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ONTOLOGY REPORT - ANNOTATIONS


Term:estriol
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Accession:CHEBI:27974 term browser browse the term
Definition:A 3-hydroxy steroid that is estra-1,3,5(10)-trien-3-ol substituted by additional hydroxy groups at positions 16 and 17 (16alpha,17beta-stereoisomer).
Synonyms:exact_synonym: estra-1,3,5(10)-triene-3,16alpha,17beta-triol
 related_synonym: (16alpha,17beta)-estra-1,3,5(10)-triene-3,16,17-triol;   1,3,5(10)-Estratriene-3,16-alpha,17beta-triol;   16alpha,17beta-estriol;   16alpha-hydroxyestradiol;   3,16alpha,17beta-trihydroxy-Delta(1,3,5)-estratriene;   Estriel;   Formula=C18H24O3;   InChI=1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1;   InChIKey=PROQIPRRNZUXQM-ZXXIGWHRSA-N;   SMILES=[H][C@]12CC[C@]3(C)[C@@H](O)[C@H](O)C[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21;   oestriol;   trihydroxyestrin
 alt_id: CHEBI:23969;   CHEBI:42467;   CHEBI:4869
 xref: Beilstein:2508172 "Beilstein";   CAS:50-27-1 "ChemIDplus";   CAS:50-27-1 "KEGG COMPOUND";   CAS:50-27-1 "NIST Chemistry WebBook";   DrugBank:DB04573;   Drug_Central:3187 "DrugCentral";   HMDB:HMDB0000153;   KEGG:C05141;   KEGG:D00185;   LINCS:LSM-2368;   LIPID_MAPS_instance:LMST02010003 "LIPID MAPS"
 xref_mesh: MESH:D004964
 xref: MetaCyc:ESTRIOL;   PDBeChem:ESL;   PMID:11133265 "Europe PMC";   PMID:23777262 "Europe PMC";   PMID:9373313 "Europe PMC";   Reaxys:2508172 "Reaxys";   VSDB:1907;   Wikipedia:Estriol


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estriol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Acrbp acrosin binding protein JBrowse link 4 157,563,990 157,577,045 RGD:6480464
G Actc1 actin, alpha, cardiac muscle 1 JBrowse link 3 105,507,403 105,512,939 RGD:6480464
G Afp alpha-fetoprotein JBrowse link 14 19,141,755 19,159,919 RGD:6480464
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:6480464
G Agtr1a angiotensin II receptor, type 1a JBrowse link 17 35,907,102 35,958,136 RGD:6480464
G Akap17a A-kinase anchoring protein 17A JBrowse link 12 18,527,116 18,531,780 RGD:6480464
G Akirin1 akirin 1 JBrowse link 5 141,415,226 141,430,627 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Amer1 APC membrane recruitment protein 1 JBrowse link X 64,686,620 64,702,504 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Arhgdia Rho GDP dissociation inhibitor alpha JBrowse link 10 109,754,012 109,757,506 RGD:6480464
G Aurkb aurora kinase B JBrowse link 10 55,625,860 55,632,399 RGD:6480464
G B3gntl1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 JBrowse link 10 110,799,409 110,863,075 RGD:6480464
G B4galt1 beta-1,4-galactosyltransferase 1 JBrowse link 5 57,121,768 57,168,610 RGD:6480464
G Bmf Bcl2 modifying factor JBrowse link 3 110,303,515 110,324,125 RGD:6480464
G Btbd10 BTB domain containing 10 JBrowse link 1 178,138,562 178,196,551 RGD:6480464
G C2cd2l C2CD2-like JBrowse link 8 48,641,792 48,652,119 RGD:6480464
G Ccn1 cellular communication network factor 1 JBrowse link 2 251,529,354 251,532,312 RGD:6480464
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:6480464
G Ccnb2 cyclin B2 JBrowse link 8 76,847,972 76,861,165 RGD:6480464
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:6480464
G Cd274 CD274 molecule JBrowse link 1 247,519,890 247,539,659 RGD:6480464
G Cd276 Cd276 molecule JBrowse link 8 63,312,060 63,350,411 RGD:6480464
G Cd80 Cd80 molecule JBrowse link 11 64,815,201 64,855,293 RGD:6480464
G Cd86 CD86 molecule JBrowse link 11 67,060,305 67,117,990 RGD:6480464
G Cd99l2 CD99 molecule-like 2 JBrowse link 15 5,265,257 5,311,232 RGD:6480464
G Cdc42se1 CDC42 small effector 1 JBrowse link 2 196,402,837 196,410,664 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Chst8 carbohydrate sulfotransferase 8 JBrowse link 1 90,542,095 90,685,257 RGD:6480464
G Ckb creatine kinase B JBrowse link 6 136,142,956 136,145,838 RGD:6480464
