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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:(+)-dihydromyricetin
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Accession:CHEBI:28429 term browser browse the term
Definition:An optically active form of dihydromyricetin having (2R,3R)-configuration.
Synonyms:exact_synonym: (2R,3R)-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-2,3-dihydro-4H-chromen-4-one
 related_synonym: (2R,3R)-2,3-dihydro-3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4-one;   (2R,3R)-3,3',4',5,5',7-hexahydroxy-2,3-dihydroflavanonol;   (2R,3R)-3,5,7,3',4',5'-hexahydroxyflavanone;   (2R,3R)-dihydromyricetin;   Ampelopsin;   Ampeloptin;   Formula=C15H12O8;   InChI=1S/C15H12O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,14-20,22H/t14-,15+/m0/s1;   InChIKey=KJXSIXMJHKAJOD-LSDHHAIUSA-N;   SMILES=O[C@@H]1[C@H](Oc2cc(O)cc(O)c2C1=O)c1cc(O)c(O)c(O)c1
 alt_id: CHEBI:18447;   CHEBI:21
 xref: Beilstein:4331256;   Beilstein:5303758;   CAS:27200-12-0;   KEGG:C02906;   KNApSAcK:C00000938
 xref_mesh: MESH:C106407
 xref: MetaCyc:CPD-7087;   PMID:12889119;   PMID:17059013;   PMID:22693649;   Reaxys:5303758;   Wikipedia:Dihydromyricetin
 cyclic_relationship: is_enantiomer_of CHEBI:48027


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(+)-dihydromyricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein] CTD PMID:21871475 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:21871475 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein] CTD PMID:21871475 NCBI chr18:56,364,586...56,406,381
Ensembl chr18:56,364,620...56,406,381
JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 3:156,727,642...156,758,307
Ensembl chr 3:156,727,642...156,758,307
JBrowse link
G Sphk1 sphingosine kinase 1 decreases expression
decreases activity
ISO ampelopsin results in decreased expression of SPHK1 protein
ampelopsin results in decreased activity of SPHK1 protein
CTD PMID:22251058 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link

Term paths to the root
Path 1
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  CHEBI ontology 19816
    role 19764
      chemical role 19288
        antioxidant 14226
          (+)-dihydromyricetin 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                organic heterocyclic compound 18432
                                  oxacycle 17200
                                    benzopyran 10142
                                      1-benzopyran 9858
                                        flavonoid 6376
                                          flavones 4169
                                            hydroxyflavone 4157
                                              flavonols 4071
                                                7-hydroxyflavonol 4050
                                                  myricetin 108
                                                    dihydromyricetin 6
                                                      (+)-dihydromyricetin 6
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