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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cocaine
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Accession:CHEBI:27958 term browser browse the term
Definition:A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Synonyms:exact_synonym: (1R,2R,3S,5S)-2-(methoxycarbonyl)tropan-3-yl benzoate;   methyl (1R,2R,3S,5S)-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
 related_synonym: 2-methyl-3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester);   Benzoylmethylecgonine;   Cocain;   Cocaina;   Formula=C17H21NO4;   InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1;   InChIKey=ZPUCINDJVBIVPJ-LJISPDSOSA-N;   Kokain;   Neurocaine;   SMILES=[H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)c1ccccc1)C(=O)OC)N2C;   [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester;   beta-Cocain;   cocainum;   l-Cocain;   l-cocaine;   methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate;   methyl benzoylecgonine
 alt_id: CHEBI:23346;   CHEBI:3801;   CHEBI:41642
 xref: Beilstein:3621912;   Beilstein:5291037;   Beilstein:91034;   CAS:50-36-2;   DrugBank:DB00907;   Drug_Central:723;   Gmelin:170209;   KEGG:C01416;   KEGG:D00110;   KNApSAcK:C00002285
 xref_mesh: MESH:D003042
 xref: MetaCyc:CPD-9776;   PDBeChem:COC;   PMID:11416615;   PMID:11853120;   PMID:14962054;   PMID:17551070;   PMID:19536276;   PMID:21150772;   PMID:25303034;   Reaxys:5291037;   Reaxys:91034;   Wikipedia:Cocaine
 cyclic_relationship: is_conjugate_base_of CHEBI:60056


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cocaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression EXP Cocaine results in decreased expression of A2ML1 mRNA CTD PMID:27899881 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Aacs acetoacetyl-CoA synthetase affects expression EXP Cocaine affects the expression of AACS mRNA CTD PMID:20187946 NCBI chr12:36,512,393...36,555,694
Ensembl chr12:36,512,393...36,555,694
JBrowse link
G Aadac arylacetamide deacetylase decreases expression EXP Cocaine results in decreased expression of AADAC mRNA CTD PMID:17898221 NCBI chr 2:150,146,234...150,157,480
Ensembl chr 2:150,146,234...150,157,480
JBrowse link
G Aanat aralkylamine N-acetyltransferase affects response to substance ISO AANAT protein affects the susceptibility to Cocaine CTD PMID:12138020 NCBI chr10:105,568,091...105,572,407
Ensembl chr10:105,568,091...105,572,403
JBrowse link
G Abat 4-aminobutyrate aminotransferase increases response to substance ISO ABAT mRNA results in increased susceptibility to Cocaine CTD PMID:10850552 NCBI chr10:7,093,406...7,200,439
Ensembl chr10:7,093,405...7,200,499
JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 decreases expression EXP Cocaine results in decreased expression of ABCA4 mRNA CTD PMID:27899881 NCBI chr 2:225,645,539...225,783,288
Ensembl chr 2:225,645,568...225,783,287
JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ABCA5 mRNA] CTD PMID:17988634 NCBI chr10:98,573,226...98,645,028
Ensembl chr10:98,576,039...98,644,938
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 affects expression EXP Cocaine affects the expression of ABCC3 mRNA CTD PMID:20187946 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 affects expression EXP Cocaine affects the expression of ABCC5 mRNA CTD PMID:20187946 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 affects expression EXP Cocaine affects the expression of ABCC9 mRNA CTD PMID:20187946 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 affects expression EXP Cocaine affects the expression of ABCD4 mRNA CTD PMID:20187946 NCBI chr 6:108,315,026...108,329,550
Ensembl chr 6:108,315,035...108,329,464
JBrowse link
G Abhd1 abhydrolase domain containing 1 decreases expression ISO Cocaine results in decreased expression of ABHD1 mRNA CTD PMID:18355967 NCBI chr 6:26,787,807...26,792,795
Ensembl chr 6:26,784,058...26,792,808
JBrowse link
G Abhd14a abhydrolase domain containing 14A affects expression EXP Cocaine affects the expression of ABHD14A mRNA CTD PMID:20187946 NCBI chr 8:115,141,575...115,151,222
Ensembl chr 8:115,141,539...115,149,527
JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Cocaine affects the expression of ABHD17A mRNA CTD PMID:20187946 NCBI chr 7:11,992,543...12,000,978
Ensembl chr 7:11,992,543...11,998,973
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase affects expression ISO Cocaine affects the expression of ABL1 mRNA CTD PMID:15681117 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO Cocaine results in increased expression of ACAA1 mRNA CTD PMID:18355967 NCBI chr 8:127,836,235...127,845,296 JBrowse link
G Acan aggrecan affects expression EXP Cocaine affects the expression of ACAN mRNA CTD PMID:20187946 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions ISO ACE inhibits the reaction [Cocaine affects the abundance of Dinoprostone]; ACE inhibits the reaction [Cocaine affects the abundance of Epoprostenol] CTD PMID:14738173 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 affects expression ISO Cocaine affects the expression of ACIN1 mRNA CTD PMID:15681117 NCBI chr15:33,288,369...33,333,256
Ensembl chr15:33,288,374...33,333,417
JBrowse link
G Ackr2 atypical chemokine receptor 2 affects expression EXP Cocaine affects the expression of ACKR2 mRNA CTD PMID:20187946 NCBI chr 8:130,526,521...130,543,566
Ensembl chr 8:130,538,651...130,542,227
JBrowse link
G Aco2 aconitase 2 increases expression ISO Cocaine results in increased expression of ACO2 protein modified form CTD PMID:24096156 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acsl5 acyl-CoA synthetase long-chain family member 5 affects expression EXP Cocaine affects the expression of ACSL5 mRNA CTD PMID:20187946 NCBI chr 1:276,240,703...276,290,012
Ensembl chr 1:276,240,703...276,290,008
JBrowse link
G Acss1 acyl-CoA synthetase short-chain family member 1 decreases expression EXP Cocaine results in decreased expression of ACSS1 mRNA CTD PMID:27899881 NCBI chr 3:146,420,346...146,470,293
Ensembl chr 3:146,420,346...146,470,293
JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO Cocaine results in decreased expression of ACTG2 mRNA CTD PMID:20948987 NCBI chr 4:115,215,160...115,239,746
Ensembl chr 4:115,215,060...115,239,723
JBrowse link
G Actn2 actinin alpha 2 increases expression ISO Cocaine results in increased expression of ACTN2 mRNA CTD PMID:15009677, PMID:16710320 NCBI chr17:66,304,530...66,397,647
Ensembl chr17:66,304,501...66,397,653
JBrowse link
G Acvr1c activin A receptor type 1C increases expression EXP Cocaine results in increased expression of ACVR1C mRNA CTD PMID:17898221 NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355
JBrowse link
G Acy3 aminoacylase 3 affects expression EXP Cocaine affects the expression of ACY3 mRNA CTD PMID:20187946 NCBI chr 1:219,233,712...219,237,103
Ensembl chr 1:219,233,750...219,237,098
JBrowse link
G Adam19 ADAM metallopeptidase domain 19 decreases expression EXP Cocaine results in decreased expression of ADAM19 mRNA CTD PMID:17898221 NCBI chr10:31,146,107...31,240,582
Ensembl chr10:31,146,107...31,240,582
JBrowse link
G Adam1a ADAM metallopeptidase domain 1a multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ADAM1A mRNA] CTD PMID:17988634 NCBI chr12:40,533,731...40,536,632
Ensembl chr12:40,533,632...40,536,620
JBrowse link
G Adamts19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 decreases expression EXP Cocaine results in decreased expression of ADAMTS19 mRNA CTD PMID:27899881 NCBI chr18:53,915,807...54,099,856
Ensembl chr18:53,915,807...54,099,120
JBrowse link
G Adat2 adenosine deaminase, tRNA-specific 2 decreases expression EXP Cocaine results in decreased expression of ADAT2 mRNA CTD PMID:17898221 NCBI chr 1:7,726,447...7,743,112
Ensembl chr 1:7,726,529...7,742,484
JBrowse link
G Adcy2 adenylate cyclase 2 affects expression EXP Cocaine affects the expression of ADCY2 mRNA CTD PMID:20187946 NCBI chr 1:37,043,071...37,698,390
Ensembl chr 1:37,507,276...37,698,390
JBrowse link
G Adcy8 adenylate cyclase 8 affects expression EXP Cocaine affects the expression of ADCY8 mRNA CTD PMID:20187946 NCBI chr 7:105,353,883...105,593,372
Ensembl chr 7:105,353,913...105,592,804
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 increases expression
multiple interactions
ISO Cocaine results in increased expression of ADCYAP1 mRNA
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]
CTD PMID:29673861 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Adcyap1r1 ADCYAP receptor type I increases expression
multiple interactions
ISO Cocaine results in increased expression of ADCYAP1R1 mRNA
alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; TNF protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]
CTD PMID:29673861 NCBI chr 4:85,662,809...85,711,696
Ensembl chr 4:85,662,892...85,711,696
JBrowse link
G Adgra1 adhesion G protein-coupled receptor A1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA CTD PMID:18355967 NCBI chr 1:212,170,190...212,213,156
Ensembl chr 1:212,181,374...212,211,578
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 affects expression EXP Cocaine affects the expression of ADGRE1 mRNA CTD PMID:20187946 NCBI chr 9:9,431,888...9,585,883
Ensembl chr 9:9,431,860...9,585,865
JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression EXP Cocaine results in decreased expression of ADGRF1 mRNA CTD PMID:17898221 NCBI chr 9:20,343,730...20,378,686 JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 affects expression EXP Cocaine affects the expression of ADGRL1 mRNA CTD PMID:20187946 NCBI chr19:25,029,037...25,069,146
Ensembl chr19:25,029,037...25,069,142
JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 affects expression EXP Cocaine affects the expression of ADGRL3 mRNA CTD PMID:20187946 NCBI chr14:28,362,176...29,226,085
Ensembl chr14:28,393,394...28,967,980
JBrowse link
G Adora1 adenosine A1 receptor affects expression
affects response to substance
EXP
ISO
Cocaine affects the expression of ADORA1 mRNA; Cocaine affects the expression of ADORA1 protein
ADORA1 affects the susceptibility to Cocaine
CTD PMID:12358776, PMID:19092996 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor increases response to substance ISO ADORA2A results in increased susceptibility to Cocaine CTD PMID:16123743 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adora2b adenosine A2B receptor affects expression EXP Cocaine affects the expression of ADORA2B mRNA CTD PMID:20187946 NCBI chr10:48,569,563...48,586,366
Ensembl chr10:48,569,555...48,586,365
JBrowse link
G Adra1b adrenoceptor alpha 1B increases response to substance ISO ADRA1B gene results in increased susceptibility to Cocaine CTD PMID:14556232 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions
affects expression
EXP Betaxolol affects the reaction [Cocaine affects the expression of ADRB1 protein]; Betaxolol inhibits the reaction [Cocaine affects the expression of ADRB1 protein] CTD PMID:17513029, PMID:18596687 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Aff4 AF4/FMR2 family, member 4 increases expression EXP Cocaine results in increased expression of AFF4 mRNA CTD PMID:17898221 NCBI chr10:38,692,167...38,773,021
Ensembl chr10:38,692,211...38,773,021
JBrowse link
G Afmid arylformamidase increases expression EXP Cocaine results in increased expression of AFMID mRNA CTD PMID:17898221 NCBI chr10:106,828,963...106,844,314
Ensembl chr10:106,828,981...106,844,314
JBrowse link
G Afp alpha-fetoprotein increases expression EXP Cocaine results in increased expression of AFP mRNA CTD PMID:27899881 NCBI chr14:19,141,755...19,159,919
Ensembl chr14:19,141,755...19,159,923
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 affects expression EXP Cocaine affects the expression of AGAP2 mRNA CTD PMID:20187946 NCBI chr 7:70,360,199...70,377,422
Ensembl chr 7:70,364,813...70,377,422
JBrowse link
G Ago2 argonaute RISC catalytic component 2 multiple interactions
affects response to substance
ISO AGO2 protein affects the reaction [Cocaine results in increased expression of MIR130A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR136 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR137 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR138-1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR148B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR154 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR181A1 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR186 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR301B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR324 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR337 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR369 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376A mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR376C mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR380 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR384 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR467B mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR488 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR500 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR544 mRNA]; AGO2 protein affects the reaction [Cocaine results in increased expression of MIR665 mRNA]
AGO2 protein affects the susceptibility to Cocaine
CTD PMID:20643829 NCBI chr 7:114,339,607...114,377,277
Ensembl chr 7:114,339,434...114,380,613
JBrowse link
G Aif1l allograft inflammatory factor 1-like decreases expression ISO Cocaine results in decreased expression of AIF1L mRNA CTD PMID:15009677 NCBI chr 3:9,237,944...9,262,628
Ensembl chr 3:9,237,944...9,262,628
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects expression
increases expression
ISO Cocaine affects the expression of AIFM1 mRNA
Cocaine results in increased expression of AIFM1 mRNA
CTD PMID:15681117, PMID:18000554 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Aifm2 apoptosis inducing factor, mitochondria associated 2 affects expression ISO Cocaine affects the expression of AIFM2 mRNA CTD PMID:15681117 NCBI chr20:31,329,047...31,353,548
Ensembl chr20:31,339,787...31,352,906
JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Cocaine results in decreased expression of AK1 mRNA CTD PMID:15009677 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Ak3 adenylate kinase 3 affects expression EXP Cocaine affects the expression of AK3 mRNA CTD PMID:20187946 NCBI chr 1:247,144,486...247,169,690
Ensembl chr 1:247,144,491...247,169,693
JBrowse link
G Akr1d1 aldo-keto reductase family 1, member D1 affects expression EXP Cocaine affects the expression of AKR1D1 mRNA CTD PMID:20187946 NCBI chr 4:65,110,706...65,143,930
Ensembl chr 4:65,110,746...65,143,941
JBrowse link
G Akr1e2 aldo-keto reductase family 1, member E2 affects expression EXP Cocaine affects the expression of AKR1E1 mRNA CTD PMID:20187946 NCBI chr17:69,365,437...69,379,944
Ensembl chr17:69,365,453...69,379,947
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Cocaine affects the expression of AKR7A3 mRNA CTD PMID:20187946 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Akt1 AKT serine/threonine kinase 1 affects expression
multiple interactions
increases phosphorylation
EXP
ISO
Cocaine affects the expression of AKT1 mRNA
[Cocaine co-treated with cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester] results in increased phosphorylation of AKT1 protein
Cocaine results in increased phosphorylation of AKT1 protein
Cocaine affects the reaction [ILK protein affects the phosphorylation of AKT1 protein]
CTD PMID:18702665, PMID:20187946, PMID:25933444 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alcam activated leukocyte cell adhesion molecule increases expression EXP Cocaine results in increased expression of ALCAM mRNA CTD PMID:17898221 NCBI chr11:50,780,735...50,985,083
Ensembl chr11:50,781,127...50,985,083
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP [[CVT-10216 results in decreased activity of ALDH2 protein] which results in increased abundance of Tetrahydropapaveroline] inhibits the reaction [Cocaine results in increased abundance of and results in increased secretion of Dopamine]; [ALDH2 protein affects the abundance of Tetrahydropapaveroline] which affects the susceptibility to Cocaine; ALDH2 protein affects the reaction [Cocaine results in increased abundance of Dopamine] CTD PMID:20729865 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 decreases expression EXP Cocaine results in decreased expression of AMBRA1 mRNA CTD PMID:17898221 NCBI chr 3:80,634,470...80,830,068
Ensembl chr 3:80,634,470...80,830,068
JBrowse link
G Amh anti-Mullerian hormone increases expression EXP Cocaine results in increased expression of AMH mRNA CTD PMID:17898221 NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503
JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 affects expression EXP Cocaine affects the expression of AMIGO1 mRNA CTD PMID:20187946 NCBI chr 2:210,977,125...210,982,582
Ensembl chr 2:210,977,938...210,982,579
JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 affects expression EXP Cocaine affects the expression of AMIGO3 mRNA CTD PMID:20187946 NCBI chr 8:116,830,773...116,832,299 JBrowse link
G Amn1 antagonist of mitotic exit network 1 homolog decreases expression EXP Cocaine results in decreased expression of AMN1 mRNA CTD PMID:17898221 NCBI chr 4:183,670,589...183,697,531
Ensembl chr 4:183,670,596...183,697,531
JBrowse link
G Ankrd54 ankyrin repeat domain 54 affects expression EXP Cocaine affects the expression of ANKRD54 mRNA CTD PMID:20187946 NCBI chr 7:120,282,423...120,295,647
Ensembl chr 7:120,282,822...120,295,618
JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression EXP Cocaine results in decreased expression of ANKS1B mRNA CTD PMID:17898221 NCBI chr 7:30,507,135...31,684,604
Ensembl chr 7:30,699,476...31,681,182
JBrowse link
G Anxa7 annexin A7 affects expression EXP Cocaine affects the expression of ANXA7 mRNA CTD PMID:20187946 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
JBrowse link
G Ap1ar adaptor-related protein complex 1 associated regulatory protein increases expression EXP Cocaine results in increased expression of AP1AR mRNA CTD PMID:17898221 NCBI chr 2:232,146,418...232,178,813
Ensembl chr 2:232,147,690...232,178,671
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 affects expression EXP Cocaine affects the expression of AP2B1 mRNA CTD PMID:20187946 NCBI chr10:70,516,462...70,621,973
Ensembl chr10:70,520,206...70,621,977
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression EXP Cocaine results in increased expression of AP2M1 protein CTD PMID:25100957 NCBI chr11:84,041,184...84,047,542
Ensembl chr11:84,041,184...84,047,546
JBrowse link
G Ap2s1 adaptor related protein complex 2 subunit sigma 1 decreases expression ISO Cocaine results in decreased expression of AP2S1 mRNA CTD PMID:15009677 NCBI chr 1:78,671,238...78,682,847
Ensembl chr 1:78,671,121...78,682,871
JBrowse link
G Ap5m1 adaptor related protein complex 5 subunit mu 1 affects expression EXP Cocaine affects the expression of AP5M1 mRNA CTD PMID:20187946 NCBI chr15:25,933,483...25,955,745
Ensembl chr15:25,933,483...25,955,745
JBrowse link
G Apcs amyloid P component, serum increases expression ISO Cocaine results in increased expression of APCS protein CTD PMID:12714198 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575
JBrowse link
G Aph1a aph-1 homolog A, gamma secretase subunit affects expression EXP Cocaine affects the expression of APH1A mRNA CTD PMID:20187946 NCBI chr 2:198,006,247...198,009,837
Ensembl chr 2:198,006,316...198,009,830
JBrowse link
G Aplnr apelin receptor increases expression EXP Cocaine results in increased expression of APLNR mRNA CTD PMID:17898221 NCBI chr 3:72,540,538...72,544,183
Ensembl chr 3:72,540,538...72,544,182
JBrowse link
G Apol11a apolipoprotein L 11a decreases expression EXP Cocaine results in decreased expression of APOL11A mRNA CTD PMID:27899881 NCBI chr 7:118,835,316...118,858,347
Ensembl chr 7:118,836,547...118,840,634
JBrowse link
G Apold1 apolipoprotein L domain containing 1 affects expression EXP Cocaine affects the expression of APOLD1 mRNA CTD PMID:20187946 NCBI chr 4:168,752,142...168,755,024
Ensembl chr 4:168,752,133...168,755,023
JBrowse link
G Apoo apolipoprotein O increases expression EXP Cocaine results in increased expression of APOO protein CTD PMID:25100957 NCBI chr  X:63,521,033...63,625,134
Ensembl chr  X:63,520,991...63,625,134
JBrowse link
G App amyloid beta precursor protein decreases expression
increases expression
EXP
ISO
Cocaine results in decreased expression of APP mRNA
Cocaine results in increased expression of APP mRNA
CTD PMID:15009677, PMID:16710320, PMID:17898221 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 increases expression EXP Cocaine results in increased expression of APPL1 mRNA CTD PMID:17898221 NCBI chr16:2,560,103...2,602,035
Ensembl chr16:2,563,520...2,602,103
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein affects expression
increases expression
multiple interactions
EXP Cocaine affects the expression of ARC mRNA
Cocaine results in increased expression of ARC mRNA; Cocaine results in increased expression of ARC protein
Reserpine inhibits the reaction [Cocaine results in increased expression of ARC mRNA]
CTD PMID:7722525, PMID:12117546, PMID:15254092, PMID:17851536, PMID:18311559, PMID:18361437, PMID:20187946, PMID:24810662 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Arf4 ADP-ribosylation factor 4 decreases expression EXP Cocaine results in decreased expression of ARF4 protein CTD PMID:25100957 NCBI chr16:2,338,333...2,354,909
Ensembl chr16:2,338,333...2,354,909
JBrowse link
G Arhgap1 Rho GTPase activating protein 1 increases expression EXP Cocaine results in increased expression of ARHGAP1 protein CTD PMID:25100957 NCBI chr 3:80,555,196...80,576,881
Ensembl chr 3:80,555,196...80,576,856
JBrowse link
G Arhgap29 Rho GTPase activating protein 29 decreases expression ISO Cocaine results in decreased expression of ARHGAP29 mRNA CTD PMID:12629581 NCBI chr 2:225,552,075...225,613,349
Ensembl chr 2:225,552,148...225,613,359
JBrowse link
G Arhgap30 Rho GTPase activating protein 30 increases expression EXP Cocaine results in increased expression of ARHGAP30 mRNA CTD PMID:17898221 NCBI chr13:89,774,764...89,796,113
Ensembl chr13:89,774,764...89,796,113
JBrowse link
G Arhgap44 Rho GTPase activating protein 44 decreases expression EXP Cocaine results in decreased expression of ARHGAP44 protein CTD PMID:25100957 NCBI chr10:51,501,547...51,669,546
Ensembl chr10:51,502,894...51,669,297
JBrowse link
G Arhgap5 Rho GTPase activating protein 5 increases expression EXP Cocaine results in increased expression of ARHGAP5 mRNA CTD PMID:17898221 NCBI chr 6:73,345,129...73,408,304
Ensembl chr 6:73,345,392...73,405,880
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 decreases expression EXP Cocaine results in decreased expression of ARHGAP9 mRNA CTD PMID:17898221 NCBI chr 7:70,612,650...70,620,900
