuclear antigen JBrowse link 2 132,249,286 132,253,180 RGD:6480464
G Plat plasminogen activator, tissue JBrowse link 8 22,757,722 22,782,848 RGD:6480464
G Plau plasminogen activator, urokinase JBrowse link 14 20,836,662 20,843,388 RGD:6480464
G Pld1 phospholipase D1 JBrowse link 3 27,938,459 28,133,362 RGD:6480464
G Pld2 phospholipase D2 JBrowse link 11 70,539,492 70,558,110 RGD:6480464
G Polh polymerase (DNA directed), eta (RAD 30 related) JBrowse link 17 46,171,355 46,202,641 RGD:6480464
G Polr2a polymerase (RNA) II (DNA directed) polypeptide A JBrowse link 11 69,733,997 69,758,633 RGD:6480464
G Pomt1 protein-O-mannosyltransferase 1 JBrowse link 2 32,236,590 32,255,005 RGD:6480464
G Prdx1 peroxiredoxin 1 JBrowse link 4 116,685,599 116,700,000 RGD:6480464
G Prdx6 peroxiredoxin 6 JBrowse link 1 161,240,112 161,251,210 RGD:6480464
G Prkcd protein kinase C, delta JBrowse link 14 30,595,353 30,626,414 RGD:6480464
G Prl prolactin JBrowse link 13 27,057,570 27,065,204 RGD:6480464
G Procr protein C receptor, endothelial JBrowse link 2 155,751,125 155,755,478 RGD:6480464
G Prom1 prominin 1 JBrowse link 5 43,993,621 44,102,047 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 1 150,100,031 150,108,234 RGD:6480464
G Ptk2 PTK2 protein tyrosine kinase 2 JBrowse link 15 73,205,102 73,423,820 RGD:6480464
G Rad51 RAD51 recombinase JBrowse link 2 119,112,814 119,136,073 RGD:6480464
G Raf1 v-raf-leukemia viral oncogene 1 JBrowse link 6 115,618,569 115,676,635 RGD:6480464
G Rel reticuloendotheliosis oncogene JBrowse link 11 23,736,847 23,770,969 RGD:6480464
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) JBrowse link 19 5,637,442 5,648,134 RGD:6480464
G Ren1 renin 1 structural JBrowse link 1 133,350,674 133,360,320 RGD:6480464
G Retsat retinol saturase (all trans retinol 13,14 reductase) JBrowse link 6 72,598,602 72,607,488 RGD:6480464
G Rhob ras homolog family member B JBrowse link 12 8,497,661 8,500,009 RGD:6480464
G Ripply3 ripply transcriptional repressor 3 JBrowse link 16 94,328,422 94,336,935 RGD:6480464
G Rnf213 ring finger protein 213 JBrowse link 11 119,389,950 119,487,418 RGD:6480464
G Rny1 RNA, Y1 small cytoplasmic, Ro-associated JBrowse link 6 47,788,070 47,788,180 RGD:6480464
G Rny3 RNA, Y3 small cytoplasmic (associated with Ro protein) JBrowse link 6 47,781,624 47,781,724 RGD:6480464
G Ros1 Ros1 proto-oncogene JBrowse link 10 52,044,863 52,195,398 RGD:6480464
G Rpl34 ribosomal protein L34 JBrowse link 3 130,726,827 130,730,398 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 JBrowse link 11 86,498,869 86,544,885 RGD:6480464
G Rras related RAS viral (r-ras) oncogene JBrowse link 7 45,017,942 45,021,646 RGD:6480464
G Sat1 spermidine/spermine N1-acetyl transferase 1 JBrowse link X 155,213,126 155,216,449 RGD:6480464
G Scd2 stearoyl-Coenzyme A desaturase 2 JBrowse link 19 44,293,676 44,306,864 RGD:6480464
G Scnn1b sodium channel, nonvoltage-gated 1 beta JBrowse link 7 121,865,038 121,918,728 RGD:6480464
G Scnn1g sodium channel, nonvoltage-gated 1 gamma JBrowse link 7 121,734,420 121,768,482 RGD:6480464
G Sdc3 syndecan 3 JBrowse link 4 130,792,537 130,826,318 RGD:6480464
G Sesn2 sestrin 2 JBrowse link 4 132,492,804 132,510,456 RGD:6480464
G Sfn stratifin JBrowse link 4 133,600,556 133,602,168 RGD:6480464
G Sgk1 serum/glucocorticoid regulated kinase 1 JBrowse link 10 21,882,184 21,999,903 RGD:6480464
G Shh sonic hedgehog JBrowse link 5 28,456,840 28,467,101 RGD:6480464
G Sirt1 sirtuin 1 JBrowse link 10 63,319,005 63,339,035 RGD:6480464
G Slc25a14 solute carrier family 25 (mitochondrial carrier, brain), member 14 JBrowse link X 48,623,418 48,662,298 RGD:6480464
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 JBrowse link 8 71,568,728 71,587,307 RGD:6480464
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 JBrowse link 3 28,697,903 28,728,361 RGD:6480464
G Slc2a5 solute carrier family 2 (facilitated glucose transporter), member 5 JBrowse link 4 150,119,344 150,144,168 RGD:6480464
G Slc30a2 solute carrier family 30 (zinc transporter), member 2 JBrowse link 4 134,343,046 134,354,484 RGD:6480464
G Slc30a5 solute carrier family 30 (zinc transporter), member 5 JBrowse link 13 100,802,645 100,833,480 RGD:6480464
G Slc39a10 solute carrier family 39 (zinc transporter), member 10 JBrowse link 1 46,807,544 46,925,776 RGD:6480464
G Slc39a4 solute carrier family 39 (zinc transporter), member 4 JBrowse link 15 76,612,383 76,618,506 RGD:6480464
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 JBrowse link 19 8,706,882 8,723,369 RGD:6480464
G Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 JBrowse link 1 45,908,070 45,926,532 RGD:6480464
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 JBrowse link 3 50,364,936 50,499,087 RGD:6480464
G Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 JBrowse link 8 121,881,146 121,907,686 RGD:6480464
G Snca synuclein, alpha JBrowse link 6 60,731,573 60,829,855 RGD:6480464
G Socs3 suppressor of cytokine signaling 3 JBrowse link 11 117,966,079 117,970,336 RGD:6480464
