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Accession:CHEBI:28864 term browser browse the term
Definition:A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring.
Synonyms:exact_synonym: (1S,2S,3R,4S,6R)-4,6-diamino-3-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribo-hexopyranosyloxy)-2-hydroxycyclohexyl 3-amino-3-deoxy-alpha-D-glucopyranoside
 related_synonym: 3'-Deoxykanamycin B;   Formula=C18H37N5O9;   InChI=1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11-,12+,13+,14-,15+,16-,17+,18+/m0/s1;   InChIKey=NLVFBUXFDBBNBW-PBSUHMDJSA-N;   Nebramycin 6;   Nebramycin factir 6;   O-3-Amino-3-deoxy-alpha-D-glucopyranosyl-(1-4)-O-(2,6-diamino-2,3,6-trideoxy-alpha-D-ribohexopyranosyl-(1-4))-2-deoxy-D-streptamine;   SMILES=NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O;   Tobracin (TN);   Tobrex (TN)
 alt_id: CHEBI:19849;   CHEBI:45933;   CHEBI:9610
 xref: CAS:32986-56-4 "ChemIDplus";   CAS:32986-56-4 "KEGG COMPOUND";   DrugBank:DB00684;   Drug_Central:2684 "DrugCentral";   KEGG:C00397;   KEGG:D00063;   LINCS:LSM-6534
 xref_mesh: MESH:D014031
 xref: PDBeChem:TOY;   PMID:11000679 "Europe PMC";   PMID:11072877 "Europe PMC";   PMID:11459219 "Europe PMC";   PMID:11478352 "Europe PMC";   PMID:14961139 "Europe PMC";   PMID:15813341 "Europe PMC";   PMID:16205136 "Europe PMC";   PMID:16239129 "Europe PMC";   PMID:16478137 "Europe PMC";   PMID:16650821 "Europe PMC";   PMID:17150225 "Europe PMC";   PMID:18331849 "Europe PMC";   PMID:19072156 "Europe PMC";   PMID:19220547 "Europe PMC";   PMID:19340717 "Europe PMC";   PMID:19465435 "Europe PMC";   PMID:20000576 "Europe PMC";   PMID:20884302 "Europe PMC";   PMID:20938669 "Europe PMC";   PMID:21275493 "Europe PMC";   PMID:21343445 "Europe PMC";   PMID:21357290 "Europe PMC";   PMID:21396748 "Europe PMC";   PMID:21414310 "Europe PMC";   PMID:21429824 "Europe PMC";   PMID:21438171 "Europe PMC";   PMID:21530479 "Europe PMC";   PMID:21592592 "Europe PMC";   PMID:21726492 "Europe PMC";   PMID:21756818 "Europe PMC";   PMID:21796931 "Europe PMC";   PMID:21815282 "Europe PMC";   Reaxys:1357507 "Reaxys";   Wikipedia:Tobramycin
 cyclic_relationship: is_conjugate_base_of CHEBI:73678

show annotations for term's descendants       view all columns           Sort by:
tobramycin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Anpep alanyl aminopeptidase, membrane JBrowse link 1 141,561,364 141,604,249 RGD:6480464
G B2m beta-2 microglobulin JBrowse link 3 114,087,287 114,093,311 RGD:6480464
G Ctsb cathepsin B JBrowse link 15 46,316,741 46,337,613 RGD:6480464
G Elane elastase, neutrophil expressed JBrowse link 7 12,638,320 12,640,168 RGD:6480464
G Gadd45a growth arrest and DNA-damage-inducible, alpha JBrowse link 4 97,782,512 97,784,814 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming JBrowse link 1 214,725,482 214,756,653 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19749
    role 19696
      biological role 19694
        antimicrobial agent 17222
          tobramycin 9
            nebramycin 5' 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19749
    subatomic particle 19745
      composite particle 19745
        hadron 19745
          baryon 19745
            nucleon 19745
              atomic nucleus 19745
                atom 19745
                  main group element atom 19630
                    p-block element atom 19630
                      carbon group element atom 19523
                        carbon atom 19517
                          organic molecular entity 19517
                            heteroorganic entity 19081
                              organochalcogen compound 18796
                                organooxygen compound 18708
                                  carbohydrates and carbohydrate derivatives 12115
                                    carbohydrate 12115
                                      carbohydrate derivative 11738
                                        glycosyl compound 10794
                                          glycoside 9143
                                            aminoglycoside 8357
                                              aminoglycoside antibiotic 2528
                                                kanamycins 24
                                                  kanamycin B 9
                                                    tobramycin 9
                                                      nebramycin 5' 0
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.