Ensembl chr 7:70,612,103...70,620,890
JBrowse link
G Arhgef1 Rho guanine nucleotide exchange factor 1 affects expression EXP Cocaine affects the expression of ARHGEF1 mRNA CTD PMID:20187946 NCBI chr 1:81,769,212...81,797,237
Ensembl chr 1:81,779,380...81,797,236
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 affects expression EXP Cocaine affects the expression of ARHGEF7 mRNA CTD PMID:20187946 NCBI chr16:83,006,732...83,117,065
Ensembl chr16:83,006,718...83,132,785
JBrowse link
G Armcx6 armadillo repeat containing, X-linked 6 affects expression EXP Cocaine affects the expression of ARMCX6 mRNA CTD PMID:20187946 NCBI chr  X:105,565,733...105,573,387
Ensembl chr  X:105,565,747...105,568,343
JBrowse link
G Arntl aryl hydrocarbon receptor nuclear translocator-like decreases expression ISO Cocaine results in decreased expression of ARNTL mRNA CTD PMID:15994025 NCBI chr 1:178,039,002...178,137,469
Ensembl chr 1:178,039,063...178,137,465
JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A increases expression EXP Cocaine results in increased expression of ARPC1A protein CTD PMID:25100957 NCBI chr12:11,272,609...11,294,084
Ensembl chr12:11,272,609...11,294,058
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 multiple interactions EXP Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP19 protein] CTD PMID:11268215 NCBI chr 8:81,949,577...81,972,054
Ensembl chr 8:81,949,877...81,968,589
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions EXP Cocaine inhibits the reaction [SK&F 81297 results in increased phosphorylation of ARPP21 protein] CTD PMID:11268215 NCBI chr 8:120,323,895...120,492,790
Ensembl chr 8:120,323,897...120,446,507
JBrowse link
G Art5 ADP-ribosyltransferase 5 increases expression EXP Cocaine results in increased expression of ART5 mRNA CTD PMID:17898221 NCBI chr 1:167,192,809...167,202,767
Ensembl chr 1:167,192,810...167,202,767
JBrowse link
G As3mt arsenite methyltransferase affects expression EXP Cocaine affects the expression of AS3MT mRNA CTD PMID:20187946 NCBI chr 1:266,482,787...266,514,570
Ensembl chr 1:266,482,858...266,514,569
JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 decreases expression EXP Cocaine results in decreased expression of ASAP1 mRNA CTD PMID:17898221 NCBI chr 7:104,670,076...104,951,090
Ensembl chr 7:104,669,672...104,801,045
JBrowse link
G Atad1 ATPase family, AAA domain containing 1 increases expression EXP Cocaine results in increased expression of ATAD1 mRNA CTD PMID:17898221 NCBI chr 1:251,234,702...251,386,996
Ensembl chr 1:251,235,508...251,387,002
JBrowse link
G Atad5 ATPase family, AAA domain containing 5 decreases expression EXP Cocaine results in decreased expression of ATAD5 mRNA CTD PMID:17898221 NCBI chr10:67,427,042...67,475,825
Ensembl chr10:67,427,066...67,473,649
JBrowse link
G Ate1 arginyltransferase 1 increases expression EXP Cocaine results in increased expression of ATE1 mRNA CTD PMID:17898221 NCBI chr 1:200,810,741...200,885,593
NCBI chr 1:200,958,564...201,082,100
Ensembl chr 1:200,810,771...201,082,727
JBrowse link
G Atf3 activating transcription factor 3 increases expression
decreases expression
EXP Cocaine results in increased expression of ATF3 mRNA
Cocaine results in decreased expression of ATF3 mRNA
CTD PMID:23644055, PMID:27899881 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 increases expression EXP Cocaine results in increased expression of ATF4; Cocaine results in increased expression of ATF4 mRNA CTD PMID:18593214, PMID:23644055 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 affects expression EXP Cocaine affects the expression of ATF6 mRNA CTD PMID:23644055 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atf7 activating transcription factor 7 affects expression ISO Cocaine affects the expression of ATF7 mRNA CTD PMID:15681117 NCBI chr 7:144,131,382...144,223,463
Ensembl chr 7:144,136,325...144,223,429
JBrowse link
G Atg2b autophagy related 2B affects expression EXP Cocaine affects the expression of ATG2B mRNA CTD PMID:20187946 NCBI chr 6:129,449,451...129,519,599
Ensembl chr 6:129,449,449...129,509,720
JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase affects expression EXP Cocaine affects the expression of ATG4B mRNA CTD PMID:20187946 NCBI chr 9:100,888,457...100,920,123
Ensembl chr 9:100,888,501...100,918,637
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases expression
ISO EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA] CTD PMID:20056891 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp10a ATPase phospholipid transporting 10A (putative) decreases expression EXP Cocaine results in decreased expression of ATP10A mRNA CTD PMID:17898221, PMID:27899881 NCBI chr 1:115,973,343...116,141,892
Ensembl chr 1:115,975,324...116,141,892
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 affects expression ISO Cocaine affects the expression of ATP1A1 mRNA CTD PMID:18355967 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 increases expression
affects expression
EXP Cocaine results in increased expression of ATP1A3 mRNA
Cocaine affects the expression of ATP1A3 mRNA
CTD PMID:16076954, PMID:20187946 NCBI chr 1:81,852,423...81,881,565
Ensembl chr 1:81,852,429...81,881,549
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 increases expression EXP Cocaine results in increased expression of ATP1B2 mRNA CTD PMID:16076954 NCBI chr10:56,205,622...56,211,879
Ensembl chr10:56,205,625...56,211,891
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression
multiple interactions
ISO Cocaine results in increased expression of ATP1B3 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]
CTD PMID:18355967 NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha affects expression ISO Cocaine affects the expression of ATP5F1A protein CTD PMID:19393250 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression ISO Cocaine results in decreased expression of ATP5F1B protein CTD PMID:17075605 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Cocaine affects the expression of ATP5F1E mRNA CTD PMID:20187946 NCBI chr 3:172,563,105...172,566,007
Ensembl chr 3:172,563,105...172,566,010
JBrowse link
G Atp5mc3 ATP synthase membrane subunit c locus 3 decreases expression
affects expression
ISO
EXP
Cocaine results in decreased expression of ATP5MC3 mRNA
Cocaine affects the expression of ATP5MC3 mRNA
CTD PMID:12629581, PMID:20187946 NCBI chr 3:60,811,218...60,813,903
Ensembl chr 3:60,811,210...60,813,869
JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b affects expression EXP Cocaine affects the expression of ATP5PB mRNA CTD PMID:20187946 NCBI chr 2:208,566,385...208,577,147
Ensembl chr 2:208,566,385...208,577,146
JBrowse link
G Atp5pd ATP synthase peripheral stalk subunit d affects expression EXP Cocaine affects the expression of ATP5H mRNA CTD PMID:12358776 NCBI chr10:103,967,340...103,972,552
Ensembl chr10:103,967,312...103,972,668
JBrowse link
G Atp6v1d ATPase H+ transporting V1 subunit D affects expression EXP Cocaine affects the expression of ATP6V1D mRNA CTD PMID:20187946 NCBI chr 6:102,032,271...102,047,754
Ensembl chr 6:102,032,276...102,047,758
JBrowse link
G Atp8b2 ATPase phospholipid transporting 8B2 increases expression
multiple interactions
ISO Cocaine results in increased expression of ATP8B2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]
CTD PMID:18355967 NCBI chr 2:189,285,961...189,306,947
Ensembl chr 2:189,285,953...189,307,108
JBrowse link
G Atp9b ATPase phospholipid transporting 9B (putative) affects response to substance ISO ATP9B gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr18:77,343,551...77,535,608
Ensembl chr18:77,343,551...77,535,593
JBrowse link
G Atpaf1 ATP synthase mitochondrial F1 complex assembly factor 1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA CTD PMID:18355967 NCBI chr 5:134,641,618...134,667,079
Ensembl chr 5:134,641,608...134,667,084
JBrowse link
G Atrx ATRX, chromatin remodeler increases expression EXP Cocaine results in increased expression of ATRX mRNA CTD PMID:17898221 NCBI chr  X:76,820,110...76,979,155
Ensembl chr  X:76,692,970...76,708,878
Ensembl chr  X:76,692,970...76,708,878
JBrowse link
G Atxn1 ataxin 1 affects expression EXP Cocaine affects the expression of ATXN1 mRNA CTD PMID:20187946 NCBI chr17:19,160,986...19,533,814
Ensembl chr17:19,249,952...19,533,814
JBrowse link
G Atxn3 ataxin 3 decreases expression ISO Cocaine results in decreased expression of ATXN3 mRNA CTD PMID:12629581 NCBI chr 6:125,817,420...125,853,461
Ensembl chr 6:125,819,640...125,853,461
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression EXP Cocaine results in decreased expression of AZGP1 mRNA CTD PMID:17898221 NCBI chr12:19,196,565...19,203,094
Ensembl chr12:19,196,611...19,202,647
JBrowse link
G Baalc BAALC binder of MAP3K1 and KLF4 decreases expression ISO Cocaine results in decreased expression of BAALC mRNA CTD PMID:18355967 NCBI chr 7:77,761,056...77,836,534
Ensembl chr 7:77,763,512...77,837,453
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression EXP Cocaine results in increased expression of BACH1 mRNA CTD PMID:17898221 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bach2 BTB domain and CNC homolog 2 affects expression ISO Cocaine affects the expression of BACH2 mRNA CTD PMID:15681117 NCBI chr 5:47,458,891...47,807,176
Ensembl chr 5:47,546,014...47,807,166
JBrowse link
G Bad BCL2-associated agonist of cell death affects expression ISO Cocaine affects the expression of BAD mRNA CTD PMID:15681117 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag1 BAG cochaperone 1 affects expression ISO Cocaine affects the expression of BAG1 mRNA CTD PMID:15681117 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bag3 BAG cochaperone 3 affects expression
increases expression
ISO
EXP
Cocaine affects the expression of BAG3 mRNA
Cocaine results in increased expression of BAG3 mRNA
CTD PMID:15681117, PMID:27899881 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor affects expression EXP Cocaine affects the expression of BAMBI mRNA CTD PMID:20187946 NCBI chr17:56,905,419...56,909,675
Ensembl chr17:56,905,112...56,909,992
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 affects expression EXP Cocaine affects the expression of BASP1 mRNA CTD PMID:20187946 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
increases activity
affects expression
ISO
EXP
Cocaine results in increased expression of BAX mRNA
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased expression of BAX protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased expression of BAX protein]; IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [Cocaine results in increased expression of BAX protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]]
Cocaine results in increased activity of BAX protein
Cocaine affects the expression of BAX mRNA
CTD PMID:11392460, PMID:15681117, PMID:15685203, PMID:17084983, PMID:17635674, PMID:18974856, PMID:20948987, PMID:29673861, PMID:30393195 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions
increases expression
ISO [SMARCA5 protein co-treated with BAZ1B protein] results in increased susceptibility to Cocaine; Cocaine promotes the reaction [BAZ1B protein binds to SPHKAP gene]; Cocaine results in increased expression of and affects the activity of BAZ1B protein
Cocaine results in increased expression of BAZ1B mRNA
CTD PMID:27053203 NCBI chr12:24,478,882...24,536,851
Ensembl chr12:24,478,898...24,537,313
JBrowse link
G Baz2b bromodomain adjacent to zinc finger domain, 2B increases expression EXP Cocaine results in increased expression of BAZ2B mRNA CTD PMID:17898221 NCBI chr 3:45,968,845...46,286,915
Ensembl chr 3:45,968,825...46,153,371
JBrowse link
G Bcap31 B-cell receptor-associated protein 31 affects expression EXP Cocaine affects the expression of BCAP31 mRNA CTD PMID:20187946 NCBI chr  X:157,094,365...157,126,397
Ensembl chr  X:157,095,937...157,126,393
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 affects expression EXP Cocaine affects the expression of BCAT1 mRNA CTD PMID:20187946 NCBI chr 4:179,259,305...179,340,021
Ensembl chr 4:179,259,308...179,339,795
JBrowse link
G Bche butyrylcholinesterase affects metabolic processing
multiple interactions
increases hydrolysis
increases metabolic processing
decreases response to substance
affects hydrolysis
decreases metabolic processing
affects degradation
ISO BCHE protein affects the metabolism of Cocaine
[BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of Benzoic Acid; [BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of ecgonine methyl ester
[BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of Benzoic Acid; [BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of ecgonine methyl ester
BCHE protein mutant form results in increased metabolism of Cocaine; BCHE protein results in increased metabolism of Cocaine
BCHE protein mutant form results in decreased susceptibility to Cocaine
BCHE protein modified form results in increased hydrolysis of Cocaine; BCHE protein mutant form results in increased hydrolysis of Cocaine
BCHE protein affects the hydrolysis of Cocaine
BCHE protein mutant form results in decreased metabolism of Cocaine
BCHE protein mutant form affects the degradation of Cocaine
CTD PMID:572161, PMID:16275916, PMID:17989928, PMID:18514178, PMID:18514640, PMID:19067679, PMID:20060817, PMID:20219449, PMID:20971807, PMID:22917637, PMID:22960160, PMID:24582612, PMID:25814464, PMID:27154495, PMID:30080993 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bcl2 BCL2, apoptosis regulator affects expression
multiple interactions
decreases expression
increases phosphorylation
increases expression
ISO
EXP
Cocaine affects the expression of BCL2 mRNA
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]]
Cocaine results in increased phosphorylation of BCL2 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; 7-(hydroxyimino)cyclopropan(b)chromen-1a-carbxoylic acid ethyl ester inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]
Cocaine results in decreased expression of BCL2 mRNA; Cocaine results in decreased expression of BCL2 protein
Cocaine results in increased expression of BCL2 protein
CTD PMID:11392460, PMID:15365088, PMID:15681117, PMID:15685203, PMID:17084983, PMID:18974856, PMID:19183502, PMID:19879923, PMID:29673861, PMID:30393195 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
decreases expression
multiple interactions
EXP
ISO
Cocaine results in increased expression of BCL2L1 mRNA; Cocaine results in increased expression of BCL2L1 mRNA alternative form
Cocaine results in decreased expression of BCL2L1 protein
IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; rottlerin inhibits the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]]
CTD PMID:16076954, PMID:29673861, PMID:30393195 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression EXP Cocaine results in increased expression of BCL2L11 mRNA CTD PMID:16076954 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bdnf brain-derived neurotrophic factor decreases response to substance
increases expression
decreases activity
affects expression
multiple interactions
decreases expression
increases response to substance
ISO
EXP
BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine
Cocaine results in increased expression of BDNF mRNA
Cocaine results in decreased activity of BDNF protein
Cocaine results in increased expression of BDNF protein
Cocaine affects the expression of BDNF exon; Cocaine affects the expression of BDNF mRNA; Cocaine affects the expression of BDNF protein
BDNF protein inhibits the reaction [Cocaine results in increased abundance of Amino Acids, Peptides, and Proteins]; Cocaine affects the activity of and affects the expression of BDNF protein; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine affects the reaction [MECP2 protein affects the expression of BDNF protein]; Cocaine affects the reaction [MECP2 protein binds to and results in decreased activity of BDNF promoter]; Cocaine affects the reaction [MIR212 protein affects the expression of BDNF protein]
BDNF mRNA results in decreased susceptibility to Cocaine; BDNF protein results in decreased susceptibility to Cocaine; BDNF results in decreased susceptibility to Cocaine
(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; (+)-JQ1 compound inhibits the reaction [Cocaine results in increased expression of BDNF mRNA]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; Cocaine inhibits the reaction [MECP2 protein binds to BDNF promoter]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
Cocaine results in decreased expression of BDNF mRNA; Cocaine results in decreased expression of BDNF protein
BDNF results in increased susceptibility to Cocaine
CTD PMID:12099907, PMID:14973246, PMID:16423334, PMID:17194538, PMID:17618281, PMID:18311559, PMID:18355967, PMID:19321768, PMID:20554863, PMID:20711185, PMID:20810894, PMID:20826313, PMID:24358339, PMID:26558777 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Begain brain-enriched guanylate kinase-associated affects expression EXP Cocaine affects the expression of BEGAIN mRNA CTD PMID:20187946 NCBI chr 6:132,936,964...132,972,569
Ensembl chr 6:132,936,970...132,972,511
JBrowse link
G Bhlhe22 basic helix-loop-helix family, member e22 increases expression EXP Cocaine results in increased expression of BHLHE22 mRNA CTD PMID:17898221 NCBI chr 2:102,685,513...102,688,624
Ensembl chr 2:102,685,513...102,688,624
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression EXP Cocaine affects the expression of BHLHE40 mRNA CTD PMID:20187946 NCBI chr 4:140,703,619...140,709,319
Ensembl chr 4:140,703,619...140,709,319
JBrowse link
G Bid BH3 interacting domain death agonist affects expression ISO Cocaine affects the expression of BID mRNA CTD PMID:15681117 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bik BCL2-interacting killer affects expression ISO Cocaine affects the expression of BIK mRNA CTD PMID:15681117 NCBI chr 7:124,390,924...124,410,449
Ensembl chr 7:124,391,432...124,410,447
JBrowse link
G Bmp2k BMP-2 inducible kinase affects expression EXP Cocaine affects the expression of BMP2K mRNA CTD PMID:20187946 NCBI chr14:14,126,086...14,226,823
Ensembl chr14:14,129,725...14,192,048
JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 increases expression EXP Cocaine results in increased expression of BMPR2 mRNA CTD PMID:17898221 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Bnip2 BCL2 interacting protein 2 affects expression ISO Cocaine affects the expression of BNIP2 mRNA CTD PMID:15681117 NCBI chr 8:76,400,333...76,426,307
Ensembl chr 8:76,400,341...76,426,503
JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression ISO Cocaine affects the expression of BNIP3 mRNA CTD PMID:15681117 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bnip3l BCL2 interacting protein 3 like affects expression ISO Cocaine affects the expression of BNIP3L mRNA CTD PMID:15681117 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Brd4 bromodomain containing 4 multiple interactions
increases expression
ISO
EXP
(+)-JQ1 compound inhibits the reaction [Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]]; Cocaine promotes the reaction [BRD4 protein binds to BDNF promoter]
Cocaine results in increased expression of BRD4 protein
CTD PMID:26558777 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin affects expression EXP Cocaine affects the expression of BSCL2 mRNA CTD PMID:20187946 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G Bst1 bone marrow stromal cell antigen 1 affects expression EXP Cocaine affects the expression of BST1 mRNA CTD PMID:20187946 NCBI chr14:71,798,218...71,814,540
Ensembl chr14:71,798,651...71,814,523
JBrowse link
G Btbd9 BTB domain containing 9 increases expression EXP Cocaine results in increased expression of BTBD9 mRNA CTD PMID:17898221 NCBI chr20:8,899,286...9,253,936
Ensembl chr20:8,901,931...9,249,820
JBrowse link
G Btg2 BTG anti-proliferation factor 2 affects expression EXP Cocaine affects the expression of BTG2 mRNA CTD PMID:20187946 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Btk Bruton tyrosine kinase decreases expression EXP Cocaine results in decreased expression of BTK mRNA CTD PMID:17898221 NCBI chr  X:105,360,922...105,390,580
Ensembl chr  X:105,360,922...105,390,580
JBrowse link
G C1qbp complement C1q binding protein decreases expression EXP Cocaine results in decreased expression of C1QBP protein CTD PMID:25100957 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G C1qtnf1 C1q and TNF related 1 affects expression EXP Cocaine affects the expression of C1QTNF1 mRNA CTD PMID:20187946 NCBI chr10:107,455,845...107,477,160
Ensembl chr10:107,455,845...107,477,162
JBrowse link
G C1qtnf4 C1q and TNF related 4 decreases expression EXP Cocaine results in decreased expression of C1QTNF4 mRNA CTD PMID:17898221 NCBI chr 3:79,713,580...79,718,018
Ensembl chr 3:79,713,567...79,718,025
JBrowse link
G C2cd3 C2 domain containing 3 centriole elongation regulator decreases expression EXP Cocaine results in decreased expression of C2CD3 mRNA CTD PMID:17898221 NCBI chr 1:165,382,279...165,480,088
Ensembl chr 1:165,382,690...165,479,655
JBrowse link
G C2cd4d C2 calcium-dependent domain containing 4D decreases expression EXP Cocaine results in decreased expression of C2CD4D mRNA CTD PMID:27899881 NCBI chr 2:195,599,706...195,604,730
Ensembl chr 2:195,603,599...195,604,624
JBrowse link
G Ca4 carbonic anhydrase 4 decreases expression EXP Cocaine results in decreased expression of CAR4 mRNA CTD PMID:17898221 NCBI chr10:72,272,286...72,281,069
Ensembl chr10:72,272,248...72,281,067
JBrowse link
G Cab39l calcium binding protein 39-like multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA CTD PMID:18355967 NCBI chr15:39,745,124...39,849,022
Ensembl chr15:39,759,257...39,870,208
JBrowse link
G Cacna1d calcium voltage-gated channel subunit alpha1 D affects response to substance ISO CACNA1D polymorphism affects the susceptibility to Cocaine CTD PMID:28194001 NCBI chr16:6,110,294...6,405,022
Ensembl chr16:6,112,150...6,405,117
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 affects expression EXP Cocaine affects the expression of CACNB3 mRNA CTD PMID:20187946 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Cald1 caldesmon 1 affects expression EXP Cocaine affects the expression of CALD1 mRNA CTD PMID:20187946 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Calm1 calmodulin 1 decreases expression ISO Cocaine results in decreased expression of CALM1 mRNA CTD PMID:17205118 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 decreases expression ISO Cocaine results in decreased expression of CALM2 mRNA CTD PMID:17205118 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Calr calreticulin decreases expression
multiple interactions
affects expression
ISO
EXP