G Cnrip1 cannabinoid receptor interacting protein 1 JBrowse link 14 100,217,547 100,247,235 RGD:6480464
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 JBrowse link 19 52,647,038 52,705,118 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Dennd2a DENN domain containing 2A JBrowse link 4 67,242,257 67,342,993 RGD:6480464
G Dtx4 deltex E3 ubiquitin ligase 4 JBrowse link 1 228,729,842 228,759,783 RGD:6480464
G Egr1 early growth response 1 JBrowse link 18 27,657,903 27,660,101 RGD:6480464
G Egr3 early growth response 3 JBrowse link 15 51,756,683 51,762,080 RGD:6480464
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta JBrowse link 3 150,391,455 150,412,179 RGD:6480464
G Eno2 enolase 2 JBrowse link 4 157,285,192 157,294,090 RGD:6480464
G Esr1 estrogen receptor 1 JBrowse link 1 41,192,029 41,594,799 RGD:6480464
G Esr2 estrogen receptor 2 JBrowse link 6 99,163,953 99,214,711 RGD:6480464
G Etf1 eukaryotic translation termination factor 1 JBrowse link 18 27,698,693 27,725,694 RGD:6480464
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:6480464
G Fam102a family with sequence similarity 102, member A JBrowse link 3 11,554,084 11,586,315 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Foxa2 forkhead box A2 JBrowse link 3 142,383,084 142,387,493 RGD:6480464
G Gh1 growth hormone 1 JBrowse link 10 94,486,204 94,488,181 RGD:6480464
G Hnf4a hepatocyte nuclear factor 4, alpha JBrowse link 3 159,902,441 159,965,003 RGD:6480464
G Hoxa10 homeobox A10 JBrowse link 4 82,285,940 82,295,892 RGD:6480464
G Hoxa11 homeobox A11 JBrowse link 4 82,296,888 82,301,419 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:6480464
G Igfbp5 insulin-like growth factor binding protein 5 JBrowse link 9 80,154,230 80,166,813 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il12a interleukin 12A JBrowse link 2 165,076,945 165,083,996 RGD:6480464
G Il12b interleukin 12B JBrowse link 10 30,034,447 30,048,774 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il23a interleukin 23 subunit alpha JBrowse link 7 2,710,609 2,712,723 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Inhbb inhibin subunit beta B JBrowse link 13 35,436,532 35,442,222 RGD:6480464
G Ip6k2 inositol hexakisphosphate kinase 2 JBrowse link 8 117,574,136 117,599,849 RGD:6480464
G Jun Jun proto-oncogene, AP-1 transcription factor subunit JBrowse link 5 114,011,184 114,014,277 RGD:6480464
G Lpar4 lysophosphatidic acid receptor 4 JBrowse link X 78,042,859 78,056,347 RGD:6480464
G Lsm10 LSM10, U7 small nuclear RNA associated JBrowse link 5 144,106,339 144,108,703 RGD:6480464
G Mak16 MAK16 homolog JBrowse link 16 64,729,254 64,737,807 RGD:6480464
G Map2k1 mitogen activated protein kinase kinase 1 JBrowse link 8 69,134,218 69,722,573 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Nampt nicotinamide phosphoribosyltransferase JBrowse link 6 52,122,085 52,156,473 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464
G Nppc natriuretic peptide C JBrowse link 9 93,731,436 93,735,636 RGD:6480464
G Nup50 nucleoporin 50 JBrowse link 7 125,833,557 125,850,830 RGD:6480464
G Pdcd1lg2 programmed cell death 1 ligand 2 JBrowse link 1 247,562,202 247,629,279 RGD:6480464
G Pde12 phosphodiesterase 12 JBrowse link 16 2,357,028 2,367,069 RGD:6480464
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:6480464
G Pdzk1 PDZ domain containing 1 JBrowse link 2 198,965,685 198,999,323 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 JBrowse link 14 83,559,397 83,572,481 RGD:6480464
G Polg2 DNA polymerase gamma 2, accessory subunit JBrowse link 10 94,968,836 94,979,259 RGD:6480464
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B JBrowse link 13 49,933,155 49,940,961 RGD:6480464
G Ppp4r1 protein phosphatase 4, regulatory subunit 1 JBrowse link 9 113,515,312 113,573,308 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Prrx2 paired related homeobox 2 JBrowse link 3 9,681,871 9,718,051 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rrp1b ribosomal RNA processing 1B JBrowse link 20 10,844,234 10,869,830 RGD:6480464
