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ONTOLOGY REPORT - ANNOTATIONS


Term:thromboxane B2
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Accession:CHEBI:28728 term browser browse the term
Definition:A member of the class of thromboxanes B that is (5Z,13E)-thromboxa-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9, 11 and 15.
Synonyms:exact_synonym: (5Z,13E,15S)-9alpha,11,15-trihydroxythromboxa-5,13-dien-1-oic acid
 related_synonym: Formula=C20H34O6;   InChI=1S/C20H34O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,20-22,25H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+,20?/m0/s1;   InChIKey=XNRNNGPBEPRNAR-JQBLCGNGSA-N;   SMILES=CCCCC[C@H](O)\\C=C\\[C@H]1OC(O)C[C@H](O)[C@@H]1C\\C=C/CCCC(O)=O;   TXB2
 alt_id: CHEBI:26994;   CHEBI:9576
 xref: CAS:54397-85-2 "ChemIDplus";   CAS:54397-85-2 "KEGG COMPOUND";   HMDB:HMDB0003252;   KEGG:C05963;   LIPID_MAPS_instance:LMFA03030002 "LIPID MAPS"
 xref_mesh: MESH:D013929
 xref: PMID:24433337 "Europe PMC";   PMID:24786190 "Europe PMC";   PMID:7847191 "Europe PMC";   Reaxys:1399489 "Reaxys";   Wikipedia:Thromboxane_B2
 cyclic_relationship: is_conjugate_acid_of CHEBI:90696


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thromboxane B2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Tbxas1 thromboxane A synthase 1 JBrowse link 4 66,624,181 66,846,745 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
11-dehydro-thromboxane B2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apoe apolipoprotein E JBrowse link 1 80,612,894 80,616,820 RGD:6480464
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          metabolite 19106
            eukaryotic metabolite 18748
              animal metabolite 18486
                mammalian metabolite 18468
                  mouse metabolite 17880
                    thromboxane B2 9
                      11-dehydro-thromboxane B2 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        monocarboxylic acid 17256
                                          fatty acid 15814
                                            fatty acid derivative 1008
                                              icosanoid 450
                                                prostanoid 393
                                                  thromboxane 14
                                                    thromboxanes B 9
                                                      thromboxane B2 9
                                                        11-dehydro-thromboxane B2 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.