Cocaine results in decreased expression of CALR mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]
Cocaine affects the expression of CALR mRNA
CTD PMID:18355967, PMID:20187946 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Caly calcyon neuron-specific vesicular protein increases expression EXP Cocaine results in increased expression of CALY mRNA CTD PMID:20171207 NCBI chr 1:212,537,851...212,549,040
Ensembl chr 1:212,537,848...212,549,477
JBrowse link
G Camk1g calcium/calmodulin-dependent protein kinase IG multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA CTD PMID:18355967 NCBI chr13:112,075,689...112,099,472
Ensembl chr13:112,075,690...112,099,336
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha affects response to substance
multiple interactions
increases expression
ISO
EXP
CAMK2A affects the susceptibility to Cocaine
Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of CAMK2A protein]
Cocaine results in increased expression of CAMK2A protein
7-chlorokynurenic acid inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]; Sodium Benzoate promotes the reaction [Cocaine results in increased phosphorylation of and results in increased activity of CAMK2A protein]
CTD PMID:14725635, PMID:17609678, PMID:19217379, PMID:28194001 NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression
affects expression
ISO
EXP
Cocaine results in decreased expression of CAMK2B mRNA
Cocaine affects the expression of CAMK2B mRNA
CTD PMID:17205118, PMID:20187946 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases response to substance
decreases response to substance
ISO CAMK4 promoter SNP results in increased susceptibility to Cocaine
CAMK4 protein results in decreased susceptibility to Cocaine
CTD PMID:19001277 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 affects expression EXP Cocaine affects the expression of CAP2 mRNA CTD PMID:20187946 NCBI chr17:18,441,614...18,592,866
Ensembl chr17:18,442,127...18,592,750
JBrowse link
G Capzb capping actin protein of muscle Z-line subunit beta decreases expression ISO Cocaine results in decreased expression of CAPZB mRNA CTD PMID:12629581 NCBI chr 5:157,642,742...157,742,487
Ensembl chr 5:157,642,751...157,742,478
JBrowse link
G Card11 caspase recruitment domain family, member 11 decreases expression EXP Cocaine results in decreased expression of CARD11 mRNA CTD PMID:27899881 NCBI chr12:15,700,600...15,844,512
Ensembl chr12:15,700,825...15,844,512
JBrowse link
G Carm1 coactivator-associated arginine methyltransferase 1 affects expression EXP Cocaine affects the expression of CARM1 mRNA CTD PMID:20187946 NCBI chr 8:22,577,723...22,622,555
Ensembl chr 8:22,577,715...22,622,560
JBrowse link
G Carnmt1 carnosine N-methyltransferase 1 affects expression EXP Cocaine affects the expression of CARNMT1 mRNA CTD PMID:20187946 NCBI chr 1:234,675,442...234,704,856
Ensembl chr 1:234,677,692...234,704,792
JBrowse link
G Cartpt CART prepropeptide increases expression
affects expression
ISO
EXP
Cocaine results in increased expression of CARTPT mRNA
Cocaine affects the expression of CARTPT mRNA
CTD PMID:15009677, PMID:17851536, PMID:20187946 NCBI chr 2:30,125,249...30,127,408
Ensembl chr 2:30,125,249...30,127,269
JBrowse link
G Casp2 caspase 2 increases activity
increases expression
EXP Cocaine results in increased activity of CASP2 protein
Cocaine results in increased expression of CASP2 mRNA
CTD PMID:16076954, PMID:16638611 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 increases expression
increases cleavage
multiple interactions
increases activity
affects expression
ISO
EXP
Cocaine results in increased expression of CASP3 protein
Cocaine results in increased cleavage of CASP3 protein
ADCYAP1 protein modified form affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; PRKCD protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; rottlerin inhibits the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]]
Cocaine results in increased activity of CASP3 protein
Cocaine affects the expression of CASP3 protein
[Heroin co-treated with Cocaine] results in increased activity of CASP3 protein; Cocaine results in increased cleavage of and results in increased activity of CASP3 protein; Heroin promotes the reaction [Cocaine results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP3 protein]
Cocaine affects the expression of CASP3 mRNA
CTD PMID:10604926, PMID:11392460, PMID:12639677, PMID:14741756, PMID:15365088, PMID:15681117, PMID:16179556, PMID:16638611, PMID:16686379, PMID:17084983, PMID:17635674, PMID:18974856, PMID:19183502, PMID:20600547, PMID:29673861, PMID:30393195 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 affects expression
decreases expression
ISO Cocaine affects the expression of CASP4 mRNA
Cocaine results in decreased expression of CASP4 mRNA
CTD PMID:12629581, PMID:15681117 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Casp8 caspase 8 affects expression
increases activity
ISO
EXP
Cocaine affects the expression of CASP8 mRNA
Cocaine results in increased activity of CASP8 protein
CTD PMID:11392460, PMID:15681117, PMID:18974856 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 affects expression
increases activity
multiple interactions
increases expression
ISO
EXP
Cocaine affects the expression of CASP9 mRNA
Cocaine results in increased activity of CASP9 protein
SB 203580 inhibits the reaction [Cocaine results in increased activity of CASP9 protein]
Cocaine affects the expression of CASP9 protein
Cocaine results in increased expression of CASP9 protein
CTD PMID:10604926, PMID:11392460, PMID:12639677, PMID:15365088, PMID:15681117, PMID:16179556, PMID:16638611, PMID:16686379, PMID:17084983, PMID:17635674, PMID:18974856 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 affects expression EXP Cocaine affects the expression of CASTOR1 mRNA CTD PMID:20187946 NCBI chr14:84,447,552...84,457,396
Ensembl chr14:84,447,885...84,452,367
JBrowse link
G Cat catalase decreases activity
increases activity
increases expression
ISO
EXP
Cocaine results in decreased activity of CAT protein
Cocaine results in increased activity of CAT protein
Cocaine results in increased expression of CAT protein
CTD PMID:14576513, PMID:16085363, PMID:29475069 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Catsper2 cation channel, sperm associated 2 increases expression EXP Cocaine results in increased expression of CATSPER2 mRNA CTD PMID:17898221 NCBI chr 3:113,357,361...113,379,498
Ensembl chr 3:113,357,365...113,376,751
JBrowse link
G Cbln1 cerebellin 1 precursor multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA CTD PMID:18355967 NCBI chr19:20,607,507...20,611,316
Ensembl chr19:20,607,507...20,611,316
JBrowse link
G Ccdc127 coiled-coil domain containing 127 increases expression EXP Cocaine results in increased expression of CCDC127 mRNA CTD PMID:17898221 NCBI chr 1:31,538,088...31,545,573
Ensembl chr 1:31,539,215...31,545,559
JBrowse link
G Ccdc174 coiled-coil domain containing 174 affects expression EXP Cocaine affects the expression of CCDC174 mRNA CTD PMID:20187946 NCBI chr 4:123,760,708...123,787,529
Ensembl chr 4:123,760,743...123,787,528
JBrowse link
G Ccdc73 coiled-coil domain containing 73 decreases expression EXP Cocaine results in decreased expression of CCDC73 mRNA CTD PMID:17898221 NCBI chr 3:94,848,775...94,989,984
Ensembl chr 3:94,848,823...94,986,263
JBrowse link
G Ccdc88a coiled coil domain containing 88A increases expression EXP Cocaine results in increased expression of CCDC88A mRNA CTD PMID:17898221 NCBI chr14:113,771,093...113,936,376
Ensembl chr14:113,867,209...113,932,263
JBrowse link
G Ccdc93 coiled-coil domain containing 93 increases expression EXP Cocaine results in increased expression of CCDC93 mRNA CTD PMID:17898221 NCBI chr13:37,400,455...37,473,973
Ensembl chr13:37,400,476...37,468,840
JBrowse link
G Cckbr cholecystokinin B receptor decreases expression
increases response to substance
ISO Cocaine results in decreased expression of CCKBR mRNA
CCKBR protein results in increased susceptibility to Cocaine
CTD PMID:11403953, PMID:18000554 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion
increases expression
multiple interactions
ISO
EXP
Cocaine results in increased secretion of CCL2 protein
Cocaine results in increased expression of CCL2 mRNA; Cocaine results in increased expression of CCL2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; AG 1879 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; Cocaine promotes the reaction [RELA protein binds to CCL2 promoter]; methyl-beta-cyclodextrin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; N-(2-(3,4-Dichlorphenyl)ethyl)-N,N',N'-trimethyl-1,2-ethandiamin inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; pyrazolanthrone inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; RELA mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SC 514 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; SIGMAR1 mutant form inhibits the reaction [Cocaine results in increased expression of CCL2 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of CCL2 protein]
CTD PMID:10065903, PMID:20354174 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases secretion ISO Cocaine results in increased secretion of CCL3 protein CTD PMID:10065903 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Cocaine results in decreased expression of CCN2 mRNA; Cocaine results in decreased expression of CCN2 protein CTD PMID:18000554 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccn3 cellular communication network factor 3 increases expression EXP Cocaine results in increased expression of CCN3 mRNA CTD PMID:17898221 NCBI chr 7:94,375,134...94,382,154
Ensembl chr 7:94,375,020...94,383,024
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO
EXP
Cocaine results in decreased expression of CCNA2 mRNA CTD PMID:18593214 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 affects expression EXP Cocaine affects the expression of CCND1 mRNA CTD PMID:20187946 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 affects expression EXP Cocaine affects the expression of CCND3 mRNA CTD PMID:20187946 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Cocaine results in increased expression of CCNL1 mRNA CTD PMID:16076954 NCBI chr 2:157,747,295...157,759,838
Ensembl chr 2:157,747,542...157,759,838
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 affects expression
increases response to substance
EXP
ISO
Cocaine affects the expression of CCR2 mRNA
CCR2 results in increased susceptibility to Cocaine
CTD PMID:20187946, PMID:20354174
G Ccr5 C-C motif chemokine receptor 5 increases expression ISO Cocaine results in increased expression of CCR5 protein CTD PMID:16204638 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Ccser1 coiled-coil serine-rich protein 1 affects response to substance ISO CCSER1 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 4:91,235,885...92,516,800
Ensembl chr 4:91,373,942...91,972,325
JBrowse link
G Cct2 chaperonin containing TCP1 subunit 2 affects expression EXP Cocaine affects the expression of CCT2 mRNA CTD PMID:20187946 NCBI chr 7:60,106,532...60,122,779
Ensembl chr 7:60,109,974...60,122,805
JBrowse link
G Cd180 CD180 molecule decreases expression EXP Cocaine results in decreased expression of CD180 mRNA CTD PMID:27899881 NCBI chr 2:32,820,275...32,833,223
Ensembl chr 2:32,820,322...32,833,125
JBrowse link
G Cd276 Cd276 molecule affects expression EXP Cocaine affects the expression of CD276 mRNA CTD PMID:20187946 NCBI chr 8:63,312,060...63,350,411
Ensembl chr 8:63,318,019...63,350,269
JBrowse link
G Cd4 Cd4 molecule multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA CTD PMID:18355967 NCBI chr 4:157,381,862...157,408,357
Ensembl chr 4:157,383,052...157,408,176
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression ISO Cocaine results in decreased expression of CD44 mRNA CTD PMID:18000554 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd47 Cd47 molecule affects expression EXP Cocaine affects the expression of CD47 mRNA CTD PMID:20187946 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
G Cd74 CD74 molecule affects expression EXP Cocaine affects the expression of CD74 mRNA CTD PMID:20187946 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cd81 Cd81 molecule increases response to substance
increases expression
affects response to substance
ISO
EXP
CD81 protein results in increased susceptibility to Cocaine
Cocaine results in increased expression of CD81 mRNA
CD81 protein affects the susceptibility to Cocaine
CTD PMID:11178868, PMID:12113778, PMID:15715673 NCBI chr 1:216,237,663...216,253,460
Ensembl chr 1:216,237,697...216,253,311
JBrowse link
G Cd93 CD93 molecule decreases expression EXP Cocaine results in decreased expression of CD93 mRNA CTD PMID:17898221 NCBI chr 3:142,778,798...142,783,774
Ensembl chr 3:142,778,770...142,783,774
JBrowse link
G Cdc14b cell division cycle 14B decreases expression EXP Cocaine results in decreased expression of CDC14B mRNA CTD PMID:17898221 NCBI chr17:1,709,703...1,797,732
Ensembl chr17:1,703,943...1,797,750
JBrowse link
G Cdc25a cell division cycle 25A increases expression EXP Cocaine results in increased expression of CDC25A mRNA CTD PMID:17898221 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO Cocaine results in decreased expression of CDH1 mRNA CTD PMID:12629581 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh16 cadherin 16 affects expression EXP Cocaine affects the expression of CDH16 mRNA CTD PMID:20187946 NCBI chr19:568,329...578,513
Ensembl chr19:568,287...578,520
JBrowse link
G Cdh17 cadherin 17 decreases expression ISO Cocaine results in decreased expression of CDH17 mRNA CTD PMID:12629581 NCBI chr 5:25,354,187...25,443,675
Ensembl chr 5:25,391,115...25,443,718
JBrowse link
G Cdk18 cyclin-dependent kinase 18 affects expression EXP Cocaine affects the expression of CDK18 mRNA CTD PMID:20187946 NCBI chr13:48,893,525...48,926,673
Ensembl chr13:48,893,412...48,927,483
JBrowse link
G Cdk4 cyclin-dependent kinase 4 affects expression ISO Cocaine affects the expression of CDK4 mRNA CTD PMID:18355967 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdk5 cyclin-dependent kinase 5 affects expression
increases expression
decreases expression
EXP Cocaine affects the expression of CDK5 mRNA; Cocaine affects the expression of CDK5 protein
Cocaine results in increased expression of CDK5 mRNA; Cocaine results in increased expression of CDK5 protein
Cocaine results in decreased expression of CDK5 protein
CTD PMID:11268215, PMID:12787079, PMID:16263094, PMID:17339080, PMID:17680995, PMID:20187946 NCBI chr 4:7,282,945...7,287,427
Ensembl chr 4:7,282,948...7,288,383
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions
increases expression
decreases expression
ISO
EXP
CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAP2K2 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK1 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of MAPK3 protein]; CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]
Cocaine results in increased expression of CDK5R1 mRNA; Cocaine results in increased expression of CDK5R1 protein
Cocaine results in decreased expression of CDK5R1 protein
CTD PMID:11268215, PMID:15665076, PMID:16263094 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Cocaine results in increased expression of CDKN1A mRNA CTD PMID:27899881 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 affects expression EXP Cocaine affects the expression of CEACAM3 mRNA CTD PMID:20187946 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cel carboxyl ester lipase increases expression EXP Cocaine results in increased expression of CEL mRNA CTD PMID:27899881 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions
increases hydrolysis
affects binding
ISO CES1 protein results in increased metabolism of [Cocaine co-treated with Ethanol]; Cocaine inhibits the reaction [CES1 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate]; Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of Heroin]
CES1 protein results in increased hydrolysis of Cocaine
Cocaine binds to CES1 protein
CTD PMID:8930175, PMID:9311626, PMID:12679808, PMID:12773168, PMID:25445008 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions
decreases expression
increases hydrolysis
ISO Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased chemical synthesis of Morphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of 6-O-monoacetylmorphine]; Cocaine inhibits the reaction [CES2 protein results in increased hydrolysis of Heroin]
Cocaine results in decreased expression of CES2 mRNA
CES2 protein results in increased hydrolysis of Cocaine
CTD PMID:8930175, PMID:9169443, PMID:12629581 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cfh complement factor H decreases expression EXP Cocaine results in decreased expression of CFH mRNA CTD PMID:17898221 NCBI chr13:56,979,155...57,080,540
Ensembl chr13:56,978,607...57,080,622
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator affects expression ISO Cocaine affects the expression of CFLAR mRNA CTD PMID:15681117 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chfr checkpoint with forkhead and ring finger domains affects expression EXP Cocaine affects the expression of CHFR mRNA CTD PMID:20187946 NCBI chr12:52,562,594...52,596,162
Ensembl chr12:52,562,597...52,596,076
JBrowse link
G Chn1 chimerin 1 affects expression EXP Cocaine affects the expression of CHN1 mRNA CTD PMID:20187946 NCBI chr 3:60,512,360...60,668,413
Ensembl chr 3:60,513,077...60,611,924
JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects expression EXP Cocaine affects the expression of CHRM4 mRNA CTD PMID:20187946 NCBI chr 3:80,833,272...80,841,165
Ensembl chr 3:80,833,272...80,841,006
JBrowse link
G Chrm5 cholinergic receptor, muscarinic 5 decreases response to substance EXP CHRM5 mutant form results in decreased susceptibility to Cocaine CTD PMID:20393457 NCBI chr 3:103,966,451...104,018,815
Ensembl chr 3:103,966,451...104,018,861
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit multiple interactions EXP Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:10336510 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit decreases response to substance ISO CHRNA5 gene polymorphism results in decreased susceptibility to Cocaine CTD PMID:18519132 NCBI chr 8:59,561,817...59,590,172
Ensembl chr 8:59,561,721...59,590,172
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions
increases response to substance
EXP
ISO
Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA3 protein binds to CHRNB2 protein]]; Cocaine inhibits the reaction [Nicotine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]
CHRNB2 protein results in increased susceptibility to Cocaine
CTD PMID:10336510, PMID:11282258 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit increases expression EXP Cocaine results in increased expression of CHRNE mRNA CTD PMID:27899881 NCBI chr10:57,238,960...57,246,750
Ensembl chr10:57,238,946...57,243,435
JBrowse link
G Chtf8 chromosome transmission fidelity factor 8 decreases expression EXP Cocaine results in decreased expression of CHTF8 mRNA CTD PMID:17898221 NCBI chr19:39,077,580...39,087,880
Ensembl chr19:39,077,580...39,087,880
JBrowse link
G Churc1 churchill domain containing 1 decreases expression ISO Cocaine results in decreased expression of CHURC1 mRNA CTD PMID:15009677, PMID:16710320 NCBI chr 6:99,817,439...99,831,574
Ensembl chr 6:99,817,431...99,831,576
JBrowse link
G Ciao1 cytosolic iron-sulfur assembly component 1 affects expression EXP Cocaine affects the expression of CIAO1 mRNA CTD PMID:20187946 NCBI chr 3:119,671,778...119,677,324
Ensembl chr 3:119,671,779...119,678,092
JBrowse link
G Cidea cell death-inducing DFFA-like effector a affects expression ISO Cocaine affects the expression of CIDEA mRNA CTD PMID:15681117 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Cideb cell death-inducing DFFA-like effector b affects expression ISO Cocaine affects the expression of CIDEB mRNA CTD PMID:15681117 NCBI chr15:34,439,844...34,444,244
Ensembl chr15:34,439,876...34,444,244
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 increases expression EXP Cocaine results in increased expression of CISD1 protein CTD PMID:25100957 NCBI chr20:18,493,538...18,506,923
Ensembl chr20:18,493,538...18,506,912
JBrowse link
G Cisd2 CDGSH iron sulfur domain 2 increases expression EXP Cocaine results in increased expression of CISD2 mRNA CTD PMID:17898221 NCBI chr 2:240,586,754...240,611,560
Ensembl chr 2:240,586,754...240,611,560
JBrowse link
G Cited4 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 decreases expression EXP Cocaine results in decreased expression of CITED4 mRNA CTD PMID:27899881 NCBI chr 5:139,597,731...139,598,622
Ensembl chr 5:139,597,731...139,598,622
JBrowse link
G Ckb creatine kinase B multiple interactions ISO Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Ckm creatine kinase, M-type multiple interactions ISO Cocaine results in increased secretion of [CKB protein binds to CKM protein] CTD PMID:12359538 NCBI chr 1:80,321,507...80,331,841
Ensembl chr 1:80,321,585...80,331,841
JBrowse link
G Ckmt1 creatine kinase, mitochondrial 1 affects expression EXP Cocaine affects the expression of CKMT1 mRNA CTD PMID:20187946 NCBI chr 3:113,318,559...113,324,459
Ensembl chr 3:113,318,563...113,324,461
JBrowse link
G Clcn7 chloride voltage-gated channel 7 affects expression EXP Cocaine affects the expression of CLCN7 mRNA CTD PMID:20187946 NCBI chr10:14,492,844...14,518,167
Ensembl chr10:14,492,844...14,516,894
JBrowse link
G Cldn11 claudin 11 decreases expression ISO Cocaine results in decreased expression of CLDN11 mRNA CTD PMID:18357522 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Clec4f C-type lectin domain family 4, member F affects expression EXP Cocaine affects the expression of CLEC4F mRNA CTD PMID:20187946 NCBI chr 4:115,322,300...115,332,021
Ensembl chr 4:115,322,291...115,332,052
JBrowse link
G Clic1 chloride intracellular channel 1 decreases expression ISO Cocaine results in decreased expression of CLIC1 mRNA CTD PMID:18000554 NCBI chr20:5,040,314...5,049,166
Ensembl chr20:5,040,337...5,049,166
JBrowse link
G Clip1 CAP-GLY domain containing linker protein 1 increases expression ISO Cocaine results in increased expression of CLIP1 mRNA CTD PMID:18000554 NCBI chr12:38,345,203...38,452,650
Ensembl chr12:38,345,456...38,452,652
JBrowse link
G Clk1 CDC-like kinase 1 increases expression
multiple interactions
ISO Cocaine results in increased expression of CLK1 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]
CTD PMID:18355967 NCBI chr 9:65,296,777...65,308,017
Ensembl chr 9:65,296,778...65,307,995
JBrowse link
G Clk4 CDC-like kinase 4 increases expression ISO Cocaine results in increased expression of CLK4 mRNA CTD PMID:20056891 NCBI chr10:36,715,565...36,733,473
Ensembl chr10:36,715,565...36,733,133
JBrowse link
