Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:2,4,6-trichlorophenol
go back to main search page
Accession:CHEBI:28755 term browser browse the term
Definition:A trichlorophenol with phenolic substituents on positions 2, 4 and 6.
Synonyms:related_synonym: 1,3,5-Trichloro-2-hydroxybenzene;   2,4,6-TCP;   Formula=C6H3Cl3O;   InChI=1S/C6H3Cl3O/c7-3-1-4(8)6(10)5(9)2-3/h1-2,10H;   InChIKey=LINPIYWFGCPVIE-UHFFFAOYSA-N;   SMILES=Oc1c(Cl)cc(Cl)cc1Cl
 alt_id: CHEBI:19334;   CHEBI:898
 xref: Beilstein:776729;   CAS:88-06-2;   Gmelin:3766;   KEGG:C07098
 xref_mesh: MESH:C024564
 xref: MetaCyc:TRICHLOROPHENOL;   PDBeChem:T6C;   PMID:21863115;   PMID:22748215;   PMID:23995979;   PMID:24078273;   Reaxys:776729;   UM-BBD_compID:c0330;   Wikipedia:2\,4\,6-Trichlorophenol
 cyclic_relationship: is_conjugate_acid_of CHEBI:140426


show annotations for term's descendants           Sort by:
 
2,4,6-trichlorophenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of CYP11A1 mRNA CTD PMID:21296122 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of CYP19A1 mRNA CTD PMID:21296122 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of HSD17B4 mRNA CTD PMID:21296122 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of HSD3B1 mRNA CTD PMID:21296122
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO 2,4,6-trichlorophenol binds to PPARG protein CTD PMID:25314719 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rxrb retinoid X receptor beta multiple interactions ISO 2,4,6-trichlorophenol inhibits the reaction [alitretinoin binds to and results in increased activity of RXRB protein] CTD PMID:27565853 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression ISO 2,4,6-trichlorophenol results in decreased expression of STAR mRNA CTD PMID:21296122 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO 2,4,6-trichlorophenol inhibits the reaction [Triiodothyronine binds to THRB protein] CTD PMID:29409039 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    role 19764
      biological role 19764
        aetiopathogenetic role 18960
          carcinogenic agent 18331
            2,4,6-trichlorophenol 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic molecule 19522
                              organic cyclic compound 19320
                                carbocyclic compound 18222
                                  benzenoid aromatic compound 17254
                                    benzenes 17010
                                      chlorobenzenes 13342
                                        chlorophenol 1174
                                          trichlorophenols 12
                                            trichlorophenol 12
                                              2,4,6-trichlorophenol 8
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.