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ONTOLOGY REPORT - ANNOTATIONS


Term:novobiocin
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Accession:CHEBI:28368 term browser browse the term
Definition:A coumarin-derived antibiotic obtained from Streptomyces niveus.
Synonyms:related_synonym: Formula=C31H36N2O11;   InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1;   InChIKey=YJQPYGGHQPGBLI-KGSXXDOSSA-N;   N-{7-[(3-O-carbamoyl-6-deoxy-5-methyl-4-O-methyl-beta-D-gulopyranosyl)oxy]-4-hydroxy-8-methyl-2-oxo-2H-chromen-3-yl}-4-hydroxy-3-(3-methylbut-2-en-1-yl)benzamide;   SMILES=CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C;   novobiocina;   novobiocine;   novobiocinum
 alt_id: CHEBI:25597;   CHEBI:44505;   CHEBI:7644
 xref: CAS:303-81-1 "ChemIDplus";   CAS:303-81-1 "KEGG COMPOUND";   DrugBank:DB01051;   Drug_Central:1974 "DrugCentral";   HMDB:HMDB0015185;   KEGG:C05080;   KNApSAcK:C00002487;   LINCS:LSM-5910
 xref_mesh: MESH:D009675
 xref: PDBeChem:NOV;   PMID:17132020 "Europe PMC";   PMID:18418407 "Europe PMC";   PMID:19282394 "Europe PMC";   PMID:19762445 "Europe PMC";   PMID:20325309 "Europe PMC";   PMID:21388139 "Europe PMC";   PMID:22897434 "Europe PMC";   PMID:26844397 "Europe PMC";   PMID:26926630 "Europe PMC";   PMID:27829510 "Europe PMC";   PMID:27914946 "Europe PMC";   PMID:28246042 "Europe PMC";   PMID:28316592 "Europe PMC";   PMID:9687383 "Europe PMC";   Patent:WO2012049521;   Patent:WO2012103487;   Reaxys:1445842 "Reaxys"
 cyclic_relationship: is_conjugate_acid_of CHEBI:71339


show annotations for term's descendants       view all columns           Sort by:
 
novobiocin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Cd38 CD38 molecule JBrowse link 14 71,714,768 71,754,990 RGD:6480464
G Cdh2 cadherin 2 JBrowse link 18 8,146,971 8,366,037 RGD:6480464
G Ggt1 gamma-glutamyltransferase 1 JBrowse link 20 14,019,723 14,045,781 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19716
    role 19663
      biological role 19661
        antimicrobial agent 17199
          novobiocin 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19716
    subatomic particle 19712
      composite particle 19712
        hadron 19712
          baryon 19712
            nucleon 19712
              atomic nucleus 19712
                atom 19712
                  main group element atom 19598
                    p-block element atom 19598
                      carbon group element atom 19486
                        carbon atom 19480
                          organic molecular entity 19480
                            organic group 18407
                              organic divalent group 18397
                                organodiyl group 18397
                                  carbonyl group 18285
                                    carbonyl compound 18285
                                      carboxylic acid 17940
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16630
                                              carboxamide 16630
                                                monocarboxylic acid amide 13200
                                                  novobiocin 5
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