G Clock clock circadian regulator increases expression ISO Cocaine results in increased expression of CLOCK mRNA CTD PMID:15994025 NCBI chr14:34,418,226...34,502,218
Ensembl chr14:34,446,616...34,502,218
JBrowse link
G Cltb clathrin, light chain B decreases expression ISO Cocaine results in decreased expression of CLTB mRNA CTD PMID:12629581, PMID:15009677 NCBI chr17:10,537,348...10,554,999
Ensembl chr17:10,537,365...10,554,989
JBrowse link
G Clybl citramalyl-CoA lyase increases expression EXP Cocaine results in increased expression of CLYBL protein CTD PMID:25100957 NCBI chr15:108,608,203...108,838,222
Ensembl chr15:108,608,204...108,838,235
JBrowse link
G Cnbd2 cyclic nucleotide binding domain containing 2 increases expression EXP Cocaine results in increased expression of CNBD2 mRNA CTD PMID:17898221 NCBI chr 3:152,382,245...152,448,105
Ensembl chr 3:152,402,520...152,465,228
JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 increases expression ISO Cocaine results in increased expression of CNKSR2 mRNA CTD PMID:15009677 NCBI chr  X:39,711,001...39,953,860
Ensembl chr  X:39,711,201...39,951,847
JBrowse link
G Cnr1 cannabinoid receptor 1 affects response to substance
increases activity
decreases response to substance
multiple interactions
ISO CNR1 gene polymorphism affects the susceptibility to Cocaine; CNR1 gene SNP affects the susceptibility to Cocaine; CNR1 polymorphism affects the susceptibility to Cocaine
Cocaine results in increased activity of CNR1 protein
CNR1 mutant form results in decreased susceptibility to Cocaine
CNR1 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of PPP1R1B protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:9106242, PMID:16314880, PMID:17596442, PMID:19052543, PMID:20554863 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression ISO Cocaine results in increased expression of CNR2 mRNA CTD PMID:18286196 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 increases expression ISO Cocaine results in increased expression of COBLL1 mRNA CTD PMID:27506785 NCBI chr 3:51,137,104...51,298,956
Ensembl chr 3:51,137,076...51,297,852
JBrowse link
G Coil coilin affects expression EXP Cocaine affects the expression of COIL mRNA CTD PMID:20187946 NCBI chr10:76,320,676...76,336,169
Ensembl chr10:76,320,041...76,341,418
JBrowse link
G Col15a1 collagen type XV alpha 1 chain affects expression EXP Cocaine affects the expression of COL15A1 mRNA CTD PMID:20187946 NCBI chr 5:62,840,360...62,950,240 JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP Cocaine results in increased expression of COL1A1 mRNA CTD PMID:9455993 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression EXP Cocaine results in increased expression of COL3A1 mRNA CTD PMID:9455993 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Coq6 coenzyme Q6 monooxygenase affects expression EXP Cocaine affects the expression of COQ6 mRNA CTD PMID:20187946 NCBI chr 6:108,076,393...108,087,782
Ensembl chr 6:108,076,306...108,087,696
JBrowse link
G Coro7 coronin 7 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA CTD PMID:18355967 NCBI chr10:11,090,200...11,144,289
Ensembl chr10:11,090,314...11,143,881
JBrowse link
G Cox20 cytochrome c oxidase assembly factor COX20 decreases expression EXP Cocaine results in decreased expression of COX20 mRNA CTD PMID:17898221 NCBI chr13:96,219,853...96,224,023
Ensembl chr13:96,219,853...96,224,023
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A affects expression EXP Cocaine affects the expression of COX5A mRNA CTD PMID:20187946 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 affects expression
increases expression
EXP Cocaine affects the expression of COX6A1 mRNA
Cocaine results in increased expression of COX6A1 protein
CTD PMID:20187946, PMID:25100957 NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C decreases expression ISO Cocaine results in decreased expression of COX6C mRNA CTD PMID:12629581 NCBI chr 7:74,723,177...74,735,650
Ensembl chr 7:74,723,179...74,735,650
JBrowse link
G Cox7b cytochrome c oxidase subunit 7B affects expression EXP Cocaine affects the expression of COX7B mRNA CTD PMID:20187946 NCBI chr  X:77,065,427...77,071,676
Ensembl chr  X:77,065,397...77,071,676
JBrowse link
G Cox8a cytochrome c oxidase subunit 8A affects expression EXP Cocaine affects the expression of COX8A mRNA CTD PMID:20187946 NCBI chr 1:222,466,575...222,468,896
Ensembl chr 1:222,466,575...222,468,896
JBrowse link
G Cplx1 complexin 1 affects expression EXP Cocaine affects the expression of CPLX1 mRNA CTD PMID:20187946 NCBI chr14:2,194,895...2,226,610
Ensembl chr14:2,194,933...2,226,598
JBrowse link
G Cpne8 copine 8 increases expression EXP Cocaine results in increased expression of CPNE8 mRNA CTD PMID:17898221 NCBI chr 7:131,623,180...131,798,236
Ensembl chr 7:131,623,181...131,798,236
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression
increases phosphorylation
multiple interactions
affects phosphorylation
increases expression
EXP
ISO
Cocaine affects the expression of CREB1 mRNA
Cocaine results in increased phosphorylation of CREB1 protein
CDK5R1 protein inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; Cocaine inhibits the reaction [CREB1 protein binds to BDNF promoter]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of CREB1 protein]; RPS6KA3 gene mutant form inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
Cocaine affects the phosphorylation of CREB1 protein
Betaxolol affects the reaction [Cocaine affects the phosphorylation of CREB1 protein]; Cocaine affects the reaction [CREB1 modified form binds to BDNF promoter]; Cocaine promotes the reaction [RPS6KA1 protein binds to CREB1 protein]; Cocaine results in increased phosphorylation of and results in increased activity of CREB1 protein; U 0126 inhibits the reaction [Cocaine results in increased phosphorylation of CREB1 protein]
CTD PMID:12595601, PMID:15470197, PMID:15665076, PMID:16219028, PMID:16339038, PMID:16710312, PMID:18596687, PMID:20187946, PMID:20810894, PMID:24358339 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crebbp CREB binding protein increases expression EXP Cocaine results in increased expression of CREBBP mRNA CTD PMID:17898221 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Crebrf CREB3 regulatory factor increases expression EXP Cocaine results in increased expression of CREBRF mRNA CTD PMID:17898221 NCBI chr10:16,693,846...16,753,162
Ensembl chr10:16,694,792...16,752,205
JBrowse link
G Crem cAMP responsive element modulator affects expression
increases expression
ISO
EXP
Cocaine affects the expression of CREM mRNA
Cocaine results in increased expression of CREM mRNA
CTD PMID:18355967, PMID:27899881 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Crh corticotropin releasing hormone multiple interactions
affects expression
EXP Betaxolol affects the reaction [Cocaine affects the expression of CRH mRNA]; Cocaine affects the reaction [CRH protein affects the secretion of Excitatory Amino Acid Agents]; SCH 23390 affects the reaction [Cocaine affects the expression of CRH mRNA]
Cocaine affects the expression of CRH mRNA; Cocaine affects the expression of CRH protein
CTD PMID:7796157, PMID:11597771, PMID:12782395, PMID:15930388, PMID:18596687 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Crhbp corticotropin releasing hormone binding protein increases expression EXP Cocaine results in increased expression of CRHBP mRNA CTD PMID:27899881 NCBI chr 2:25,141,471...25,153,334
Ensembl chr 2:25,141,471...25,153,334
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression EXP Cocaine results in increased expression of CRHR1 protein CTD PMID:17079348 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Crip2 cysteine-rich protein 2 affects expression EXP Cocaine affects the expression of CRIP2 mRNA CTD PMID:20187946 NCBI chr 6:137,953,545...137,958,491
Ensembl chr 6:137,953,545...137,958,490
JBrowse link
G Crispld1 cysteine-rich secretory protein LCCL domain containing 1 decreases expression EXP Cocaine results in decreased expression of CRISPLD1 mRNA CTD PMID:27899881 NCBI chr 5:663,750...711,033
Ensembl chr 5:670,754...711,033
JBrowse link
G Crp C-reactive protein increases expression ISO Cocaine results in increased expression of CRP protein CTD PMID:11988210 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Crtac1 cartilage acidic protein 1 affects expression EXP Cocaine affects the expression of CRTAC1 mRNA CTD PMID:20187946 NCBI chr 1:261,527,009...261,669,614
Ensembl chr 1:261,514,141...261,669,586
JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 multiple interactions EXP [[Cocaine results in increased expression of MIR212 mRNA] which results in increased activity of RAF1 protein] which results in increased expression of CRTC1 protein CTD PMID:20613834 NCBI chr16:20,740,746...20,798,145
Ensembl chr16:20,740,826...20,794,039
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Cocaine results in decreased expression of CRY1 mRNA CTD PMID:15994025 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Cry2 cryptochrome circadian regulator 2 decreases expression ISO Cocaine results in decreased expression of CRY2 mRNA CTD PMID:15994025 NCBI chr 3:81,314,151...81,344,143
Ensembl chr 3:81,314,149...81,344,110
JBrowse link
G Cryab crystallin, alpha B decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of CRYAB mRNA
Cocaine results in increased expression of CRYAB mRNA
CTD PMID:15009677, PMID:27899881 NCBI chr 8:55,178,543...55,182,546
Ensembl chr 8:55,178,289...55,182,545
JBrowse link
G Crybb2 crystallin, beta B2 decreases expression ISO Cocaine results in decreased expression of CRYBB2 mRNA CTD PMID:15009677 NCBI chr12:49,577,580...49,588,555
Ensembl chr12:49,578,633...49,588,555
JBrowse link
G Csad cysteine sulfinic acid decarboxylase affects expression
decreases expression
EXP Cocaine affects the expression of CSAD mRNA
Cocaine results in decreased expression of CSAD protein
CTD PMID:20187946, PMID:25100957 NCBI chr 7:143,781,520...143,810,880
Ensembl chr 7:143,781,702...143,793,970
JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha decreases expression EXP Cocaine results in decreased expression of CSF2RA mRNA CTD PMID:17898221 NCBI chr14:1,462,292...1,467,264
Ensembl chr14:1,462,358...1,467,264
JBrowse link
G Csn3 casein kappa affects expression EXP Cocaine affects the expression of CSN3 mRNA CTD PMID:20187946 NCBI chr14:21,803,738...21,810,291
Ensembl chr14:21,803,735...21,810,314
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression EXP Cocaine results in decreased expression of CSNK2A1 mRNA CTD PMID:12117546 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
JBrowse link
G Cspg5 chondroitin sulfate proteoglycan 5 affects expression EXP Cocaine affects the expression of CSPG5 mRNA; Cocaine affects the expression of CSPG5 protein CTD PMID:12358776 NCBI chr 8:118,333,695...118,348,040
Ensembl chr 8:118,333,706...118,347,582
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 decreases expression ISO Cocaine results in decreased expression of CSRP2 mRNA CTD PMID:18000554 NCBI chr 7:53,630,675...53,649,309
Ensembl chr 7:53,630,621...53,649,310
JBrowse link
G Ctdnep1 CTD nuclear envelope phosphatase 1 affects expression EXP Cocaine affects the expression of CTDNEP1 mRNA CTD PMID:20187946 NCBI chr10:56,590,822...56,600,235
Ensembl chr10:56,591,292...56,600,232
JBrowse link
G Ctnnb1 catenin beta 1 affects expression
multiple interactions
EXP Cocaine affects the expression of CTNNB1 mRNA
Cocaine deficiency promotes the reaction [SMARCA4 protein binds to CTNNB1 promoter]
CTD PMID:20187946, PMID:27422367 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 decreases expression ISO Cocaine results in decreased expression of CTNNBIP1 mRNA CTD PMID:18000554 NCBI chr 5:166,464,170...166,513,030
Ensembl chr 5:166,464,252...166,513,027
JBrowse link
G Ctnnd2 catenin delta 2 decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of CTNND2 mRNA
Cocaine results in increased expression of CTNND2 mRNA
CTD PMID:12629581, PMID:16076954 NCBI chr 2:83,227,247...84,094,315
Ensembl chr 2:83,393,282...84,094,315
JBrowse link
G Ctrl chymotrypsin-like affects expression
increases expression
EXP Cocaine affects the expression of CTRL mRNA
Cocaine results in increased expression of CTRL mRNA
CTD PMID:20187946, PMID:27899881 NCBI chr19:37,905,864...37,907,714
Ensembl chr19:37,905,864...37,907,714
JBrowse link
G Ctsb cathepsin B affects expression
multiple interactions
increases expression
ISO Cocaine affects the expression of CTSB mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]
CTD PMID:15681117, PMID:18355967 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D affects expression
increases expression
ISO
EXP
Cocaine affects the expression of CTSD mRNA
Cocaine results in increased expression of CTSD protein
CTD PMID:15681117, PMID:25100957 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cuedc1 CUE domain containing 1 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of CUEDC1 mRNA] CTD PMID:17988634 NCBI chr10:75,495,817...75,516,280
Ensembl chr10:75,495,817...75,516,304
JBrowse link
G Cul4b cullin 4B increases expression ISO Cocaine results in increased expression of CUL4B mRNA CTD PMID:15009677 NCBI chr  X:124,831,391...124,870,329
Ensembl chr  X:124,832,628...124,870,329
JBrowse link
G Cwf19l2 CWF19 like cell cycle control factor 2 increases expression EXP Cocaine results in increased expression of CWF19L2 mRNA CTD PMID:17898221 NCBI chr 6:18,970,616...19,037,176
Ensembl chr 6:18,970,564...19,055,924
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP Cocaine results in increased expression of CX3CL1 mRNA CTD PMID:16076954 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases secretion ISO Cocaine results in increased secretion of CXCL10 protein CTD PMID:10065903 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression EXP Cocaine results in decreased expression of CXCL9 mRNA CTD PMID:17898221 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Cocaine results in increased expression of CXCR4 protein CTD PMID:16204638 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cxxc5 CXXC finger protein 5 affects expression EXP Cocaine affects the expression of CXXC5 mRNA CTD PMID:20187946 NCBI chr18:28,626,386...28,656,916
Ensembl chr18:28,653,592...28,656,937
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression ISO Cocaine results in increased expression of CYBA protein CTD PMID:18952886 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression
increases response to substance
ISO Cocaine results in increased expression of CYBB protein
CYBB results in increased susceptibility to Cocaine
CTD PMID:18952886 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyc1 cytochrome c-1 decreases expression ISO Cocaine results in decreased expression of CYC1 mRNA CTD PMID:12629581 NCBI chr 7:117,409,576...117,411,953
Ensembl chr 7:117,409,576...117,411,953
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
affects expression
EXP
ISO
Minocycline inhibits the reaction [Cocaine results in increased secretion of CYCS protein]
Cocaine affects the expression of CYCS mRNA
CTD PMID:15681117, PMID:21424555 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cygb cytoglobin decreases expression EXP Cocaine results in decreased expression of CYGB protein CTD PMID:25100957 NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression EXP Cocaine results in decreased expression of CYP19A1 mRNA CTD PMID:27899881 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP1A1 protein] CTD PMID:11856816 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 affects expression EXP Cocaine affects the expression of CYP26A1 mRNA CTD PMID:20187946 NCBI chr 1:256,382,861...256,386,729
Ensembl chr 1:256,382,791...256,386,729
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 decreases response to substance EXP CYP26B1 protein results in decreased susceptibility to Cocaine CTD PMID:27899881 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases expression ISO Cocaine results in decreased expression of CYP2C8 mRNA; Cocaine results in decreased expression of CYP2C8 protein CTD PMID:16188404 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2j10 cytochrome P450, family 2, subfamily j, polypeptide 10 decreases expression EXP Cocaine results in decreased expression of CYP2J10 mRNA CTD PMID:27899881 NCBI chr 5:115,067,847...115,101,961
Ensembl chr 5:115,021,723...115,222,084
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression
multiple interactions
ISO Cocaine results in increased expression of CYP2J2 protein
Cimetidine inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]; Metyrapone inhibits the reaction [Cocaine results in increased expression of CYP2J2 protein]
CTD PMID:11856816 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression EXP Cocaine affects the expression of CYP3A23-3A1 mRNA CTD PMID:20187946 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp51 cytochrome P450, family 51 decreases expression ISO Cocaine results in decreased expression of CYP51 mRNA CTD PMID:12629581 NCBI chr 4:27,175,564...27,194,018
Ensembl chr 4:27,175,243...27,194,018
JBrowse link
G Cyss cystatin S affects expression EXP Cocaine affects the expression of CYSS mRNA CTD PMID:20187946 NCBI chr 3:144,427,430...144,431,768
Ensembl chr 3:144,427,207...144,431,806
JBrowse link
G Dab2ip DAB2 interacting protein decreases expression EXP Cocaine results in decreased expression of DAB2IP mRNA CTD PMID:17898221 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Dazap1 DAZ associated protein 1 affects expression EXP Cocaine affects the expression of DAZAP1 mRNA CTD PMID:20187946 NCBI chr 7:12,289,895...12,315,897
Ensembl chr 7:12,290,402...12,311,149
JBrowse link
G Dbh dopamine beta-hydroxylase increases response to substance
decreases response to substance
ISO DBH gene polymorphism results in increased susceptibility to Cocaine
DBH gene mutant form results in decreased susceptibility to Cocaine
CTD PMID:10673769, PMID:12555232, PMID:18083142 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Dbn1 drebrin 1 multiple interactions EXP Cocaine deficiency promotes the reaction [SMARCA4 protein binds to DBN1 promoter] CTD PMID:27422367 NCBI chr17:9,679,511...9,693,878
Ensembl chr17:9,679,628...9,693,820
JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 affects expression EXP Cocaine affects the expression of DCAF8 mRNA CTD PMID:20187946 NCBI chr13:90,532,153...90,587,542
Ensembl chr13:90,532,326...90,591,796
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 affects expression
increases expression
ISO
EXP
Cocaine affects the expression of DDIT3 mRNA
Cocaine results in increased expression of DDIT3 mRNA
CTD PMID:15681117, PMID:20187946, PMID:23644055 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression EXP Cocaine results in decreased expression of DDR2 mRNA CTD PMID:17898221 NCBI chr13:88,311,639...88,436,561
Ensembl chr13:88,317,145...88,436,789
JBrowse link
G Ddx41 DEAD-box helicase 41 decreases expression ISO Cocaine results in decreased expression of DDX41 mRNA CTD PMID:18000554 NCBI chr17:9,631,925...9,637,317
Ensembl chr17:9,631,925...9,637,316
JBrowse link
G Ddx50 DExD-box helicase 50 affects expression EXP Cocaine affects the expression of DDX50 mRNA CTD PMID:20187946 NCBI chr20:32,239,736...32,269,522
Ensembl chr20:32,239,748...32,269,145
JBrowse link
G Ddx6 DEAD-box helicase 6 increases expression EXP Cocaine results in increased expression of DDX6 mRNA CTD PMID:17898221 NCBI chr 8:48,924,768...48,961,394
Ensembl chr 8:48,925,604...48,958,026
JBrowse link
G Deaf1 DEAF1 transcription factor decreases expression ISO Cocaine results in decreased expression of DEAF1 mRNA CTD PMID:15009677, PMID:16710320 NCBI chr 1:214,283,787...214,317,466
Ensembl chr 1:214,283,790...214,317,466
JBrowse link
G Dhh desert hedgehog signaling molecule affects expression EXP Cocaine affects the expression of DHH mRNA CTD PMID:20187946 NCBI chr 7:140,575,288...140,580,783
Ensembl chr 7:140,575,288...140,580,783
JBrowse link
G Dhx30 DExH-box helicase 30 affects expression EXP Cocaine affects the expression of DHX30 mRNA CTD PMID:20187946 NCBI chr 8:118,160,315...118,194,674
Ensembl chr 8:118,160,299...118,187,791
JBrowse link
G Dipk1b divergent protein kinase domain 1B affects expression EXP Cocaine affects the expression of DIPK1B mRNA CTD PMID:20187946 NCBI chr 3:4,083,797...4,091,550
Ensembl chr 3:4,083,864...4,092,289
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression EXP Cocaine results in increased expression of DLG2 protein CTD PMID:25100957 NCBI chr 1:154,916,274...157,274,077
Ensembl chr 1:156,552,328...157,269,747
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 affects expression
increases expression
multiple interactions
decreases response to substance
decreases expression
EXP
ISO
Cocaine affects the expression of DLG4 mRNA; Cocaine affects the expression of DLG4 protein
Cocaine results in increased expression of DLG4 protein
ILK mutant form inhibits the reaction [Cocaine results in increased expression of DLG4 protein]
DLG4 protein results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of DLG4 mRNA
CTD PMID:14980210, PMID:19629758, PMID:20187946, PMID:20534846, PMID:20600170 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
JBrowse link
G Dlk2 delta like non-canonical Notch ligand 2 decreases expression
multiple interactions
ISO Cocaine results in decreased expression of DLK2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]
CTD PMID:18355967 NCBI chr 9:17,061,187...17,065,600
Ensembl chr 9:17,061,190...17,065,600
JBrowse link
G Dnah8 dynein, axonemal, heavy chain 8 affects response to substance ISO DNAH8 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr20:9,301,317...9,560,805
Ensembl chr20:9,313,271...9,560,682
JBrowse link
G Dnm1 dynamin 1 affects expression EXP Cocaine affects the expression of DNM1 mRNA CTD PMID:20187946 NCBI chr 3:11,338,081...11,382,043
Ensembl chr 3:11,338,083...11,382,043
JBrowse link
G Dnm1l dynamin 1-like multiple interactions
increases phosphorylation
EXP
ISO
[Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to DNM1L promoter]
Cocaine results in increased phosphorylation of DNM1L protein
CTD PMID:30158054, PMID:31494168 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dnm2 dynamin 2 affects expression EXP Cocaine affects the expression of DNM2 mRNA CTD PMID:20187946 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524
JBrowse link
G Dnm3 dynamin 3 affects expression EXP Cocaine affects the expression of DNM3 mRNA CTD PMID:20187946 NCBI chr13:79,906,711...80,379,967
Ensembl chr13:79,910,382...80,379,929
JBrowse link
G Dnmbp dynamin binding protein decreases expression EXP Cocaine results in decreased expression of DNMBP mRNA CTD PMID:17898221 NCBI chr 1:263,625,503...263,718,784
Ensembl chr 1:263,625,501...263,718,745
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression
