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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:melibiose
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Accession:CHEBI:28053 term browser browse the term
Definition:A glycosylglucose formed by an alpha-(1->6)-linkage between D-galactose and D-glucose.
Synonyms:exact_synonym: alpha-D-galactopyranosyl-(1->6)-D-glucopyranose
 related_synonym: (Gal)1 (Glc)1;   6-O-alpha-D-galactopyranosyl-D-glucopyranose;   D-Melibiose;   D-mellibiose;   Formula=C12H22O11;   Gal-alpha(1,6)Glc;   InChI=1S/C12H22O11/c13-1-3-5(14)8(17)10(19)12(23-3)21-2-4-6(15)7(16)9(18)11(20)22-4/h3-20H,1-2H2/t3-,4-,5+,6-,7+,8+,9-,10-,11?,12+/m1/s1;   InChIKey=DLRVVLDZNNYCBX-ABXHMFFYSA-N;   SMILES=OC[C@H]1O[C@H](OC[C@H]2OC(O)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1O;   alpha-D-Gal-(1->6)-D-Glc;   alpha-D-Galp-(1->6)-D-Glcp;   alpha-D-galactosyl-(1->6)-D-glucose
 alt_id: CHEBI:20943;   CHEBI:25182;   CHEBI:60170;   CHEBI:6733
 xref: Beilstein:1292781;   CAS:585-99-9;   GlyTouCan:G09165XB;   Gmelin:887780;   HMDB:HMDB0000048;   KEGG:C05402;   KEGG:G01275;   KNApSAcK:C00001142;   MetaCyc:MELIBIOSE;   PMID:12797744;   PMID:17006649;   PMID:17724458;   PMID:19846069;   PMID:19913595;   PMID:27577255;   PMID:27794607;   PMID:28453942;   PMID:3290105;   PMID:718021;   PMID:7524207;   Reaxys:1292781;   Wikipedia:Melibiose


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royal jelly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA] CTD PMID:30896085 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of CASP3 mRNA] CTD PMID:30896085 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions EXP
ISO
royal jelly inhibits the reaction [Cisplatin results in decreased activity of CAT protein]
royal jelly inhibits the reaction [Nicotine results in decreased activity of CAT protein]
CTD PMID:20369241, PMID:30896085 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
affects binding
ISO Estradiol inhibits the reaction [royal jelly binds to ESR1 protein]; royal jelly binds to and results in increased activity of ESR1 protein; royal jelly inhibits the reaction [Estradiol binds to ESR1 protein]
royal jelly results in increased activity of ESR1 protein
CTD PMID:15946813, PMID:17287592 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding
ISO Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein] CTD PMID:15946813, PMID:17287592 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of PCNA protein] CTD PMID:30896085 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO royal jelly results in increased expression of TFF1 mRNA CTD PMID:15946813 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] CTD PMID:30896085 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO
EXP
royal jelly results in increased expression of VEGFA mRNA CTD PMID:15946813, PMID:17287592 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        pharmacological role 18825
          agonist 18223
            elastin-laminin receptor agonist 9
              melibiose 9
                alpha-D-Galp-(1->3)-[alpha-D-Galp-(1->6)]-D-Glcp 0
                beta-melibiose 0
                melibionic acid 0
                royal jelly 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            heteroorganic entity 19184
                              organochalcogen compound 18894
                                organooxygen compound 18816
                                  carbohydrates and carbohydrate derivatives 12191
                                    carbohydrate 12191
                                      oligosaccharide 516
                                        disaccharide 425
                                          glycosylglucose 180
                                            melibiose 9
                                              alpha-D-Galp-(1->3)-[alpha-D-Galp-(1->6)]-D-Glcp 0
                                              beta-melibiose 0
                                              melibionic acid 0
                                              royal jelly 9
paths to the root

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