G Sod2 superoxide dismutase 2, mitochondrial JBrowse link 17 13,007,839 13,018,119 RGD:6480464
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 JBrowse link 17 80,393,752 80,480,453 RGD:6480464
G Sox17 SRY (sex determining region Y)-box 17 JBrowse link 1 4,490,928 4,497,426 RGD:6480464
G Spata18 spermatogenesis associated 18 JBrowse link 5 73,651,380 73,679,584 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 11 50,200,152 50,210,820 RGD:6480464
G Stat1 signal transducer and activator of transcription 1 JBrowse link 1 52,119,438 52,161,865 RGD:6480464
G Stmn3 stathmin-like 3 JBrowse link 2 181,306,459 181,314,500 RGD:6480464
G Stom stomatin JBrowse link 2 35,313,990 35,337,009 RGD:6480464
G Sult1a1 sulfotransferase family 1A, phenol-preferring, member 1 JBrowse link 7 126,672,865 126,690,443 RGD:6480464
G Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) JBrowse link 17 34,187,556 34,197,225 RGD:6480464
G Tat tyrosine aminotransferase JBrowse link 8 109,986,078 109,999,804 RGD:6480464
G Tcf4 transcription factor 4 JBrowse link 18 69,343,429 69,687,967 RGD:6480464
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 3 81,958,412 81,975,728 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 7 25,687,002 25,705,077 RGD:6480464
G Tgfb2 transforming growth factor, beta 2 JBrowse link 1 186,622,787 186,709,697 RGD:6480464
G Thra thyroid hormone receptor alpha JBrowse link 11 98,740,776 98,769,006 RGD:6480464
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase JBrowse link 3 65,528,447 65,555,518 RGD:6480464
G Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 JBrowse link 1 50,900,683 51,187,270 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 17 35,199,367 35,202,007 RGD:6480464
G Tnfaip3 tumor necrosis factor, alpha-induced protein 3 JBrowse link 10 19,000,910 19,015,410 RGD:6480464
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b JBrowse link 14 69,767,472 69,784,411 RGD:6480464
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 JBrowse link 3 27,317,077 27,339,665 RGD:6480464
G Tnfsf9 tumor necrosis factor (ligand) superfamily, member 9 JBrowse link 17 57,105,287 57,107,758 RGD:6480464
G Top1 topoisomerase (DNA) I JBrowse link 2 160,645,897 160,722,764 RGD:6480464
G Trp53 transformation related protein 53 JBrowse link 11 69,580,348 69,591,873 RGD:6480464
G Trp53i11 transformation related protein 53 inducible protein 11 JBrowse link 2 93,187,349 93,201,757 RGD:6480464
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 JBrowse link 6 41,620,619 41,636,405 RGD:6480464
G Tuba4a tubulin, alpha 4A JBrowse link 1 75,214,972 75,221,261 RGD:6480464
G Txnrd1 thioredoxin reductase 1 JBrowse link 10 82,833,951 82,897,724 RGD:6480464
G Tymp thymidine phosphorylase JBrowse link 15 89,371,631 89,377,036 RGD:6480464
G Tyr tyrosinase JBrowse link 7 87,424,771 87,493,512 RGD:6480464
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 JBrowse link 16 17,152,015 17,201,512 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 3 116,110,020 116,129,688 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 17 46,016,993 46,032,377 RGD:6480464
G Vim vimentin JBrowse link 2 13,574,311 13,582,826 RGD:6480464
G Vmp1 vacuole membrane protein 1 JBrowse link 11 86,583,854 86,684,000 RGD:6480464
G Xiap X-linked inhibitor of apoptosis JBrowse link X 42,059,613 42,109,664 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 21021
    role 21002
      biological role 21000
        aetiopathogenetic role 19839
          genotoxin 16593
            mutagen 16200
              actinomycin D 290
Path 2
Term Annotations click to browse term
  CHEBI ontology 21021
    subatomic particle 21015
      composite particle 21015
        hadron 21015
          baryon 21015
            nucleon 21015
              atomic nucleus 21015
                atom 21015
                  main group element atom 20858
                    p-block element atom 20858
                      carbon group element atom 20599
                        carbon atom 20576
                          organic molecular entity 20576
                            organic group 19171
                              organic divalent group 19161
                                organodiyl group 19161
                                  carbonyl group 19133
                                    carbonyl compound 19133
                                      carboxylic acid 18811
                                        carboacyl group 17447
                                          univalent carboacyl group 17447
                                            carbamoyl group 17147
                                              carboxamide 17147
                                                peptide 9416
                                                  peptide antibiotic 1672
                                                    chromopeptide 290
                                                      actinomycin 290
                                                        actinomycin D 290
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.