multiple interactions
ISO Cocaine results in decreased expression of DNMT3B mRNA; Cocaine results in decreased expression of DNMT3B protein
Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B mRNA]; Methionine inhibits the reaction [Cocaine results in decreased expression of DNMT3B protein]
CTD PMID:22438930 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dnph1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 decreases expression ISO Cocaine results in decreased expression of DNPH1 mRNA CTD PMID:15009677, PMID:16710320 NCBI chr 9:16,845,764...16,848,514
Ensembl chr 9:16,845,525...16,848,503
JBrowse link
G Dpf2 double PHD fingers 2 increases expression ISO Cocaine results in increased expression of DPF2 mRNA CTD PMID:18000554 NCBI chr 1:221,253,764...221,269,043
Ensembl chr 1:221,253,747...221,269,042
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions EXP [Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of DPYSL2 protein CTD PMID:19457111 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 affects expression EXP Cocaine affects the expression of DPYSL3 mRNA CTD PMID:20187946 NCBI chr18:37,716,371...37,819,347
Ensembl chr18:37,716,143...37,819,097
JBrowse link
G Drd1 dopamine receptor D1 multiple interactions
decreases expression
affects response to substance
affects expression
increases response to substance
decreases response to substance
ISO
EXP
1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; [Cocaine binds to SIGMAR1 protein] affects the folding of [SIGMAR1 protein binds to DRD1 protein]; Cocaine affects the localization of [DRD1 protein binds to SIGMAR1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Cocaine promotes the reaction [DRD1 protein binds to SIGMAR1 protein]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]
Cocaine results in decreased expression of DRD1 protein
DRD1 protein affects the susceptibility to Cocaine
Cocaine affects the expression of DRD1 protein
DRD1 results in increased susceptibility to Cocaine
DRD1 gene mutant form results in decreased susceptibility to Cocaine
Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of NEO1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of PDYN protein]; Cocaine promotes the reaction [DRD1 protein results in increased expression of SYT7 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD1 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; DRD1 mutant form inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein]
[anhydroecgonine methyl ester co-treated with Cocaine] results in decreased expression of DRD1 protein; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine affects the reaction [SCH 23390 binds to DRD1 protein]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]
CTD PMID:2213551, PMID:8001143, PMID:11421588, PMID:11602327, PMID:15049517, PMID:15056714, PMID:16674926, PMID:17161392, PMID:20435100, PMID:20456009, PMID:20956312, PMID:27129946 NCBI chr17:11,099,736...11,104,352
Ensembl chr17:11,101,306...11,103,541
JBrowse link
G Drd2 dopamine receptor D2 decreases expression
affects response to substance
increases activity
increases expression
multiple interactions
affects expression
decreases response to substance
increases response to substance
ISO
EXP
Cocaine results in decreased expression of DRD2 mRNA; Cocaine results in decreased expression of DRD2 protein
DRD2 protein affects the susceptibility to Cocaine
Cocaine results in increased activity of DRD2 protein
Cocaine results in increased expression of DRD2 mRNA; Cocaine results in increased expression of DRD2 protein
Cocaine affects the reaction [Spiperone binds to DRD2 protein]; Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]; Methadone affects the reaction [Cocaine affects the expression of DRD2 mRNA]; Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]]
Cocaine affects the expression of DRD2; Cocaine affects the expression of DRD2 mRNA; Cocaine affects the expression of DRD2 protein
DRD2 protein results in decreased susceptibility to Cocaine
PDYN protein affects the reaction [Cocaine affects the expression of DRD2 protein]
DRD2 results in increased susceptibility to Cocaine
DRD2 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the reaction [Raclopride binds to DRD2]
CTD PMID:2213551, PMID:9892293, PMID:11126397, PMID:11602327, PMID:11790512, PMID:11923462, PMID:12892653, PMID:15010698, PMID:15042275, PMID:15049517, PMID:17161392, PMID:17532787, PMID:17544385, PMID:17671965, PMID:18000554, PMID:18305460, PMID:18990547, PMID:19046384, PMID:19723785, PMID:20435100, PMID:20729865 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 decreases expression
decreases response to substance
increases expression
increases activity
affects expression
affects activity
multiple interactions
affects response to substance
ISO
EXP
Cocaine results in decreased expression of DRD3 protein
DRD3 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of DRD3 mRNA
Cocaine results in increased activity of DRD3 protein
Cocaine affects the expression of DRD3 protein
Cocaine affects the activity of DRD3 protein
DRD3 protein results in decreased susceptibility to Cocaine
7-hydroxy-2-N,N-dipropylaminotetralin inhibits the reaction [Cocaine affects the activity of DRD3 protein]; Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]; KN 93 inhibits the reaction [Cocaine promotes the reaction [DRD3 protein binds to CAMK2A protein]]
DRD3 affects the susceptibility to Cocaine
[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine; [3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol co-treated with Cocaine] affects the localization of DRD3 protein; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of NEO1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of PDYN protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of SYT7 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]; Cocaine promotes the reaction [DRD3 protein results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]; DRD3 protein affects the reaction [Cocaine results in increased expression of NTS mRNA]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of PDYN protein]; SB 277011 inhibits the reaction [[3,4,4a,10b-tetrahydro-4-propyl-2H,5H-(1)benzopyrano(4,3-b)-1,4-oxazin-9-ol binds to and results in increased activity of DRD3 protein] which results in decreased susceptibility to Cocaine]
CTD PMID:10523822, PMID:10943692, PMID:11120399, PMID:12099907, PMID:15056714, PMID:15100700, PMID:16026479, PMID:18566292, PMID:19046384, PMID:19217379, PMID:19723785, PMID:20435100, PMID:20456009 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Drd4 dopamine receptor D4 increases response to substance
affects expression
ISO
EXP
DRD4 polymorphism results in increased susceptibility to Cocaine
Cocaine affects the expression of DRD4 mRNA
CTD PMID:17671965, PMID:20187946 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Drd5 dopamine receptor D5 affects expression EXP Cocaine affects the expression of DRD5 mRNA CTD PMID:20187946 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Drp2 dystrophin related protein 2 affects expression ISO Cocaine affects the expression of DRP2 protein CTD PMID:19393250 NCBI chr  X:105,239,623...105,290,233
Ensembl chr  X:105,239,620...105,289,808
JBrowse link
G Dsp desmoplakin increases expression ISO Cocaine results in increased expression of DSP protein CTD PMID:17075605 NCBI chr17:27,286,811...27,334,453
Ensembl chr17:27,286,796...27,334,379
JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression
increases phosphorylation
EXP Cocaine affects the expression of DUSP1 mRNA
Cocaine results in increased phosphorylation of DUSP1 protein
CTD PMID:18822274, PMID:20187946 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp5 dual specificity phosphatase 5 affects expression
increases expression
EXP Cocaine affects the expression of CPG21 mRNA
Cocaine results in increased expression of DUSP5 mRNA
CTD PMID:20187946, PMID:27899881 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dusp8 dual specificity phosphatase 8 multiple interactions
increases expression
EXP 5,7-Dihydroxytryptamine inhibits the reaction [Cocaine results in increased expression of DUSP8 mRNA] CTD PMID:9813294 NCBI chr 1:215,030,429...215,043,111
Ensembl chr 1:215,030,429...215,033,460
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 affects expression EXP Cocaine affects the expression of DVL1 mRNA CTD PMID:20187946 NCBI chr 5:173,295,948...173,308,014
Ensembl chr 5:173,296,270...173,307,945
JBrowse link
G Dync1i1 dynein cytoplasmic 1 intermediate chain 1 decreases expression ISO Cocaine results in decreased expression of DYNC1I1 mRNA CTD PMID:12629581 NCBI chr 4:30,807,755...31,121,097
Ensembl chr 4:30,807,879...31,121,090
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 increases expression EXP Cocaine results in increased expression of DYNC1LI2 protein CTD PMID:25100957 NCBI chr19:740,007...762,897
Ensembl chr19:740,028...762,897
JBrowse link
G Dynll1 dynein light chain LC8-type 1 affects expression EXP Cocaine affects the expression of DYNLL1 mRNA CTD PMID:20187946 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Cocaine affects the expression of PECI mRNA CTD PMID:20187946 NCBI chr17:30,556,926...30,573,324
Ensembl chr17:30,556,884...30,639,040
JBrowse link
G Edn1 endothelin 1 increases expression EXP
ISO
Cocaine results in increased expression of EDN1 protein CTD PMID:9714087, PMID:11948058, PMID:17420087, PMID:18813882 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A increases expression ISO
EXP
Cocaine results in increased expression of EDNRA protein CTD PMID:17420087, PMID:18813882 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B affects expression EXP Cocaine affects the expression of EDNRB mRNA CTD PMID:20187946 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 affects expression EXP Cocaine affects the expression of EEF1A1 mRNA CTD PMID:20187946 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 affects expression EXP Cocaine affects the expression of EEF1A2 mRNA CTD PMID:20187946 NCBI chr 3:176,657,104...176,666,282
Ensembl chr 3:176,657,107...176,666,282
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma decreases expression ISO Cocaine results in decreased expression of EEF1G mRNA CTD PMID:15009677 NCBI chr 1:225,163,391...225,173,997
Ensembl chr 1:225,163,391...225,173,995
JBrowse link
G Efcab3 EF-hand calcium binding domain 3 affects expression
decreases expression
EXP Cocaine affects the expression of EFCAB3 mRNA
Cocaine results in decreased expression of EFCAB3 mRNA
CTD PMID:17898221, PMID:20187946 NCBI chr10:93,304,559...93,332,849
Ensembl chr10:93,305,969...93,332,702
JBrowse link
G Efna1 ephrin A1 affects expression EXP Cocaine affects the expression of EFNA1 mRNA CTD PMID:15691709 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Efna2 ephrin A2 affects expression EXP Cocaine affects the expression of EFNA2 mRNA CTD PMID:15691709 NCBI chr 7:12,382,636...12,393,266
Ensembl chr 7:12,382,636...12,393,266
JBrowse link
G Efna3 ephrin A3 affects expression EXP Cocaine affects the expression of EFNA3 mRNA CTD PMID:15691709 NCBI chr 2:188,636,304...188,645,302
Ensembl chr 2:188,637,852...188,645,196
JBrowse link
G Efna4 ephrin A4 affects expression EXP Cocaine affects the expression of EFNA4 mRNA CTD PMID:15691709 NCBI chr 2:188,655,920...188,660,179
Ensembl chr 2:188,655,912...188,660,179
JBrowse link
G Efna5 ephrin A5 increases expression EXP Cocaine results in increased expression of EFNA5 mRNA CTD PMID:15691709 NCBI chr 9:110,054,002...110,329,878
Ensembl chr 9:110,057,155...110,225,486
JBrowse link
G Efnb1 ephrin B1 increases expression EXP Cocaine results in increased expression of EFNB1 mRNA CTD PMID:15691709, PMID:17898221 NCBI chr  X:68,891,227...68,904,034
Ensembl chr  X:68,891,227...68,904,038
JBrowse link
G Efnb2 ephrin B2 increases expression EXP Cocaine results in increased expression of EFNB2 mRNA CTD PMID:15691709 NCBI chr16:86,631,151...86,672,050
Ensembl chr16:86,631,064...86,675,049
JBrowse link
G Efnb3 ephrin B3 increases expression EXP Cocaine results in increased expression of EFNB3 mRNA CTD PMID:15691709 NCBI chr10:56,161,431...56,168,819
Ensembl chr10:56,161,432...56,167,426
JBrowse link
G Eftud2 elongation factor Tu GTP binding domain containing 2 affects expression EXP Cocaine affects the expression of EFTUD2 mRNA CTD PMID:20187946 NCBI chr10:90,932,071...90,983,971
Ensembl chr10:90,932,075...90,983,928
JBrowse link
G Egfr epidermal growth factor receptor decreases expression ISO Cocaine results in decreased expression of EGFR mRNA CTD PMID:18000554 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 affects expression
increases expression
multiple interactions
increases response to substance
ISO
EXP
Cocaine affects the expression of EGR1 mRNA
Cocaine results in increased expression of EGR1 protein
NPPC protein inhibits the reaction [Cocaine results in increased expression of EGR1 mRNA]
Cocaine results in increased expression of EGR1 mRNA; Cocaine results in increased expression of EGR1 protein
EGR1 results in increased susceptibility to Cocaine
[Cocaine co-treated with Caffeine] results in increased expression of EGR1 mRNA; Cocaine promotes the reaction [Caffeine results in increased expression of EGR1 mRNA]
CTD PMID:1347779, PMID:7905595, PMID:9890435, PMID:10971643, PMID:11860464, PMID:16339038, PMID:16459018, PMID:16738229, PMID:17851536, PMID:18311559, PMID:18355967, PMID:20187946 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 increases expression
affects expression
ISO
EXP
Cocaine results in increased expression of EGR2 mRNA
Cocaine affects the expression of EGR2 mRNA
CTD PMID:20056891, PMID:20187946, PMID:27899881 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Egr3 early growth response 3 affects expression
multiple interactions
increases expression
EXP Cocaine affects the expression of EGR3 mRNA
[Cocaine co-treated with Cocaine deficiency] promotes the reaction [RUNX2 protein binds to EGR3 promoter]
Cocaine results in increased expression of EGR3 mRNA
CTD PMID:16459018, PMID:20187946, PMID:30158054 NCBI chr15:51,756,683...51,762,080
Ensembl chr15:51,756,736...51,760,722
JBrowse link
G Egr4 early growth response 4 increases expression EXP Cocaine results in increased expression of EGR4 mRNA CTD PMID:27899881 NCBI chr 4:117,293,620...117,296,082
Ensembl chr 4:117,293,620...117,296,082
JBrowse link
G Ehd2 EH-domain containing 2 decreases expression EXP Cocaine results in decreased expression of EHD2 mRNA CTD PMID:17898221 NCBI chr 1:77,847,599...77,865,870
Ensembl chr 1:77,847,600...77,865,870
JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 decreases expression ISO Cocaine results in decreased expression of EHMT1 mRNA CTD PMID:20056891 NCBI chr 3:1,966,974...2,123,858
Ensembl chr 3:1,960,957...2,123,820
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 multiple interactions
decreases response to substance
decreases expression
ISO Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ATM mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TGFBR1 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of TNFRSF25 mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of USP9X mRNA]; EHMT2 inhibits the reaction [Cocaine results in increased expression of WNK3 mRNA]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]
EHMT2 results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of EHMT2 mRNA; Cocaine results in decreased expression of EHMT2 protein
CTD PMID:20056891 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
JBrowse link
G Eif1a eukaryotic translation initiation factor 1A increases expression EXP Cocaine results in increased expression of EIF1A mRNA; Cocaine results in increased expression of EIF1AY mRNA CTD PMID:17898221 NCBI chr18:40,586,315...40,598,661
Ensembl chr18:40,586,315...40,597,671
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions
EXP Cocaine results in increased expression of EIF2AK3 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein]
CTD PMID:17303341 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP Cocaine results in increased phosphorylation of EIF2S1 CTD PMID:18593214 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A increases expression EXP Cocaine results in increased expression of EIF3A mRNA CTD PMID:17898221 NCBI chr 1:282,139,809...282,170,017
Ensembl chr 1:282,139,823...282,170,017
JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B affects expression EXP Cocaine affects the expression of EIF3B mRNA CTD PMID:20187946 NCBI chr12:16,285,730...16,310,190
Ensembl chr12:16,285,733...16,310,190
JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C increases expression EXP Cocaine results in increased expression of EIF3C mRNA CTD PMID:17898221 NCBI chr 1:197,964,406...197,982,917
Ensembl chr 1:197,964,407...197,982,601
JBrowse link
G Eif3e eukaryotic translation initiation factor 3 subunit E affects expression EXP Cocaine affects the expression of EIF3E mRNA CTD PMID:20187946 NCBI chr 7:82,997,694...83,037,231 JBrowse link
G Eif4b eukaryotic translation initiation factor 4B multiple interactions
increases expression
ISO FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA] CTD PMID:18355967 NCBI chr 7:143,679,656...143,701,452
Ensembl chr 7:143,679,617...143,701,452
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression
affects expression
increases expression
ISO
EXP
Cocaine results in decreased expression of EIF5A mRNA
Cocaine affects the expression of EIF5A mRNA
Cocaine results in increased expression of EIF5A mRNA
CTD PMID:15009677, PMID:16710320, PMID:20187946 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases expression EXP Cocaine results in increased expression of EIF5B mRNA CTD PMID:17898221 NCBI chr 9:44,658,724...44,713,518
Ensembl chr 9:44,681,494...44,713,199
JBrowse link
G Eif5b-ps1 eukaryotic translation initiation factor 5B, pseudogene 1 increases expression EXP Cocaine results in increased expression of EIF5B-PS1 mRNA CTD PMID:17898221 NCBI chr19:38,340,738...38,344,845 JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO [Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein]] which results in decreased activity of ELANE protein; Cocaine affects the reaction [Antibodies, Antineutrophil Cytoplasmic binds to ELANE protein] CTD PMID:18438818 NCBI chr 7:12,638,320...12,640,168
Ensembl chr 7:12,638,322...12,640,232
JBrowse link
G Elmo1 engulfment and cell motility 1 multiple interactions
increases expression
ISO EHMT2 inhibits the reaction [Cocaine results in increased expression of ELMO1 mRNA] CTD PMID:20056891 NCBI chr17:46,352,102...46,888,788
Ensembl chr17:46,353,330...46,794,845
JBrowse link
G Emc9 ER membrane protein complex subunit 9 affects expression EXP Cocaine affects the expression of EMC9 mRNA CTD PMID:20187946 NCBI chr15:34,258,940...34,263,156
Ensembl chr15:34,256,374...34,263,224
JBrowse link
G Enah ENAH, actin regulator increases expression EXP Cocaine results in increased expression of ENAH mRNA CTD PMID:17898221 NCBI chr13:100,297,421...100,415,335
Ensembl chr13:100,300,054...100,414,226
JBrowse link
G Enc1 ectodermal-neural cortex 1 increases expression EXP Cocaine results in increased expression of ENC1 mRNA CTD PMID:17898221 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Enho energy homeostasis associated decreases expression ISO Cocaine results in decreased expression of ENHO mRNA CTD PMID:16710320 NCBI chr 5:58,018,039...58,019,836
Ensembl chr 5:58,018,039...58,019,836
JBrowse link
G Eno2 enolase 2 decreases expression
increases expression
ISO Cocaine results in decreased expression of ENO2 mRNA
Cocaine results in increased expression of ENO2 protein
CTD PMID:12629581, PMID:17075605 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Enpp5 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 increases expression ISO Cocaine results in increased expression of ENPP5 mRNA CTD PMID:15009677 NCBI chr 9:19,469,276...19,476,684
Ensembl chr 9:19,469,706...19,476,646
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 decreases expression EXP Cocaine results in decreased expression of ENTPD2 protein CTD PMID:25100957 NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445
JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA CTD PMID:18355967 NCBI chr 8:129,201,000...129,232,436
Ensembl chr 8:129,201,669...129,232,677
JBrowse link
G Epha1 Eph receptor A1 affects expression EXP Cocaine affects the expression of EPHA1 mRNA CTD PMID:15691709 NCBI chr 4:71,749,100...71,763,681
Ensembl chr 4:71,749,242...71,763,679
JBrowse link
G Epha2 Eph receptor A2 affects expression EXP Cocaine affects the expression of EPHA2 mRNA CTD PMID:15691709 NCBI chr 5:159,845,773...159,874,203
Ensembl chr 5:159,845,774...159,874,206
JBrowse link
G Epha3 Eph receptor A3 affects expression EXP Cocaine affects the expression of EPHA3 mRNA CTD PMID:15691709 NCBI chr11:421,253...783,037
Ensembl chr11:421,135...782,954
JBrowse link
G Epha4 Eph receptor A4 affects expression
increases expression
EXP Cocaine affects the expression of EPHA4 mRNA
Cocaine results in increased expression of EPHA4 mRNA
CTD PMID:15691709, PMID:17898221 NCBI chr 9:83,111,222...83,253,486
Ensembl chr 9:83,111,222...83,253,458
JBrowse link
G Epha5 EPH receptor A5 affects expression EXP Cocaine affects the expression of EPHA5 mRNA CTD PMID:15691709 NCBI chr14:25,589,312...25,958,258
Ensembl chr14:25,589,762...25,958,227
JBrowse link
G Epha7 Eph receptor A7 affects expression EXP Cocaine affects the expression of EPHA7 mRNA CTD PMID:15691709 NCBI chr 5:43,602,744...43,761,198
Ensembl chr 5:43,603,043...43,757,549
JBrowse link
G Epha8 Eph receptor A8 affects expression EXP Cocaine affects the expression of EPHA8 mRNA CTD PMID:15691709 NCBI chr 5:155,293,731...155,321,016
Ensembl chr 5:155,295,314...155,316,495
JBrowse link
G Ephb1 Eph receptor B1 increases expression ISO
EXP
Cocaine results in increased expression of EPHB1 protein
Cocaine results in increased expression of EPHB1 mRNA
CTD PMID:11146119, PMID:15691709 NCBI chr 8:110,376,954...110,813,193
Ensembl chr 8:110,376,954...110,813,000
JBrowse link
G Ephb2 Eph receptor B2 increases expression EXP Cocaine results in increased expression of EPHB2 mRNA CTD PMID:15691709 NCBI chr 5:155,024,478...155,143,539
Ensembl chr 5:155,022,493...155,204,456
JBrowse link
G Ephb3 Eph receptor B3 affects expression EXP Cocaine affects the expression of EPHB3 mRNA CTD PMID:15691709 NCBI chr11:83,527,960...83,546,742
Ensembl chr11:83,527,962...83,546,674
JBrowse link
G Ephb4 EPH receptor B4 decreases expression
affects expression
ISO
EXP
Cocaine results in decreased expression of EPHB4 mRNA
Cocaine affects the expression of EPHB4 mRNA
CTD PMID:15691709, PMID:18000554 NCBI chr12:22,393,338...22,418,332
Ensembl chr12:22,393,330...22,417,980
JBrowse link
G Ephb6 Eph receptor B6 affects expression EXP Cocaine affects the expression of EPHB6 mRNA CTD PMID:15691709 NCBI chr 4:70,903,253...70,918,514
