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ONTOLOGY REPORT - ANNOTATIONS


Term:picolinic acid
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Accession:CHEBI:28747 term browser browse the term
Definition:A pyridinemonocarboxylic acid in which the carboxy group is located at position 2. It is an intermediate in the metabolism of tryptophan.
Synonyms:related_synonym: 2-Picolinic acid;   2-Pyridinecarboxylic acid;   2-carboxypyridine;   Formula=C6H5NO2;   InChI=1S/C6H5NO2/c8-6(9)5-3-1-2-4-7-5/h1-4H,(H,8,9);   InChIKey=SIOXPEMLGUPBBT-UHFFFAOYSA-N;   PYRIDINE-2-CARBOXYLIC ACID;   SMILES=OC(=O)c1ccccn1;   alpha-picolinic acid;   alpha-pyridinecarboxylic acid;   o-pyridinecarboxylic acid
 alt_id: CHEBI:26128;   CHEBI:47159;   CHEBI:8201
 xref: Beilstein:109595 "Beilstein";   CAS:98-98-6 "ChemIDplus";   CAS:98-98-6 "KEGG COMPOUND";   CAS:98-98-6 "NIST Chemistry WebBook";   Gmelin:3318 "Gmelin";   HMDB:HMDB0002243;   KEGG:C10164;   KNApSAcK:C00002063
 xref_mesh: MESH:C030614
 xref: MetaCyc:PICOLINATE;   PDBeChem:6PC;   PMID:15206716 "Europe PMC";   PMID:15206793 "Europe PMC";   PMID:15290459 "Europe PMC";   PMID:16303883 "Europe PMC";   PMID:23630570 "Europe PMC";   PMID:24119749 "Europe PMC";   PMID:7064867 "Europe PMC";   PMID:7969932 "Europe PMC";   Reaxys:109595 "Reaxys";   Wikipedia:Picolinic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:38184


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picolinic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abca1 ATP binding cassette subfamily A member 1 JBrowse link 5 69,857,717 69,983,042 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Hba-a2 hemoglobin alpha, adult chain 2 JBrowse link 10 15,589,364 15,590,207 RGD:6480464
G Hspd1 heat shock protein family D (Hsp60) member 1 JBrowse link 9 61,680,529 61,691,202 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:6480464
G Igf1r insulin-like growth factor 1 receptor JBrowse link 1 128,924,921 129,213,816 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Retn resistin JBrowse link 12 2,201,909 2,203,649 RGD:6480464
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Ubc ubiquitin C JBrowse link 12 36,638,457 36,642,734 RGD:6480464
G Ucp3 uncoupling protein 3 JBrowse link 1 165,482,912 165,495,895 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19654
    role 19598
      application 19220
        MALDI matrix material 909
          picolinic acid 21
            5-(2'-carboxyethyl)-4,6-dihydroxypicolinic acid 0
            5-(2'-formylethyl)-4,6-dihydroxypicolinic acid 0
            5-(3'-carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinic acid 0
            5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylic acid 0
            aminopyralid 0
            clopyralid 0
            picolinamide 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic group 18331
                              organic divalent group 18321
                                organodiyl group 18321
                                  carbonyl group 18209
                                    carbonyl compound 18209
                                      carboxylic acid 17908
                                        monocarboxylic acid 17245
                                          pyridinemonocarboxylic acid 363
                                            picolinic acid 21
                                              5-(2'-carboxyethyl)-4,6-dihydroxypicolinic acid 0
                                              5-(2'-formylethyl)-4,6-dihydroxypicolinic acid 0
                                              5-(3'-carboxy-3'-oxopropenyl)-4,6-dihydroxypicolinic acid 0
                                              5-(3-carboxy-3-oxopropenyl)-4,6-dihydroxypyridine-2-carboxylic acid 0
                                              aminopyralid 0
                                              clopyralid 0
                                              picolinamide 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.