G Sdc3 syndecan 3 JBrowse link 5 148,923,098 148,956,404 RGD:6480464
G Selenbp1 selenium binding protein 1 JBrowse link 2 196,105,592 196,146,474 RGD:6480464
G Shbg sex hormone binding globulin JBrowse link 10 56,219,861 56,237,354 RGD:6480464
G Sirt3 sirtuin 3 JBrowse link 1 213,613,502 213,636,061 RGD:6480464
G Slc12a2 solute carrier family 12 member 2 JBrowse link 18 52,917,124 52,985,281 RGD:6480464
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:6480464
G Slc7a6 solute carrier family 7 member 6 JBrowse link 19 38,152,225 38,179,149 RGD:6480464
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:6480464
G Stat5a signal transducer and activator of transcription 5A JBrowse link 10 88,764,732 88,789,060 RGD:6480464
G Sult1e1 sulfotransferase family 1E member 1 JBrowse link 14 22,070,861 22,089,264 RGD:6480464
G Synpo synaptopodin JBrowse link 18 55,863,081 55,921,412 RGD:6480464
G Tbx19 T-box transcription factor 19 JBrowse link 13 83,403,263 83,426,305 RGD:6480464
G Tff1 trefoil factor 1 JBrowse link 20 9,892,124 9,895,984 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Thra thyroid hormone receptor alpha JBrowse link 10 86,657,285 86,684,935 RGD:6480464
G Tmem183a transmembrane protein 183A JBrowse link 13 51,184,647 51,201,401 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Txnip thioredoxin interacting protein JBrowse link 2 198,683,168 198,686,971 RGD:6480464
G Tyr tyrosinase JBrowse link 1 151,012,598 151,106,802 RGD:6480464
G Ube2f ubiquitin-conjugating enzyme E2F (putative) JBrowse link 9 98,394,112 98,428,684 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:6480464
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 9 95,285,592 95,302,822 RGD:6480464
G Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C JBrowse link 9 95,233,957 95,302,822 RGD:6480464
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 9 95,221,474 95,302,822 RGD:6480464
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 JBrowse link 14 22,597,103 22,619,968 RGD:6480464
G Utp6 UTP6 small subunit processome component JBrowse link 10 67,255,177 67,285,754 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Vtcn1 V-set domain containing T cell activation inhibitor 1 JBrowse link 2 203,200,435 203,274,264 RGD:6480464
G Wars1 tryptophanyl-tRNA synthetase 1 JBrowse link 6 132,771,026 132,802,262 RGD:6480464
G Zfp688 zinc finger protein 688 JBrowse link 1 198,865,950 198,869,068 RGD:6480464
estriol 16-O-(beta-D-glucuronide) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb1a ATP binding cassette subfamily B member 1A JBrowse link 4 22,339,829 22,517,642 RGD:6480464
estriol 3-O-(beta-D-glucuronide) term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kl Klotho JBrowse link 12 942,974 987,206 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        molecular messenger 17946
          hormone 17752
            sex hormone 17605
              estrogen 17524
                estriol 125
                  3-(allyloxy)estra-1,3,5(10)-triene-16alpha,17beta-diol 0
                  estriol 16-O-(beta-D-glucuronide) 1
                  estriol 3-O-(beta-D-glucuronide) 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic molecule 19337
                              organic cyclic compound 19089
                                organic polycyclic compound 16028
                                  steroid 12769
                                    hydroxy steroid 12359
                                      16-hydroxy steroid 162
                                        16alpha-hydroxy steroid 158
                                          estriol 125
                                            3-(allyloxy)estra-1,3,5(10)-triene-16alpha,17beta-diol 0
                                            estriol 16-O-(beta-D-glucuronide) 1
                                            estriol 3-O-(beta-D-glucuronide) 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.