Ensembl chr 4:70,903,253...70,918,514
JBrowse link
G Erbin erbb2 interacting protein multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of ERBIN mRNA] CTD PMID:17988634 NCBI chr 2:33,880,860...33,952,806
Ensembl chr 2:33,881,024...33,920,837
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression
EXP 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of ERN1 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Ess2 ess-2 splicing factor homolog decreases expression EXP Cocaine results in decreased expression of ESS2 mRNA CTD PMID:17898221 NCBI chr11:87,224,371...87,234,329
Ensembl chr11:87,224,421...87,233,326
JBrowse link
G Etf1 eukaryotic translation termination factor 1 affects expression EXP Cocaine affects the expression of ETF1 mRNA CTD PMID:20187946 NCBI chr18:27,698,693...27,725,694
Ensembl chr18:27,698,695...27,725,694
JBrowse link
G Etfa electron transfer flavoprotein subunit alpha affects expression EXP Cocaine affects the expression of ETFA mRNA CTD PMID:20187946 NCBI chr 8:60,028,786...60,086,352
Ensembl chr 8:60,028,789...60,086,403
JBrowse link
G Exoc2 exocyst complex component 2 increases expression EXP Cocaine results in increased expression of EXOC2 protein CTD PMID:25100957 NCBI chr17:34,665,810...34,842,266
Ensembl chr17:34,665,872...34,842,266
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 increases expression ISO Cocaine results in increased expression of EYA1 mRNA CTD PMID:15009677 NCBI chr 5:4,275,728...4,495,525
Ensembl chr 5:4,373,626...4,513,142
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 affects expression EXP Cocaine affects the expression of EYA2 mRNA CTD PMID:20187946 NCBI chr 3:162,285,275...162,470,642
Ensembl chr 3:162,346,490...162,470,065
JBrowse link
G Ezr ezrin decreases expression ISO Cocaine results in decreased expression of EZR mRNA CTD PMID:20948987 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G Fadd Fas associated via death domain affects expression
multiple interactions
decreases expression
EXP Cocaine affects the expression of FADD mRNA
Raclopride affects the reaction [Cocaine affects the expression of FADD protein]
Cocaine results in decreased expression of FADD protein modified form
CTD PMID:18580876 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fahd1 fumarylacetoacetate hydrolase domain containing 1 increases expression EXP Cocaine results in increased expression of FAHD1 protein CTD PMID:25100957 NCBI chr10:14,214,518...14,215,957
Ensembl chr10:14,214,519...14,215,957
JBrowse link
G Faim Fas apoptotic inhibitory molecule affects expression ISO Cocaine affects the expression of FAIM mRNA CTD PMID:15681117 NCBI chr 8:107,225,119...107,247,228
Ensembl chr 8:107,225,212...107,241,224
Ensembl chr 8:107,225,212...107,241,224
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression EXP Cocaine results in increased expression of FAIM2 mRNA CTD PMID:16076954 NCBI chr 7:141,158,769...141,185,781
Ensembl chr 7:141,157,963...141,185,710
JBrowse link
G Fam155a family with sequence similarity 155, member A increases expression EXP Cocaine results in increased expression of FAM155A mRNA CTD PMID:17898221 NCBI chr16:85,528,126...86,053,447 JBrowse link
G Fam184b family with sequence similarity 184, member B decreases expression EXP Cocaine results in decreased expression of FAM184B mRNA CTD PMID:27899881 NCBI chr14:69,970,034...70,086,018
Ensembl chr14:70,015,754...70,086,143
JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase affects expression EXP Cocaine affects the expression of FAM20C mRNA CTD PMID:20187946 NCBI chr12:17,913,771...17,972,733
Ensembl chr12:17,913,767...17,972,737
JBrowse link
G Fam78b family with sequence similarity 78, member B decreases expression EXP Cocaine results in decreased expression of FAM78B mRNA CTD PMID:17898221 NCBI chr13:85,110,536...85,233,243
Ensembl chr13:85,110,098...85,231,155
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Cocaine results in increased expression of FAS mRNA CTD PMID:16710320 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fbxl3 F-box and leucine-rich repeat protein 3 increases expression EXP Cocaine results in increased expression of FBXL3 mRNA CTD PMID:17898221 NCBI chr15:93,647,307...93,667,395
Ensembl chr15:93,647,310...93,667,395
JBrowse link
G Fbxo46 F-box protein 46 affects expression EXP Cocaine affects the expression of FBXO46 mRNA CTD PMID:20187946 NCBI chr 1:80,028,873...80,045,666
Ensembl chr 1:80,028,928...80,045,341
JBrowse link
G Fcgr2b Fc fragment of IgG receptor IIb decreases expression EXP Cocaine results in decreased expression of FCGR2B mRNA CTD PMID:27899881 NCBI chr13:89,329,298...89,343,916
Ensembl chr13:89,327,794...89,433,815
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Cocaine results in increased expression of FDFT1 mRNA CTD PMID:17205118 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fev FEV transcription factor, ETS family member decreases expression EXP Cocaine results in decreased expression of FEV mRNA CTD PMID:17898221 NCBI chr 9:82,142,981...82,146,855
Ensembl chr 9:82,142,981...82,146,874
JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 increases expression EXP Cocaine results in increased expression of FGD5 mRNA CTD PMID:17898221 NCBI chr 4:123,865,557...123,962,904
Ensembl chr 4:123,865,725...123,962,881
JBrowse link
G Fgf12 fibroblast growth factor 12 affects expression EXP Cocaine affects the expression of FGF12 mRNA CTD PMID:20187946 NCBI chr11:75,606,360...76,171,078
Ensembl chr11:75,905,443...76,168,989
JBrowse link
G Fgf2 fibroblast growth factor 2 decreases expression ISO Cocaine results in decreased expression of FGF2 mRNA CTD PMID:12629581 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 increases expression EXP Cocaine results in increased expression of FGFR1 mRNA CTD PMID:16076954 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fh fumarate hydratase affects expression ISO Cocaine affects the expression of FH1 protein CTD PMID:19393250 NCBI chr13:93,651,486...93,677,371
Ensembl chr13:93,651,484...93,677,377
JBrowse link
G Fis1 fission, mitochondrial 1 increases expression ISO Cocaine results in increased expression of FIS1 mRNA CTD PMID:31494168 NCBI chr12:22,750,485...22,765,324
Ensembl chr12:22,750,485...22,765,308
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B affects expression EXP Cocaine affects the expression of FKBP1B mRNA CTD PMID:20187946 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Fkbpl FKBP prolyl isomerase like affects expression EXP Cocaine affects the expression of FKBPL mRNA CTD PMID:20187946 NCBI chr20:4,411,890...4,413,360
Ensembl chr20:4,411,876...4,413,366
JBrowse link
G Flrt3 fibronectin leucine rich transmembrane protein 3 increases expression ISO Cocaine results in increased expression of FLRT3 mRNA CTD PMID:18000554 NCBI chr 3:134,684,446...134,696,586
Ensembl chr 3:134,683,065...134,696,654
JBrowse link
G Flywch1 FLYWCH-type zinc finger 1 decreases expression EXP Cocaine results in decreased expression of FLYWCH1 mRNA CTD PMID:17898221 NCBI chr10:13,087,925...13,107,833
Ensembl chr10:13,087,914...13,107,771
JBrowse link
G Fmr1 FMRP translational regulator 1 decreases expression EXP Cocaine results in decreased expression of FMR1 mRNA CTD PMID:24810662 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fndc1 fibronectin type III domain containing 1 multiple interactions ISO [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA CTD PMID:18355967 NCBI chr 1:47,605,211...47,687,499
Ensembl chr 1:47,605,262...47,687,504
JBrowse link
G Fndc5 fibronectin type III domain containing 5 affects expression EXP Cocaine affects the expression of FNDC5 mRNA CTD PMID:20187946 NCBI chr 5:147,323,240...147,330,266
Ensembl chr 5:147,323,240...147,330,266
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
affects expression
increases phosphorylation
decreases response to substance
increases activity
decreases expression
ISO
EXP
[Cocaine co-treated with SLC6A3 protein] results in increased expression of FOS protein; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS mRNA]; Cocaine inhibits the reaction [[Dopamine co-treated with SLC6A3 protein] results in increased expression of FOS protein]
Cocaine results in increased expression of FOS mRNA; Cocaine results in increased expression of FOS protein
Cocaine affects the expression of FOS mRNA; Cocaine affects the expression of FOS protein
Cocaine results in increased phosphorylation of FOS protein
[Morphine co-treated with Cocaine] affects the expression of FOS; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; Alcohols promotes the reaction [Cocaine results in increased expression of FOS protein]; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; Chloral Hydrate inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [[SK&F 81297 co-treated with Quinpirole] results in increased expression of FOS protein]; Cocaine promotes the reaction [Cocaine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [Ethanol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of FOS protein]; ecopipam inhibits the reaction [Cocaine results in increased expression of FOS protein]; Ethanol promotes the reaction [Cocaine results in increased expression of FOS protein]; Muscimol inhibits the reaction [Cocaine results in increased expression of FOS protein]; NPPC protein inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; Reserpine inhibits the reaction [Cocaine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOS protein]; Urethane inhibits the reaction [Cocaine results in increased expression of FOS protein]; volinanserin inhibits the reaction [Cocaine results in increased expression of FOS protein]
FOS protein mutant form results in decreased susceptibility to Cocaine
Cocaine results in increased activity of FOS protein
Cocaine results in decreased expression of FOS protein
[[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of NEO1 protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of PDYN protein; [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein] which affects the expression of SYT7 protein; [Cocaine co-treated with Caffeine] results in increased expression of FOS mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ATPAF1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CD4 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of CORO7 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ENTPD3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of FNDC1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of ITPR1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of NEXN mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PBX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PER1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PINX1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PKNOX2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PLPP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of PRKCZ mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SHANK3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of SYT9 mRNA; [Cocaine co-treated with FOS protein mutant form] results in decreased expression of THRA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of ADGRA1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAB39L mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CAMK1G mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of CBLN1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of GRIP1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of INA mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of LARGE1 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of NRIP3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SATB2 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of SORCS3 mRNA; [Cocaine co-treated with FOS protein mutant form] results in increased expression of TENM4 mRNA; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein; Baclofen inhibits the reaction [Cocaine results in increased expression of FOS protein]; CDK5R1 protein inhibits the reaction [Cocaine affects the expression of FOS mRNA]; CDK5R1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; CNR1 mutant form inhibits the reaction [Cocaine results in increased expression of FOS protein]; Cocaine promotes the reaction [Caffeine results in increased expression of FOS mRNA]; Cocaine promotes the reaction [DRD1 protein results in increased expression of FOS protein]; Cocaine promotes the reaction [DRD3 protein results in decreased expression of FOS protein]; cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester inhibits the reaction [Cocaine results in increased expression of FOS protein]; DRD3 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of BDNF mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of CALR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of DLK2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HOMER2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HS3ST2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of MAPK11 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NCALD mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NPTXR mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of NRN1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of PRKCA mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SATB1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of SEZ6L mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP1B3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ATP8B2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CLK1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of CTSB mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of EIF4B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KCNT1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of KDM3A mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LIN7B mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of LZTS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of MEPCE mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NIT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of NOS3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PBX3 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PPP1R7 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PRPF18 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of PTPRV mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SBSN mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYNE1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of SYT2 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of TSPOAP1 mRNA]; FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of ZFPM1 mRNA]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOS protein]; N-methyl-3-(bis(4'-fluorophenyl)methoxy)tropane inhibits the reaction [Cocaine results in increased expression of FOS protein]; NTRK2 protein affects the reaction [Cocaine affects the expression of FOS protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in increased expression of FOS protein]; RPS6KA3 affects the reaction [Cocaine results in increased phosphorylation of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased activity of FOS protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS mRNA]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOS protein]
CTD PMID:1498673, PMID:2118661, PMID:7905595, PMID:10415707, PMID:10521585, PMID:10632609, PMID:10814832, PMID:10904129, PMID:10943692, PMID:10971643, PMID:11160452, PMID:11172061, PMID:11403691, PMID:11421588, PMID:11716816, PMID:11739600, PMID:11860464, PMID:11882344, PMID:12112414, PMID:12122080, PMID:12128156, PMID:12379259, PMID:12419516, PMID:12581847, PMID:12670717, PMID:12699766, PMID:12786985, PMID:12821175, PMID:14644470, PMID:14741756, PMID:15056714, PMID:15219685, PMID:15254092, PMID:15295023, PMID:15665076, PMID:15814102, PMID:16179556, PMID:16263220, PMID:16300424, PMID:16339038, PMID:16395306, PMID:16459018, PMID:16710312, PMID:16930414, PMID:16962079, PMID:17276011, PMID:17596442, PMID:17851536, PMID:18164822, PMID:18311559, PMID:18355967, PMID:18396266, PMID:18479823, PMID:18822274, PMID:18991842, PMID:19169671, PMID:19606084, PMID:19620976, PMID:20187946, PMID:20633205, PMID:20947769, PMID:25933444, PMID:27899881, PMID:31059705 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
affects expression
ISO
EXP
Cocaine results in increased expression of FOSB protein
DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein alternative form]; DRD1 protein affects the reaction [Cocaine results in increased expression of FOSB protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein]
Cocaine results in increased expression of FOSB mRNA; Cocaine results in increased expression of FOSB protein; Cocaine results in increased expression of FOSB protein alternative form
Cocaine affects the expression of FOSB mRNA; Cocaine affects the expression of FOSB protein
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein; [JUND protein results in decreased activity of FOSB protein] which results in decreased susceptibility to Cocaine; Cocaine inhibits the reaction [Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]]; Cocaine promotes the reaction [EHMT2 protein binds to FOSB protein]; EHMT2 protein inhibits the reaction [Cocaine results in increased expression of FOSB mRNA]; N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; PPP1R1B gene mutant form inhibits the reaction [Cocaine results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSB protein]; SL 327 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]
CTD PMID:10103106, PMID:11391778, PMID:11739600, PMID:12417638, PMID:15056714, PMID:15814102, PMID:15926929, PMID:16263220, PMID:16674926, PMID:16710312, PMID:17898221, PMID:18293355, PMID:18355967, PMID:18822274, PMID:20056891, PMID:20633205, PMID:27899881 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit affects expression
decreases expression
EXP
ISO
Cocaine affects the expression of FOSL1 mRNA
Cocaine results in decreased expression of FOSL1 mRNA
CTD PMID:12117546, PMID:12629581 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions
decreases expression
ISO Cocaine promotes the reaction [JUN protein binds to FOSL2 protein]
[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein; [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein] which results in increased expression of FOSL2 protein]; SL 327 inhibits the reaction [[Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] which results in increased expression of FOSL2 protein]
Cocaine results in decreased expression of FOSL2 protein
CTD PMID:15056714, PMID:15814102 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G Foxc2 forkhead box C2 decreases expression EXP Cocaine results in decreased expression of FOXC2 mRNA CTD PMID:17898221 NCBI chr19:53,044,379...53,047,081
Ensembl chr19:53,044,379...53,047,081
JBrowse link
G Foxo1 forkhead box O1 decreases expression EXP Cocaine results in decreased expression of FOXO1 mRNA CTD PMID:17898221 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 increases expression EXP Cocaine results in increased expression of FRAS1 mRNA CTD PMID:17898221 NCBI chr14:14,438,392...14,853,016
Ensembl chr14:14,439,082...14,689,554
JBrowse link
G Frem2 FRAS1 related extracellular matrix 2 decreases expression EXP Cocaine results in decreased expression of FREM2 mRNA CTD PMID:27899881 NCBI chr 2:142,747,501...142,885,604
Ensembl chr 2:142,747,501...142,885,604
JBrowse link
G Frmd5 FERM domain containing 5 decreases expression EXP Cocaine results in decreased expression of FRMD5 mRNA CTD PMID:17898221 NCBI chr 3:113,480,780...113,755,286
Ensembl chr 3:113,483,269...113,525,864
JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 affects expression EXP Cocaine affects the expression of FRS3 mRNA CTD PMID:20187946 NCBI chr 9:15,297,794...15,306,850
Ensembl chr 9:15,297,895...15,306,465
JBrowse link
G Fubp1 far upstream element binding protein 1 affects expression EXP Cocaine affects the expression of FUBP1 mRNA CTD PMID:20187946 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G Fut8 fucosyltransferase 8 affects expression EXP Cocaine affects the expression of FUT8 mRNA CTD PMID:20187946 NCBI chr 6:100,305,957...100,537,208
Ensembl chr 6:100,337,226...100,537,224
JBrowse link
G Fzd6 frizzled class receptor 6 affects expression EXP Cocaine affects the expression of FZD6 mRNA CTD PMID:20187946 NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression EXP Cocaine results in increased expression of G6PD protein CTD PMID:25100957 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 affects expression
increases expression
decreases expression
EXP Cocaine affects the expression of GABBR1 mRNA
Cocaine results in increased expression of GABBR1 mRNA
Cocaine results in decreased expression of GABBR1 mRNA
CTD PMID:11793422, PMID:16076954, PMID:20187946 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 decreases phosphorylation EXP Cocaine results in decreased phosphorylation of GABBR2 protein CTD PMID:12716959 NCBI chr 5:62,276,100...62,621,737
Ensembl chr 5:62,276,100...62,621,737
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 affects expression
multiple interactions
EXP
ISO
Cocaine affects the expression of GABRA1 protein
1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]
CTD PMID:20826313, PMID:23266428 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 increases expression EXP Cocaine results in increased expression of GABRB1 mRNA CTD PMID:17898221 NCBI chr14:38,631,192...39,112,598
Ensembl chr14:38,643,385...39,112,600
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 multiple interactions ISO 1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] CTD PMID:23266428 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 affects expression
multiple interactions
EXP Cocaine affects the expression of GABRB3 mRNA
Cocaine affects the phosphorylation of and affects the expression of GABRB3 protein
CTD PMID:20187946, PMID:20826313 NCBI chr 1:113,034,251...113,265,364
Ensembl chr 1:112,976,770...113,265,364
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 multiple interactions ISO 1-(3-chlorophenyl)piperazine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; 3,4-Methylenedioxyamphetamine promotes the reaction [Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [1-(3-chlorophenyl)piperazine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine promotes the reaction [3,4-Methylenedioxyamphetamine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]; Cocaine results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein] CTD PMID:23266428 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of GAD1 mRNA
Cocaine results in increased expression of GAD1 protein
