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Term:6-oxoprostaglandin F1alpha
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Accession:CHEBI:28158 term browser browse the term
Definition:A prostaglandin Falpha that is prostaglandin F1alpha bearing a keto substituent at the 6-position.
Synonyms:exact_synonym: (13E,15S)-9alpha,11alpha,15-trihydroxy-6-oxoprost-13-en-1-oic acid
 related_synonym: 6-Keto-PGF1a;   6-Keto-PGF1alpha;   6-Keto-prostaglandin F1a;   6-Keto-prostaglandin F1alpha;   6-Ketoprostaglandin F1alpha;   6-Oxo-PGF1alpha;   6-oxo-prostaglandin F1alpha;   Formula=C20H34O6;   InChI=1S/C20H34O6/c1-2-3-4-7-14(21)10-11-16-17(19(24)13-18(16)23)12-15(22)8-5-6-9-20(25)26/h10-11,14,16-19,21,23-24H,2-9,12-13H2,1H3,(H,25,26)/b11-10+/t14-,16+,17+,18+,19-/m0/s1;   InChIKey=KFGOFTHODYBSGM-ZUNNJUQCSA-N;   SMILES=CCCCC[C@H](O)\\C=C\\[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC(=O)CCCCC(O)=O
 alt_id: CHEBI:20736;   CHEBI:2205
 xref: CAS:58962-34-8 "ChemIDplus";   CAS:58962-34-8 "KEGG COMPOUND";   KEGG:C05961;   LIPID_MAPS_instance:LMFA03010001 "LIPID MAPS"
 xref_mesh: MESH:D015121
 xref: PMID:11034952 "Europe PMC";   PMID:11481608 "Europe PMC";   PMID:11510754 "Europe PMC";   PMID:11529335 "Europe PMC";   PMID:11798014 "Europe PMC";   PMID:12535846 "Europe PMC";   PMID:12912853 "Europe PMC";   PMID:14735492 "Europe PMC";   PMID:15108967 "Europe PMC";   PMID:15550787 "Europe PMC";   PMID:15684771 "Europe PMC";   PMID:15883739 "Europe PMC";   PMID:18942642 "Europe PMC";   PMID:6107345 "Europe PMC";   PMID:6132981 "Europe PMC";   PMID:7864124 "Europe PMC";   PMID:9013819 "Europe PMC";   Reaxys:2821925 "Reaxys"
 cyclic_relationship: is_conjugate_acid_of CHEBI:133451

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6-oxoprostaglandin F1alpha term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Alox15 arachidonate 15-lipoxygenase JBrowse link 10 56,953,692 56,962,145 RGD:6480464
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:6480464
G Avp arginine vasopressin JBrowse link 3 123,117,482 123,119,460 RGD:6480464
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G Klkb1 kallikrein B1 JBrowse link 16 50,151,127 50,175,407 RGD:6480464
G Kng2 kininogen 2 JBrowse link 11 81,509,185 81,516,759 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Ptgis prostaglandin I2 synthase JBrowse link 3 163,950,746 163,986,129 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        biochemical role 19133
          metabolite 19101
            eukaryotic metabolite 18744
              animal metabolite 18484
                mammalian metabolite 18465
                  mouse metabolite 17887
                    6-oxoprostaglandin F1alpha 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    subatomic particle 19658
      composite particle 19658
        hadron 19658
          baryon 19658
            nucleon 19658
              atomic nucleus 19658
                atom 19658
                  main group element atom 19539
                    p-block element atom 19539
                      carbon group element atom 19422
                        carbon atom 19414
                          organic molecular entity 19414
                            organic group 18340
                              organic divalent group 18330
                                organodiyl group 18330
                                  carbonyl group 18217
                                    carbonyl compound 18217
                                      carboxylic acid 17921
                                        monocarboxylic acid 17256
                                          fatty acid 15817
                                            fatty acid derivative 1011
                                              icosanoid 451
                                                prostanoid 394
                                                  prostaglandin 389
                                                    prostaglandins F 97
                                                      prostaglandins Falpha 96
                                                        prostaglandin F1alpha 13
                                                          6-oxoprostaglandin F1alpha 12
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.