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Accession:CHEBI:28077 term browser browse the term
Definition:A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei)
Synonyms:exact_synonym: (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-6,23-dioxo-8,30-dioxa-24-azatetracyclo[,7).0(5,28)]triaconta-1(28),1(29),2,4,9,19,21,25,27-nonaen-13-yl acetate
 related_synonym: 3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV;   Formula=C43H58N4O12;   InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1;   InChIKey=JQXXHWHPUNPDRT-WLSIYKJHSA-N;   RFP;   Rifampin;   SMILES=CO[C@H]1\\C=C\\O[C@@]2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)\\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c(\\C=N\\N1CCN(C)CC1)c(O)c4c3C2=O;   rifamcin;   rifampicina;   rifampicinum
 alt_id: CHEBI:26577;   CHEBI:45308;   CHEBI:8858
 xref: Beilstein:5723476 "Beilstein";   CAS:13292-46-1 "ChemIDplus";   CAS:13292-46-1 "KEGG COMPOUND";   DrugBank:DB01045;   HMDB:HMDB0015179;   KEGG:C06688;   KEGG:D00211
 xref_mesh: MESH:D012293
 xref: PDBeChem:RFP;   PMID:11600355 "Europe PMC";   PMID:14665784 "Europe PMC";   PMID:14670633 "Europe PMC";   PMID:15331348 "Europe PMC";   PMID:15383168 "Europe PMC";   PMID:15705662 "Europe PMC";   PMID:16159084 "Europe PMC";   PMID:16515773 "Europe PMC";   PMID:17828712 "Europe PMC";   PMID:18332862 "Europe PMC";   PMID:19386087 "Europe PMC";   PMID:19458074 "Europe PMC";   PMID:19723399 "Europe PMC";   PMID:24718527 "Europe PMC";   PMID:26725427 "Europe PMC";   PMID:26819743 "Europe PMC";   PMID:27082586 "Europe PMC";   PMID:27143080 "Europe PMC";   PMID:27182275 "Europe PMC";   PMID:27242224 "Europe PMC";   PMID:27470132 "Europe PMC";   PMID:27569735 "Europe PMC";   PMID:27617596 "Europe PMC";   PMID:27640793 "Europe PMC";   PMID:27755552 "Europe PMC";   PMID:27795624 "Europe PMC";   PMID:27883163 "Europe PMC";   PMID:27965540 "Europe PMC";   PMID:27993874 "Europe PMC";   PMID:28081169 "Europe PMC";   PMID:28118809 "Europe PMC";   PMID:28181840 "Europe PMC";   PMID:28184157 "Europe PMC";   PMID:28207542 "Europe PMC";   PMID:28262820 "Europe PMC";   Patent:NL6509961;   Patent:US3342810;   Reaxys:5723476 "Reaxys";   Wikipedia:Rifampicin
 cyclic_relationship: is_tautomer_of CHEBI:71365

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rifampicin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ABCB1 ATP binding cassette subfamily B member 1 JBrowse link 14 13,644,891 13,852,829 RGD:6480464
G NR1I2 nuclear receptor subfamily 1 group I member 2 JBrowse link 33 23,444,367 23,456,405 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 223
    role 223
      application 188
        pharmaceutical 185
          drug 185
            antineoplastic agent 72
              rifampicin 2
                2'-hydroxyrifampicin 0
                21-phosphorifampicin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 223
    subatomic particle 223
      composite particle 223
        hadron 223
          baryon 223
            nucleon 223
              atomic nucleus 223
                atom 223
                  main group element atom 216
                    p-block element atom 216
                      carbon group element atom 205
                        carbon atom 204
                          organic molecular entity 204
                            organic group 153
                              organic divalent group 152
                                organodiyl group 152
                                  carbonyl group 152
                                    carbonyl compound 152
                                      carboxylic acid 112
                                        carboacyl group 47
                                          univalent carboacyl group 47
                                            carbamoyl group 44
                                              carboxamide 44
                                                lactam 4
                                                  ansamycin 2
                                                    rifamycins 2
                                                      rifampicin 2
                                                        2'-hydroxyrifampicin 0
                                                        21-phosphorifampicin 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.