CTD PMID:12629581, PMID:15295023, PMID:18611417 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gal galanin and GMAP prepropeptide multiple interactions ISO GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; GAL protein inhibits the reaction [Cocaine results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:19099295 NCBI chr 1:218,653,059...218,657,922
Ensembl chr 1:218,652,917...218,657,925
JBrowse link
G Galk1 galactokinase 1 affects expression EXP Cocaine affects the expression of GALK1 mRNA CTD PMID:20187946 NCBI chr10:104,560,322...104,564,499
Ensembl chr10:104,560,303...104,564,480
JBrowse link
G Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 increases expression EXP Cocaine results in increased expression of GALNT1 mRNA CTD PMID:17898221 NCBI chr18:16,141,062...16,187,271
Ensembl chr18:16,146,447...16,185,496
JBrowse link
G Galnt16 polypeptide N-acetylgalactosaminyltransferase 16 affects expression EXP Cocaine affects the expression of GALNT16 mRNA CTD PMID:20187946 NCBI chr 6:104,069,853...104,250,177
Ensembl chr 6:104,068,547...104,250,174
JBrowse link
G Gap43 growth associated protein 43 decreases expression ISO Cocaine results in decreased expression of GAP43 mRNA CTD PMID:12629581 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gas2 growth arrest-specific 2 affects expression ISO Cocaine affects the expression of GAS2 mRNA CTD PMID:15681117 NCBI chr 1:107,234,389...107,363,624
Ensembl chr 1:107,262,659...107,363,788
JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 increases expression ISO Cocaine results in increased expression of GCC1 mRNA CTD PMID:17205118 NCBI chr 4:55,708,040...55,719,884
Ensembl chr 4:55,709,096...55,713,620
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO Cocaine results in increased expression of GCLC mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLC mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLC mRNA]
CTD PMID:30393195 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit affects expression
increases expression
multiple interactions
EXP
ISO
Cocaine affects the expression of GCLM mRNA
Cocaine results in increased expression of GCLM mRNA
PRKCD protein affects the reaction [Cocaine results in increased expression of GCLM mRNA]; rottlerin promotes the reaction [Cocaine results in increased expression of GCLM mRNA]
CTD PMID:20187946, PMID:30393195 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdap1 ganglioside-induced differentiation-associated-protein 1 increases expression EXP Cocaine results in increased expression of GDAP1 protein CTD PMID:25100957 NCBI chr 5:1,328,963...1,347,946
Ensembl chr 5:1,328,913...1,347,921
JBrowse link
G Gdap1l1 ganglioside-induced differentiation-associated protein 1-like 1 decreases expression EXP Cocaine results in decreased expression of GDAP1L1 protein CTD PMID:25100957 NCBI chr 3:159,823,791...159,843,260
Ensembl chr 3:159,823,878...159,842,278
JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases expression EXP Cocaine results in decreased expression of GDNF mRNA CTD PMID:14622243 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Cocaine results in increased expression of GEM mRNA CTD PMID:15009677 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Gfap glial fibrillary acidic protein increases expression
decreases expression
affects expression
ISO
EXP
Cocaine results in increased expression of GFAP protein
Cocaine results in decreased expression of GFAP protein
Cocaine affects the expression of GFAP mRNA; Cocaine affects the expression of GFAP protein
CTD PMID:11391778, PMID:11882367, PMID:12670315, PMID:15814102, PMID:20187946 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gfra2 GDNF family receptor alpha 2 affects expression EXP Cocaine affects the expression of GFRA2 mRNA CTD PMID:12358776 NCBI chr15:52,557,004...52,648,984
Ensembl chr15:52,557,607...52,648,972
JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO
EXP
Cocaine inhibits the reaction [4-hydroxybutyric acid results in increased secretion of GH1 protein]; Cocaine inhibits the reaction [Sodium Oxybate results in increased expression of GH1 protein]
Cocaine inhibits the reaction [Clonidine results in increased secretion of GH1 protein]
CTD PMID:9413023, PMID:10657535, PMID:15099682 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Gid8 GID complex subunit 8 homolog affects expression EXP Cocaine affects the expression of GID8 mRNA CTD PMID:20187946 NCBI chr 3:176,217,128...176,223,645
Ensembl chr 3:176,217,128...176,223,645
JBrowse link
G Gimap1 GTPase, IMAP family member 1 affects expression EXP Cocaine affects the expression of GIMAP1 mRNA CTD PMID:20187946 NCBI chr 4:78,365,276...78,375,450
Ensembl chr 4:78,371,121...78,375,223
JBrowse link
G Gimap5 GTPase, IMAP family member 5 affects expression EXP Cocaine affects the expression of GIMAP5 mRNA CTD PMID:20187946 NCBI chr 4:78,377,228...78,386,683
Ensembl chr 4:78,378,144...78,385,577
JBrowse link
G Gins3 GINS complex subunit 3 decreases expression EXP Cocaine results in decreased expression of GINS3 mRNA CTD PMID:27899881 NCBI chr19:9,835,113...9,843,649
Ensembl chr19:9,835,057...9,843,673
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 affects expression EXP Cocaine affects the expression of GIPC1 mRNA CTD PMID:20187946 NCBI chr19:24,786,604...24,798,231
Ensembl chr19:24,786,628...24,798,233
JBrowse link
G Gja5 gap junction protein, alpha 5 increases expression EXP Cocaine results in increased expression of GJA5 mRNA CTD PMID:27899881 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Cocaine affects the expression of GJB1 mRNA; Cocaine affects the expression of GJB1 protein CTD PMID:10510198 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gjb2 gap junction protein, beta 2 decreases expression ISO Cocaine results in decreased expression of GJB2 mRNA CTD PMID:12629581 NCBI chr15:37,377,313...37,394,494
Ensembl chr15:37,377,316...37,383,277
JBrowse link
G Gjb5 gap junction protein, beta 5 decreases expression EXP Cocaine results in decreased expression of GJB5 mRNA CTD PMID:27899881 NCBI chr 5:145,422,034...145,440,558
Ensembl chr 5:145,422,357...145,423,172
JBrowse link
G Gjd2 gap junction protein, delta 2 affects expression EXP Cocaine affects the expression of GJD2 mRNA; Cocaine affects the expression of GJD2 protein CTD PMID:16138316 NCBI chr 3:105,467,480...105,470,475
Ensembl chr 3:105,467,480...105,470,475
JBrowse link
G Gli2 GLI family zinc finger 2 decreases expression EXP Cocaine results in decreased expression of GLI2 mRNA CTD PMID:27899881 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444
JBrowse link
G Glp2r glucagon-like peptide 2 receptor decreases expression EXP Cocaine results in decreased expression of GLP2R mRNA CTD PMID:17898221 NCBI chr10:54,260,290...54,323,839
Ensembl chr10:54,260,290...54,323,439
JBrowse link
G Glrx3 glutaredoxin 3 affects expression EXP Cocaine affects the expression of GLRX3 mRNA CTD PMID:20187946 NCBI chr 1:209,768,696...209,799,912
Ensembl chr 1:209,768,696...209,799,903
JBrowse link
G Gnao1 G protein subunit alpha o1 decreases expression
multiple interactions
ISO
EXP
Cocaine results in decreased expression of GNAO1 mRNA
[Cocaine affects the activity of PRKACA protein] which affects the phosphorylation of GNAO1 protein alternative form
CTD PMID:12629581, PMID:19457111 NCBI chr19:11,513,201...11,669,578
Ensembl chr19:11,513,201...11,669,578
JBrowse link
G Gnat1 G protein subunit alpha transducin 1 increases expression EXP Cocaine results in increased expression of GNAT1 mRNA CTD PMID:27899881 NCBI chr 8:116,433,302...116,438,038
Ensembl chr 8:116,433,302...116,438,038
JBrowse link
G Gnb1 G protein subunit beta 1 decreases expression
increases expression
ISO
EXP
Cocaine results in decreased expression of GNB1 mRNA
Cocaine results in increased expression of GNB1 mRNA
CTD PMID:12629581, PMID:16076954 NCBI chr 5:172,914,025...172,981,403
Ensembl chr 5:172,934,990...172,979,986
JBrowse link
G Gnb2 G protein subunit beta 2 affects expression EXP Cocaine affects the expression of GNB2 mRNA CTD PMID:20187946 NCBI chr12:22,229,079...22,234,096
Ensembl chr12:22,229,079...22,234,096
JBrowse link
G Gnb4 G protein subunit beta 4 multiple interactions ISO HDAC5 affects the reaction [Cocaine affects the expression of GNB4 mRNA] CTD PMID:17988634 NCBI chr 2:118,978,965...119,007,877
Ensembl chr 2:118,978,973...119,007,835
JBrowse link
G Gng12 G protein subunit gamma 12 affects expression EXP Cocaine affects the expression of GNG12 mRNA CTD PMID:20187946 NCBI chr 4:97,634,925...97,763,478
Ensembl chr 4:97,657,671...97,760,102
JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 decreases expression
multiple interactions
ISO Cocaine results in decreased expression of GNRH1 protein
GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; prolinedithiocarbamate inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]
CTD PMID:31059705 NCBI chr15:44,441,856...44,446,064
Ensembl chr15:44,442,555...44,442,875
Ensembl chr15:44,442,555...44,442,875
JBrowse link
G Gp2 glycoprotein 2 affects expression EXP Cocaine affects the expression of GP2 mRNA CTD PMID:20187946 NCBI chr 1:189,166,735...189,182,306
Ensembl chr 1:189,166,399...189,182,306
JBrowse link
G Gpc5 glypican 5 increases expression
multiple interactions
ISO Cocaine results in increased expression of GPC5 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in increased expression of GPC5 mRNA]
CTD PMID:18355967 NCBI chr15:100,283,131...101,776,838 JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression EXP Cocaine results in increased expression of GPER1 mRNA CTD PMID:17898221 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Gphn gephyrin increases phosphorylation
multiple interactions
EXP Cocaine results in increased phosphorylation of GPHN protein
Win 55212-2 promotes the reaction [Cocaine results in increased phosphorylation of GPHN protein]
CTD PMID:32312805 NCBI chr 6:101,327,874...101,859,169
Ensembl chr 6:101,532,518...101,859,164
JBrowse link
G Gpm6a glycoprotein m6a decreases expression ISO Cocaine results in decreased expression of GPM6A mRNA CTD PMID:12629581 NCBI chr16:39,367,697...39,719,292
Ensembl chr16:39,367,692...39,719,187
JBrowse link
G Gpm6b glycoprotein m6b decreases expression ISO Cocaine results in decreased expression of GPM6B mRNA CTD PMID:12629581 NCBI chr  X:29,604,607...29,751,174
Ensembl chr  X:29,607,075...29,648,403
JBrowse link
G Gpr157 G protein-coupled receptor 157 decreases expression EXP Cocaine results in decreased expression of GPR157 mRNA CTD PMID:27899881 NCBI chr 5:167,109,691...167,125,380
Ensembl chr 5:167,109,691...167,125,380
JBrowse link
G Gpr3 G protein-coupled receptor 3 increases expression EXP Cocaine results in increased expression of GPR3 mRNA CTD PMID:27899881 NCBI chr 5:151,394,118...151,397,634
Ensembl chr 5:151,394,524...151,397,603
JBrowse link
G Gpr88 G-protein coupled receptor 88 affects expression EXP Cocaine affects the expression of GPR88 mRNA CTD PMID:20187946 NCBI chr 2:219,258,346...219,263,819
Ensembl chr 2:219,258,347...219,262,901
JBrowse link
G Gprasp1 G protein-coupled receptor associated sorting protein 1 affects expression EXP Cocaine affects the expression of GPRASP1 mRNA CTD PMID:20187946 NCBI chr  X:106,306,795...106,313,904
Ensembl chr  X:106,306,795...106,313,853
JBrowse link
G Gpsm1 G-protein signaling modulator 1 affects expression EXP Cocaine affects the expression of GPSM1 protein CTD PMID:15091342 NCBI chr 3:3,767,394...3,794,360
Ensembl chr 3:3,767,394...3,794,359
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
ISO PRKCD protein affects the reaction [Cocaine results in increased activity of GPT protein]; rottlerin inhibits the reaction [Cocaine results in increased activity of GPT protein] CTD PMID:30393195 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
affects response to substance
multiple interactions
ISO Cocaine results in increased expression of GPX1 protein
GPX1 protein affects the susceptibility to Cocaine
GPX1 protein affects the susceptibility to [Cocaine co-treated with prolinedithiocarbamate]; GPX1 protein inhibits the reaction [Cocaine affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in decreased expression of GNRH1 protein]; GPX1 protein inhibits the reaction [Cocaine results in increased activity of and affects the localization of RELA protein]; GPX1 protein inhibits the reaction [Cocaine results in increased expression of FOS protein]; prolinedithiocarbamate promotes the reaction [Cocaine results in increased expression of GPX1 protein]
CTD PMID:31059705 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Grb2 growth factor receptor bound protein 2 increases expression EXP Cocaine results in increased expression of GRB2 protein CTD PMID:25100957 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases response to substance
decreases expression
increases phosphorylation
affects response to substance
increases response to substance
increases expression
decreases phosphorylation
multiple interactions
affects expression
ISO
EXP
GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in decreased expression of GRIA1 mRNA; Cocaine results in decreased expression of GRIA1 protein
Cocaine results in increased phosphorylation of GRIA1 protein
GRIA1 protein affects the susceptibility to Cocaine
GRIA1 protein results in increased susceptibility to Cocaine
GRIA1 protein mutant form results in decreased susceptibility to Cocaine; GRIA1 results in decreased susceptibility to Cocaine
Cocaine results in increased expression of GRIA1 mRNA; Cocaine results in increased expression of GRIA1 protein
Cocaine results in decreased phosphorylation of GRIA1 protein
6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIA1 protein]; Cocaine affects the phosphorylation of and affects the expression of GRIA1 protein; Cocaine results in increased phosphorylation of and results in increased transport of GRIA1 protein; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]; ILK mutant form inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; Ondansetron inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; roscovitine inhibits the reaction [Cocaine results in decreased phosphorylation of GRIA1 protein]; U 0126 inhibits the reaction [Cocaine results in increased expression of GRIA1 protein]
Cocaine affects the expression of GRIA1 mRNA; Cocaine affects the expression of GRIA1 protein
Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein; Nifedipine inhibits the reaction [Cocaine results in increased expression of and results in increased phosphorylation of GRIA1 protein]; resveratrol promotes the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]; SL 327 inhibits the reaction [Cocaine results in increased phosphorylation of GRIA1 protein]
CTD PMID:9886066, PMID:11268215, PMID:11801363, PMID:12511956, PMID:12787079, PMID:14684464, PMID:15140200, PMID:16473939, PMID:16794574, PMID:17680995, PMID:17898221, PMID:18278040, PMID:18430032, PMID:18701074, PMID:19070590, PMID:19105975, PMID:19457111, PMID:19474322, PMID:19629758, PMID:20187946, PMID:20600170, PMID:23499958, PMID:24810662, PMID:28194001 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression
decreases response to substance
multiple interactions
affects expression
ISO
EXP
Cocaine results in increased expression of GRIA2 protein
GRIA2 results in decreased susceptibility to Cocaine
Cocaine results in increased phosphorylation of and affects the localization of GRIA2 protein
Cocaine results in increased expression of GRIA2 mRNA
Cocaine affects the expression of GRIA2 mRNA; Cocaine affects the expression of GRIA2 protein
CTD PMID:9886066, PMID:12511956, PMID:12787079, PMID:15140200, PMID:16363995, PMID:18945913, PMID:19105975, PMID:20187946, PMID:20534846 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 decreases expression
affects expression
increases expression
ISO
EXP
Cocaine results in decreased expression of GRIA3 mRNA
Cocaine affects the expression of GRIA3 protein
Cocaine results in increased expression of GRIA3 protein
CTD PMID:9886066, PMID:12511956, PMID:15140200, PMID:16363995 NCBI chr  X:127,561,843...127,829,763
Ensembl chr  X:127,562,660...127,829,753
JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 affects expression ISO
EXP
Cocaine affects the expression of GRIA4 mRNA
Cocaine affects the expression of GRIA4 protein
CTD PMID:9886066, PMID:15140200 NCBI chr 8:1,548,145...2,045,874
Ensembl chr 8:1,548,146...2,045,817
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 affects expression EXP Cocaine affects the expression of GRIK1 mRNA; Cocaine affects the expression of GRIK1 protein CTD PMID:12358776, PMID:15140200 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 affects expression EXP Cocaine affects the expression of GRIK2 protein CTD PMID:15140200 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 affects expression EXP Cocaine affects the expression of GRIK3 protein CTD PMID:15140200 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 affects expression EXP Cocaine affects the expression of GRIK5 protein CTD PMID:15140200 NCBI chr 1:81,885,516...81,946,731
Ensembl chr 1:81,885,521...81,946,714
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions
affects response to substance
increases expression
affects phosphorylation
affects expression
decreases expression
EXP
ISO
6-methyl-2-(phenylethynyl)pyridine affects the reaction [Cocaine affects the phosphorylation of GRIN1 protein]; Cocaine affects the phosphorylation of and affects the expression of GRIN1 protein; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIN1 protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIN1 protein]
GRIN1 protein affects the susceptibility to Cocaine
Cocaine results in increased expression of GRIN1 mRNA; Cocaine results in increased expression of GRIN1 protein
Cocaine affects the expression of GRIN1 mRNA; Cocaine affects the expression of GRIN1 protein
Cocaine results in decreased expression of GRIN1 mRNA
CTD PMID:9886066, PMID:11032893, PMID:11801363, PMID:12457264, PMID:12670717, PMID:12787079, PMID:15140200, PMID:16363995, PMID:17680995, PMID:19474322, PMID:20187946, PMID:20600170 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A multiple interactions
increases expression
affects expression
ISO
EXP
HDAC5 affects the reaction [Cocaine affects the expression of GRIN2A mRNA]
ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIN2A protein]
Cocaine results in increased expression of GRIN2A mRNA; Cocaine results in increased expression of GRIN2A protein
Cocaine affects the expression of GRIN2A mRNA; Cocaine affects the expression of GRIN2A protein
CTD PMID:17898221, PMID:17988634, PMID:19105975, PMID:19306440, PMID:19474322, PMID:20187946 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases expression
affects response to substance
multiple interactions
affects expression
decreases phosphorylation
EXP Cocaine results in increased expression of GRIN2B protein
GRIN2B protein affects the susceptibility to Cocaine
Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of GRIN2B protein]; ifenprodil inhibits the reaction [Cocaine results in increased expression of GRIN2B protein]; Ondansetron inhibits the reaction [Cocaine results in decreased phosphorylation of GRIN2B protein]; Ondansetron inhibits the reaction [Cocaine results in increased expression of GRIN2B protein]
Cocaine affects the expression of GRIN2B mRNA; Cocaine affects the expression of GRIN2B protein
CTD PMID:11032893, PMID:11801363, PMID:15140200, PMID:16794574, PMID:19105975, PMID:19306440, PMID:19474322, PMID:20187946 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C affects expression EXP Cocaine affects the expression of GRIN2C mRNA CTD PMID:20187946 NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D increases expression
affects expression
EXP Cocaine results in increased expression of GRIN2D mRNA
Cocaine affects the expression of GRIN2D mRNA
CTD PMID:16076954, PMID:20187946 NCBI chr 1:101,819,068...101,859,146
Ensembl chr 1:101,820,461...101,856,881
JBrowse link
G Grin3a glutamate ionotropic receptor NMDA type subunit 3A affects expression EXP Cocaine affects the expression of GRIN3A protein CTD PMID:15140200 NCBI chr 5:64,928,620...65,073,012
Ensembl chr 5:64,928,620...65,073,012
JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B affects expression EXP Cocaine affects the expression of GRIN3B protein CTD PMID:15140200 NCBI chr 7:12,764,993...12,771,310
Ensembl chr 7:12,764,993...12,771,310
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression EXP Cocaine results in increased expression of GRINA mRNA CTD PMID:16076954 NCBI chr 7:117,304,742...117,307,916
Ensembl chr 7:117,304,742...117,307,916
JBrowse link
G Grip1 glutamate receptor interacting protein 1 increases phosphorylation
multiple interactions
EXP
ISO
Cocaine results in increased phosphorylation of GRIP1 protein
[Cocaine co-treated with FOS protein mutant form] results in increased expression of GRIP1 mRNA
CTD PMID:18355967, PMID:19439608 NCBI chr 7:64,672,723...64,854,939
Ensembl chr 7:64,672,722...64,864,404
JBrowse link
G Grip2 glutamate receptor interacting protein 2 increases expression EXP Cocaine results in increased expression of GRIP2 mRNA CTD PMID:16076954 NCBI chr 4:123,585,184...123,636,040
Ensembl chr 4:123,586,231...123,636,040
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 affects expression
increases expression
EXP Cocaine affects the expression of GRK2 mRNA
Cocaine results in increased expression of GRK2 mRNA
CTD PMID:16076954, PMID:20187946 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Grk6 G protein-coupled receptor kinase 6 affects expression EXP Cocaine affects the expression of GRK6 mRNA CTD PMID:20187946 NCBI chr17:9,705,917...9,721,921
Ensembl chr17:9,703,453...9,721,574
JBrowse link
G Grm1 glutamate metabotropic receptor 1 affects response to substance ISO GRM1 affects the susceptibility to Cocaine CTD PMID:19597494 NCBI chr 1:4,753,141...5,165,859
Ensembl chr 1:4,753,144...5,165,859
JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases activity
affects expression
decreases activity
EXP Cocaine results in increased activity of GRM2 protein
Cocaine affects the expression of GRM2 protein
Cocaine results in decreased activity of GRM2 protein
CTD PMID:18673447, PMID:19105975, PMID:20416862 NCBI chr 8:115,344,999...115,358,628
Ensembl chr 8:115,344,999...115,358,046
JBrowse link
G Grm3 glutamate metabotropic receptor 3 increases activity
affects expression
EXP Cocaine results in increased activity of GRM3 protein
Cocaine affects the expression of GRM3 protein
CTD PMID:19105975, PMID:20416862 NCBI chr 4:21,316,761...21,567,561
Ensembl chr 4:21,317,695...21,560,490
JBrowse link
G Grm5 glutamate metabotropic receptor 5 affects expression
multiple interactions
increases expression
affects localization
decreases response to substance
ISO
EXP
Cocaine affects the expression of GRM5 mRNA
Cocaine results in decreased expression of and results in decreased activity of GRM5 protein
Cocaine results in increased expression of GRM5 mRNA
Cocaine affects the expression of GRM5 protein
Cocaine affects the localization of GRM5 protein
GRM5 mutant form results in decreased susceptibility to Cocaine
CTD PMID:9886066, PMID:15295029, PMID:17898221, PMID:19105975, PMID:19118598, PMID:20416862, PMID:20534846, PMID:20826661, PMID:24810662 NCBI chr 1:151,207,846...151,785,038
Ensembl chr 1:151,439,409...151,783,392
JBrowse link
G Grm7 glutamate metabotropic receptor 7 increases expression EXP Cocaine results in increased expression of GRM7 mRNA CTD PMID:16076954 NCBI chr 4:142,452,616...143,368,460
Ensembl chr 4:142,780,987...143,367,578
JBrowse link
G Grpr gastrin releasing peptide receptor affects expression EXP Cocaine affects the expression of GRPR mRNA CTD PMID:20187946 NCBI chr  X:32,746,259...32,786,266
Ensembl chr  X:32,745,873...32,786,359
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha affects expression EXP Cocaine affects the expression of GSK3A mRNA CTD PMID:12117546 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases activity
ISO Cocaine results in decreased phosphorylation of and results in increased activity of GSK3B protein
Cocaine results in increased activity of GSK3B protein
CTD PMID:19328817 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin decreases expression ISO Cocaine results in decreased expression of GSN mRNA CTD PMID:12629581 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gsr glutathione-disulfide reductase increases expression EXP Cocaine deficiency results in increased expression of GSR mRNA CTD PMID:22860061 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsto1 glutathione S-transferase omega 1 affects expression ISO Cocaine affects the expression of GSTO1 protein CTD PMID:19393250 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects response to substance ISO GSTP1 polymorphism affects the susceptibility to Cocaine CTD PMID:16272961 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 increases expression EXP Cocaine results in increased expression of GUCY1A1 mRNA CTD PMID:17898221 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression EXP Cocaine results in increased expression of GUCY1B1 mRNA CTD PMID:17898221 NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024
JBrowse link
G Gyg1 glycogenin 1 decreases expression EXP Cocaine results in decreased expression of GYG1 protein CTD PMID:25100957 NCBI chr 2:104,916,734...104,958,219
Ensembl chr 2:104,916,738...104,958,034
JBrowse link
G Gzmm granzyme M affects expression EXP Cocaine affects the expression of GZMM mRNA CTD PMID:20187946 NCBI chr 7:12,893,431...12,899,004
Ensembl chr 7:12,893,432...12,899,004
JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 affects expression EXP Cocaine affects the expression of HAND1 mRNA CTD PMID:20187946 NCBI chr10:43,250,729...43,253,296
Ensembl chr10:43,250,745...43,253,296
JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 increases expression ISO Cocaine results in increased expression of HCN2 mRNA CTD PMID:18000554 NCBI chr 7:12,851,730...12,870,087
Ensembl chr 7:12,851,739...12,874,215
JBrowse link
G Hcrt hypocretin neuropeptide precursor affects expression
multiple interactions
EXP Cocaine affects the expression of HCRT mRNA
Methadone affects the reaction [Cocaine affects the expression of HCRT mRNA]
CTD PMID:18990547 NCBI chr10:88,669,216...88,670,430
Ensembl chr10:88,669,214...88,670,430
JBrowse link
G Hcrtr2 hypocretin receptor 2 affects expression EXP Cocaine affects the expression of HCRTR2 protein CTD PMID:17623047 NCBI chr 8:83,307,684...83,421,612
Ensembl chr 8:83,307,684...83,421,612
JBrowse link
G Hdac10 histone deacetylase 10 affects expression EXP Cocaine affects the expression of HDAC10 mRNA CTD PMID:20187946 NCBI chr 7:130,102,335...130,109,036
Ensembl chr 7:130,102,347...130,107,437
JBrowse link
G Hdac5 histone deacetylase 5 decreases activity
decreases response to substance
multiple interactions
ISO Cocaine results in decreased activity of HDAC5 protein
HDAC5 results in decreased susceptibility to Cocaine
Cocaine results in increased phosphorylation of and results in increased localization of HDAC5 protein; HDAC5 affects the reaction [Cocaine affects the expression of ABCA5 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of ADAM1A mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of CUEDC1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of ERBIN mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of GNB4 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of GRIN2A mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of KCNK4 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of KCNQ5 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of PRM1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of RAPGEF6 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of RGS20 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of SUV39H1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of TACR1 mRNA]; HDAC5 affects the reaction [Cocaine affects the expression of WNT5A mRNA]
CTD PMID:17988634 NCBI chr10:90,140,183...90,169,853
Ensembl chr10:90,140,183...90,151,042
JBrowse link
G Hdac6 histone deacetylase 6 multiple interactions
decreases expression
EXP Win 55212-2 promotes the reaction [Cocaine results in decreased expression of HDAC6 protein] CTD PMID:32312805 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Hdc histidine decarboxylase affects response to substance ISO HDC gene mutant form affects the susceptibility to Cocaine CTD PMID:17072589 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hecw2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 decreases expression EXP Cocaine results in decreased expression of HECW2 mRNA CTD PMID:17898221 NCBI chr 9:60,451,476...60,843,160
Ensembl chr 9:60,457,215...60,672,246
JBrowse link
G Herc1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 increases expression EXP Cocaine results in increased expression of HERC1 mRNA CTD PMID:17898221 NCBI chr 8:72,029,550...72,198,363
Ensembl chr 8:72,029,489...72,198,358
JBrowse link
G Hhip Hedgehog-interacting protein decreases expression EXP Cocaine results in decreased expression of HHIP mRNA CTD PMID:17898221 NCBI chr19:31,525,134...31,614,487
Ensembl chr19:31,524,671...31,614,246
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Cocaine results in decreased expression of HIF1A mRNA CTD PMID:12629581 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A affects expression
increases expression
EXP Cocaine affects the expression of HIGD1A mRNA
Cocaine results in increased expression of HIGD1A protein
CTD PMID:20187946, PMID:25100957 NCBI chr 8:130,482,492...130,491,888
Ensembl chr 8:130,482,493...130,491,998
JBrowse link
G Hmga1 high mobility group AT-hook 1 affects expression EXP Cocaine affects the expression of HMGA1 mRNA CTD PMID:20187946 NCBI chr20:7,132,501...7,140,155
Ensembl chr20:7,136,007...7,138,980
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP Cocaine results in increased expression of HMGCS1 mRNA CTD PMID:12117546 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Homer1 homer scaffold protein 1 increases response to substance
increases expression
affects expression
multiple interactions
decreases response to substance
ISO
EXP
HOMER1 polymorphism results in increased susceptibility to Cocaine
Cocaine results in increased expression of HOMER1 protein
Cocaine affects the expression of HOMER1 mRNA; Cocaine affects the expression of HOMER1 protein
Cocaine affects the expression of and affects the localization of HOMER1 protein
HOMER1 protein results in decreased susceptibility to Cocaine
Cocaine results in increased expression of HOMER1 mRNA
CTD PMID:15294147, PMID:16314758, PMID:18355967, PMID:19105975, PMID:19118598, PMID:19306440, PMID:20187946, PMID:20534846 NCBI chr 2:22,909,550...23,012,303
Ensembl chr 2:22,909,569...23,009,678
JBrowse link
G Homer2 homer scaffold protein 2 multiple interactions
affects expression
decreases response to substance
decreases expression
ISO
EXP
Cocaine affects the reaction [HOMER2 mutant form results in decreased secretion of Excitatory Amino Acid Agents]; FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HOMER2 mRNA]
Cocaine affects the expression of HOMER2 mRNA
HOMER2 protein results in decreased susceptibility to Cocaine; HOMER2 results in decreased susceptibility to Cocaine
CTD PMID:14684444, PMID:15294147, PMID:15545022, PMID:18355967, PMID:20187946 NCBI chr 1:143,443,300...143,535,579
Ensembl chr 1:143,443,300...143,535,583
JBrowse link
G Homer3 homer scaffold protein 3 affects expression EXP Cocaine affects the expression of HOMER3 mRNA CTD PMID:20187946 NCBI chr16:20,880,447...20,890,968
Ensembl chr16:20,881,518...20,890,949
JBrowse link
G Hpcal1 hippocalcin-like 1 decreases expression ISO Cocaine results in decreased expression of HPCAL1 mRNA CTD PMID:15009677 NCBI chr 6:43,001,920...43,109,083
Ensembl chr 6:43,001,948...43,109,071
JBrowse link
G Hpcal4 hippocalcin-like 4 affects expression
increases expression
EXP Cocaine affects the expression of HPCAL4 mRNA
Cocaine results in increased expression of HPCAL4 mRNA
CTD PMID:17898221, PMID:20187946 NCBI chr 5:140,870,127...140,882,242
Ensembl chr 5:140,870,140...140,882,244
JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase increases expression EXP Cocaine results in increased expression of HPD mRNA CTD PMID:27899881 NCBI chr12:38,828,606...38,839,956
Ensembl chr12:38,828,444...38,839,969
JBrowse link
G Hps1 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 affects expression EXP Cocaine affects the expression of HPS1 mRNA CTD PMID:20187946 NCBI chr 1:261,989,178...262,015,282
Ensembl chr 1:261,989,178...262,015,153
JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 decreases expression
multiple interactions
ISO Cocaine results in decreased expression of HS3ST2 mRNA
FOS protein mutant form inhibits the reaction [Cocaine results in decreased expression of HS3ST2 mRNA]
CTD PMID:18355967 NCBI chr 1:191,344,979...191,474,143
Ensembl chr 1:191,344,979...191,474,142
JBrowse link
G Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 decreases expression EXP Cocaine results in decreased expression of HSD17B6 mRNA CTD PMID:17898221 NCBI chr 7:2,412,370...2,431,249
Ensembl chr 7:2,412,363...2,431,197
Ensembl chr13:2,412,363...2,431,197
JBrowse link
G Hsf1 heat shock transcription factor 1 affects expression EXP Cocaine affects the expression of HSF1 mRNA CTD PMID:20187946 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 increases expression EXP Cocaine deficiency results in increased expression of HSP90AA1 mRNA CTD PMID:22860061 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 decreases expression EXP Cocaine results in decreased expression of HSP90AB1 mRNA CTD PMID:17898221 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Cocaine results in increased expression of HSPA1A mRNA CTD PMID:20056891 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B affects expression
increases expression
ISO
EXP
Cocaine affects the expression of HSPA1B mRNA
Cocaine results in increased expression of HSPA1B mRNA
CTD PMID:15681117, PMID:27899881 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
ISO
EXP
Cocaine results in increased expression of HSPA5 mRNA
Cocaine results in increased expression of HSPA5 mRNA; Cocaine results in increased expression of HSPA5 protein
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; Dizocilpine Maleate inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; N-phenyl-7-(hydroxyimino)cyclopropa(b)chromen-1a-carboxamide inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]
CTD PMID:15009677, PMID:17303341, PMID:23644055 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 multiple interactions
increases expression
EXP Anisomycin inhibits the reaction [Cocaine results in increased expression of HSPA9 protein] CTD PMID:12422371 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP Cocaine results in increased expression of HSPB1 mRNA CTD PMID:27899881 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 affects expression ISO Cocaine affects the expression of HSPD1 protein CTD PMID:19393250 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 multiple interactions EXP [Win 55212-2 co-treated with Cocaine] results in decreased phosphorylation of HTATSF1 protein CTD PMID:32312805 NCBI chr  X:159,514,053...159,528,281
Ensembl chr  X:159,513,800...159,528,281
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP Cocaine inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin binds to HTR1A protein] CTD PMID:9723786 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B increases response to substance
affects activity
multiple interactions
ISO
EXP
HTR1B mutant form results in increased susceptibility to Cocaine
Cocaine affects the activity of HTR1B protein
[3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo(3,2-b)pyrid-5-one binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine; [5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine; [CP 94253 binds to and results in increased activity of HTR1B protein] which affects the susceptibility to Cocaine
CTD PMID:9603521, PMID:9822762, PMID:17074068 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D affects expression EXP Cocaine affects the expression of HTR1D mRNA CTD PMID:20187946 NCBI chr 5:154,780,958...154,801,505
Ensembl chr 5:154,800,226...154,801,350
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
affects activity
affects response to substance
ISO
EXP
[alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Alprenolol co-treated with Cocaine] affects the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine]; [Metergoline binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Methiothepin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Mianserin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine; [Yohimbine co-treated with Cocaine] affects the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine]; Cocaine inhibits the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine]
Cocaine affects the activity of HTR2A protein
Cocaine promotes the reaction [[4-iodo-2,5-dimethoxyphenylisopropylamine binds to and results in increased activity of HTR2A protein] which results in increased secretion of and results in increased abundance of Dopamine]; Ketanserin inhibits the reaction [Cocaine promotes the reaction [[4-iodo-2,5-dimethoxyphenylisopropylamine binds to and results in increased activity of HTR2A protein] which results in increased secretion of and results in increased abundance of Dopamine]]
HTR2A protein affects the susceptibility to Cocaine
CTD PMID:8392199, PMID:10764922, PMID:10773209, PMID:10773215, PMID:17259860 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions
decreases expression
increases response to substance
ISO
EXP
[1-(3-chlorophenyl)piperazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine; [6-chloro-2-(1-piperazinyl)pyrazine binds to and results in increased activity of HTR2C protein] which results in increased susceptibility to Cocaine; HTR2C protein affects the reaction [Cocaine results in increased abundance of Dopamine]
Cocaine results in decreased expression of HTR2C mRNA
HTR2C mutant form results in increased susceptibility to Cocaine
CTD PMID:10541732, PMID:12427861, PMID:16076954 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A decreases response to substance ISO HTR3A mutant form results in decreased susceptibility to Cocaine CTD PMID:17559417 NCBI chr 8:53,211,436...53,223,878
Ensembl chr 8:53,211,438...53,223,804
JBrowse link
G Htr4 5-hydroxytryptamine receptor 4 affects response to substance EXP HTR4 protein affects the susceptibility to Cocaine CTD PMID:9806222 NCBI chr18:57,637,013...57,820,317
Ensembl chr18:57,654,290...57,819,698
JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 multiple interactions EXP [Ro 4-6790 binds to and results in decreased activity of HTR6 protein] which results in decreased susceptibility to Cocaine; [SB 271046 binds to and results in decreased activity of HTR6 protein] which results in decreased susceptibility to Cocaine CTD PMID:20426879 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
G Hvcn1 hydrogen voltage-gated channel 1 decreases expression EXP Cocaine results in decreased expression of HVCN1 mRNA CTD PMID:27899881 NCBI chr12:39,822,814...39,851,093
Ensembl chr12:39,822,637...39,850,567
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression EXP Cocaine results in increased expression of ICAM1 mRNA CTD PMID:10864098 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Ice2 interactor of little elongation complex ELL subunit 2 affects response to substance ISO ICE2 gene SNP affects the susceptibility to Cocaine CTD PMID:18438686 NCBI chr 8:75,625,147...75,666,959
Ensembl chr 8:75,625,174...75,666,866
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha affects expression EXP Cocaine affects the expression of IDH3A mRNA CTD PMID:20187946 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Ier5 immediate early response 5 affects expression EXP Cocaine affects the expression of IER5 mRNA CTD PMID:20187946 NCBI chr13:72,742,210...72,744,302
Ensembl chr13:72,742,210...72,744,303
JBrowse link
G Ifng interferon gamma affects secretion
decreases expression
multiple interactions
ISO Cocaine affects the secretion of IFNG protein
Cocaine results in decreased expression of IFNG mRNA; Cocaine results in decreased expression of IFNG protein
[Cocaine co-treated with Heroin] results in increased expression of IFNG protein
CTD PMID:9787120, PMID:16766138, PMID:29673861 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 affects expression EXP Cocaine affects the expression of IFRD1 mRNA CTD PMID:20187946 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Ift81 intraflagellar transport 81 increases expression EXP Cocaine results in increased expression of IFT81 mRNA CTD PMID:17898221 NCBI chr12:39,420,161...39,507,412
Ensembl chr12:39,423,596...39,506,890
JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects expression EXP Cocaine affects the expression of IGF1R mRNA CTD PMID:20187946 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression EXP Cocaine results in decreased expression of IGF2 mRNA CTD PMID:16076954 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 decreases expression EXP Cocaine results in decreased expression of IGFBP2 mRNA CTD PMID:16076954 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Igsf8 immunoglobulin superfamily, member 8 affects expression EXP Cocaine affects the expression of IGSF8 mRNA CTD PMID:20187946 NCBI chr13:90,692,590...90,703,262
Ensembl chr13:90,692,666...90,700,789
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta affects expression EXP Cocaine affects the expression of IKBKB mRNA CTD PMID:20187946 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 multiple interactions
increases expression
decreases secretion
ISO [Cocaine co-treated with Heroin] results in increased expression of IL10 protein
Cocaine results in increased expression of IL10 protein
Cocaine results in decreased secretion of IL10 protein
CTD PMID:9787120, PMID:16766138 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il16 interleukin 16 decreases expression EXP Cocaine results in decreased expression of IL16 mRNA CTD PMID:27899881 NCBI chr 1:145,781,923...145,881,538
Ensembl chr 1:145,781,928...145,870,912
JBrowse link
G Il18bp interleukin 18 binding protein affects expression EXP Cocaine affects the expression of IL18BP mRNA CTD PMID:20187946 NCBI chr 1:167,091,521...167,095,727
Ensembl chr 1:167,091,522...167,093,560
JBrowse link
G Il1a interleukin 1 alpha affects expression EXP Cocaine affects the expression of IL1A mRNA CTD PMID:20187946 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta increases expression ISO Cocaine results in increased expression of IL1B mRNA CTD PMID:20948987, PMID:26558777 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Cocaine co-treated with Heroin] results in increased expression of IL2 protein CTD PMID:16766138 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il2ra interleukin 2 receptor subunit alpha decreases secretion ISO Cocaine results in decreased secretion of IL2RA protein CTD PMID:1452400 NCBI chr17:70,500,672...70,547,929
Ensembl chr17:70,499,083...70,548,071
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [Cocaine co-treated with Heroin] results in increased expression of IL4 protein CTD PMID:16766138 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il4i1 interleukin 4 induced 1 decreases expression EXP Cocaine results in decreased expression of IL4I1 mRNA CTD PMID:17898221 NCBI chr 1:100,811,727...100,836,901
Ensembl chr 1:100,830,064...100,836,677
JBrowse link
G Il6 interleukin 6 decreases expression
affects response to substance
multiple interactions
increases expression
ISO
EXP
Cocaine results in decreased expression of IL6 protein
IL6 protein affects the susceptibility to Cocaine
[IL6 protein affects the susceptibility to Cocaine] which affects the expression of TNF mRNA; [IL6 protein affects the susceptibility to Cocaine] which affects the expression of TNF protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased phosphorylation of JAK2 protein]]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide affects the reaction [IL6 protein affects the reaction [Cocaine results in increased phosphorylation of STAT3 protein]]; IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]; IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]; IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of ADCYAP1R1 mRNA]; IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]; IL6 protein affects the reaction [Cocaine results in increased phosphorylation of JAK2 protein]; IL6 protein affects the reaction [Cocaine results in increased phosphorylation of STAT3 protein]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2 protein]]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in decreased expression of BCL2L1 protein]]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased cleavage of CASP3 protein]]; TNF protein affects the reaction [IL6 protein affects the reaction [Cocaine results in increased expression of BAX protein]]; TNF protein affects the reaction [IL6 protein affects the susceptibility to Cocaine]
Cocaine results in increased expression of IL6 mRNA; Cocaine results in increased expression of IL6 protein
CTD PMID:10864098, PMID:17068203, PMID:29673861 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor affects response to substance ISO IL6R protein affects the susceptibility to Cocaine CTD PMID:29673861 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Ilk integrin-linked kinase multiple interactions
increases expression
EXP Cocaine affects the reaction [ILK protein affects the phosphorylation of AKT1 protein]; ILK mutant form in